Clinical Research Study Finder

Children's Hospital of Philadelphia leads or participates in hundreds of clinical research studies and clinical trials. Many of the studies that are currently enrolling patients can be found in this database. Use this finder to learn more about the purpose of these studies and clinical trials, find out who can participate, and tell us you're interested in enrolling. You can also look for studies that offer remote participation from home!

Find a Clinical Research Study

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Food Allergy Anxiety

The goal of this study is to identify and measure anxiety symptoms in children and adolescents with food allergy. We are looking for families of children with IgE-mediated food allergies between 8 and 18 years of age to participate. The study procedures involve both the caregiver and child filling out online questionnaires on two separate occasions. If you are interested in participating, you can sign up immediately by clicking the link below: https://is.gd/FoodAllergyAnxiety If you have any questions, please contact the research coordinator, Leah Wilkey, by phone at 215-590-6198 or email at wilkeyl@email.chop.edu.

Social Coordination

The purpose of this study is to understand how motor function- the way we move our faces and bodies- impacts social communication. We are seeking adolescents ages 12-17 with or without ASD or a mixed psychological diagnosis (ADD, ADHD, ODD, or anxiety).  To accommodate COVID protective measures, most of the study tasks can be completed from home through video-based assessment and online questionnaires. Then, families will be asked to make one or two short visits to the Roberts Center. During this visit you will play games and talk with our research staff. All participants will also receive a full psychological work-up, including behavioral testing for ADHD, anxiety, autism, and mood disorders. Participants and their parents are paid for their time completing the virtual visit as well as for time spent completing questionnaires. Each participant also receives a full psychological report and  personalized feedback with recommendations.

SPARK: Simons Foundation Powering Autism Research for Knowledge

The mission of SPARK is to ignite research at an unprecedented scale to improve lives by advancing our understanding of autism. To join this national autism research cohort, individuals with a professional diagnosis of autism and their biological family members will be asked to share information about their medical and family history, as well as provide a DNA sample. Please contact the Center for Autism Research for more information at 1-866-570-6524 or autism@email.chop.edu.

National Pediatric Cardiology Quality Improvement Collaborative

The purpose of this research study is to learn more about improving the treatment and outcomes for patients who have a diagnosis of a single ventricle, such as Hypoplastic Left Heart Syndrome (HLHS) or similar heart defects. You will be asked to fill out a questionnaire called the Ages and Stages Questionnaire about your child. It is used widely in pediatrics to check on babies’ development. We will ask you to fill this out about every three months during your child’s 15 months of life. Also, information will be collected about your child’s surgeries, clinic visits and hospital stays from diagnosis through the first year of life. The information may be used to help us understand an infant's response to surgery and medical treatment and may be used to improve care for children with single ventricles.

Social Processes in Adolescents with Restrictive Eating Disorders

The purpose of this study is to evaluate social interactions in adolescents and whether changes in information can influence social behaviors. This study will focus on behavioral assessments of social processing over time in adolescents. The information collected in this study is essential for developing clinical treatments focused on addressing social processes in adolescents with restrictive eating disorders and to improve our understanding of social processing in adolescents with restrictive eating disorders, informing both future research and clinical care.

PriCARE for Young Parents Yr1

Researchers from General Pediatrics are conducting focus groups on Child Adult Relationship Enhancement in Pediatric Primary Care (PriCARE), a parenting group program that helps to improve children’s behaviors and strengthen the caregiver-child relationship. The researchers are conducting this study to adapt PriCARE for parents and their parenting supports.
Eligibility
Parents who were younger than 21 at the time of the birth of their child, who currently have at least one child between the ages of 2-6, or are a parenting support person of a parent with a child 2-6 years old, are eligible.

Pathways to ASD Diagnosis

The purpose of the study is to learn more about the experience of caregivers who have a child diagnosed with autism. We also want to better understand what is working well in healthcare in the US. This study is open to primary caregivers of a child (aged 3-17) who has been diagnosed with autism spectrum disorder in the last year. Participants must have immigrated to the US and identify as Hispanic or Latinx. Study staff will interview participants about their experiences as a caregiver of an autistic child. This one-time interview will last 60-90 minutes in Spanish or English.

Approach Avoidance Model of Repetitive Behaviors

The goal of this research study is to learn about experiences with repetitive behaviors from autistic teens and their families. In order to learn about your experiences with repetitive behaviors, you will be invited to complete a set of online questionnaires about your (or your teen's) experiences. The goal of this study is to promote advocacy and transparency for autistic teens' lived experiences. A small subset of teens may also be asked to complete a brain MRI and additional behavioral assessments, if they are interested. Participating in the MRI and further behavioral assessments is voluntary and is not required to complete the online surveys.

Preventing Distracted Driving

The Center for Injury Research & Prevention is seeking teens age 16-19 and a parent to participate in a research study about distracted driving. Both teens and parents must be licensed drivers and use smartphones. The purpose of this research study is to figure out if a new smartphone app impacts distracted driving, and to learn parent and teen perspectives on the app. Participants will be asked to complete occasional surveys and use a smartphone app for up to 3 weeks. The entire study can be completed remotely, and no visits to CHOP are required. Families are compensated for their time in the study. 

ADHD ETA Driving Cohort Study

We are asking both parents and their child between ages 16-18 who recently received their learner’s permit to partner with us as we learn more about teen driving safety. We are looking for children both with and without an ADHD diagnosis to participate. First, parents will answer questions about themselves and their child. Then, both parents and their child will complete up to five surveys over the course of two to three years. The surveys will ask about your thoughts and experiences with driving, health, and other outcomes.


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