Anaphylaxis Clinical Pathway — Emergency Department
Antihistamines (H1) relieve the symptoms, hives/itch, but do not relieve severe symptoms.
Addition of antihistamine (H2) may provide more symptomatic relief for pruritis and abdominal symptoms.
|Administer IV over 2 minutes|
For patients who respond well to epinephrine, the addition of steroids may not be necessary unless used to treat airway or respiratory disease. There is some thought that it may decrease the risk of biphasic reactions; however a 2020 systematic review failed to document a benefit.
- Anaphylaxis-a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis.
|Dexamethasone||PO||0.6||8 mg||Prednisone alternative
No second dose required