Vaccine Information Statements (VISs) are developed by the Centers for Disease Control and Prevention (CDC) and provide a standardized way to present basic information to patients about vaccine benefits and possible adverse events. Before a healthcare provider vaccinates a child or an adult with a dose of any vaccine containing diphtheria, tetanus, pertussis, measles, mumps, rubella, polio, hepatitis A, hepatitis B, Hib, influenza, pneumococcal conjugate, meningococcal ACWY, meningococcal B, rotavirus, human papillomavirus, or varicella vaccine, the provider is required by law (the National Childhood Vaccine Injury Act) to provide a copy of the VIS to the patient (or the parent/legal representative of the child) who is receiving the vaccine. For other vaccines not covered under the law (pneumococcal polysaccharide, zoster, and travel vaccines, excluding hepatitis A), giving a patient a VIS is recommended, but not required.

The VIS must be given to the patient before the dose of vaccine is administered and must be offered before every dose of the vaccine (i.e., not just the first dose). Usually a paper copy of the VIS is given, but it is also acceptable to have the patient read the VIS on an electronic device, such as computer screen, smart phone, or tablet, or on a laminated copy during the office visit, but the patient must also be offered a paper or an electronic copy of the VIS to take home.

Federal law requires not only that the clinician provide a VIS to the patient, but also that the date the VIS is given to the patient and the VIS publication date are recorded in the patient's chart. It is important to use the most recent version of a VIS.

VIS resources from IAC

The website of the Immunization Action Coalition has the following resources related to VISs, all of which are available at

VIS resources from CDC

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Materials in this section are updated as new information and vaccines become available. The Vaccine Education Center staff regularly reviews materials for accuracy.

You should not consider the information in this site to be specific, professional medical advice for your personal health or for your family's personal health. You should not use it to replace any relationship with a physician or other qualified healthcare professional. For medical concerns, including decisions about vaccinations, medications and other treatments, you should always consult your physician or, in serious cases, seek immediate assistance from emergency personnel.