Elizabeth B. Rand, MD

Elizabeth B. Rand, MD, is a pediatric gastroenterologist in the Division of Gastroenterology, Hepatology and Nutrition. She is the medical director of the Liver Transplant Program and the director of the Gastroenterology Fellowship Program at The Children's Hospital of Philadelphia.

Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

  • Background

    Dr. Rand's interests are in the clinical care of children with liver disease, particularly Alagille syndrome, biliary atresia and liver transplantation. Research interests include clinical studies of biliary atresia and studies of immunization, immune suppression and long-term outcome after transplantation. Basic science interests in liver development and fibrosis are carried out as collaborations with FSBLC scientists who utilize the liver tissue bank.

  • Education and Training

    Medical School

    MD - University of Chicago, Pritzker School of Medicine, Chicago, IL

    Internship

    Pediatrics - Johns Hopkins Hospital, Baltimore, MD

    Residency

    Pediatrics - Johns Hopkins Hospital, Baltimore, MD

    Fellowship

    Pediatric Gastroenterology, Hepatology & Nutrition - University of Chicago, Chicago, IL

    Additional Training

    Research Fellow - Howard Hughes Medical Institute, University of Chicago, Chicago, IL

    Board Certification

    Pediatric Gastroenterology
    Pediatric Transplant Hepatology
    Pediatrics

    Undergraduate Degree

    AB in Chemistry - University of Chicago, Chicago, IL

  • Titles and Academic Titles

    Medical Director, Liver Transplant Program

    Director, Gastroenterology and Nutrition Fellowship Program

    Associate Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

  • Centers and Programs
  • Research Interests

    Biliary development
    Liver disease

  • Publications

    Books

    Chapters

    2012

    Yeh H, Rand E: When mothers are better than fathers…. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 12(2): 279-80, Feb 2012.

    2011

    Rook M, Rand E: Predictors of long-term outcome after liver transplant. Curr Opin Organ Transplant 16(5): 499-504, October 2011.

    2010

    Kamath BM, Muir A, Rand EB: Nutritional Considerations in Pediatric Liver Transplant. Nutrition, Diet Therapy and the Liver. Preedy, Lakshman, Srirajaskanthan, and Watson (eds.). Taylor and Francis Group/CRC Press Publishers, Page: 307-319, 2010.

    2008

    Ryan MJ, Rand E: Primary Sclerosing Cholangitis. Pediatric Gastroenterology: The requisites in pediatrics. Liacouras and Piccoli (eds.). Mosby Elsevier Publishing, Page: 285-299, 2008.

    2007

    Kamath BM and Rand EB: Evaluation of the liver transplant candidate. Pediatric Solid Organ Transplantation. Fine, Ebber, Olthoff, Kelly and Harmon (eds.). Blackwell Publishing, Page: 207-212, 2007.

    2006

    Emerick KM, Chrisant MA and Rand EB: Transplant Emergencies. Textbook of Pediatric Emergency Medicine. Fleisher, Ludwig & Henretig (eds.). Lippincott Williams & Wilkins, Page: 1727-1736, 2006.

    2003

    Rand EB and Olthoff KA: Overview of Pediatric Liver Transplantation. Gastroenterology Clinics of North America 32(3): 913-29, 2003.

    2002

    Rand EB and Olthoff KA: Pediatric Liver Transplantation. Liver Transplantation. Michael Lucey (eds.). 2002.

    2001

    Rand EB: Biliary Atresia, Obstructive Jaundice. Fetal and Neonatal Secrets, Hanely & Belfus. Polin (eds.). June 2001.

    1999

    Rand EB: This liver is a giver: Wilson disease and living related liver transplantation. Invited Editorial, Pediatr Transplantation 3: 169-170, 1999.

    1998

    Rand EB: Percutaneous Liver Biopsy. Clinical Pediatric Gastroenterology. Altschuler & Liacouras (eds.). Churchill Livingstone, London, 1998.

    Rand EB: Alagille Syndrome. Clinical Pediatric Gastroenterology. Altschuler & Liacouras (eds.). Churchill Livingstone, London, 1998.

    1990

    Rand EB: Gastroenterology. Nutrition. The Harriet Lane Handbook, (12th Edition). Greene M (eds.). Year Book Medical Publishers Inc., Chicago, Page: 47-50 and 337-348, 1990.

    Abstracts

    2012

    Akimova T, Kamath B, Goebel J, Meyers EC, Rand EB, Bucuvalas JC, Hancock WW: Calcineurin inhibitor (CNI) use in pediatric liver and kidney transplant (Tx) patients is associated with increased risk of obesity and impaired T-regulatory (Treg) cell function American Association of Immunologists, Boston May 2012.

    Hancock WW, Kamath B, Goebel J, Meyers KEC, Rand EB, Bucuvalas JC, Hawkins A, Akimova T: Differential effects of calcineurin inhibitor (CNI) versus rapamycin therapy on FOXP3 methylation and T regulatory (Treg) cell numbers, function, phenotype and viability in clinical pediatric liver and kidney allograft recipients American Transplant Congress, Boston June 2012.

    Ruebner RL, Reese PP, Denburg MR, Rand EB, Abt PL, Furth SL: Risk factors for end stage kidney disease after pediatric liver transplantation. ATC oral presentation 2012; Young Investigator Award 2012.

    Papers

    2013

    Schwartz Matthew C, Sullivan Lisa M, Glatz Andrew C, Rand Elizabeth, Russo Pierre, Goldberg David J, Rome Jonathan J, Cohen Meryl S: Portal and sinusoidal fibrosis are common on liver biopsy after Fontan surgery. Pediatric cardiology 34(1): 135-42, Jan 2013.

    Squires Robert H, Dhawan Anil, Alonso Estella, Narkewicz Michael R, Shneider Benjamin L, Rodriguez-Baez Norberto, Olio Dominic Dell, Karpen Saul, Bucuvalas John, Lobritto Steven, Rand Elizabeth, Rosenthal Philip, Horslen Simon, Ng Vicky, Subbarao Girish, Kerkar Nanda, Rudnick David, Lopez M James, Schwarz Kathleen, Romero Rene, Elisofon Scott, Doo Edward, Robuck Patricia R, Lawlor Sharon, Belle Steven H: Intravenous N-acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: a placebo-controlled clinical trial. Hepatology (Baltimore, Md.) 57(4): 1542-9, Apr 2013.

    Mohammad S, Grimberg A, Rand E, Anand R, Yin W, Alonso EM: Long-Term Linear Growth and Puberty in Pediatric Liver Transplant Recipients. The Journal of Pediatrics 163(5): 1354-60, Nov 2013.

    2012

    Schwartz MC, Sullivan L, Cohen MS, Russo P, John AS, Guo R, Guttenberg Ma, Rand EB: Hepatic pathology may develop before the Fontan operation in children with functional single ventricle: an autopsy study. The Journal of Thoracic and Cardiovascular Surgery 143(4): 904-9, Apr 2012.

    Kamath Binita M, Yin Wanrong, Miller Heather, Anand Ravinder, Rand Elizabeth B, Alonso Estella, Bucuvalas John: Outcomes of liver transplantation in alagille syndrome: The split experience. Liver Transplantation 18(8): 940-948, August 2012.

    Cui R, Fayek SA, Rand EB, Feygin T, Khrichenko D, Shaked A: Central pontine myelinolysis: a case report and clinical-pathological review. Pediatric Transplantation 16(6): E251-6, Sept 2012.

    Rychik J, Veldtman G, Rand E, Russo P, Rome JJ, Krok K, Goldberg DJ, Cahill AM, Wells RG: The Precarious State of the Liver After a Fontan Operation: Summary of a Multidisciplinary Symposium. Pediatr Cardiol 33(7): 1001-12, Oct 2012.

    Akimova T, Kamath BM, Goebel J W, Meyers KEC, Rand EB, Hawkins A, Levine MH, Bucuvalas JC, Hancock WW: Differing effects of rapamycin or calcineurin inhibitor on T-regulatory cells in pediatric liver and kidney transplant recipients. American Journal of Transplantation 12(12): 3449-61, Dec 2012.

    Goldberg DJ, Dodds K, Avitabile CM, Glatz AC, Brodsky JL, Semeao EJ, Rand EB, Mancilla EE, Rychik J: Children With Protein-Losing Enteropathy After the Fontan Operation Are at Risk for Abnormal Bone Mineral Density. Pediatric Cardiology 33(8), Dec 2012.

    Ruebner R L, Reese P P, Denburg M R, Rand E B, Abt P L, Furth S L: Risk factors for end-stage kidney disease after pediatric liver transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 12(12): 3398-405, Dec 2012.

    Cárdenas Agustín M, Epelman Monica, Darge Kassa, Rand Elizabeth B, Anupindi Sudha A: Pre- and postoperative imaging of the Rex shunt in children: what radiologists should know. AJR. American journal of roentgenology 198(5): 1032-7, May 2012.

    2011

    Cui R, Fayek SA, Rand EB, Feygin T, Khrichenko D, Shaked A. Central pontine myelinolysis: a case report and clinical-pathological review. Pedatr Transplant.  Epub 2011 Oct 24. doi: 10.1111/j.1399-3046.2011.01591.x. Cited in PubMed; PMID 22023701. Read the abstract

    Schwartz MC, Sullivan L, Cohen MS, Russo P, John AS, Guo R, et al. Hepatic pathology may develop before the Fontan operation in children with functional single ventricle: an autopsy study. J Thorac Cardiovasc Surg. Epub 2011 Sep 26. Cited in PubMed; PMID 21955477. Read the abstract

    Mendizabal M, Reddy KR, Cassuto J, Olthoff KM, Faust TW, Makar GA, et al. Liver transplantation in patients with cystic fibrosis: analysis of United Network for Organ Sharing data. Liver Transpl. 2011 Mar; 17(3):243-50. doi: 10. 1002/lt22240. Cited in PubMed; PMID 21384506. Read the abstract

    2010

    Bunin N, Guzikowski V, Rand ER, Goldfarb S, Baluarte J, Meyers K, et al. Solid organ transplants following hematopoietic stem cell transplant in children. Pediatr Transplant. 2010 Dec;14(8):1030-5. doi: 10.1111/j.1399-3046.2010.01401.x. Epub 2010 Sep 15. Cited in PubMed; PMID 20846242. Read the abstract.

    Leyva-Vega M, Gerfen J, Thiel BD, Jurkiewicz D, Rand EB, Pawlowska J, et al. Genomic alterations in biliary atresia suggest region of potential disease susceptibility in 2q37.3. Am J Med Genet A. 2010 Apr;152A(4):886-95. Cited in PubMed; PMID 20358598. Read the abstract

    Kaye AJ, Rand EB, Munoz PS, Spinner NB, Flake AW, Kamath BM. Effect of Kasai procedure on hepatic outcome in Alagille syndrome. J Pediatr Gastroenterol Nutr. 2010 Jun 30. Cited in PubMed; PMID 20601899. Read the abstract

    Leyva-Vega M, Gerfen J, Thiel BD, Jurkiewicz D, Rand EB, Pawlowska J, et al. Genomic alterations in biliary atresia suggest region of potential disease susceptibility in 2q37.3. Am J Med Genet A. 2010 Apr;152A(4):886-95. Cited in PubMed; PMID 20358598. Read the abstract

  • Editorial and Academic Positions

    Editorial positions

    2007-present, Section Editor, Hepatology; Pediatric Update
    2006-present, Hospital Physician Pediatric Gastroenterology Board Review Manual
    2000-present, Pediatric Transplantation, Reviewer
    1998-present, Journal of Pediatric Gastroenterology and Nutrition, Reviewer

    Academic committees

    2012, Ad Hoc Interviewer, Medical School Admission Committee
    2009-present, Transplant Center Quality Assurance Committee
    2009-present, Transplant Center Steering Committee
    2006-2012, Institutional Review Board
    2000-present, Graduate Medical Education Committee