Education and Training

Medical School

University of Washington, Seattle WA

Internship

Radiology, University of Virginia, Charlottesville, Virginia

Residency

Department of Radiology, University of Virginia, Charlottesville, Virginia

Fellowship

Department of Radiology, University of Virginia, Charlottesville, Virginia
Department of Radiology (Pediatric) Cincinnati Children's Hospital, Cincinnati, Ohio

Board Certification

Diagnostic Radiology – American Board of Radiology

Undergraduate Degree

University of Virginia, Charlottesville, Virginia (Biomedical Engineering)

Graduate Degree

Massachusetts Institute of Technology, Cambridge, Massachusetts (Electrical Engineering)

Titles and Academic Titles

Pediatric radiologist

Publications

Abstracts

2004

de Lange E.E., Altes T.A., Patrie J., Gaare J., Brookeman J.R., Mugler J.P. III. Hyperpolarized Helium-3 MR Imaging of the lung in asthmatics: Evaluation of changes following methacholine and exercise challenge. Radiological Society of North America,Chicago, IL, 2004.

Gaare J., Altes T.A., Knake J.J., Brookeman J.R., Mugler J.P. III, de Lange E.E. Hyperpolarized Helium-3 MR (H3-HeMR) Imaging of the lung in asthmatics: Ventilation changes following treatment with albuterol. Radiological Society of North America, Chicago, IL, 2004.

Altes T.A ., Zhang H., Salerno M., Brookeman J.R., de Lange E.E., Mugler J.P. III. Repeatability of the Hyperpolarized Helium-3 Apparent Diffusion Coefficient. Radiological Society of North America, Chicago, IL, 2004.

Altes T.A ., Mugler J.P. III, Mata J., Benjamin-Watkins J., Herily S., de Lange E.E., Brookeman J.R. Assessment of lung development using hyperpolarized helium-3 MR lung imaging. International Society of Magnetic Resonance Medicine [ISMRM] , Kyoto, Japan, 2004.

2003

Salerno M., Mugler J.P. III, Brookeman J.R., de Lange E.E., Altes T.A. Detection of early smoking related lung disease with diffusion-weighted hyperpolarized helium-3 MR lung imaging. Radiological Society of North America, Chicago, IL, 2003.

Rehm P.K., Altes T.A ., Ciambotti J.M., Daniel T., Gay S.B., Olazagasti J. CT-guided radionuclide localization of small pulmonary nodules of intraoperative gamma probe localization. Radiological Society of North America, Chicago, IL, 2003.

Miller G.W., Altes T.A., Mugler J.P. III. Multi-contrast radial spin-echo MR imaging for the simultaneous acquisition of T1, proton density and T2-weighted images. Radiological Society of North America, Chicago, IL, 2003.

de Lange E.E., Altes T.A., Harding D., Harrell F., Mata J., Wright C. Hyperpolarized Gas MR imaging of the lung: Safety assessment of inhaled helium-3. Radiological Society of North America, Chicago, IL, 2003.

Mata J., Altes T.A., Knake J.J., Mugler J.P. III, Brookeman J.R., de Lange E.E. Hyperpolarized 3-Helium MR imaging of the lung: Effect of subject immobilization on the occurrence of ventilation defects. Radiological Society of North America, Chicago, IL, 2003.

de Lange E.E., Altes T.A ., Alford B.A., Mugler J.P. III. Hyperpolarized helium-3 MR imaging of the lung in asthmatics: Correlation of imaging findings with clinical symptoms and spirometry. European Society of Thoracic Imaging , Lausanne, Switzerland, June 14-18, 2003.

2002

Altes T.A., Ciambotti J.M., McIlhenny J., Conaway M.R., Saltzman L., de Lange E.E. Inter and intra reader variability study: Scoring hyperpolarized helium-3 MR lung ventilation imaging. Radiological Society of North America, Chicago, IL, 2002.

Altes T.A ., Samee S.S., Ciambotti J.M., Mata J.F., Platts-Mills T.M., de Lange E.E. Hyperpolarized helium-3 MR imaging of asthma induction and reversal. Radiological Society of North America, Chicago, IL, 2002.

2001

Altes T.A., Rehm P., Brookeman J.R., Truwit J.D., de Lange E.E. Ventilation imaging of the lung: Comparison of hyperpolarized Helium-3 MR and Xenon-133 scintigraphy. Radiological Society of North America, Chicago, IL, 2001.

Altes T.A ., Cunningham A., Conaway M., de Lange E.E. Hyperpolarized helium-3 MR imaging of the lung airspaces: Scoring ventilation defects. Radiological Society of North America, Chicago, IL, 2001.

Salerno M., de Lange E.E., Altes T.A., Brookeman J.R., Jones D.R., Mugler J.P. III. High temporal resolution interleaved-spiral dynamic hyperpolarized helium-3 MR imaging of patients with lung transplants: Assessment of pulmonary gas flow as a potential method for early diagnosis of rejection. Radiological Society of North America, Chicago, IL, 2001.

Ray N., Acton S.T., Altes T.A., de Lange E.E. Ventilation analysis by merging parametric active contours within MRI imagery. Proceedings, IEEE International Conference on Image Processing, Thessalonika, Greece, October 7-10, 2001.

Altes T.A., Samee S.S., Salerno M., Alford B.A., Mata J., Menon A., Brookeman J.R., Platts-Mills T.A.E., de Lange E.E. Hyperpolarized helium-3 MR imaging of methacholine challenge testing in asthmatics. International Society of Magnetic Resonance in Medicine. [ISMRM], Glasgow, Scotland, 2001.

2000

Altes T.A., Power P.L., Knight-Scott J., Rakes G., Platts-Mills T.A.E., de Lange E.E., Alford B.A., Mugler J.P. III, Brookeman J.R. Hyperpolarized 3He lung ventilation imaging in asthmatics: Preliminary results. ISMRM, Denver, CO, 2000.

 

 

Books

Altes T.A., Brody A. The role of imaging in asthma, In childhood asthma: Breaking down barriers, Szefler SJ, Editor, 2004 (in press).

deLange E.E., Altes T.A. Asthma: Assessing the lung ventilation with hyperpolarized helium-3 MR imaging. In: Functional lung imaging, Lipson DA, Van Beek EJR, Ed. Marcel Dekker, Inc., New York, NY, 2003 (in press).

Posters and Presentations

Posters

2004

Ruppert K., Mata J., Brookeman J.R., Hagspiel K.D., Benjamin-Watkins J., Altes T.A ., Tobias W., Wang J., Cates G., Mugler J.P. III. 129Xe lung imaging with a single-shot circular RARE sequence. ISMRM, 2004.

Miller W., Mugler J.P. III, Altes T.A., de Lange E.E., Brookeman J.R. An improved method for generating oxygen maps with He-3 MRI. ISMRM, 2004.

Miller W., Altes T.A ., Brookeman J.R., de Lange E.E., Mata J., Mugler J.P. III. Improving the quality of 3D hyperpolarized gas images using feedback-controlled flip-angle evolution. ISMRM, 2004.

2003

Altes T.A., Mugler J.P. III, Brookeman J.R., de Lange E.E., Salerno M. Detection of early smoking related lung disease with diffusion weighted hyperpolarized helium-3 MR lung imaging. National COPD Conference, November 14-15, 2003.

Rehm P.K., Altes T.A., Williams M.B., Stolin V.A., Cundu B., Daniels T.M. Intraparenchymal retention of Tc-99M macroaggregated albumin (MAA), unfiltered Tc-99m sulfur colloid (Sc) and Tc-99m pertechnetate (TCO4) in lung after transthoracic injection. Society of Nuclear Medicine, 2003.

Altes T.A., Samee S.S., Ciambotti J.M., Mata J.F., Platts-Mills T.M., de Lange E.E. Hyperpolarized Helium-3 MR imaging of asthma induction. ISMRM, 2003.

2002

Cooley B., Acton S., Salerno S., Ray N., de Lange E.E., Brookeman J.R., Tustison N., Altes T.A. Automated scoring of hyperpolarized helium-3 MR lung ventilation images: Initial development and validation. ISMRM, 2002.

Altes T.A ., Froh D.K., Salerno M., Cook C.D., Mata J., Mugler J.P. III, de Lange E.E.,Brookeman J.R. Hyperpolarized Helium-3 MR imaging of lung ventilation changes following airway mucus clearance treatment in cystic fibrosis. ISMRM, 2002.

2001

Froh D.K., Altes T.A., Cook C.D., Mata J., Mugler J.P. III, de Lange E.E., Brookeman J.R. Imaging of lung ventilation in Cystic Fibrosis with Hyperpolarized Helium-3 Magnetic Resonance (MR), American Thoracic Society , San Francisco, California, 2001.

2000

Altes T.A., Powers P.L., Knight-Scott J., Rakes G., Platts-Mills T.A.E., de Lange E.E., Alford B.A., Mugler J.P. III, Brookeman J.R. Hyperpolarized 3He MR lung ventilation imaging in asthmatics. ESMRB, Paris, France, 2000.

 

 

 

 

Editorial and Academic Positions

2005-present

Staff Radiologist, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

2003-present

Staff Radiologist, University of Virginia Hospital, Charlottesville, Virginia

Staff Radiologist, Cincinnati Children's Hospital, Cincinnati Ohio

Staff Radiologist, University of Cincinnati Hospital, Cincinnati, Ohio

Staff Radiologist, Shriners Hospital for Children, Cincinnati, Ohio