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Research Studies Finder

Research Studies Finder

Use this finder to find a study or trial that is the right fit for your child. Also, filter results by phase — which are the specific steps researchers take throughout the trial to find answers, solutions and cures.

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Showing 1 - 10 of 365 results

Harmony TPV

The Harmony Valve study is for patients in need of pulmonary valve replacement. The HarmonyTM Valve is a transcatheter pulmonary valve specifically designed for patients in need of a pulmonary valve replacement who do not want to have to undergo surgery. Surgical placement of a new valve is the most common treatment for a nonworking pulmonary valve, however, there are many risks associated with open heart surgery and it is followed by months of recovery. A less invasive approach for treatment is now available by placement of a pulmonary valve by a transcatheter procedure. The HarmonyTM Valve has not been approved by the FDA yet for commercial use and is only available by participating in the study., Please contact Dr. Matthew Gillespie (gillespie@email.chop.edu) if you or your patient may be interested in participating in the trial of this device.,

Phase: N/A

Actively recruiting: No

Category: Adults, Children

Bio Repository

The purpose of this research study is to collect different types of samples (such as stool, swabs, urine) to form a biorepository. This repository will provide valuable samples from people with and without IBD so that investigators can learn more about the cause of IBD, and different therapies that could be used to treat it. These samples will be used for future gastrointestinal research. Because technology and scientific understanding may advance quickly, it is not yet known what specific studies the samples may be used for.

Phase: N/A

Actively recruiting: Yes

Category: Adults, Children, Healthy Controls

PAIR

The purpose of this study is to characterize the microbiome in children with Crohns disease who have perianal fistula and to compare it to other children with Crohns disease who do not have perianal disease. Studying the role of the microbiome in perianal fistula may help us to develop new therapies.

Phase: N/A

Actively recruiting: No

Category: Adults, Children

The Bladder Brain Connection - Why Are Some Children Wet?

We know very little about how the bladder to brain connections work in children. The most common thing we hear from children who are having urinary leakage is "I was not aware my bladder was full." Is this full bladder message getting lost? In this study we will measure brain wave activity non invasively after you have drank some Gatorade to get a full bladder and after you have voided. The total time needed for this study will be about 3 to 4 hours.

Phase: N/A

Actively recruiting: No

Category: Adults, Children, MRI/Imaging Studies, One-Time Visit Studies

Phase II Mayo Clinic Stem Cell Trial for HLHS

The purpose of this research study is to find out if stem cells from umbilical cord blood (collected at birth) can strengthen the muscle of the right side of the heart for patients diagnosed with Hypolplastic Left Heart Syndrome who are scheduled to undergo the Stage II Glenn surgical procedure.

Phase: Phase II

Actively recruiting: No

Category: Children

FLG Mutations and Atopic Dermatitis

The primary objective is to confirm the association of theFilament-Aggregating Proteinloss-of-function mutations with respect to the severity of disease (its persistence) and its association with components of the atopic triad (i.e., seasonal allergy and asthma) within ourAtopic Dermatitiscohort.

Phase: N/A

Actively recruiting: Yes

Category: Adults, Children

CPSMC Pilot Study

The purpose of this study is to assess deficits in movement and coordination in children with cerebral palsy (CP) and without. Children with CP have trouble coordinating their muscles while moving. Few options exist to measure muscle control. This new test will measure muscle control in children with and without CP and help guide future treatment plans.

Phase: N/A

Actively recruiting: Yes

Category: Children

Omics Study For CDG Patient

This is an intergrated study of patients with congenital glycosylation disorder, including genetic conditions in the synthesis of glycoconjugates (congenital disorder of glycosyaltion), degradation of glycoconjugates (majority of lysosomal storage conditions), as well as the metabolism of glycoconjugates (such as certain inborn errors of metabolism that involved in nucleitide sugar metabolism, such as galactosemia, fructose intolarance, or certain glycogen storage conditions). Study methods includes glycomics analysis of body fluid or cells or tissues from patients, relevant metabolomics and genomics analysis.

Phase: N/A

Actively recruiting: Yes

Category: Adults, Children

Tofa For UC

The purpose of this research study is to help us understand how well tofacitinib works as a treatment for ulcerative colitis or indeterminate colitis in pediatric patients. We are looking to enroll, males or females ages 6 to 21 years old with a diagnosis of ulcerative colitis or indeterminate colitis who have started tofacitinib therapy prescribed by their primary gastroenterologist within the past 2 weeks or will be starting tofafacitinib within 1 month.

Phase: N/A

Actively recruiting: Yes

Category: Adults, Children, Remote (Online / Phone Call Only) Studies

Fontan Liver MRE

Patients with who have had Fontan surgery are at risk for the development of liver fibrosis and cirrhosis. New MRI based imaging techniques allow for non-invasive assessment of liver stiffness and fibrosis. These methods have been used in other diseases, but have not been studied in those who have undergone the Fontan operation. In this study we will test the feasibility of MRI based methods for the assessment of liver disease, and compare the results of these studies to those obtained from clinical liver biopsy.

Phase: N/A

Actively recruiting: No

Category: Adults, MRI/Imaging Studies

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