Education and Training
Medical School
University of Washington, Seattle WA
Internship
Radiology, University of Virginia, Charlottesville, Virginia
Residency
Department of Radiology, University of Virginia, Charlottesville, Virginia
Fellowship
Department of Radiology, University of Virginia, Charlottesville, Virginia
Department of Radiology (Pediatric) Cincinnati Children's Hospital, Cincinnati, Ohio
Board Certification
Diagnostic Radiology – American Board of Radiology
Undergraduate Degree
University of Virginia, Charlottesville, Virginia (Biomedical Engineering)
Graduate Degree
Massachusetts Institute of Technology, Cambridge, Massachusetts (Electrical Engineering)
Titles and Academic Titles
Pediatric radiologist
Publications
Abstracts
2004
de Lange E.E., Altes T.A., Patrie J., Gaare J., Brookeman J.R., Mugler J.P. III. Hyperpolarized Helium-3 MR Imaging of the lung in asthmatics: Evaluation of changes following methacholine and exercise challenge. Radiological Society of North America,Chicago, IL, 2004.
Gaare J., Altes T.A., Knake J.J., Brookeman J.R., Mugler J.P. III, de Lange E.E. Hyperpolarized Helium-3 MR (H3-HeMR) Imaging of the lung in asthmatics: Ventilation changes following treatment with albuterol. Radiological Society of North America, Chicago, IL, 2004.
Altes T.A ., Zhang H., Salerno M., Brookeman J.R., de Lange E.E., Mugler J.P. III. Repeatability of the Hyperpolarized Helium-3 Apparent Diffusion Coefficient. Radiological Society of North America, Chicago, IL, 2004.
Altes T.A ., Mugler J.P. III, Mata J., Benjamin-Watkins J., Herily S., de Lange E.E., Brookeman J.R. Assessment of lung development using hyperpolarized helium-3 MR lung imaging. International Society of Magnetic Resonance Medicine [ISMRM] , Kyoto, Japan, 2004.
2003
Salerno M., Mugler J.P. III, Brookeman J.R., de Lange E.E., Altes T.A. Detection of early smoking related lung disease with diffusion-weighted hyperpolarized helium-3 MR lung imaging. Radiological Society of North America, Chicago, IL, 2003.
Rehm P.K., Altes T.A ., Ciambotti J.M., Daniel T., Gay S.B., Olazagasti J. CT-guided radionuclide localization of small pulmonary nodules of intraoperative gamma probe localization. Radiological Society of North America, Chicago, IL, 2003.
Miller G.W., Altes T.A., Mugler J.P. III. Multi-contrast radial spin-echo MR imaging for the simultaneous acquisition of T1, proton density and T2-weighted images. Radiological Society of North America, Chicago, IL, 2003.
de Lange E.E., Altes T.A., Harding D., Harrell F., Mata J., Wright C. Hyperpolarized Gas MR imaging of the lung: Safety assessment of inhaled helium-3. Radiological Society of North America, Chicago, IL, 2003.
Mata J., Altes T.A., Knake J.J., Mugler J.P. III, Brookeman J.R., de Lange E.E. Hyperpolarized 3-Helium MR imaging of the lung: Effect of subject immobilization on the occurrence of ventilation defects. Radiological Society of North America, Chicago, IL, 2003.
de Lange E.E., Altes T.A ., Alford B.A., Mugler J.P. III. Hyperpolarized helium-3 MR imaging of the lung in asthmatics: Correlation of imaging findings with clinical symptoms and spirometry. European Society of Thoracic Imaging , Lausanne, Switzerland, June 14-18, 2003.
2002
Altes T.A., Ciambotti J.M., McIlhenny J., Conaway M.R., Saltzman L., de Lange E.E. Inter and intra reader variability study: Scoring hyperpolarized helium-3 MR lung ventilation imaging. Radiological Society of North America, Chicago, IL, 2002.
Altes T.A ., Samee S.S., Ciambotti J.M., Mata J.F., Platts-Mills T.M., de Lange E.E. Hyperpolarized helium-3 MR imaging of asthma induction and reversal. Radiological Society of North America, Chicago, IL, 2002.
2001
Altes T.A., Rehm P., Brookeman J.R., Truwit J.D., de Lange E.E. Ventilation imaging of the lung: Comparison of hyperpolarized Helium-3 MR and Xenon-133 scintigraphy. Radiological Society of North America, Chicago, IL, 2001.
Altes T.A ., Cunningham A., Conaway M., de Lange E.E. Hyperpolarized helium-3 MR imaging of the lung airspaces: Scoring ventilation defects. Radiological Society of North America, Chicago, IL, 2001.
Salerno M., de Lange E.E., Altes T.A., Brookeman J.R., Jones D.R., Mugler J.P. III. High temporal resolution interleaved-spiral dynamic hyperpolarized helium-3 MR imaging of patients with lung transplants: Assessment of pulmonary gas flow as a potential method for early diagnosis of rejection. Radiological Society of North America, Chicago, IL, 2001.
Ray N., Acton S.T., Altes T.A., de Lange E.E. Ventilation analysis by merging parametric active contours within MRI imagery. Proceedings, IEEE International Conference on Image Processing, Thessalonika, Greece, October 7-10, 2001.
Altes T.A., Samee S.S., Salerno M., Alford B.A., Mata J., Menon A., Brookeman J.R., Platts-Mills T.A.E., de Lange E.E. Hyperpolarized helium-3 MR imaging of methacholine challenge testing in asthmatics. International Society of Magnetic Resonance in Medicine. [ISMRM], Glasgow, Scotland, 2001.
2000
Altes T.A., Power P.L., Knight-Scott J., Rakes G., Platts-Mills T.A.E., de Lange E.E., Alford B.A., Mugler J.P. III, Brookeman J.R. Hyperpolarized 3He lung ventilation imaging in asthmatics: Preliminary results. ISMRM, Denver, CO, 2000.
Books
Altes T.A., Brody A. The role of imaging in asthma, In childhood asthma: Breaking down barriers, Szefler SJ, Editor, 2004 (in press).
deLange E.E., Altes T.A. Asthma: Assessing the lung ventilation with hyperpolarized helium-3 MR imaging. In: Functional lung imaging, Lipson DA, Van Beek EJR, Ed. Marcel Dekker, Inc., New York, NY, 2003 (in press).
Posters and Presentations
Posters
2004
Ruppert K., Mata J., Brookeman J.R., Hagspiel K.D., Benjamin-Watkins J., Altes T.A ., Tobias W., Wang J., Cates G., Mugler J.P. III. 129Xe lung imaging with a single-shot circular RARE sequence. ISMRM, 2004.
Miller W., Mugler J.P. III, Altes T.A., de Lange E.E., Brookeman J.R. An improved method for generating oxygen maps with He-3 MRI. ISMRM, 2004.
Miller W., Altes T.A ., Brookeman J.R., de Lange E.E., Mata J., Mugler J.P. III. Improving the quality of 3D hyperpolarized gas images using feedback-controlled flip-angle evolution. ISMRM, 2004.
2003
Altes T.A., Mugler J.P. III, Brookeman J.R., de Lange E.E., Salerno M. Detection of early smoking related lung disease with diffusion weighted hyperpolarized helium-3 MR lung imaging. National COPD Conference, November 14-15, 2003.
Rehm P.K., Altes T.A., Williams M.B., Stolin V.A., Cundu B., Daniels T.M. Intraparenchymal retention of Tc-99M macroaggregated albumin (MAA), unfiltered Tc-99m sulfur colloid (Sc) and Tc-99m pertechnetate (TCO4) in lung after transthoracic injection. Society of Nuclear Medicine, 2003.
Altes T.A., Samee S.S., Ciambotti J.M., Mata J.F., Platts-Mills T.M., de Lange E.E. Hyperpolarized Helium-3 MR imaging of asthma induction. ISMRM, 2003.
2002
Cooley B., Acton S., Salerno S., Ray N., de Lange E.E., Brookeman J.R., Tustison N., Altes T.A. Automated scoring of hyperpolarized helium-3 MR lung ventilation images: Initial development and validation. ISMRM, 2002.
Altes T.A ., Froh D.K., Salerno M., Cook C.D., Mata J., Mugler J.P. III, de Lange E.E.,Brookeman J.R. Hyperpolarized Helium-3 MR imaging of lung ventilation changes following airway mucus clearance treatment in cystic fibrosis. ISMRM, 2002.
2001
Froh D.K., Altes T.A., Cook C.D., Mata J., Mugler J.P. III, de Lange E.E., Brookeman J.R. Imaging of lung ventilation in Cystic Fibrosis with Hyperpolarized Helium-3 Magnetic Resonance (MR), American Thoracic Society , San Francisco, California, 2001.
2000
Altes T.A., Powers P.L., Knight-Scott J., Rakes G., Platts-Mills T.A.E., de Lange E.E., Alford B.A., Mugler J.P. III, Brookeman J.R. Hyperpolarized 3He MR lung ventilation imaging in asthmatics. ESMRB, Paris, France, 2000.
Editorial and Academic Positions
2005-present
Staff Radiologist, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
2003-present
Staff Radiologist, University of Virginia Hospital, Charlottesville, Virginia
Staff Radiologist, Cincinnati Children's Hospital, Cincinnati Ohio
Staff Radiologist, University of Cincinnati Hospital, Cincinnati, Ohio
Staff Radiologist, Shriners Hospital for Children, Cincinnati, Ohio