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Mpox — Differential Diagnosis — Clinical Pathway: Emergency Department, Outpatient Specialty Care and Primary Care

Mpox (Monkeypox) Clinical Pathway — Emergency Department, Outpatient Specialty Care and Primary Care

Differential Diagnosis for Mpox

Possible Case of Monkey pox requires: Exposure and Rash + Rash

Exposure Type

STI
  • HSV
  • Syphilis
  • Disseminated Gonorrhea
  • Chancroid
  • Lymphogranuloma Venereum (LGV)
  • Consult STI Pathway for diagnosis and management
Viral Rashes
  • Varicella
  • Enterovirus
    • Coxsackievirus
    • Hand, foot, and mouth disease
  • Measles
  • Molluscum contagiosum
Bacterial
  • Bacterial Impetigo
    • Bullous and non-bullous
Allergic
  • Contact dermatitis
  • Atopic dermatitis with superinfection
  • Drug eruption

Additional Guidance

Mpox 101: What Clinicians Need to Know

 

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