The Difference Between Dominant and Recessive Gene Mutations
Published on in HI Hope

Congenital hyperinsulinism (HI) is often passed from parent to child through a gene variant. Here’s how dominant and recessive gene variants work.
Published on in HI Hope
Congenital hyperinsulinism (HI) is often passed from parent to child through a gene variant. Here’s how dominant and recessive gene variants work.
Published on in CHOP News
Read this case study about integrating precision medicine into the standard of care for children with thyroid cancer.
Published on in CHOP News
When radioactive iodine is spared, there is no decrease in the likelihood of remission.
Published on in Health Tip of the Week
New cases of type 2 diabetes, when the body can’t use or make enough insulin, soared in kids during the COVID-19 pandemic. Learn the signs and how CHOP can help!
Published on in CHOP News
CHOP researchers have used advanced 3D mapping techniques to identify genetic variants and corresponding target genes in the pancreas that are implicated in type 2 diabetes.
Published on in HI Hope
Many children with hyperinsulinism (HI) have feeding aversion — as many as 60%. The use of tube feedings, and possibly continuous dextrose, to control their blood sugar, among other things (effect of medications, the appetite suppressing effects of insulin, etc.), may exacerbate their aversion to eating by mouth.
Published on in HI Hope
If Leela Morrow, PsyD, the psychologist for the Congenital Hyperinsulinism Center at Children’s Hospital of Philadelphia, gives your child a referral for a neuropsychology evaluation it’s nothing to be afraid of. In fact, it may give your child a roadmap to success.
Published on in HI Hope
Much progress has been made over the last 25 years when it comes to identifying the genetic mutation that is causing a child’s congenital hyperinsulinism (HI).
Published on in CHOP News
Unique endocrinology-neurology collaboration seeks to understand the variation in seizure activity in patients with hyperinsulinism/hyperammonemia.
Published on in CHOP News
CHOP researchers have shown that a targeted treatment they developed is effective at controlling blood sugar in patients with hyperinsulinism.