Clinical Research Study Finder

Children's Hospital of Philadelphia leads or participates in hundreds of clinical research studies and clinical trials. Many of the studies that are currently enrolling patients can be found in this database. Use this finder to learn more about the purpose of these studies and clinical trials, find out who can participate, and tell us you're interested in enrolling.

Find a Clinical Research Study

1 - 10 of 187

Imaging Cognition and Neurodevelopment (ICAN)

The purpose of this research study is to examine relationships between brain and behavior development in toddlers with and without autism who have older siblings. 

You may qualify for our study if you or your child's healthcare provider has concerns regarding your toddler's development (communication, motor, behavior, or social concerns or developmental concerns). Toddlers must have older biological sibling(s) without autism.

Blood Sugar Stability in Individuals with Hyperinsulinism

The purpose of the study is to evaluate blood sugar levels and beta-cell function in adolescents and adult with KATP hyperinsulinism whom did not undergo pancreatectomy. We will perform oral glucose tolerance tests, glucose potentiated arginine tests, and evaluate blood sugars in home environment by using continuous glucose monitoring for 10 days.

Leigh Syndrome Natural History Study

The Children’s Hospital of Philadelphia is conducting a Natural History Study in Leigh Syndrome.

 

Natural History Studies help researchers better understand disease and can support drug development.


You or your child may qualify for this study if you have been diagnosed with Leigh Syndrome and are between the ages of 0 and 75. 

Adolescent Communication of Emotion Study (ACES)

The purpose of this study is to understand how children and adolescents respond to different emotions and social situations. This study is open to children between the ages of 12-17 years old. We are looking for typically developing children as well as children who are diagnosed with autism spectrum disorder (ASD), anxiety or depression. Participation would consist of up to two in-person visits to the Center for Autism Research at CHOP to complete brief cognitive testing and participate in activities and interact with research staff. 

DoSES

This research is studying a vaccine against Mpox (formerly known as monkeypox) that is FDA approved for adults but not yet approved for children. The goal of the study is to determine if the vaccine protects children just as well as it protects adults. The study is also looking at the safety of the vaccine. This study is open to healthy adolescents, ages 12-17. In addition, adolescents with certain immunodeficiency diseases or other conditions, that are well controlled, are eligible to participate. 

Imaging Cognition and Neurodevelopment (ICAN)

The purpose of this research study is to examine relationships between brain and behavior development in toddlers with and without autism who have older siblings. 

You may qualify for our study if you or your child's healthcare provider has concerns regarding your toddler's development (communication, motor, behavior, or social concerns or developmental concerns). Toddlers must have older biological sibling(s) without autism.

Blood Sugar Stability in Individuals with Hyperinsulinism

The purpose of the study is to evaluate blood sugar levels and beta-cell function in adolescents and adult with KATP hyperinsulinism whom did not undergo pancreatectomy. We will perform oral glucose tolerance tests, glucose potentiated arginine tests, and evaluate blood sugars in home environment by using continuous glucose monitoring for 10 days.

Leigh Syndrome Natural History Study

The Children’s Hospital of Philadelphia is conducting a Natural History Study in Leigh Syndrome.

 

Natural History Studies help researchers better understand disease and can support drug development.


You or your child may qualify for this study if you have been diagnosed with Leigh Syndrome and are between the ages of 0 and 75. 

Adolescent Communication of Emotion Study (ACES)

The purpose of this study is to understand how children and adolescents respond to different emotions and social situations. This study is open to children between the ages of 12-17 years old. We are looking for typically developing children as well as children who are diagnosed with autism spectrum disorder (ASD), anxiety or depression. Participation would consist of up to two in-person visits to the Center for Autism Research at CHOP to complete brief cognitive testing and participate in activities and interact with research staff. 

DoSES

This research is studying a vaccine against Mpox (formerly known as monkeypox) that is FDA approved for adults but not yet approved for children. The goal of the study is to determine if the vaccine protects children just as well as it protects adults. The study is also looking at the safety of the vaccine. This study is open to healthy adolescents, ages 12-17. In addition, adolescents with certain immunodeficiency diseases or other conditions, that are well controlled, are eligible to participate. 


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