Ingredients in Pneumococcal Vaccines
This page shows the ingredients in pneumococcal vaccines currently available for use in the U.S.
Find out more about pneumococcus and the vaccines that protect against them.
Conjugated pneumococcal vaccines
Vaccine name* | Antigen | Adjuvant | Stabilizers | Preservatives | Residual byproducts |
---|---|---|---|---|---|
Capvaxive (PCV21) | Polysaccharide coatings from pneumococcus serotypes 3, 6A, 7F, 8, 9N, 10A, 11A, 12F, 15A, 15B, 16F, 17F, 19A, 20A, 22F, 23A, 23B, 24F, 31, 33F, and 35B linked to an unharmful diphtheria toxin protein | None | Histidine, Polysorbate 20, Sodium chloride | None | None |
Prevnar 13 | Polysaccharide coatings from pneumococcus serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F linked to an unharmful diphtheria toxin protein | Aluminum phosphate | Polysorbate 80, Succinate buffer | None | None |
Prevnar 20 | Polysaccharide coatings from pneumococcus serotypes 1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F, and 33F linked to an unharmful diphtheria toxin protein | Aluminum phosphate | Polysorbate 80, Succinate buffer, Sodium chloride | None | None |
Vaxneuvance (PCV15) | Polysaccharide coatings from pneumococcus serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F, and 33F linked to an unharmful diphtheria toxin protein | Aluminum phosphate | L-histidine, Polysorbate 20, Sodium chloride | None | None |
*Information from package insert dated: 6/2024 (Capvaxive (PCV21); 8/2017 (Prevnar 13); no date (Prevnar 20), Vaxneuvance (PCV15))
Polysaccharide pneumococcal vaccines
Vaccine name* | Antigen | Adjuvant | Stabilizers | Preservatives | Residual byproducts |
---|---|---|---|---|---|
Pneumovax 23 | Polysaccharide coatings from pneumococcus types 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, and 33F | None | Isotonic saline solution | Phenol | None |
*Information from package insert dated: 4/2021 (Pneumovax 23)
Reviewed by Paul A. Offit, MD, on October 7, 2024