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Aplastic Anemia — Laboratory Evaluation — Clinical Pathway

Aplastic Anemia Clinical Pathway — All Settings

Laboratory Evaluation

Initial Management in First Encounter

Peripheral Blood (Initial Mgmt by Any Provider)
  • CBC w/ Diff, Reticulocyte count
    • Order in EPIC: BLOOD SMEAR, MD Interpretation and Report
  • CMP, LDH, Uric Acid
  • PT, PTT, INR
  • UA
  • Pregnancy test
    • Post-pubertal and/or greater than 12 years age
  • Blood culture if febrile

Perform only after consultation with BMF Team (To be sent within 5 days of admission)

Genetic Testing
  • Required Inherited BMF Testing (To be sent within 5 days of admission)
  • Chromosomal breakage studies
    • Send to Dana Farber; Mon-Thurs only
  • Telomere length analysis to Repeat Diagnostics
    • "Send out to Repeat Diagnostics, Vancouver Canada”
  • HLA Typing
  • HLA typing is optimally done in inpatient setting
  • BMF Team will coordinate testing with BMT Coordinator

If these studies are done in an outpatient setting, assure insurance approval.

 

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