Clinical Research Finder

Children's Hospital of Philadelphia leads or participates in hundreds of clinical trials. Use this database to learn the purpose of these trials, find out who can participate and more.

Find a Clinical Research Study

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BoneGN

Glomerular disease is a major cause of chronic kidney disease associated with substantial morbidity; children and adults with glomerular disease face many threats to bone health. The purpose of this research study is to understand more about bone strength in children, adolescents and adults with Glomerular disease. This and future research will help us develop treatment guidelines for this population in order to promote bone health and prevent fractures and osteoporosis later in life. We will be evaluating bone quality in 150 participants with Glomerular disease and 120 healthy participants. The study requires 2 visits for a total of 3 hours and that the participants be 5 to 55 years old. The study procedures include blood draws, bone density measures and questionnaires. Compensation will be provided. If interested in participating contact the research coordinator at 267-648-3256.

Vitamin E Supplementation in Hyperinsulinism/Hyperammonemia (HI/HA) Syndrome

Our team is working on a study to see if children with HI/HA Syndrome tolerate Vitamin E supplementation. This is an experimental, non-FDA approved use of Vitamin E which will lead to further studies to evaluate if Vitamin E can be used as a treatment for HI/HA. The study involves taking Vitamin E once a day for two weeks at home, completing a tolerability questionnaires, and two, one-day visits to the CHOP outpatient Center for Human Phenomic Science (one visit before and one visit after taking the Vitamin E supplement for two weeks). During each study visit, fasting oral protein tolerance will be performed and blood samples will be drawn. If you're interested in learning more, please contact us at ackermanna@email.chop.edu or rosenfelde@email.chop.edu.

What Do You Eat? An Online Study for Youth with ASD

The goal of this research study is to develop an online questionnaire about what youth with Autism Spectrum Disorder (ASD) eat and how it impacts their daily lives. Youth (7-16 years) and their parent will complete a questionnaire about food and eating habits online. Parents will complete an additional child background and medical history questionnaire online. Participants will be paid for their time with an Amazon online gift card.

The CARRA Registry

This is an observational registry of children and young adults with pediatric-onset rheumatic conditions such as juvenile idiopathic arthritis (JIA) and Systemic Lupus Erythematosus (SLE) and SLE-like conditions. The registry will be used to answer questions about how safe medications are, how well medications work, and how well patients do over time. Patients who agree to participate will allow their health information to be used for research, complete a brief questionnaire during their clinic visits, and in some cases, be asked to give a sample of blood, urine, cheek swabs, stool, leftover (from clinical procedure) joint fluid, and leftover (from clinical procedure) tissue biopsy.


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