Clinical Pathway for Evaluation and Treatment of Patients
with Active COVID-19 Infection

  • History & Physical Exam
    • Symptoms, Exposure
    • Consider MIS-C
    • Initiate Isolation Precuations
  • Fever, sore throat, cough
  • Myalgias
  • No respiratory distress
  • No O2 requirement
  • Adequate hydration
  • New O2 requirement
    • Not rapidly escalating
    • Not requiring CPAP, BiPap, or intubation
  • Escalation in baseline respiratory support, PICU not required
  • Hypoxia or respiratory distress requiring
    • Invasive or non-invasive ventilation
  • SIRS/sepsis/multisystem organ failure
  • Escalation in baseline
    • Invasive or non-invasive ventilation requiring PICU admission
  • Rapidly deteriorating clinical condition that does not yet meet these criteria
Supportive Care, Discharge
Admit to Special Treatment Room for COVID-positive patients
Admit to PICU Special Treatment Room
Posted: June 2020
Revised: June 2020, July 2020, August 2020, September 2020, November 2020, February 2021, March 2021, June, 2021,
September 2021
Authors: K. Chiotos, MD; D. Davis, MD; C. Kerman, MD; J. Gerber, MD; J. Lavelle, MD