L. Charles Bailey, MD, PhD
Locations: Main Hospital
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)
Background
Dr. Bailey is a member of the Divisions of Oncology and Hematology at CHOP. His clinical focus is on leukemia and lymphoma, and particularly on acute lymphoblastic leukemia, the most common type of childhood cancer. He also works on improving quality of supportive care for children with cancer.
His research centers on the development of learning health systems, which are based on the principle that every time a patient receives care, we must use what we learn to improve our ability to care for children. In order to do this, we need to make better use of the information patients entrust to us as part of their care, and discover new ways to do effective research using clinical information, and to being the results of clinical research back to the care of patients.
Dr. Bailey’s work includes creating ways to share data across hospitals, to recognize the clinical implications of information gathered from different sources, and to provide support to clinicians in using this information more effectively.
Education and Training
Internship
Texas Children's Hospital, Houston, TX
Residency
Pediatrics - Baylor College of Medicine Affiliated Hospitals: Texas Children's Hospital & Ben Taub General Hospital, Houston, TX
Fellowship
Pediatric Hematology/Oncology - The Children's Hospital of Philadelphia, Philadelphia, PA
Board Certification
Clinical Informatics – American Board of PathologyHematology – American Board of Internal Medicine
Undergraduate Degree
MD - University of Pennsylvania Medical School, Philadelphia, PA
Graduate Degree
PhD in Cellular and Molecular Biology - University of Pennsylvania School of Medicine, Philadelphia, PA
Titles and Academic Titles
Attending Physician
Academic Investigator, Healthy Weight Program
Member, DBHi
Associate Professor of Clinical Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Conditions Treated
Departments and Services
Areas of Focus
Research Topics
Research Interests
Analyzing gene expression data using computers to discover patterns in different tissues and tumors.
Publications
Papers
2016
Freedman JL, Desai AV, Bailey LC, Aplenc R, Burnworth B, Zehentner BK, Teachey DT, Wertheim G: Atypical Chronic Myeloid Leukemia in Two Pediatric Patients. Pediatr Blood Cancer 63(1): 156-9, Jan 2016.
2015
Freedman JL, Reilly AF, Powell SC, Bailey LC: Quality improvement initiative to increase influenza vaccination in pediatric cancer patients. Pediatrics 135(2): e540-6, Feb 2015.
Dotson Jennifer L, Crandall Wallace V, Zhang Peixin, Forrest Christopher B, Bailey L Charles, Colletti Richard B, Kappelman Michael D: Feasibility and Validity of the Pediatric Ulcerative Colitis Activity Index in Routine Clinical Practice. Journal of pediatric gastroenterology and nutrition 60(2): 200-4, Feb 2015 Notes: doi: 10.1097/MPG.0000000000000568.
2014
Bailey L Charles, Forrest Christopher B, Zhang Peixin, Richards Thomas M, Livshits Alice, DeRusso Patricia A: Association of Antibiotics in Infancy With Early Childhood Obesity. JAMA pediatrics 168(11): 1063-1069, Nov 2014.
Gidengil Courtney, Mangione-Smith Rita, Bailey L Charles, Cawthon Mary Lawrence, McGlynn Elizabeth A, Nakamura Mari M, Schiff Jeffrey, Schuster Mark A, Schneider Eric C: Using Medicaid and CHIP claims data to support pediatric quality measurement: lessons from 3 centers of excellence in measure development. Academic pediatrics 14(5 Suppl): S76-81, Sep-Oct 2014.
Bailey L Charles, Mistry Kamila B, Tinoco Aldo, Earls Marian, Rallins Marjorie C, Hanley Kendra, Christensen Keri, Jones Meredith, Woods Donna: Addressing electronic clinical information in the construction of quality measures. Academic pediatrics 14(5 Suppl): S82-9, Sep-Oct 2014.
Forrest, Christopher; Crandall, Wallace; Bailey, Charles; Zhang,Peixin; Joffe, Marshall; Colletti, Richard; Adler, Jeremy; Baron, Howard;Berman, James; DelRosario, Fernando; Grossman, Andrew; Hoffenberg,Edward; Israel, Esther; Kim, Sandra; Lightdale, Jenifer R.; Margolis,Peter; Marsolo, Keith; Mehta, Devendra; Milov, David; Patel, Ashish;Tung, Jeanne; Kappelman, Michael: Effectiveness of Anti-TNFα for Crohn's Disease: Research in a Pediatric Learning Health System. Pediatrics Epub, June 2014.
Seif AE, Fisher BT, Li Y, Torp K, Rheam DP, Huang YS, Harris T, Shah A, Hall M, Fieldston ES, Kavcic M, Vujkovic M, Bailey LC, Kersun LS, Reilly AF, Rheingold SR, Walker DM, Aplenc R: Patient and hospital factors associated with induction mortality in acute lymphoblastic leukemia. Pediatr Blood Cancer 61(5): 846-52, May 2014.
Forrest CB, Margolis PA, Bailey LC, Marsolo K, Del Beccaro MA, Finkelstein JA, Milov DE, Vieland VJ, Wolf BA, Yu FB, Kahn MG: PEDSnet: a National Pediatric Learning Health System. J Am Med Inform Assoc May 2014.
de Blank P, Cole K, Kersun L, Green A, Wilkes J J, Belasco J, Bagatell R, Bailey L C, Fisher M J: FDG-PET in Two Cases of Neurofibromatosis Type 1 and Atypical Malignancies. Current oncology (Toronto, Ont.) 21(2): e345-8, Apr 2014.
Kahn Michael G, Bailey L Charles, Forrest Christopher B, Padula Michael A, Hirschfeld Steven: Building a common pediatric research terminology for accelerating child health research. Pediatrics 133(3): 516-25, Mar 2014.
Fisher BT, Harris T, Torp K, Seif AE, Shah A, Huang YV, Bailey LC, Kersun LS, Reilly AF, Rheingold SR, Walker D, Li Y, Aplenc R. Establishment of an 11-Year Cohort of 8733 Pediatric Patients Hospitalized at United States Free-standing Children's Hospitals With De Novo Acute Lymphoblastic Leukemia From Health Care Administrative Data. Med Care 52(1): e1-6, Jan 2014 Notes: doi: 10.1097/MLR.0b013e31824deff9.
Kahn MG, Bailey LC, Forrest CB, Padula MA, Hirschfeld S. Building a common pediatric research terminology for accelerating child health research. Pediatrics. 2014;133(3):516-525.
Abstracts
2015
Khare, R; Utidjian, L; Schulte, G; Marsolo, K; Bailey, C: Identifying and Understanding Data Quality Issues in a Pediatric Distributed Research Network. American Medical Informatics Association 2015, San Francisco, CA Nov 2015.
Utidjian, LH; Khare, R; Burrows, EK; Schulte, G; Deakyne, SJ; Marsolo, K; Reynolds, MM; Hoyt, RR; Patibanbla, N; Bailey, LC: Identifying and Understanding Data Quality Issues in a Pediatric Distributed Research Network American Academy of Pediatrics National Conference and Exposition, Council on Clinical Information Technology, Washington, DC October 2015.
Bailey, C; Fisher, B; Powell, S; Schast, AP; Minich, C; Reilly, A: Reducing Hospital Days in Oncology Patients with Fever. American Academy of Pediatrics National Conference and Exposition, Council on Quality Improvement and Patient Safety, Washington, DC Oct 2015.
Bailey, C; Fisher, B; Powell, S; Schast, AP; Minich, C; Reilly, A: Reducing Hospital Days in Oncology Patients with Fever. American Academy of Pediatrics National Conference and Exposition, Council on Quality Improvement and Patient Safety, Washington, DC Oct 2015.
Books
Chapters
2015
Bailey, L. Charles: Idiopathic Thrombocytopenic Purpura. 5 Minute Pediatric Consult, 7th ed. Lippincott Williams and Wilkins, 2015.
2008
Bailey, L. Charles: Idiopathic Thrombocytopenic Purpura. The Five Minute Pediatric Consult, 5th Ed. Schwartz, M.W., Bell, L.M., Bingham, P.M., Chung, E.K., Friedman, D.F., Tanel, R.E., Mamula, P., Loomes, K.M., and Mascarenhas, M. (eds.). Lippincott, Williams, & Wilkins, 2008.
Bailey, L. Charles: Mediastinal Mass. The Five Minute Pediatric Consult, 5th Ed. Schwartz, M.W., Bell, L.M., Bingham, P.M., Chung, E.K., Friedman, D.F., Tanel, R.E., Mamula, P., Loomes, K.M., and Mascarenhas, M. (eds.). Lippincott, Williams, & Wilkins, 2008.
Bailey, L. Charles: Langerhans Cell Histiocytosis. The Five Minute Pediatric Consult, 5th Ed. Schwartz, M.W., Bell, L.M., Bingham, P.M., Chung, E.K., Friedman, D.F., Tanel, R.E., Mamula, P., Loomes, K.M., and Mascarenhas, M. (eds.). Lippincott, Williams, and Wilkins, 2008.
Posters and Presentations
Lectures by Invitation
2016
Bailey C. PEDSnet: Using COAs from Electronic Health Records in Clinical Research. DIA/FDA Statistics Forum; 2016 Apr; Rockville, MD.
2015
Bailey C. Bright Future? Developmental Milestones for PEDSnet, St. Louis Children's Hospital Informatics Symposium; 2015 Oct; St. Louis, MO.
Bailey C. Using the EHR to Learn About Childhood Obesity. IOM Working Group Evaluating Approaches to Assessing Prevalence and Trends in Obesity; 2015 Jul; Washington, DC.
Bailey C. Building a Pediatric LHS. Kanter Family Foundation Leadership Conference: Connecting the Accomplishments toward the Learning Health System; 2015 Mar; Miami, FL.
Bailey C. Complexity and Data Diversity" panel, NIH BD2K Workshop on Community-based Data and Metadata Standards Development; 2015 Feb; Bethesda, MD.
2014
Bailey C. The Role of Patient-Centered Outcomes in a Learning Health System. American College of Rheumatology Annual Meeting; 2014 Nov; Boston, MA.
Awards and Honors
Awards and Memberships in Honorary Societies
2013, Faculty Teaching Honor Roll, The Children's Hospital of Philadelphia
2009, Faculty Teaching Honor Roll, The Children's Hospital of Philadelphia
2008, Faculty Teaching Honor Roll, The Children's Hospital of Philadelphia
2002, Reuben Pottash Fellow Teacher of the Year Award, The Children's Hospital of Philadelphia
1998, Theodore Friedmann Prize for Medical Research, University of Pennsylvania School of Medicine
1990-1998, Life & Health Insurance Medical Research Fund Graduate Fellowship
1987-1990, NIGMS MSTP Fellowship
1986, Phi Beta Kappa
1986, Sigma Xi
1986, Eugene Tavenner Prize in Classics, Washington University in St. Louis
Editorial and Academic Positions
Editorial Positions
Peer Reviewer
2013-present, PLOS ONE
2013-present, eGEMs (Generating Evidence & Methods to improve patient outcomes)
Academic and Institutional Committees
2013-present, CHOP Clinical Data Reporting and Quality Committee
2010-present, Oncology Pediatric Protocol Review Committee
2010-present, Clinical Informatics Council, The Children's Hospital of Philadelphia
2010-present, Oncology Clinical Affairs Committee
2008-present, Operative and Invasive Procedures Committee, The Children's Hospital of Philadelphia
2007-present, Clinical Decision Support Committee, The Children's Hospital of Philadelphia
2006-present, Oncology Chemotherapy Safety Committee, The Children's Hospital of Philadelphia
2005-present, Oncology Quality Improvement Committee, The Children's Hospital of Philadelphia
Leadership and Memberships
Memberships in Professional Organizations
2009-present, American Medical Informatics Association
2005-present, American Society of Pediatric Hematology/Oncology