Background

Dr. Andrea Freeman Duncan received her medical degree from the University of Texas Southwestern Medical Center at Dallas in 2002. She completed her pediatric residency and fellowship in Neonatal-Perinatal Medicine at the University of Texas Southwestern Medical Center at Dallas. She was subsequently a clinical scientist faculty member and mentor at the University of New Mexico and the University of Texas at Houston McGovern Medical School.

Dr. Duncan joined the faculty of the University of Pennsylvania and Children's Hospital of Philadelphia in 2019 and is the Medical Director of the Neonatal Follow-up Program there. She is the Principal Investigator for Neurodevelopmental Follow-up for the Children's Hospital of Philadelphia site of the Eunice Kennedy Shriver National Institute of Child Health and Development Neonatal Research Network. She is also the Principal Investigator for the Children's Hospital of Philadelphia site of the Cerebral Palsy Foundation Early Detection of Cerebral Palsy (CP) Network.

Dr. Duncan's main research interest is in long-term medical and neurodevelopmental outcomes of NICU graduates. This has included previous research in the effects of very-low-birth weight and postnatal growth on blood pressure during the first three years of life, the role of ethnic and social factors on Bayley Scales of Infant Development Cognitive and Language Scale scores in children born extremely premature, the effect of parenting style on self-regulation in children born preterm, the correlation of neuroimaging with outcomes in children born extremely preterm, motor outcomes in high-risk children, and the effects of implementation of the international guidelines for early assessment for CP on diagnoses and outcomes in high risk infants. Her current research involves evaluation of executive functioning and brain connectivity in high-risk infants and infants with CP, parenting style in high risk infant development, and the use of implementation science to translate evidence to practice.

Education and Training

Medical School

MD - University of Texas Southwestern at Dallas, Dallas, TX

Residency

Pediatrics - University of Texas Southwestern at Dallas, Dallas, TX

Fellowship

Neonatal-Perinatal Medicine - University of Texas Southwestern at Dallas, Dallas, TX

Board Certification

Neonatal-Perinatal Medicine
Pediatrics

Graduate Degree

MS in Clinical Research - University of New Mexico, Albuquerque, NM

Titles and Academic Titles

Medical Director, Neonatal Follow-up Program

Attending Neonatologist

Associate Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Research Interests

Long-term medical and neurodevelopmental outcomes of NICU graduates
Evaluation of executive functioning and brain connectivity in high-risk infants and infants with CP
Parenting style in high risk infant development
Use of implementation science to translate evidence to practice

Publications

Papers

2019

DeMaster D, Bick J, Johnson J, Montroy J, Landry S, Duncan, A: Nurturing the preterm infant brain: Leveraging neuroplasticity to improve neurobehavioral outcomes. Pediatr Res. 2019 Jan;85(2):166-175. doi: 10.1038/s41390-018-0203-9. Epub 2018 Oct 16.

Duncan AF, Bann CM, Dempsey AG, Peralta-Carcelen M, Hintz S: Behavioral Deficits at 18-22 Months of Age are Associated with Early Cerebellar Injury and Cognitive and Language Performance in Extremely Preterm Children. J Pediatr. 2019 Jan;204:148-156.e4. doi: 10.1016/j.jpeds.2018.08.059. Epub 2018 Oct 3.

2018

Dempsey AG,  Barton AK,  Duncan AF: Differences in performance on developmental tasks in young children across digital and paper-based modalities: a feasibility trial. J Dev Behav Pediatr. 2018 Dec;39(9):726-735. doi: 10.1097/DBP.0000000000000618.

Hintz SR, Vohr BR, Bann CM, Taylor HG, Das A, Ball MB, Gustafson KE, Yolton K, Watson V, Lowe J, DeAnda ME, Hack M*, Finer N, Van Meurs KP, Shankaran S, Pappas A, Barnes PD, Bulas D, Slovis TL, Wilson-Costello DE, Heyne RJ, Harmon H, Peralta-Carcelen M, Adams-Chapman I, Duncan AF, et al and for the Eunice Kennedy Shriver NICHD Neonatal Research Network: Preterm Neuroimaging and School-Age Cognitive Outcomes. Pediatrics 142(1), July 2018 Notes: DOI: 10.1542/peds.2017-4058.

Vohr BR, Heyne R, Bann CM, Das A, Higgins RD, Hintz SR; Eunice Kennedy Shriver National Institute of Child Health, and Development Neonatal Research Network: Extreme Preterm Infant Rates of Overweight and Obesity at School Age in the SUPPORT Neuroimaging and Neurodevelopmental Outcomes Cohort. J Pediatr May 2018 Notes: pii: S0022-3476(18)30627-9. doi: 10.1016/j.jpeds.2018.04.073.

Adams-Chapman I, Heyne R, DeMauro S, Duncan AF, Hintz S, Pappas A, Vohr B, McDonald S, Das A, Newman J, Higgins R: Neurodevelopmental Impairment Among Extremely Preterm Infants in the Neonatal Research Network. Pediatrics 141(5): 2017-3091, May 2018.

Sarkar S, Shankaran S, Barks J, Do BT, Laptook AR, Das A et al for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network: Outcome of Preterm Infants with Transient Cystic Periventricular Leukomalacia on Serial Cranial Imaging Up to Term Equivalent Age  J Pediatr  195: 59-65, April 2018.

Findley T, Patel M, Chapman J, Brown D, Duncan AF: Acquired versus congenital neonatal purpura fulminans: a case report and literature review. J Pediatr Hematol Oncol April 2018 Notes: DOI: 10.1097/MPH.0000000000001150.

2017

Younge N, Goldstein RF, Bann CM, Hintz SR, Patel RM, Smith PB, Bell EF, Rysavy MA, Duncan AF, Vohr BR, Das A, Goldberg RN, Higgins RD, Cotton CM, for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network: Survival and Neurodevelopmental Outcomes of Periviable Infants  NEJM  376(7): 617-628, 2017.

Watterberg KL, Fernandez E, Walsh MC, Truog WE, Stoll BJ, Sokol GM, Kennedy KA, Fraga MV, Beauman SS, Carper B, Das A, Duncan AF, Buss WF, Gauldin C, Lacy CB, Sanchez PJ, Chawla S, Lakshminrusimha S, Cotten CM, Van Meurs KP, Poindexter BB, Bell EF, Carlo WA, Devaskar U, Wyckoff MH, Higgins RD: Barriers to enrollment in a randomized controlled trial of hydrocortisone for cardiovascular insufficiency in term and late preterm newborn infants    J Perinatol 37(11), November 2017 Notes: doi: 10.1038/jp.2017.131.

James J, Munson D, DeMauro SB, Langer JC, Dworetz AR, Natarajan G, et al and Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network: Outcomes of Preterm Infants following Discussions about Withdrawal or Withholding of Life Support   J Pediatr November 2017 Notes: doi: 10.1016/j.jpeds.2017.05.056. Epub 2017 Jun 21.

Peralta-Carcelen M, Carlo WA, Pappas A, Vaucher YE, Yeates KO, Phillips VA, Gustafson KE, Payne AF, Duncan AF, Newman JE, Bann C, and other follow up PI for the NICHD Neonatal Network: Behavioral problems and socioemotional competence at 18-22 months of extremely premature children. Pediatrics May 2017.

Duncan AF, Frankfurt JA, Heyne RJ, Rosenfeld CR: Biomarkers of Adiposity are Elevated in Preterm Very-Low-Birth-Weight Infants at 1, 2 and 3 Years of Age. Pediatr Res 81(5): 780-786, May 2017 Notes: DOI: 10.1038/pr.2017.11.

2016

Meyers J, Bann CM, Stoll BJ, D'Angio C, Bell E, Duncan AF, Guillet R: Neurodevelopmental Outcomes in Postnatal Growth-Restricted Preterm Infants with Postnatal Head-Sparing  J Perinatol 36(12): 1116-1121, Dec 2016.

2015

Hoffman L, Bann C, Higgins R, Vohr B, et al and for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network: Developmental outcomes of extremely preterm infants born to adolescent mothers. Pediatrics  135(6): 1082-92, 2015.

Duncan A F, Bann C, Boatman C, Hintz S R, Vaucher Y E, Vohr B R, Yolton K, Heyne R J: Do currently recommended Bayley-III cutoffs overestimate motor impairment in infants born <27 weeks gestation? Journal of perinatology : official journal of the California Perinatal Association 35(7): 516-21, Jul 2015.

2014

Lowe Jean, Erickson Sarah J, MacLean Peggy, Duvall Susanne W, Ohls Robin K, Duncan Andrea F: Associations between maternal scaffolding and executive functioning in 3 and 4 year olds born very low birth weight and normal birth weight. Early human development 90(10): 587-93, Oct 2014.

Morriss Frank H, Saha Shampa, Bell Edward F, Colaizy Tarah T, Stoll Barbara J, Hintz Susan R, Shankaran Seetha, Vohr Betty R, Hamrick Shannon E G, Pappas Athina, Jones Patrick M, Carlo Waldemar A, Laptook Abbot R, Van Meurs Krisa P, Sánchez Pablo J, Hale Ellen C, Newman Nancy S, Das Abhik, Higgins Rosemary D: Surgery and neurodevelopmental outcome of very low-birth-weight infants. JAMA pediatrics 168(8): 746-54, Aug 2014.

Duncan A F, Caprihan A, Montague E Q, Lowe J, Schrader R, Phillips J P: Regional cerebral blood flow in children from 3 to 5 months of age. AJNR. American journal of neuroradiology 35(3): 593-8, Mar 2014.

2013

Lowe Jean R, Duncan Andrea Freeman, Bann Carla M, Fuller Janell, Hintz Susan R, Das Abhik, Higgins Rosemary D, Watterberg Kristi L: Early working memory as a racially and ethnically neutral measure of outcome in extremely preterm children at 18-22 months. Early human development 89(12): 1055-61, Dec 2013.

Lowe Jean R, Nolen Tracy L, Vohr Betty, Adams-Chapman Ira, Duncan Andrea F, Watterberg Kristi: Effect of primary language on developmental testing in children born extremely preterm. Acta paediatrica (Oslo, Norway : 1992) 102(9): 896-900, Sep 2013.

2012

Frankfurt Joshua A, Duncan Andrea F, Heyne Roy J, Rosenfeld Charles R: Renal function and systolic blood pressure in very-low-birth-weight infants 1-3 years of age. Pediatric nephrology (Berlin, Germany) 27(12): 2285-91, Dec 2012.

Duncan Andrea Freeman, Watterberg Kristi L, Nolen Tracy L, Vohr Betty R, Adams-Chapman Ira, Das Abhik, Lowe Jean: Effect of ethnicity and race on cognitive and language testing at age 18-22 months in extremely preterm infants. The Journal of pediatrics 160(6): 966-71.e2, Jun 2012.

Lowe Jean R, MacLean Peggy C, Duncan Andrea F, Aragón Crystal, Schrader Ronald M, Caprihan Arvind, Phillips John P: Association of maternal interaction with emotional regulation in 4- and 9-month infants during the Still Face Paradigm. Infant behavior & development 35(2): 295-302, Apr 2012.

Lowe Jean R, Erickson Sarah J, Schrader Ron, Duncan Andrea F: Comparison of the Bayley II Mental Developmental Index and the Bayley III Cognitive Scale: are we measuring the same thing? Acta paediatrica (Oslo, Norway : 1992) 101(2): e55-8, Feb 2012.

2011

Duncan Andrea F, Heyne Roy J, Morgan Janet S, Ahmad Naveed, Rosenfeld Charles R: Elevated systolic blood pressure in preterm very-low-birth-weight infants u88043 years of life. Pediatric nephrology (Berlin, Germany) 26(7): 1115-21, Jul 2011.

2009

Duncan Andrea Freeman, Caughy Margaret O'Brien: Parenting style and the vulnerable child syndrome. Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc 22(4): 228-34, Nov 2009.

2008

Duncan Andrea F, Rosenfeld Charles R, Morgan Janet S, Ahmad Naveed, Heyne Roy J: Interrater reliability and effect of state on blood pressure measurements in infants 1 to 3 years of age. Pediatrics 122(3): e590-4, Sep 2008.

Books

Chapters

2016

Stewart J, Hernandez F, Duncan A: Follow-up Care of Very Preterm and Very Low Birthweight Infants. Cloherty and Stark's Manual of Neonatal Care, 8th ed.  Eric Eichenwald, Ann Hansen, Camilia Martin and Ann Stark (eds.). 2016.

Posters and Presentations

2018

Sabates RS, Bell CS, Dempsey AG, Duncan AF: Predictive Validity of the Ages and Stages Questionnaire in Toddlers Born Less than 28 Weeks Gestation. Poster presentation, Pediatric Academic Societies' Meeting, Toronto, Canada. May 2018.

Peralta-Carcelen M, Hintz SR, Higgins RD, Duncan AF, Vohr BR, Bann C: Factors associated with autism spectrum disorder features at early school age among extremely preterm children. Poster Presentation, Pediatric Academic Society Meeting, Toronto Ontario, Canada May 2018.

McKay S, Domonoske C, McKay K, Duncan AF. : Immunization practices in the NICU and adverse events following vaccination in infants admitted to the NICU  Poster presentation, Pediatric Academic Societies' Meeting, Toronto, Canada May 2018.

Jensen EA, Dysart K, Bamat NA, Kirpalani H, Eichenwald E, DeMauro SB, Gantz M, McDonald S, Keszler M, Laughon M, Poindexter B, Duncan AF, Yoder BA: Development of a Revised Severity Based Definition of Bronchopulmonary Dysplasia: Accounting for Modern Respiratory Care. Poster Presentation, Pediatric Academic Societies' Meeting, Toronto, Canada. May 2018.

Brumbaugh JE, Sridhar A, Hansen NI, Das A, Bell EF, Colaizy T, Rysavy MA, Carlo W, Hintz SR, Vohr BR, Duncan AF, Stoll B, Wyckoff M, Baack ML, DeMauro SB, Higgins RD: The Tiniest Babies: Outcomes of Infants with Birth Weight Less than 400 Grams. Poster Presentation, Pediatric Academic Societies' Meeting, Toronto, Canada May 2018.

Boghossian N, Tan S, Bell EF, Rysavy MA, Carlo W, Hintz SR, Ambalavanan N, Stoll B, Tyson J, Lantos JD,  Duncan AF, Das A, Higgins RD: Sex Differences in Extremely Preterm Infant Outcomes over Time. Poster presentation, Pediatric Academic Societies' Meeting, Toronto, Canada. May 2018.

2017

Sabates R, Bell C, Dempsey A, Duncan AF: Predictive Validity of the Ages and Stages Questionnaire in Toddlers Born Less than 28 Weeks Gestation. Poster Presentation, Society for Developmental and Behavioral Pediatrics (SDBP) annual meeting, Cleveland, OH October 2017.

Duncan A: Neurodevelopmental Outcomes in Premature Infants with Short Bowel Syndrome. Poster Presentation, American Academy of Pediatrics Section on Neonatal-Perinatal Medicine September 2017.

Rysavy MA, Colaizy TT, Bann CM, Hintz SR, DeMauro SB, Duncan AF, Vohr BR, Peralta-Carcelen AM, Bell EF, and the Eunice Kennedy Shriver NICHD Neonatal Research Network: Expanding the Frame- Outcomes Following Extremely Preterm Birth Beyond Neurodevelopmental Impairment. Poster presentation, Pediatric Academic Societies' Meeting, San Francisco, CA May 2017.

Meyers JM, Guillet R, Tan S, Bell EF, Duncan AF, Stoll BJ, D'Angio CT for the NICHD Neonatal Research Network: Neurodevelopmental Outcomes in Extremely Premature Infants with Linear Growth Restriction. Poster presentation,Pediatric Academic Societies' Meeting. San Francisco CA May 2017.

Adams-Chapman I, Heyne R, Duncan AF, Peralta M, Purdy I, McDonald SA for the NICHD Neonatal Research Network: Changing Prevalence and Severity of Cerebral Palsy Among ELBW Infants in NRN Over Ten Years  Poster presentation, Pediatric Academic Societies' Meeting, San Francisco CA, May 2017.

Findley T, Patel M, Chapman J, Brown D, Duncan AF: Case Report: Acquired versus congenital neonatal purpura fulminans. Poster presentation, Southern Society for Pediatric Research Meeting, New Orleans, LA February 2017.

Invited Lectures

2018

Duncan AF. "Early Diagnosis and Intervention for Cerebral Palsy: Translation of the 2017 International Guidelines into Clinical Practice", Pediatric Academic Societies' Meeting, Toronto, Canada. May, 2018.

Duncan AF. "Early Detection of Cerebral Palsy SWOT World Café", Cerebral Palsy Foundation, Implementation of Early Detection and Intervention for Cerebral Palsy Conference, Columbus, OH. Mar, 2018.

Duncan AF. "Neuroimaging in the Detection of Cerebral Palsy", Cerebral Palsy Foundation, Implementation of Early Detection and Intervention for Cerebral Palsy Conference, Columbus, OH. Mar, 2018.

Duncan AF. "Implementation of the Early Intervention and Assessment for Cerebral Palsy Guidelines", Regional Neonatal Evaluation and Outcomes Network Annual Meeting, Temple, Texas. Feb, 2018.

Duncan AF. "Predictive Validity of the Ages and Stages Questionnaire in Toddlers Born Less than 28 Weeks Gestation", Oral presentation, Southern Society for Pediatric Research, New Orleans, LA. Feb, 2018.

2017

Duncan AF. "Cerebral Palsy: Improvising Outcomes Through Early Diagnosis and Intervention", Society for Developmental and Behavioral Pediatrics, Workshop Presentation, Cleveland, OH. Oct, 2017.

Duncan AF. "Digital Screening in Child Development", Society for Developmental and Behavioral Pediatrics, Workshop Presentation, Cleveland, OH. Oct, 2017.

Duncan AF. "Standardization of Developmental Assessments", Regional Neonatal Evaluation and Outcomes Network Annual Meeting, Houston, Texas. Feb, 2017.

Awards and Honors

2017-2018, PRIDE Mentor Development Program, National Institute of Health and National Heart Lung and Blood Institute

2015, Mid-Career Minority Faculty Development Program, Association of American Medical Colleges (AAMC)

2014, Scientific Review Early Career Reviewer Awardee, National Institute of Health Center

2013, University of New Mexico Limited Competition Winner - Dana Foundation Neuroimaging Grant, University of New Mexico

2013, Junior Faculty Research Excellence Award Nominee, University of New Mexico

2013, Maternal-Fetal Medicine Awardee, National Institute of Child Health and Human Development (NICHD) conference

2012-2014, 2 year (PRIDE) Program to Increase Diversity in Behavioral Medicine Research Scholar, National Institute of Health and National Heart Lung and Blood Institute

2012, Junior Faculty Research Excellence Award Nominee, University of New Mexico

2012-2014, Selected for 1st University of New Mexico 2-year Medical Leadership Academy, University of New Mexico

2010-2011, Graduate Student of Excellence Award, University of New Mexico

2008, Travel Award, Pediatric Academic Societies' Conference

2007, Marshall Klaus Perinatal Research Award, American Academy of Pediatrics

2007, Fellow's Travel Award, American Academy of Pediatrics Section on Perinatal Pediatrics Conference

1999, National Medical Association Scholarship

1999, Mayo Clinic Summer Clinical Fellowship, Mayo Clinic

1999, Departmental Pediatric Scholar, Mayo Clinic

Editorial and Academic Positions

Editorial Positions

2018-present, Reviewer, Neonatology
2017-present, Reviewer, Health and Development
2016-present, Ad-hoc Reviewer, Cognition and Perception Study Section- National Institute of Child Health and Human Development
2011-present, Reviewer, Pediatrics
2011-present, Invited Abstract Reviewer, Pediatric Academic Society Annual Conference
2010-present, Reviewer, Archives of Pediatric and Adolescent Medicine
2010-present, Reviewer, Journal of Pediatrics
2009-present, Reviewer, Early Human Development

Leadership and Memberships

Memberships in Professional Organizations

2015-present, Society for Pediatric Research
2011-present, National Institute of Child Health and Human Development
 - 2011-present, Neonatal Research Network (NRN) Term Control Protocol Subcommittee
 - 2011-present, Neonatal Research Network (NRN) Follow-up Protocol Review Subcommittee
2003-present, American Academy of Pediatrics
 - 2016-present, Social Media Chair, MID Career Neonatologists (MidCaN), sub group of the Section on Neonatal-Perinatal Medicine
 - 2016-present, Mid- Career Neonatology Group Executive Council
 - 2015-present, Section on Neonatal- Perinatal Medicine Membership Committee
 - 2008-present, Section on Neonatal- Perinatal Medicine