Clinical Research Finder

Children's Hospital of Philadelphia leads or participates in hundreds of clinical trials. Use this database to learn the purpose of these trials, find out who can participate and more.

Find a Clinical Research Study

131 - 138 of 138

Abatacept Registry

The purpose of this registry is to study the long-term effects and safety of Abatacept(Orencia) as used for the treatment of Juvenile Idiopathic Arthritis(JIA). JIA patients that are currently taking Abatacept may be eligible to participate in this study.

A Randomized, Open-label, Safety and Efficacy Study of Ibrutinib in Pediatric and Young Adult Patients With Relapsed or Refractory Mature B-cell non-Hodgkin Lymphoma

CHOP, in collaboration with the Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) consortium and Janssen Research & Development, is conducting a study for children and young adults up to 30 years old, with relapsed or refractory mature B-cell non-Hodgkin Lymphoma (NHL). This clinical trial is adding the study drug, ibrutinib, to a standard relapse B-cell NHL chemotherapy regimen. For more information about this study, including specific eligibility criteria, please visit clinicaltrials.gov and search for "NCT02703272" or visit the TACL website at https://tacl.chla.usc.edu/Tacl/#!/Page/3. To hear more about this and other available trails or get any questions answered please contact our Cancer Intake Specialist by phone at 267-426-0762 or email Oncointake@email.chop.edu.

POOPS

The purpose of this study is to determine how what you eat and drink (your diet), antibiotics you take, and the bacteria that live in your gut (microbiome) contribute to developing kidney stones. Kidney stone disease, known as nephrolithiasis, is also influenced by products of metabolism (metabolites) that are found in your urine. These factors will be examined in participants at least 4 years of age. Each participant will completed three 24-hour dietary recalls and will provide one stool sample and two urine samples. The information from this study will help doctors find new metabolic pathways that can be used for treatment of kidney stones.

Vitamin E Supplementation in Hyperinsulinism/Hyperammonemia (HI/HA) Syndrome

Our team is working on a study to see if children with HI/HA Syndrome tolerate Vitamin E supplementation. This is an experimental, non-FDA approved use of Vitamin E which will lead to further studies to evaluate if Vitamin E can be used as a treatment for HI/HA. The study involves taking Vitamin E once a day for two weeks at home, completing a tolerability questionnaires, and two, one-day visits to the CHOP outpatient Center for Human Phenomic Science (one visit before and one visit after taking the Vitamin E supplement for two weeks). During each study visit, fasting oral protein tolerance will be performed and blood samples will be drawn. If you're interested in learning more, please contact us at ackermanna@email.chop.edu or rosenfelde@email.chop.edu.


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