Ingredients in Meningococcal Vaccines
This page shows the ingredients in meningococcal vaccines currently available for use in the U.S.
Find out more about meningococcus and the vaccines that protect against it.
Meningococcal ACWY vaccines
| Vaccine name* | Antigen | Adjuvant | Stabilizers | Preservatives | Residual byproducts |
|---|---|---|---|---|---|
| MenQuadfi | Polysaccharide coatings from meningococcus A, C, W, Y linked to tetanus toxoid | None | Sodium chloride, Sodium acetate | None | Formaldehyde |
| Menveo | Polysaccharide coatings from meningococcus A, C, W, Y linked to a detoxified diphtheria protein | None | None | None | Formaldehyde |
*Information from package insert dated: 9/2024 (MenQuadfi); no date (Menveo)
Meningococcal B vaccines
| Vaccine name* | Antigen | Adjuvant | Stabilizers | Preservatives | Residual byproducts |
|---|---|---|---|---|---|
| Bexsero | Proteins and polysaccharide coating from meningococcal B (proteins: Neisserial adhesin A (NadA), Neisserial Heparin Binding Antigen (NHBA), factor H binding protein (fHbp) and polysaccharide coating: Outer Membrane Vesicles (OMV)) | Aluminum hydroxide | Sodium chloride, Histidine, Sucrose | None | Kanamycin |
| Trumenba | Proteins from meningococcal B (factor H binding protein (fHbp) from two subfamilies [A, B]) | Aluminum phosphate | Polysorbate 80, Histidine buffered saline | None | None |
*Information from package insert dated: 8/2024 (Bexsero); 6/2024 (Trumenba)
Meningococcal ABCWY vaccines
| Vaccine name* | Antigen | Adjuvant | Stabilizers | Preservatives | Residual byproducts |
|---|---|---|---|---|---|
| Penbraya | Polysaccharide coatings from meningococcus A, C, W, Y linked to tetanus toxoid AND Proteins from meningococcal B (factor H binding protein (fHbp) from two subfamilies [A, B]) | Aluminum phosphate | Trometamol, Sucrose, Polysorbate 80, L-histidine, Sodium chloride | None | None |
*Information from package insert dated: 9/2024 (Penbraya)
Reviewed by Paul A. Offit, MD, on October 7, 2024