Neonatal Myelomeningocele/Myeloschisis Clinical Pathway — ICU
Neonatal Myelomeningocele/Myeloschisis Clinical Pathway — ICU
Antibiotic Recommendations for Infants in the N/IICU with Myelomeningocele/Myeloschisis
General Principles
- Antibiotic goal administration time is within 1 hour of delivery in the SDU.
- For infants with suspected sepsis, see the N/IICU sepsis pathway for antibiotic recommendations following fetal surgery.
- Consider ID consult for infants with suspected infections.
- UTI prophylaxis should be started at birth for infants not receiving broad-spectrum antibiotics for another reason. For patients receiving broad-spectrum antibiotics pre-operatively or for suspected sepsis, these broad-spectrum antibiotics provide adequate coverage for UTI prophylaxis.
- UTI prophylaxis may be discontinued if a renal/bladder ultrasound is normal and the infant does not require clean intermittent catheterization, in discussion with urology.
Postnatal Closure
Broad-spectrum Antibiotics Immediately Following Delivery |
Antibiotics for UTI Prophylaxis | |
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Open Defects |
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Closed/Skin Covered Defects (e.g., Lipomyelomeningocele) |
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See the CHOP Formulary for complete drug information.