Inhaled Nitric Oxide for Acute Hypoxemic Respiratory Failure Clinical Pathway — PICU
Inhaled Nitric Oxide for Acute Hypoxemic Respiratory Failure Clinical Pathway — PICU
Clinical Indicators that that may alter weaning of iNO
Clinical Indicator | Rationale | Comments |
---|---|---|
Elevated Brain Natriuretic Peptide (BNP) compared to baseline if available or within laboratory limits | If consistent with prior values or within available limits, BNP should not prevent weaning for true refractory hypoxemic respiratory failure. |
|
< 40% FiO2 | iNO can be weaned more quickly if FiO2 is below this value | |
High Frequency Oscillatory Ventilation (HFOV), High Frequency Percussive Ventilation (HFPV/VDR) | Does not preclude weaning of iNO | If on HFPV/VDR, iNO can be weaned but the lower dose (ppm) increments will be dependent on the patient’s settings. |