Research Studies Finder

Use this finder to find a study or trial that is the right fit for your child. Also, filter results by phase — which are the specific steps researchers take throughout the trial to find answers, solutions and cures.

Find a recruiting clinical research study

Filter By

Eligible age

Clear selections

Showing 1 - 10 of 349 results

Lutathera in Somatostatin Neuroendocrine Tumors

This study involves taking a study drug called Lutathera.The overall goal of this study is to see if Lutathera is safe in adolescentsubjects with either a gastroenteropancreatic neuroendocrine tumor (GEP-NET),or a pheochromocytoma and/or paraganglioma (PPGL). This study will also look atthe levels of radioactivity after Lutathera administration.

Phase: Phase II

Actively recruiting: Yes

Category: Children

Repotrectinib for ALK, ROS1, or NTRK1-3 Alterations

The purpose of this study is to test the safety and efficacy of the investigational drug called repotrectinib in children whose cancers have specific genetic changes (in the ALK, ROS1, or NTRK1-3 genes). This is the first study using this drug in children under 12 years of age. Repotrectinib is administered in capsule form or liquid suspension.

Phase: Phase I, Phase II

Actively recruiting: Yes

Category: Adults, Children

Conditions: Central Nervous System (CNS) Germ Cell Tumors

FIT4KiD

The purpose of this NIH-funded placebo-controlled clinical trial is to determine how well ferric citrate will lower FGF23, correct anemia and iron levels in the blood, and maintain normal levels of phosphate in children with CKD. Chronic Kidney Disease (CKD) is a condition in which the kidney function is decreased. Fibroblast Growth Factor 23 (FGF23) is a hormone that regulates blood phosphate levels. High FGF23 levels are linked with worsening of kidney, bone & heart health. Ferric Citrate is an oral medication that decreases the absorption of dietary phosphate by the gut, lowers FGF23 levels and raises iron stores in the body. Ferric Citrate is approved in adults with CKD but has not yet been studied in children.
For more information visit www.fit4kidstudy.com

Phase: Phase II

Actively recruiting: Yes

Category: Children

Assessing Optically Pumped Magnetoencephalography (MEG)

The goal for this study is to compare performance between a conventional helium based “Cryo_MEG” (magnetoencephalography) system and an investigational optically pumped (‘OP_MEG’) MEG system using brain recordings from typically developing adults. MEG (magnetoencephalography) is a safe, non-invasive brain imaging method used in many forms of research as well as clinical care. MEG is measured by safely wearing a helmet filled with MEG sensors. During the MEG scan, you will be asked to look at a screen, listen to some tones, and push a button. OPM (Optically Pumped Magnetometry), is a brain imaging method that is also worn as a helmet and acquires MEG recording data but differs from conventional “cryo-MEG” because OPM sensors can be positioned closer to the head. This may present an opportunity for better measurement of underlying brain activity.

Phase: Phase I

Actively recruiting: Yes

Category: Adults, Healthy Controls, MRI/Imaging Studies, One-Time Visit Studies

CHOP-ALS20 Lentiviral gene Therapy for Beta Thalassemia

This clinical trial aims to test a new gene therapy in adults (18 to 35 years old) with beta thalassemia who require regular red cell transfusions. The study will evaluate the safety and efficacy of genetically engineered blood stem cells using a novel lentiviral vector that produces a high levels of a healthy beta globin. Several tests and procedures such as review of medical history, blood and urine tests, bone marrow aspirate/biopsy, heart ultrasound, electrocardiogram, magnetic resonance imaging (MRI) of the heart and liver, and lung tests will be done to find out if subjects are eligible to participate in this trial. If eligible, blood stem cells will be collected by apheresis. These stem cells will then have a healthy beta globin gene inserted. Subjects will then be hospitalized, and chemotherapy will be given to empty out the bone marrow. The stem cells, with the inserted gene (CHOP-ALS20), will then be given back to the subject. Subjects will be followed for side effects and to see if the inserted gene helps make hemoglobin and reduce or stop blood transfusions.

Phase: Phase I, Phase II

Actively recruiting: Yes

Category: Adults

Neuroscience Center Biorepository

In order to understand the conditions that affect the children cared for in the Division of Neurology, we need to better understand underlying mechanisms. This study will enable us to understand how the brain and nervous system work. The goal of this study is to collect biological samples and medical information from children to create a Neuroscience Biorepository to advance future neurological research. Any patient with a neurological condition can participate. Please talk to your provider (Nurse Practitioner or Doctor) about opportunities for your children or their friends to help.

Phase: N/A

Actively recruiting: Yes

Category: Adults, Children, Healthy Controls, One-Time Visit Studies

Defining Clinically Meaningful Outcome Measures For Children With Axial Juvenile Spondyloarthritis

The purpose of this study is to find out how well surveys can measure disease activity in kids with lower back arthritis.The study will last for either 3 or 6 months and take 2 or 3 visits. Each visit will last between 30 minutes and 2 hours and have either an MRI plus a survey or just a survey.

Phase: N/A

Actively recruiting: Yes

Category: Children

Synovial Sarcoma Registry/Biospecimen Repository

The Synovial Sarcoma Registry and Biospecimen Repository was opened in June of 2023 with the goal of furthering research and improving outcomes for patients with synovial sarcoma. This study is open to anyone treated in the United States. You do NOT have to travel to Philadelphia to participate.

Actively recruiting: Yes

Category: Adults, Children

Conditions: Soft tissue sarcomas

VOCAL Trial

This is a study to measure the effectiveness of the medication voclosporin compared to placebo in adolescent patients with active lupus nephritis. Volcosporin is an outpatient, oral medication.

Phase: Phase III

Actively recruiting: Yes

Category: Children

Multimodal Imaging in Autism

The purpose of this study is to understand how children’s brains process sounds and language. Children with Autism Spectrum Disorder (ASD), Intellectual and Developmental Delay (IDD), or Developmental Language Disorder (DLD) often have trouble understanding sounds that are too close together compared to Typically Developing Controls (children without ASD, IDD, or DLD). Fast changes in speech can be hard for children. This may be awkward during conversations and difficult in social situations. This research will see if trouble with processing sounds contributes to language difficulties in children with ASD, IDD, and/or DLD.

Phase: N/A

Actively recruiting: Yes

Category: Children, Healthy Controls, MRI/Imaging Studies

Find a research study

Innovation and your child

Find research studies