Research Studies and Clinical Trials
The CVAP was designed and implemented in response to the need for a well-coordinated multi-disciplinary clinic and research program. This allows providers to collaborate more effectively in serving patients and their families.
The research component revolves around findings that certain genetic mutations are the root cause of many vascular anomalies, some of which are responsive to advanced therapies that are not yet clinically indicated treatments for these conditions. Conducting clinical trials to help find promising treatments for patients with vascular anomalies will hopefully lead to U.S. Food and Drug Administration approval of these much-needed treatments. As a result, in the future countless more patients will benefit from this life-saving precision medicine approach. CHOP has been at the forefront of discovery of precision medicine in several of these disorders and has the ability to continue excellent clinical, translational and basic science research to further these discoveries.
Surveillance Epidemiology of Coronavirus (COVID-19) Under Research Exclusion
The SECURE-VA registry was created to capture important information about pediatric and adult COVID-19 cases that are occurring across the world in patients living with vascular anomalies. The goal of this voluntary reporting system is to better understand outcomes of COVID-19 cases in this population of patients.
Consortium of iNvestigators of Vascular AnomalieS (CaNVAS)
The Consortium of iNvestigators of Vascular AnomalieS (CaNVAS) is a multi-institutional research consortium founded by a group of pediatric hematologist/oncologists and patient advocacy groups to address the rare nature of vascular anomalies. The need for this consortium stems from the rare nature of these disorders and the paucity of prospective multicentered research in this field, particularly as it relates to novel therapies and outcome studies.
CaNVAS is organized to foster the diffusion and exchange of ideas through scientific meetings, research trials and publications.