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Ingredients in Pneumococcal Vaccines

Ingredients in Pneumococcal Vaccines

This page shows the ingredients in pneumococcal vaccines currently available for use in the U.S.

Find out more about pneumococcus and the vaccines that protect against them. 

Conjugated pneumococcal vaccines

Vaccine name*AntigenAdjuvantStabilizersPreservativesResidual byproducts
Capvaxive (PCV21)
 
Polysaccharide coatings from pneumococcus serotypes 3, 6A,
7F, 8, 9N, 10A, 11A, 12F, 15A, 15B, 16F, 17F, 19A, 20A, 22F, 23A, 23B, 24F, 31, 33F, and 35B linked to an unharmful diphtheria toxin protein
NoneHistidine, Polysorbate 20, Sodium chlorideNoneNone
Prevnar 13Polysaccharide coatings from pneumococcus serotypes 1, 3,
4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F linked to an unharmful diphtheria toxin protein
Aluminum phosphatePolysorbate 80, Succinate bufferNoneNone
Prevnar 20Polysaccharide coatings from pneumococcus serotypes 1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F, and 33F linked to an unharmful diphtheria toxin proteinAluminum phosphatePolysorbate 80, Succinate buffer, Sodium chlorideNoneNone
Vaxneuvance (PCV15)Polysaccharide coatings from pneumococcus serotypes  1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F, and 33F linked to an unharmful diphtheria toxin proteinAluminum phosphateL-histidine, Polysorbate 20, Sodium chlorideNoneNone

*Information from package insert dated: 6/2024 (Capvaxive (PCV21); 8/2017 (Prevnar 13); no date (Prevnar 20), Vaxneuvance (PCV15))

 

Polysaccharide pneumococcal vaccines

Vaccine name*AntigenAdjuvantStabilizersPreservativesResidual byproducts
Pneumovax 23
 
Polysaccharide coatings from pneumococcus types 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V,
10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, and 33F
NoneIsotonic saline solutionPhenolNone

*Information from package insert dated: 4/2021 (Pneumovax 23)

 

Reviewed by Paul A. Offit, MD, on October 7, 2024

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