Open Long Bone Fracture Clinical Pathway — Emergency Department
|Fracture Type||First-line Antibiotics||Second-line Antibiotics
For severe penicillin or
|I or II||
|III A,B, or C||
- Assess the nature of the penicillin allergy per the Clinical Pathway for the Assessment of Children with a Penicillin Drug Allergy. Patients with non-severe penicillin allergies (including hives) can receive cefazolin. Severe penicillin allergy includes any of the following: anaphylaxis, angioedema, cardiac arrest, respiratory distress, severe cutaneous reaction (for example, Stevens Johnson syndrome, erythema multiforme, DRESS and TEN). All other reactions considered non-severe and should receive the recommended antibiotic.