Clinical Pathway for Evaluation and Treatment of Oncology Patients at Risk for Tumor Lysis Syndrome (TLS)


  • Reduce the incidence of fluid overload and of renal insufficiency, hyperkalemia, hypophosphatemia and hypocalcemia in these patients
  • Reduce the inappropriate overuse of laboratory tests including chemistries and blood counts


  • % patients needing dialysis
  • % patients transferred to higher level care
  • % of patients that require increased respiratory support
  • Incidence of seizures
  • Measure use of pertinent laboratory studies