Clinical Research Study Finder

Children's Hospital of Philadelphia leads or participates in hundreds of clinical research studies and clinical trials. Many of the studies that are currently enrolling patients can be found in this database. Use this finder to learn more about the purpose of these studies and clinical trials, find out who can participate, and tell us you're interested in enrolling.

Find a Clinical Research Study

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Dova Study for Children with Immune Thrombocytopenia (ITP)

The Dova study is for children below 18 years with primary Immune Thrombocytopenia (ITP) who have had an insufficient response to previous treatment. The goal of the study is to see if the study drug, Avatrombopag can safely increase platelet counts and improve symptoms for people with ITP. Avatrombopag is an investigational medication designed to make your body produce more platelets. You may be able to join the study if you are:

  • 1 year or older but below 18 years of age
  • Diagnosed with primary ITP for at least 6 months.

Other study requirements will apply.

VR Intervention to Improve Police Safety

The purpose of this research study is to test whether virtual reality (VR) could be a useful way for people with autism to practice interacting with police officers. We are partnering with teens and adults (age 12-60) with a confirmed diagnosis of autism spectrum disorder (ASD). Participants will be asked to make one-to-four virtual study visits, participate in either VR intervention or a treatment-as usual condition, and complete questionnaires and talk about experiences. You will receive compensation for participating.

Imaging Assessment of Bone Sarcomas

This study is looking to recruit CHOP patients 5-30 years old with suspected/ confirmed bone sarcomas. The study is looking to evaluate a new MRI technique to evaluate bones and any mass in them. The study involved an additional imaging sequence performed at the same day as your clinically indicated MRI studies that allows researchers to better visualize the bones. This sequence takes about 30-60 minutes and may be done each time you have a clinically-indicated MRI (up to 3 times). If you're interested in learning more, please contact the study team. 

ARGX-113 study for Adults with Primary Immune Thrombocytopenia

The ARGX-113 study is designed to assess how safe and effective the investigational study drug (efgartigimod) is compared to a placebo (which has no active ingredients) as a possible treatment for adults living with primary immune thrombocytopenia (ITP). The study is blinded, meaning that neither you nor the study team will know which treatment you are receiving but if an emergency occurs, your study doctor will be notified. You will be on the study for about 8 months. The study drug will be infused through the vein (IV) for approximately one hour. Depending on the type of visit, you will be spending about 1 to 3 hours on site. 

You may be able to join the study if you are: 

  1. 18 years or older
  2. Have a confirmed diagnosis of ITP for more than 3 months
  3. Have received at least 1 prior therapy for ITP in the past
  4. Have platelet counts of less than 30,000

Other study requirements will apply.

Vocal Biomarkers of Autism Spectrum Disorder

The goal of this study is to identify unique characteristics in the way kids and teens with Autism Spectrum Disorder (ASD) speak in comparison to typically developing peers. We are looking to partner with children and adolescents ages 6-17 with a confirmed diagnosis of autism spectrum disorder and typically developing children and adolescents. In response to the COVID-19 pandemic, all study activities

may be completed from home. Participants will be asked to complete questionnaires, as well as weekly language-based activities 7 times. You will receive compensation for your participation. Upon request, you will receive a clinical report detailing assessment results. For more information please contact Kimberly Tena at 267-496-6878 or tenak@email.chop.edu.

Comorbidity of Autism and Epilepsy

Dr. William Gaetz. has partnered with pediatric neurologist, Dr. Eric Marsh and neuropsychologist, Dr. Lisa Blaskey to better understand Epilepsy in children who have an Autism Spectrum Disorder (ASD). This study will use a non-invasive brain scanning technology as well as cognitive testing results to understand brain differences in children with Autism and Epilepsy. We hope that the information we get from this study will help children in the future who have ASD. For this research to be successful we need to work with male children with a diagnosis of ASD or ASD and Epilepsy who are 8 to 17 years of age. Families will be reimbursed for their time and have an opportunity to discus their child's cognitive testing results with our neuropsychologist post testing. Please contact our study staff at MEGstudies@email.chop.edu for more information.

What Do You Eat? An Online Study for Youth with ASD

The goal of this research study is to develop an online questionnaire about what youth with Autism Spectrum Disorder (ASD) eat and how it impacts their daily lives. Youth (7-16 years) and their parent will complete a questionnaire about food and eating habits online. Parents will complete an additional child background and medical history questionnaire online. Participants will be paid for their time with an Amazon online gift card.

Autism ETA Cohort Study

Parents and their child between 16 and 21 on the autism spectrum are both asked to partner with us for this study as we learn more about the decisions you make about transportation, including driving. We also hope to learn about how transportation influences quality of life and other outcomes. First, parents will answer questions about themselves and their child. Then, both parents and their child will complete up to six surveys over the course of two years. The surveys will ask about your thoughts and experiences with transportation and driving, quality of life, relationships, and other outcomes.

MRI Study for Prediction of ASD

Thisstudy seeks to understand the key differences and similarities in braindevelopment between infants whose siblings do and do not have autism. Participantswill be asked to make 3 visits to CHOP over time to complete cognitive andbehavioral testing and a non-invasive MRI. Participants will be compensated fortheir time and receive a written feedback report.


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