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Double Volume Exchange Transfusion Clinical Pathway, ICU – Lab Schedule

Double Volume Exchange Transfusion Clinical Pathway — ICU

Lab Schedule

Order all labs to be drawn during the procedure before starting.

Start of exchange optional labs: Discuss if any of these tests should be sent as results will be affected by the exchange if not sent prior to starting.

Lab Schedule During Exchange Transfusion

Timeframe Volume Labs Optional
Pre-Procedural 6.9 mL
  • CBC
  • Type and Screen
  • Blood type confirmation
  • Retic count
  • Bilirubin
  • Albumin
  • DNA Extraction
 
Start of Exchange 2.5 mL
2 mL without
NB screen
  • CBC
  • BMP
  • Blood gas with ionized calcium
  • Newborn Metabolic Screen if
    not completed
  • Retic count
  • Bilirubin
  • Genetic/metabolic studies, including DNA extraction if not already sent
  • Infectious labs
  • Hemoglobin electrophoresis
  • Red cell enzyme studies
Every 15 mins 0.2 mL Glucose If clinically unstable, blood gas with ionized calcium
Every 30 mins 1 mL Blood gas with ionized calcium  
At 60 mins 0.5 mL  
  • Platelet level
  • Consider sending for premature infants or low at onset
End of Exchange 2 mL
  • CBC
  • BMP
  • Bilirubin
  • Albumin
  • Glucose
  • Blood gas with ionized calcium
 
30 min Post-Exchange 0.2 mL Glucose  
60 min Post-Exchange 0.2 mL Glucose  
4 hrs Post-Exchange 1 mL
  • CBC
  • BMP
  • Bilirubin
 

 

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