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Partial Volume Exchange Transfusion — Indications — Clinical Pathway: ICU

Partial Volume Exchange Transfusion, Clinical Pathway, ICU

Indications for a Partial Volume Exchange Transfusion in Neonates

This pathway should be used to guide the management of infants requiring a PVET using the following criteria:

  • Symptomatic anemia with euvolemia and/or cardiac dysfunction
  • Symptomatic polycythemia hyperviscosity syndrome
  • Asymptomatic polycythemia with hematocrit > 75%
  • PVETs should only be performed in the NICU/CICU/PICU

Exclusions

Defining Partial Volume Exchange Transfusion

  • Procedure that introduces donor blood or other fluids in exchange for variable percentage of circulating blood volume depending on degree of anemia/polycythemia
  • The infant’s blood is repeatedly withdrawn in small amounts and replaced with equal amounts of donor blood/other fluids
  • Purpose is to correct extremes of hematocrit while maintaining and/or achieving euvolemia

 

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