Central Diabetes Insipidus (DI)/Arginine Vasopressin Deficiency (AVP-D) Clinical Pathway – PICU
Central Diabetes Insipidus (DI)/Arginine Vasopressin Deficiency (AVP-D) Clinical Pathway – PICU
Free Water Replacement
- Free water replacement may be needed to correct hypernatremia
- Replace fluid deficit using the following recommendations:
- Replacement is typically given over 24 hrs but will depend on the degree of deficit and hypernatremia, as well as duration of hypernatremia
- If Na remains above goal after free water replacement, reassess
Typical Fluid Choices |
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Calculation for Fluid Replacement Volume | 0.6 x weight (kg) x (1-target Na/current Na) |
Max Na Change | 10-12 mEq/L/24 hrs |