George H. Rothblat, PhD

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George H. Rothblat, PhD,  is a researcher with the Division of Gastroenterology, Hepatology and Nutrition at The Children's Hospital of Philadelphia.

Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Undergraduate Degree

BS in Bacteriology - University of Connecticut, Mansfield, CT

Graduate Degree

PhD in Medical Microbiology - University of Pennsylvania, Philadelphia, PA

Titles and Academic Titles

Senior Member, Joseph Stokes Research Institute

Research Professor of Pediatrics, University of Pennsylvania School of Medicine

Publications

Papers

2012

G.L. Weibel, M.R. Joshi, W.G. Jerome, S.R. Bates, K.J. Yu, M.C. Phillips, G.H. Rothblat: "Cytoskeleton disruption in J774 macrophages: consequences for lipid droplet formation and cholesterol flux" Biochim Biophys Acta 1821(3): 464-72, Mar 2012.

R.S. Rosenson, H.B. Brewer, Jr., W.S. Davidson, Z.A. Fayad, V. Fuster, J. Goldstein, M. Hellerstein, X.C. Jiang, M.C. Phillips, D.J. Rader, A.T. Ramaley, G.H. Rothblat, A.R. Tall, L. Yvan-Charvet: "Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport" Circulation 125(15): 1905-19, Apr 17 2012.

W.R. Lagor, D.W. Fields, S.A. Khetarpal, A. Kumaravel, W. Lin, N. Weintraub, K. Wu, S.F. Hamm-Alvarex, D. Drazul-Schrader, M. de la Llera-Moya, G.H. Rothblat, D.J. Rader: "The effects of apolipoprotein F deficiency on high density lipoprotein cholesterol metabolism in mice" PLoS One 7(2): e31616, 2012.

Books

Rothblat GH, Cristofalo VJ: Growth, Nutrition, and Metabolism of Cells in Culture,  (Vol. 1, 2, and 3). G. H. Rothblat and V.J. Cristofalo  (eds.). Academic Press  1997.

Chapters

2010

G. Kellner-Weibel, M. de la Llera-Moya, S. Sankaranarayanan, G.H. Rothblat: "In Vitro Studies and Mass Flux of Cholesterol Between Serum and Macrophages,"  High Density Lipoproteins, Dyslipidemia, and Coronary Heart Disease. E. Schaefer (eds.). Springer, New York, Page: 83-88, 2010.

G. H. Rothblat, M.C. Phillips: "High Density Lipoprotein (HDL) Heterogeneity and Function in Reverse Cholesterol Transport,"  Current Opinion in Lipidology 21(3): 229-238, June 2010.

1998

Phillips MC, Gillotte KL, Haynes MP, Johnson WJ, Lund-Katz S, Rothblat GH: Mechanisms of high density lipoprotein-mediated efflux of cholesterol from cell plasma membranes. Atherosclerosis 137: S13-S17, 1998.

Phillips MC, Gillotte K, Lund-Katz S, Johnson W, Rothblat GR: High-density lipoproteins and cellular cholesterol efflux. Atherosclerosis XI-Proceedings of the XIth International Symposium on Atherosclerosis. B. Jacotot, D. Mathe and J.-C. Fruchart (eds.). Elsevier Science, Singapore, Page: 861-865, 1998.

1995

Rothblat GH, Yancey P, Davidson WS, Atger V, Lund-Katz S, Johnson WJ, de la Llera-Moya M, Phillips MC: Cholesterol efflux from cells in culture: Studies with lipid-free acceptors, reconstituted particles and whole serum. Cardiovascular Disease 2. Cellular and Molecular Mechanisms, Prevention and Treatment. L.L. Gallo (eds.). Plenum Press, New York, Page: 89-96, 1995.

1967

Rothblat, G.H., R. Hartzell, H. Mialhe, and D. Kritchevsk: Cholesterol metabolism in tissue culture cells. Lipid Metabolism in Tissue Culture Cells  G.H. Rothblat and D. Kritchevsky (eds.). Wistar Institute Press, Philadelphia, Page: 129-149,  1967.

Awards and Honors

1989, Pfizer Traveling Fellow
1988, Recipient Johnson & Johnson, Focused Giving Award
1970-1975, Established Investigator, American Heart Association
1966-1969, NIH Special Research Fellowship

Editorial and Academic Positions

Academic and institutional committees

2001-present, Stokes Investigators Committee

Leadership and Memberships

Memberships in professional organizations

1989-present, American Association for the Advancement of Science
1970-present, American Heart Association

  • 1995-present, Fellow, Council on Arteriosclerosis