Active COVID-19 Clinical Pathway – All Settings

Clinical Pathway for Evaluation and Treatment of
Child with Acute COVID-19 Infection

Provider Resources
Patient Education

Child with Acute COVID-19 Infection

(+) SARS-CoV-2 PCR or antigen test and clinical symptoms
 
 

Team Assessment

History and Physical

Initiate isolation precautions
 
 
Determine Severity of Illness
 
 
 
 

Mild/Moderate

  • Fever, fatigue, myalgia
  • Nasal congestion, sore throat
  • Cough
  • Tachypnea without supplemental O2 requirement or pneumonia

Severe

Hypoxemia requiring supplemental O2 requirement via nasal cannula

Critical

  • Hypoxemia or respiratory distress requiring high-flow nasal cannula, non-invasive positive pressure ventilation, mechanical ventilation, or ECMO
  • Septic shock
 
 
 
 
 
 

Consider labs/imaging

Assess presence of high-risk conditions
Labs/Imaging
 
 
 
 
 
 
No High-Risk Condition
High-Risk Condition
Admit to inpatient or PICU special treatment room
Treatment recommendations by illness severity
 
 
 
 
 
 
Child ≥ 12 yrs old
and
≥ 40 kg
Child < 12 yrs old
or
< 40 kg
 
 
 
 

Discharge

Supportive care
  • Discharge
  • Supportive care
  • Consider remdesivir with subspecialty service