Newborn Persistent Hypoglycemia Clinical Pathway — N/IICU
Newborn Persistent Hypoglycemia Clinical Pathway — N/IICU
Critical Fasting Labs
The following chart refers to tests done at CHOP; confirm with your lab before drawing samples and for interpretation of normal values.
| Blood Test | MINIMUM amount of whole blood required and Collection Tube | Normal Values in setting of Glucose < 50 | |
|---|---|---|---|
| Critical Fasting Labs These are required labs and should be drawn when glucose < 50 |
Plasma Lactate (critical) | 0.5 ml Light green microcontainer on ice - do not use a tourniquet |
0.6-2 mmol/L |
| Plasma insulin level (critical) | 1 ml Gold serum separator tube (glass) |
< 2 uU/mL | |
| Bicarbonate | Included with CMP | 15-20 mmol/L | |
|
CMP |
0.8 mL Light green microtainer |
Routine normals | |
| > 2 mmol/L | |||
| Helpful Labs Good to obtain if able |
Free Fatty Acids | 1 mL Gold serum separator tube |
> 2 mmol/L |
| Growth Hormone C-Peptide Cortisol |
1.5 mL Gold serum separator tube (glass) |
> 7 ng/ml | |
| < 0.5 ng/mL | |||
| > 10 mcg/dL | |||
| Ammonia |
|
< 33 umol/L | |
| Acyl-carnitine profile, total and free carnitine | 2.0 ml Green (sodium heparin) |
Routine normals | |
| Urine Organic Acids | 5 mL urine in sterile container | Routine normals | |
| Additional Tests Depending on suspected diagnosis, may consider drawing and holding specimens |
IGFBP-1 (Insulin-like growth factor-binding protein 1) | 1 mL Gold serum separator tube |
> 180 ng/ml |