Craig H. Bassing, PhD Craig H. Bassing, PhD, is an assistant professor and investigator with the Research Institute of The Children's Hospital of Philadelphia. Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467) Education and Training FellowshipResearch Fellow in Molecular Immunology - Irvington Institute for Immunological Research, New York, NY Research Fellow in Molecular Immunology - CBR Institute for Biomedical Research, Boston, MA Research Fellow in Genetics - Harvard Medical School, Boston, MA Research Fellow in Medicine, Boston Children's Hospital, Boston, MA Research Associate in Molecular Immunology - Howard Hughes Medical Institute, Philadelphia, PA Research Fellow in Cancer Genetics - Lymphoma Research Foundation, New York, NY Undergraduate DegreeBA in Biology - The Johns Hopkins University, Baltimore MD Graduate DegreePhD in Biology - Duke University, Durham, NC Titles and Academic Titles InvestigatorAssociate Professor of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine Research Interests Read my profile on the Children's Hospital Research Institute site » Publications Papers2015 Ehlich, L.A., Yang-Iott, K., DeMicco, A., and Bassing, C.H.: Somatic Inactivation of ATM in Hematopoietic Cells Predisposes Mice to Cyclin D3 Dependent T Cell Acute Lymphoblastic Leukemia Cell Cycle 14: 388-98. 2015. 2014 Steinel, N.C., Fisher, M., Yang-Iott, K.S., and Bassing, C.H.: The Ataxia Telangiectasia Mutated and Cyclin D3 Proteins Cooperate to Enforce Tcrb and Igh Allelic Exclusion. Journal of Immunology 193: 2881-2890, 2014. Rupp, L.J., Brady, B.L., Carpenter, A.C., De Obaldia, M.E., Bhandoola, A., Bosselut, R., Muljo, S.A., and Bassing, C.H.: The microRNA biogenesis machinery modulates lineage commitment during αβ T cell development The Journal of Immunology 193: 4032-4042, 2014. Horowitz, J.E. and Bassing, C.H.: NonCore RAG1 Regions Promote Vβ Rearrangements and αβ T Cell Development by Overcoming Inherent Inefficiency of Vβ Recombination Signal Sequences Journal of Immunology 192: 1609-1619. 2014. Ehrlich, L.A., Yang-Iott, K., and Bassing, C.H.: Tcrδ Translocations that Delete the Bcl11b Haploinsufficient Tumor Suppressor Gene Promote Atm-deficient T Cell Acute Lymphoblastic Leukemia Cell Cycle 13: 3076-82, 2014. 2013 Steinel, N.C., Lee, B.-S., Tubbs, A.T., Bednarski, J.J., Schulte, E., Yang-Iott, K.S., Schatz, D.G., Sleckman, B.P., and Bassing, C.H. : The Ataxia Telangiectasia Mutated Kinase Controls Igκ Allelic Exclusion by Inhibiting Secondary Vκ-to-Jκ Rearrangements Journal of Experimental Medicine 210: 233-9, 2013. DeMicco, A., Yang-Iott, K.S., and Bassing, C.H.: Somatic Inactivation of Tp53 in Hematopoietic Stem Cells or Thymocytes Predisposes Mice to Thymic Lymphomas with Clonal Translocations Cell Cycle 12: 3307-16, 2013. Brady, B.L., Rupp, L.J., and Bassing, C.H.: Requirement for Dicer in Survival of Proliferating Thymocytes Experiencing DNA Double Strand Breaks Journal of Immunology 190: 3256-66, 2013. BooksChapters 2000 Shaw, A. C., Bassing, C. H., Swat, W., and Alt, F. W. : Signal transduction and regulation of antigen receptor gene rearrangement during early lymphocyte development. Hematopoiesis: A Developmental Approach. Oxford University Press, Page: 544-564, 2000. 1995 Datto, M. B., Bassing, C. H., and Wang, X.-F. : The TGF-beta receptors and signaling pathways. Growth Factors and Cytokines in Health and Disease. JAI Press, Inc. Page: 395-432, 1995. Posters and PresentationsInvited Lectures 2014 "Molecular Control of Immunoglobulin Gene Rearrangements and B Cell Development", Tri-Institute Immunology Program of Rockefeller University, Cornell Medical School, and Memorial Sloan Kettering Cancer Institute, New York, NY, January 2014. 2013 "ATM inhibits secondary Igk rearrangements to enforce Igk allelic exclusion", New York Academy of Sciences Genomic Integrity Meeting, NY, NY, April 2013. Awards and Honors 2010-present, Leukemia and Lymphoma Society Scholar Award 2010, Pathology and Laboratory Medicine Chair Award of the Children's Hospital of Philadelphia 2009, Michael S. Brown New Investigator Research Award, University of Pennsylvania School of Medicine 2008-2009, Lassin Family Cancer Research Award at the Abramson Cancer Center of the University School of Medicine 2008, American Cancer Society Institutional Research Award 2006-2007, American Cancer Society Institutional Research Award 2005-2009, Pew Scholar in the Biomedical Sciences 2005-2006, Foerderer-Murray Award 2005-2007, W.W. Smith Charitable Trust Award 2005-2006, American Cancer Society Institutional Research Award 2003-2005, Lymphoma Research Foundation Fellow Award 1997-2000, Irvington Institute for Immunological Research Fellow Award 1992, Departmental Honors (Biology), The Johns Hopkins University 1992, University Honors, The Johns Hopkins University 1992, Golden Key Honor Society, The Johns Hopkins University Chapter 1992-1995, National Science Foundation Pre-Doctoral Fellow Award 1991, Howard Hughes Medical Institute, Summer Fellow 1991, Phi Beta Kappa Honor Society, The Johns Hopkins University Chapter 1990, Alpha Epsilon Delta Honor Society, The Johns Hopkins University Chapter Editorial and Academic Positions Editorial Positions 2013-present, The Journal of Immunology, section editor 2012-present, F1000 Research, editorial board 2012-present, American Journal of Clinical and Experimental Immunology, founding editorial board Ad hoc reviewer 2011-present, PLoS ONE 2010-present, Human Molecular Genetics 2010-present, Nature Reviews in Cancer 2010-present, Journal of Cell Biology 2009-present, Molecular and Cellular Biology 2009-present, Oncogene 2008-present, Nucleic Acids Research 2008-present, Journal of Clinical Investigation 2007-present, Science 2007-present, Cell 2006-present, Blood 2006-present, Immunity 2005-present, Nature 2005-present, Journal of Experimental Medicine 2005-present, PNAS 2005-present, Cell Cycle 2005-present, DNA Repair 2005-present, Nature Immunology 2005-present, EMBO Academic and Institutional Committees 2014-present, Cancer Biology Graduate Group, chair 2014-present, CB Executive Committee, chair 2014-present, CAMB Executive Committee 2014-present, CB Preliminary Exam Committee 2014-present, Biomedical Advisory Committee 2014, Penn Institute for Immunology Pilot Grants Review Panel 2014, Radiation Safety Committee of the University of Pennsylvania 2013, Graduate Group in Pharmacology of the University of Pennsylvania, review committee 2012-present, Cell and Molecular Biology Training Grant of the University of Pennsylvania, executive committee 2012-present, CCCR Biobank Scientific Review Council 2012-2014, CB Advising Committee, chair 2011-present, Abramson Family Cancer Research Institute, associate investigator 2010-present, Institute for Immunology 2010-present, IGG Executive Committee 2010-present, Abramson Cancer Center - Pediatric Oncology Research 2010-2015, Selection Committee for the Michael S. Brown New Investigator Research Award 2009-present, IGG Student Affairs Committee, ad hoc member 2009-present, ACC Review Committee for American Cancer Society Pilot and Institutional Grants 2009-2014, CB Advising Committee 2007-present, ACC Review Committee for American Cancer Society Pilot and Institutional Grants 2005-present, IGG Admissions Committee 2004-present, Cell and Molecular Biology Graduate Group - Cancer Biology 2004-present, Immunology Graduate Group Leadership and Memberships Memberships in Professional Organizations International 2012-present, Leukocyte Development Section in the Immunology Faculty 2010-present, The Henry Kunkel Society National 2014-present, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health - Board of Scientific Counselors - Division of Intramural Research 2008-present, American Association for Cancer Research 2005-present, American Association of Immunologists 1992-present, American Association for the Advancement of Science Patient Experience Ratings About the Patient Experience Rating System The Patient Experience Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question. Responses are measured on a scale of 1 to 5 with 5 being the best score. The comments are submitted by patients and families and reflect their views and opinions. The comments are not endorsed by and do not reflect the views of Children’s Hospital of Philadelphia.