Inpatient Pathway for Treatment of the Febrile Young Infant

Blood Culture POSITIVE

Blood Culture Positive
Repeat Blood Culture
arrow
arrow
Gram Positive Organism
Gram Negative Organism
arrow
arrow
Vancomycin AND Cefotaxime Continue Ampicillin if < 29 Days
Cefotaxime AND Gentamicin
Continue Gram Positive coverage:
Vancomycin or Ampicillin
arrow
arrow
Final Identification & Susceptibilities
arrow
Tailor antibiotics
Determine duration of therapy
Duration of Intravenous Therapy for Uncomplicated Bacteremia
7 Days Neisseria meningitidis
10 Days Group B streptococci
Streptococcus pneumoniae (uncomplicated)
14 Days

E. coli & other Gram-negative bacilli
Bacteria monocytogenes
Streptococcus pneumoniae (complicated)

For Staphylococcus aureus contact Infectious Diseases