Matthew J. Ryan, MD

Matthew J. Ryan, MD, is a pediatric gastroenterologist in the Division of Gastroenterology, Hepatology and Nutrition at The Children's Hospital of Philadelphia.

Locations: Main Campus; Specialty Care & Surgery Center, Voorhees; Specialty Care, Princeton at Plainsboro
Phone: 215-590-3630

  • Education and Training

    Medical School

    MD - University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, NJ


    Pediatrics - The University of Chicago Children's Hospital, Chicago, IL


    Pediatrics - The University of Chicago Children's Hospital, Chicago, IL


    Pediatric Gastroenterology (Clinical and Research) - The Children's Hospital of Philadelphia, Philadelphia, PA

    Board Certification

    Pediatric Gastroenterology

  • Titles and Academic Titles

    Attending Physician

    Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

  • Departments and Services
  • Research Interests

    Pediatric liver disease
    Bile duct development
    Growth and remodeling
    Notch signaling

  • Publications




    Ryan JM: Vomiting, Splenomegaly and Asplenia/Hyposplenia. The Five Minute Pediatric Consult, 5th edition. Lippincott Williams and Wilkins, 2008.



    Ryan M, Underkoffler L, Dutton J, Loomes K: Delayed Biliary Development Leads to Bile Duct Proliferation and Portal Tract Expansion in Mice Heterozygous for Radical Fringe and Jag1 Alleles. Poster Presentation, AASLD annual meeting Boston, MA November 2012.

  • Awards and Honors

    2006-2008, CDHNF Young Investigator's Development Award
    2006, 2nd place Komorov Competition-basic science
    2004-2006, NIH Loan Repayment Program

  • Editorial and Academic Positions

    Editorial positions

    2011, Journal of Clinical Investigation, Ad hoc reviewer
    2010, Human Immunology, Ad hoc reviewer

    Academic and institutional committees

    2011-present, Division of GI, Hepatology and Nutrition Second Opinion Committee

  • Leaderships

    Memberships in professional organization

    American Association for the Study of Liver Diseases
    American Gastroenterology Association
    North American Society of Pediatric Gastroenterology, Hepatology and Nutrition

    • 2011-2013, Research Committee