Published on in CHOP News
Aberrant splicing leads to downregulation of CD22 in pediatric B-ALL, rendering malignant cells resistant to the effects of CD22-directed immunotherapies.
Published on in CHOP News
CHOP researchers have found no detectable levels of double-stranded RNA during adenovirus infection, upending previous assumptions about infection by the virus.
Published on in CHOP News
Their projects will focus on different aspects of gene expression, from developing new imaging tools to searching for causes of cancer.
Published on in CHOP News
Dr. Stephen R. Master will serve as president of the American Association for Clinical Chemistry until July 2022.
Published on in CHOP News
Type II alveolar cells, a major cell type infected by SARS-CoV-2, possess unique immunologic properties and appear to play a role in improving the outcome of respiratory viral infections.
Published on in CHOP News
Using a novel proteomics approach, CHOP researchers have identified a host protein that restricts herpes simplex virus 1 (HSV-1) infection.
Published on in CHOP News
CHOP researchers have developed a sequencing method to detect RNA modifications that regulate RNA splicing during adenovirus infection.
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In a study published in Nature Microbiology, CHOP researchers uncover a ubiquitination mechanism that helps adenovirus replicate efficiently in host cells.
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Using a powerful new tool to massively sequence genetic code in heart cells may lead to more precise treatments for heart disease.
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A CHOP scientist advocates providing automated updates to clinical genetics tests to account for new knowledge that may benefit patients and families.