This research is studying a vaccine against Mpox (formerly known as monkeypox) that is FDA approved for adults but not yet approved for children. The goal of the study is to determine if the vaccine protects children just as well as it protects adults. The study is also looking at the safety of the vaccine. This study is open to healthy adolescents, ages 12-17. In addition, adolescents with certain immunodeficiency diseases or other conditions, that are well controlled, are eligible to participate.

The Children's Hospital of Philadelphia is recruiting teen drivers to participate in a study that is testing different types of driver training program for reducing new driver crash risk. This study is open to teens between the ages of 16-17 years old who already have an active Pennsylvania learner permit.

Although we know a lot about returning to sports, exercise, and school after concussion, we know very little about returning to drive after a concussion. Our Driving after Concussion study needs the help of both healthy and recently concussed teen partners in our research to understand how concussion affects driving behaviors in teens.We are looking for healthy (have not had a concussion in the last year) and recently concussed teens who are 16.5-18 years old with a drivers license and their own smartphone.Our teen research partners may be asked to complete surveys about themselves and download smartphone applications that track symptoms associated with concussion and/or observe real-world driving behaviors. They may also be asked to come to CHOP's Driving Simulator Lab to complete a 3-hour session that includes surveys, clinical testing, and device testing along with a simulated driving assessment to observe driving behavior.All teens who participate will be compensated for their time and effort.

We are looking for adolescents who have a current diagnosis of anorexia nervosa or other specified feeding and eating disorder and one parent to participate in a study to help us understand higher order thinking differences in teens with eating disorders. We are also looking for adolescents who do not have an eating disorder. The purpose of this study is to look for associations between higher order thinking and eating disorders. These findings may help us understand the impact of eating disorders on thinking skills.

This study wants to know about the problems that Black or African American teenagers with type 1 diabetes (T1D) and their families face. It also wants to see how these problems affect their feelings, behavior, and how they get along with others. The study will find out how well they can handle T1D and adapt to it. It will also learn how good things like being strong, family, and where they live might help young people who have to deal with hard things. This includes how well they handle their feelings, behavior, relationships, and T1D care.