Researchers from Children’s Hospital of Philadelphia (CHOP) collaborated with other health systems to develop specialized growth charts for children with Beckwith–Wiedemann Spectrum (BWSp), the most common epigenetic overgrowth and cancer predisposition disorder in children. The findings illustrate how newly developed growth charts are designed to better represent how children with the condition grow, which can improve personalized treatment.

New research from Children’s Hospital of Philadelphia (CHOP) offers insight into how a rare genetic condition called Beckwith–Wiedemann syndrome (BWS) affects the liver and may raise cancer risk.

Parents are usually blindsided when they find out that their child has congenital hyperinsulinism (HI), a rare genetic disorder that depresses blood sugar to dangerously low levels.

New Cell Models Help Researchers Study Disease Development and Growth Issues in Beckwith-Wiedemann Syndrome