Unfortunately, vaccine administration errors happen all too often. To avoid this situation, it is essential that all clinic staff members be well trained in proper vaccine administration technique. Avoiding vaccine administration errors will save your clinic time and money, as well as potential embarrassment. Most importantly, it can prevent your practice from having unprotected patients who must be recalled to have doses repeated.

The Immunization Action Coalition (IAC) receives frequent inquiries from healthcare professionals regarding vaccine administration errors and what to do about them. Some of the most common errors are:

  • Administering the wrong vaccine (e.g., DTaP vs. Tdap; PPSV vs. PCV; varicella vs. zoster)
  • Administering the wrong dose of vaccine for the patient’s age (e.g., pediatric HepB to an adult)
  • Administering vaccine by the wrong route (intramuscularly vs. subcutaneously)
  • Administering expired vaccine
  • Using the wrong diluent when mixing a vaccine or administering diluent alone
  • Administering a dose of vaccine to the wrong patient

To prevent these errors from happening, make sure that everyone who administers vaccines is properly trained and that you use standardized protocols for vaccine administration. The following resources can help with training for new staff, as well as for providing periodic refreshers for all staff members.


Immunization Techniques: Best Practices with Infants, Children and Adults. This 25-minute DVD was developed by the Immunization Branch, California Department of Public Health, and is available for a nominal charge from the Immunization Action Coalition (IAC). It provides excellent training for new staff members and is a first-rate refresher for experienced staff.

Print resources for administering vaccines from IAC

Several free print materials are available for downloading from IAC’s Administering Vaccines Web section. Some of the most utilized materials are:

Related resources from IAC and other organizations

Do you have a question about vaccine administration errors? Check out IAC's "Ask the Experts" archive for Q&As answered by CDC experts. If you are unable to find answers to your specific vaccine administration questions, e-mail CDC at nipinfo@cdc.gov or IAC at admin@immunize.org for answers.

Materials in this section are updated as new information and vaccines become available. The Vaccine Education Center staff regularly reviews materials for accuracy.

You should not consider the information in this site to be specific, professional medical advice for your personal health or for your family's personal health. You should not use it to replace any relationship with a physician or other qualified healthcare professional. For medical concerns, including decisions about vaccinations, medications and other treatments, you should always consult your physician or, in serious cases, seek immediate assistance from emergency personnel.