Struan F.A. Grant, PhD

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Struan F.A. Grant, PhD, is the Co-Director of Center for Spatial and Functional Genomics, the Daniel B. Burke Endowed Chair for Diabetes Research and the Emeritus Associate Director of Center for Applied Genomics with the Children's Hospital of Philadelphia.

Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Background

Dr. Struan Grant has been conducting human genetics research for over 10 years. He has been on the faculty of the University of Pennsylvania Medical School since July 2007. The highlights of his career include the discovery of a mutation in a collagen gene which impacts bone density plus the identification of a major type 2 diabetes gene, with the latter receiving extensive media coverage including featuring on the front page of the New York Times. He has achieved these findings by working with key populations around the world that provide a unique insight into how to isolate human disease genes.

Dr Grant’s work primarily focuses on complex disease, specifically in relation to pediatrics. The isolation of genes in complex phenotypes in adults utilizing high-throughput genotyping technology has been impeded by interaction with strong environmental factors. Distillation of the genetic component in complex traits should be easier to determine in children, where the relatively short period of their lifetime limits the impact of environmental exposure. Given the global prevalence of diseases such as diabetes, obesity and osteoporosis, prevention of these disorders and their serious complications must be addressed in order to reduce individual morbidity and the economic burden on society. 

Education and Training

Additional Training

Wellcome Postdoctoral Studentship - Dept. of Medicine & Therapeutics, University of Aberdeen, Aberdeen, UK

Postdoctoral Research Officer - Garvan Institute of Medical Research, St. Vincent's Hospital, University of New South Wales, Sydney, Australia

Postdoctoral Scientist - Wellcome Trust Centre for Human Genetics, Oxford, UK

Undergraduate Degree

BSc in Genetics - University of Aberdeen, Aberdeen, UK

Graduate Degree

PHhD in Genetics - University of Aberdeen, Aberdeen, UK

Titles and Academic Titles

Co-Director, Center for Spatial and Functional Genomics

Associate Professor of Pediatrics in Genetics, Perelman School of Medicine at the University of Pennsylvania
Associate Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Publications

Papers

2017

S.E. McCormack, A. Chesi, J.A. Mitchell, S.M. Roy, D.L. Cousminer, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, S. Mahboubi, K.K. Winer, A. Kelly, S.F.A. Grant and B.S. Zemel: Relative skeletal maturation and population ancestry in non-obese children and adolescents. Journal of Bone and Mineral Research 32: 115-124, 2017.

R. Mishra*, A. Chesi*, D.L. Cousminer*, M.I. Hawa, J.P. Bradfield, K.M. Hodge, V.C. Guy, H. Hakonarson, BMDCS, D. Mauricio, N.C. Schloot, K.B. Yderstræde, B.F. Voight, S. Schwartz, B.O. Boehm*, R.D. Leslie* and S.F.A. Grant*: Relative Contribution of Type 1 Diabetes and Type 2 Diabetes Loci to the Genetic Etiology of Adult-Onset Non-Insulin Requiring Autoimmune Diabetes. BMC Medicine 15: 88, 2017 Notes: *equal contribution.

M.J. Redondo, S.F.A. Grant, A. Davis, C. Greenbaum and the T1D Exchange Biobank: Dissecting Heterogeneity in Pediatric Type 1 diabetes: Association of TCF7L2 rs7903146 TT and Low Risk HLA Genotypes. Diabetic Medicine 34: 286-290, 2017.

M.D. Gallagher, M. Posavi, P. Huang, T.L. Unger, Y. Berlyand, A.L. Gruenewald, A. Chesi, E. Manduchi, A.D. Wells, S.F.A. Grant, G.A. Blobel, C.D. Brown and A.S. Chen-Plotkin: A dementia-associated risk variant near TMEM106B alters chromatin architecture and gene expression. American Journal of Human Genetics In Press, 2017.

M.C.Y. Ng*, M. Graff*, Y. Lu, A.E. Justice, P. Mudgal, C.T. Liu, K. Young, L.R. Yanek, M.F. Feitosa, M.K. Wojczynski, K. Rand, J.A. Brody, B.E. Cade, L. Dimitrov, Q. Duan, X. Guo, L.A. Lange, M. Nalls, H. Okut, S.M. Tajuddin, B.O. Tayo, S. Vedantam, J.P. Bradfield, G. Chen, W.M. Chen, A. Chesi, M.R. Irvin, B. Padhukasahasram, J.A. Smith, W. Zheng, M.A. Allison, C.B. Ambrosone, E.V. Bandera, T.M. Bartz, S.I. Berndt, L. Bernstein, W.J. Blot, E.P. Bottinger, J. Carpten, S.J. Chanock, Y.D.I. Chen, D.V. Conti, R.S. Cooper, M. Fornage, B.I. Freedman, M. Garcia, P.J. Goodman, Y.H.H. Hsu, J. Hu, C.D. Huff, S.A. Ingles, E.M. John, R. Kittles, E. Klein, J. Li, B. McKnight, U. Nayak, B. Nemesure, A. Ogunniyi, A. Olshan, M. Press, R. Rohde, B.A. Rybicki, B. Salako, M. Sanderson, Y. Shao, D.S. Siscovick, J.L. Stanford, V.L. Stevens, A. Stram, S.S. Strom, D. Vaidya, J.S. Witte, J. Yao, X. Zhu, R.G. Ziegler, A. B. Zonderman, A. Adeyemo, S. Ambs, M. Cushman, J.D. Faul, H. Hakonarson, A.M. Levin, K.L. Nathanson, E.B. Ware, D.R. Weir, W. Zhao, D. Zhi, The Bone Mineral Density in Childhood Study (BMDCS) Group, D.K. Arnett, S.F.A. Grant, S.L.R. Kardia, O.I. Oloapde, D.C. Rao, C.N. Rotimi, M.M. Sale, L.K. Williams, B.S. Zemel, D.M. Becker, I.B. Borecki, M.K. Evans, T.B. Harris, J.N. Hirschhorn, Y. Li, S.R. Patel, B.M. Psaty, J.I. Rotter, J.G. Wilson, D.W. Bowden, L.A. Cupples, C.A. Haiman*, R.J.F. Loos*, and K.E. North*: Discovery and Fine-Mapping of Adiposity Loci Using High Density Imputation of Genome-Wide Association Studies in Individuals of African Ancestry: African Ancestry Anthropometry Genetics Consortium. PLoS Genetics 13: e1006719, 2017 Notes: *equal contribution.

J.L. Yellin, A. Trocle, S.F.A. Grant, H. Hakonarson, K.G. Shea and T.J. Ganley: Candidate Loci are Revealed by an Initial Genome-wide Association Study of Juvenile Osteochondritis Dissecans. Journal of Pediatric Orthopaedics 7: e32-e36, 2017.

G. Li*, J. Yin*, J. Fu, L. Li, S.F.A. Grant, C. Li, M. Li, J. Mi, M. Li and S. Gao: FGF21 deficiency is associated with childhood obesity, insulin resistance and hypoadiponectinaemia: The BCAMS Study. Diabetes and Metabolism 43: 253-260, 2017 Notes: *equal contribution.

D. Manousaki*, T. Dudding*, S. Haworth*, Y.H. Hsu*, C.T. Liu*, C. Medina-Gómez*, T. Voortman*, N. van der Velde*, H. Melhus*, C. Robinson-Cohen*, D.L. Cousminer*, M. Nethander*, L. Vandenput*, R. Noordam*, V. Forgetta, C.M.T. Greenwood, M.L. Biggs, B.M. Psaty, J.I. Rotter, B.S. Zemel, J.A. Mitchell, B. Taylor, M. Lorentzon, M. Karlsson, V.V.W. Jaddoe, H. Tiemeier, N. Campos-Obando, O.H. Franco, A.G. Utterlinden, L. Broer, N.M. van Schoor, A.C. Ham, M. Arfan Ikram, D. Karasik, R. de Mutsert, F.R. Rosendaal, M. den Heijer, T.J. Wang, L. Lind*, E.S. Orwoll*, D.O. Mook-Kanamori*, K. Michaëlsson*, B. Kestenbaum*, C. Ohlsson*, D. Mellström*, L.C.P.G.M. de Groot*, S.F.A. Grant*, D.P. Kiel*, M.C. Zillikens*, F. Rivadeneira*, S. Sawcer*, N.J. Timpson* and J.B. Richards*: Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis. American Journal of Human Genetics 101: 227-238, 2017 Notes: *equal contribution.

C. Medina Gomez*, J.P. Kemp*, N. L. Dimou, E. Kreiner, A. Chesi, B.S. Zemel, K. Bønnelykke, C.G. Boer, T.S. Ahluwalia, H. Bisgaard, E. Evangelou, D.H.M. Heppe, L.F. Bonewald, J.P. Gorski, M. Ghanbari, S. Demissie, G. Duque, M.T. Maurano, D.P. Kiel, Y.H. Hsu, B.C.J. van der Eerden, C. Ackert-Bicknell, S. Reppe, K.M. Gautvik, T. Raastad, D. Karasik, J. van de Peppel, V.W.V. Jaddoe, A.G. Uitterlinden, J.H. Tobias, S.F.A. Grant, P.G. Bagos, D.M. Evans* and F. Rivadeneira*: Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus. Nature Communications 8: 121, 2017 Notes: *equal contribution.

A. Hinney, M. Kesselmeier, S. Jall, A.L. Volckmar, M. Föcker, J. Antel, GCAN, WTCCC, I.M. Heid, T.W. Winkler, GIANT, S.F.A. Grant, EGG, Y. Guo, A.W. Bergen, W. Kaye, W. Berrettini, H. Hakonarson, Price Foundation Collaborative Group, Children's Hospital of Philadelphia/Price Foundation, B. Herpertz-Dahlmann, M. de Zwaan, W. Herzog, S. Ehrlich, S. Zipfel, K.M. Egberts, R. Adan, M. Brandys, A.Marie van Elburg, V.B. Perica, C.S. Franklin, M.H. Tschöp, E. Zeggini, C. Bulik, D. Collier, A. Scherag, T.D. Müller and J. Hebebrand: Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index. Molecular Psychiatry 22: 192-201, 2017.

A. Chesi, J.A. Mitchell, H.J. Kalkwarf, J.P. Bradfield, J.M. Lappe, D.L. Cousminer, S.M. Roy, S.E. McCormack, V. Gilsanz, S.E. Oberfield, H. Hakonarson, J.A. Shepherd, A. Kelly, B.S. Zemel* and S.F.A. Grant*: A Genome-Wide Association Study Identifies Two Sex-specific Loci, at SPTB and IZUMO3, Influencing Pediatric Bone Mineral Density at Multiple Skeletal Sites. Journal of Bone and Mineral Research 32: 1274-1281, 2017 Notes: *equal contribution.

G.P. Way, D.W. Youngstrom, K.D. Hankenson, C.S. Greene* and S.F.A. Grant*: Implicating candidate genes at GWAS signals by leveraging topologically associating domains. European Journal of Human Genetics Epub ahead of print, August 2017 Notes: *equal contribution.

S.E. McCormack, D.L. Cousminer, A. Chesi, J.A. Mitchell, S.M. Roy, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, K.K. Winer, A. Kelly, S.F.A. Grant and B.S. Zemel: Association Between Linear Growth and Bone Accrual in a Diverse Cohort of Children and Adolescents. JAMA Pediatrics Epub ahead of print, July 2017.

Q. Xia*, S. Lu1*, J. Ostrovsky, S.E. McCormack, M.J. Falk and S.F.A. Grant: PARP-1 inhibition rescues short lifespan in hyperglycemic C. elegans and improves GLP-1 secretion in human cells. Aging and Disease Epub ahead of print, March 2017 Notes: *equal contribution.

L. Li, J. Fu, X.T. Yu, G. Li, L. Xu, J. Yin, H. Cheng, D. Hou, X. Zhao, S. Gao, W. Li, C. Li, S.F.A. Grant, M. Li, Y. Xiao, J. Mi* and M. Li*: Sleep Duration and Cardiometabolic Risk Among Chinese School-aged Children: Do Adipokines Play a Mediating Role? Sleep Epub ahead of print, March 2017 Notes: *equal contribution.

2016

S.M. Roy, J.G. Spivack, M.S. Faith, A. Chesi, J.A. Mitchell, A. Kelly, S.F.A. Grant, S.E. McCormack* and B.S. Zemel*: Infant BMI or Weight-for-Length and Obesity Risk in Early Childhood. Pediatrics 137: e20153492, 2016 Notes: *equal contribution.

Q. Xia*, A. Chesi*, E. Manduchi*, B.T. Johnston, S. Lu, M.E. Leonard, U.W. Parlin, E.F. Rappaport, P. Huang, A.D. Wells, G.A. Blobel, M.E. Johnson* and S.F.A. Grant*: The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5. Diabetologia 59: 2360-2368, 2016 Notes: *equal contribution; (Accompanying Commentary PMID:27623948).

M. Bustamante*, M. Standl*, Q. Bassat, N. Vilor-Tejedor, C. Medina-Gomez, C. Bonilla, T.S. Ahluwalia, J. Bacelis, J.P. Bradfield, C.M.T. Tiesler, F. Rivadeneira, S. Ring, N.H. Vissing, N.R. Fink, A. Jugessur, F.D. Mentch, F. Ballester, J. Kriebel, J.C. Kiefte-de Jong, H.M. Wolsk, S. Llop, E. Thiering, S.A. Beth, N.J. Timpson, J. Andersen, Holger Schulz, V.W.V. Jaddoe, D.M. Evans, J. Waage, H. Hakonarson, S.F.A. Grant, B. Jacobsson, K. Bønnelykke, H. Bisgaard, G. Davey Smith, H.A. Moll, J. Heinrich, X. Estivill* and J. Sunyer*: A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways. Human Molecular Genetics 25: 4127-4142, 2016 Notes: *equal contribution.

L. Li, J. Yin, H. Cheng, Y. Wang, S. Gao, Mi. Li, S.F.A. Grant, C. Li, J. Mi* and M. Li*: Identification of genetic and environmental factors predicting metabolically healthy obesity in children: Data from the BCAMS study. Journal of Clinical Endocrinology and Metabolism 101: 1816-25, 2016 Notes: *equal contribution.

K.L. Young, M. Graff, K.E. North, A. Richardson, J.P. Bradfield, S.F.A. Grant, L.A. Lange, E.M. Lange, K.M. Harris and P. Gordon-Larsen: Influence of SNP*SNP interaction on BMI in European American Adolescents: Findings from the National Longitudinal Study of Adolescent Health. Pediatric Obesity 11: 95-101, 2016.

J.M. Lane*, A.M. Chang*, A.C. Bjonnes, D. Aeschbach, C. Anderson, B.E. Cade, S.W. Cain, C.A. Czeisler, S.A. Gharib, J.J. Gooley, D.J. Gottlieb, S.F.A. Grant, E.B. Klerman, D.S. Lauderdale, S.W. Lockley, M.Munch, S. Patel, N.M. Punjabi, R.W. Shantakumar, M. Rueger, M.A. St. Hilaire, N. Santhi, K. Scheuermaier, E. Van Reen, P.C. Zee, S.A. Shea, J.F. Duffy, O.M. Buxton, S. Redline, F.A.J.L. Scheer* and R. Saxena*: Impact of common diabetes risk variant in MTNR1B on sleep, circadian and melatonin physiology. Diabetes 65: 1741-1751, 2016.

J.F. Felix*, J.P. Bradfield*, C. Monnereau*, R.J.P. van der Valk*, E. Stergiakouli, A. Chesi, R. Gaillard, B. Feenstra, E. Thiering, E. Kreiner-Møller, A. Mahajan, N. Pitkänen, R. Joro, A. Cavadino, V. Huikari, S. Franks, M.M. Groen-Blokhuis, D.L. Cousminer, J.A. Marsh, T. Lehtimäki, J.A. Curtin, J. Vioque, T.S. Ahluwalia, R. Myhre, T.S. Price, N. Vilor-Tejedor, L. Yengo, N. Grarup, I. Ntalla, W. Ang, M. Atalay, H. Bisgaard, A.I. Blakemore, A. Bonnefond, L. Carstensen, Bone Mineral Density in Childhood Study (BMDCS) Consortium, Early Genetics and Lifecourse Epidemiology (EAGLE) consortium, J. Eriksson, C. Flexeder, L. Franke, F. Geller, M. Geserick, A.L. Hartikainen, C.M. A. Haworth, J.N. Hirschhorn, A. Hofman, J.C. Holm, M. Horikoshi, J.J. Hottenga, J. Huang, H.N. Kadarmideen, M. Kähönen, W. Kiess, H.M. Lakka, T.A. Lakka, A.M. Lewin, L. Liang, L.P. Lyytikäinen, B. Ma, P. Magnus, S.E. McCormack, G. McMahon, F.D. Mentch, C.M. Middeldorp, C.S. Murray, K. Pahkala, T.H. Pers, R. Pfäffle, D.S. Postma, C. Power, A. Simpson, V. Sengpiel, C.M.T. Tiesler, M. Torrent, A.G. Uitterlinden, J.B. van Meurs, R. Vinding, J. Waage, J. Wardle, E. Zeggini, B.S. Zemel, G.V. Dedoussis, O. Pedersen, P. Froguel, J. Sunyer, R. Plomin, B. Jacobsson, T. Hansen, J.R. Gonzalez, A. Custovic, O.T. Raitakari, C.E. Pennell, E. Widén, D.I. Boomsma, G.H. Koppelman, S. Sebert, M.R. Järvelin, E. Hyppönen, M.I. McCarthy, V. Lindi, N. Harri, A. Körner, K. Bønnelykke, J. Heinrich, M. Melbye, F. Rivadeneira, H. Hakonarson, S.M. Ring, G. Davey Smith, T.I.A. Sørensen, N.J. Timpson*, S.F.A. Grant* and Vincent W.V. Jaddoe* for the Early Growth Genetics (EGG) Consortium: Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Human Molecular Genetics 25: 389-403, 2016 Notes: *equal contribution.

J.A. Mitchell, A. Chesi, O. Elci, S.E. McCormack, S.M. Roy, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, S.F.A. Grant* and B.S. Zemel*: Genetic Risk Scores Implicated in Adult Bone Fragility Associate With Pediatric Bone Density. Journal of Bone and Mineral Research 31: 789-95, 2016 Notes: *equal contribution.

J.A. Mitchell, A. Chesi, O. Elci, S.E. McCormack, S.M. Roy, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, S.F.A. Grant* and B.S. Zemel*: Physical activity benefits the skeleton of children genetically predisposed to lower bone density in adulthood. Journal of Bone and Mineral Research 31: 1504-12, 2016 Notes: *equal contribution.

J.A. Mitchell*, A. Chesi*, S.E. McCormack, S.M. Roy, D.L. Cousminer, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, B.S. Zemel* and S.F.A. Grant*: Rare EN1 variants and pediatric bone mass. Journal of Bone and Mineral Research 31: 1513-7, 2016 Notes: *equal contribution.

J. Tyrrell, R.C. Richmond, T.M. Palmer, B. Feenstra, J. Rangarajan, S. Metrustry, A. Cavadino, L. Paternoster, L.L. Armstrong, N.M.G. De Silva, A.R. Wood, M. Horikoshi, F. Geller, R. Myhre, J.P. Bradfield, E. Kreiner-Møller, V. Huikari, J.N. Painter, J.J. Hottenga, C. Allard, D.J. Berry, L. Bouchard, S. Das, D.M. Evans, H. Hakonarson, M.G. Hayes, J. Heikkinen, A. Hofman, B. Knight, P.A. Lind, M.I. McCarthy, G. McMahon, S.E. Medland, M. Melbye, A.P. Morris, M. Nodzenski, C. Reichetzeder, S.M. Ring, S. Sebert, V. Sengpiel, T.I.A. Sørensen, G. Willemsen, E.J.C. de Geus, N.G. Martin, T.D. Spector, C. Power, M.R. Järvelin, H. Bisgaard, S.F.A. Grant, E.A. Nohr, V.W. Jaddoe, B. Jacobsson, J.C. Murray, B. Hocher, A.T. Hattersley, D.M. Scholtens, G. Davey Smith, M.F. Hivert, J.F. Felix, E. Hyppönen, W.L. Lowe Jr, T.M. Frayling*, D.A. Lawlor* and R.M. Freathy* for the Early Growth Genetics (EGG) Consortium: Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight. JAMA 315: 1129-1140, 2016 Notes: *equal contribution.

Early Growth Genetics Consortium: Genome-wide associations for birth weight and correlations with adult disease. Nature 538: 248-252, 2016.

D.L. Cousminer, A. Arkader, B.F. Voight, M. Pacifici and S.F.A. Grant: Assessing the general population frequency of rare coding variants in the EXT1 and EXT2 genes previously implicated in Hereditary Multiple Exostoses. Bone 92: 196-200, 2016.

B.P. Prins*, A. Abbasi*, A. Wong*, A. Vaez*, I. Nolte, N. Franceschini, P.E. Stuart, J. Guterriez Achury, V. Mistry, J.P. Bradfield, A.M. Valdes, A. Shatunov, PAGE Consortium, International Stroke Genetics Consortium, Systemic Sclerosis consortium, Treat OA consortium, DIAGRAM Consortium, CARDIoGRAMplusC4D Consortium, ALS consortium, International Parkinson's Disease Genomics Consortium, Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, CKDGen consortium, GERAD1 Consortium, International Consortium for Blood Pressure, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Inflammation Working Group of the CHARGE Consortium, C. Lu, B. Han, S. Raychaudhuri, S. Bevan, M.D. Mayes, L.C. Tsoi, E. Evangelou, R.P. Nair, S.F.A. Grant, C. Polychronakos, T.R.D. Radstake, D.A. van Heel, M.L. Dunstan, N.W. Wood, A. Al-Chalabi, A. Dehghan, H. Hakonarson, H.S. Markus, J.T. Elder, J. Knight, D.E. Arking, T.D. Spector, B.P.C. Koeleman, C.M. van Duijn, J. Martin, A.P. Morris, R.K. Weersma, C. Wijmenga, P.B. Munroe, J.R.B. Perry, J.G. Pouget, Y. Jamshidi, H. Snieder and B.Z. Alizadeh: Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study. PLoS Medicine 13: e1001976, 2016 Notes: *equal contribution.

2015

Y.R. Li, S.D. Zhao, J. Li, J.P. Bradfield, M. Mohebnasab, L. Steel, J. Kobie, D.J. Abrams, F.D. Mentch, J.T. Glessner, Y. Guo, Z. Wei, J.J. Connolly, C.J. Cardinale, M. Bakay, D. Li, S.M. Maggadottir, K.A. Thomas, H. Qui, R.M. Chiavacci, C.E. Kim, F. Wang, J. Snyder, B. Flatø, Ø. Førre, L.A. Denson, S.D. Thompson, M.L. Becker, S.L. Guthery, A. Latiano, E. Perez, E. Resnick, C. Strisciuglio, A. Staiano, E. Miele, M.S. Silverberg, B.A. Lie, M. Punaro, R.K. Russell, D.C Wilson, M.C. Dubinsky, D.S. Monos, V. Annese, J.E. Munro, C. Wise, H. Chapel, C. Cunningham-Rundles, J.S. Orange, E.M. Behrens, K.E. Sullivan, S. Kugathasan, A.M. Griffiths, J. Satsangi, S.F.A. Grant, P.M.A. Sleiman, T. Finkel, C. Polychronakos, R.N. Baldassano, E.T. Luning Prak, J.A. Ellis, H. Li, B.J. Keating and H. Hakonarson: Genetic sharing and heritability of paediatric age of onset autoimmune diseases. Nature Communications 6: 8442, 2015.

Y.R. Li, J. Li, S.D. Zhao, J.P. Bradfield, F.D. Mentch, S.M. Maggadottir, C. Hou, D.J. Abrams, D. Chang, F. Gao, Y. Guo, Z. Wei, J.J. Connolly, C.J. Cardinale, M. Bakay, J.T. Glessner, D. Li, C. Kao, K.A. Thomas, H. Qiu, R.M. Chiavacci, C.E. Kim, F. Wang, J. Snyder, M.D. Richie, B. Flatø, Ø. Førre, L.A. Denson, S.D. Thompson, M.L. Becker, S.L. Guthery, A. Latiano, E. Perez, E. Resnick, R.K. Russell, D.C Wilson, M.S. Silverberg, V. Annese, B.A. Lie, M. Punaro, M.C. Dubinsky, D.S. Monos, C. Strisciuglio, A. Staiano, E. Miele, S. Kugathasan, J.A. Ellis, J.E. Munro, K.E. Sullivan, C. Wise, H. Chapel, C. Cunningham-Rundles, S.F.A. Grant, J.S. Orange, P.M.A. Sleiman, E.M. Behrens, A.M. Griffiths, J. Satsangi, T.H. Finkel, A. Keinan, E.T. Luning Prak, C. Polychronakos, R.N. Baldassano, H. Li, B.J. Keating and H. Hakonarson: Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. Nature Medicine 21: 1018-27, 2015.

Y. Chen*, C. Chen*, Z. Zhang, C.C. Liu, M.E. Johnson, C.A. Espinoza, L.E. Edsall, B. Ren, X.J. Zhou, S.F.A. Grant, A.D. Wells* and L. Chen*: DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions. Nucleic Acids Research 43: 1268-1282, 2015 Notes: *equal contribution.

W.D. Li*, H. Jiao*, K. Wang*, F. Yang, S.F.A. Grant, H. Hakonarson, R. Ahima and R.A. Price: Pathway-Based Genome-wide Association Studies Reveal That the Rac1 Pathway Is Associated with Plasma Adiponectin Levels. Scientific Reports 5: 13422, 2015 Notes: *equal contribution.

S.M. Roy, A. Chesi, F. Mentch, R. Xiao, R. Chiavacci, J.A. Mitchell, A. Kelly, H. Hakonarson, S.F.A. Grant, B.S. Zemel and S.E. McCormack: Body Mass Index (BMI) Trajectories in Infancy Differ by Population Ancestry and May Presage Disparities in Early Childhood Obesity. Journal of Clinical Endocrinology and Metabolism 100: 1551-60, 2015.

R.J.P. van der Valk*, E. Kreiner-Møller*, M.N. Kooijman*, M. Guxens*, E. Stergiakouli*, A. Sääf, J.P. Bradfield, F. Geller, M.G. Hayes, D.L. Cousminer, A. Körner, E. Thiering, J.A. Curtin, R. Myhre, V. Huikari, R. Joro, M. Kerkhof, N.M. Warrington, N. Pitkänen, I. Ntalla, M. Horikoshi, R. Veijola, R.M. Freathy, Y.Y. Teo, S.J. Barton, D.M. Evans, J.P. Kemp, B. St Pourcain, S.M. Ring, G. Davey Smith, A. Bergström, I. Kull, H. Hakonarson, F.D. Mentch, H. Bisgaard, B. Chawes, J. Stokholm, J. Waage, P. Eriksen, A. Sevelsted, M. Melbye, Early Genetics & Lifecourse Epidemiology (EAGLE) Consortium, C.M. van Duijn, C. Medina-Gomez, A. Hofman, J.C. de Jongste, H.R. Taal, A.G. Uitterlinden, Genetic Investigation of ANthropometric Traits (GIANT) Consortium, L.L. Armstrong, J. Eriksson, A. Palotie, M. Bustamante, X. Estivill, J.R. Gonzalez, S. Llop, W. Kiess, A. Mahajan, C. Flexeder, C.M.T. Tiesler, C.S. Murray, A. Simpson, P. Magnus, V. Sengpiel, A.L. Hartikainen, S. Keinanen-Kiukaanniemi, A. Lewin, A. Da Silva Couto Alves, A.I. Blakemore, J.L. Buxton, M. Kaakinen, A. Rodriguez, S. Sebert, M. Vaarasmaki, T. Lakka, V. Lindi, U. Gehring, D.S. Postma, W. Ang, J.P. Newnham, L.P. Lyytikäinen, K. Pahkala, O.T. Raitakari, K. Panoutsopoulou, E. Zeggini, D.I. Boomsma, M. Groen-Blokhuis, J. Ilonen, L. Franke, J.N. Hirschhorn, T.H. Pers, L. Liang, J. Huang, B. Hocher, M. Knip, S.M. Saw, J.W. Holloway, E. Melén, S.F.A. Grant, B. Feenstra, W.L. Lowe, E. Widén, E. Sergeyev, H. Grallert, A. Custovic, B. Jacobsson, M.R. Jarvelin, M. Atalay, G.H. Koppelman, C.E. Pennell, H. Niinikoski, G.V. Dedoussis, M.I. McCarthy, T.M. Frayling, J. Sunyer*, N.J. Timpson*, F. Rivadeneira*, K. Bønnelykke* and V.W.V. Jaddoe* for the Early Growth Genetics (EGG) Consortium: A novel common variant in DCST2 is associated with length in early life and height in adulthood. Human Molecular Genetics 24: 1155-1168, 2015 Notes: *equal contribution.

Q. Xia, S. Deliard, C.X. Yuan, M.E. Johnson and S.F.A. Grant: Characterization of the transcriptional machinery bound across the widely presumed type 2 diabetes causal variant, rs7903146, within TCF7L2. European Journal of Human Genetics 23: 103-109, 2015 Notes: Featured article.

P.K. Joshi*, T. Esko*, H. Mattsson, N. Eklund, I. Gandin, T. Nutile, A.U. Jackson, C. Schurmann, A.V. Smith, W. Zhang, Y. Okada, A. Stancáková, J.D. Faul, W. Zhao, T.M. Bartz, M. Pina Concas, N. Franceschini, S. Enroth, V. Vitart, S. Trompet, X. Guo, D.I. Chasman, J.R. O'Connel, T. Corre, S.S. Nongmaithem, Y. Chen, M. Mangino, D. Ruggiero, M. Traglia, A.E. Farmaki, T. Kacprowski, A. Bjonnes, A. van der Spek, Y. Wu, A.K. Giri, L.R. Yanek, L. Wang, E. Hofer, C.A. Rietveld, O. McLeod, M.C. Cornelis, C. Pattaro, N. Verweij, C. Baumbach, A. Abdellaoui, H.R. Warren, D. Vuckovic, H. Mei, C. Bouchard, J.R.B. Perry, S. Cappellani, S.S. Mirza, M.C. Benton, U. Broeckel, S.E. Medland, P.A. Lind, G. Malerba, A. Drong, L. Yengo, L.F. Bielak, D. Zhi, P.J. van der Most, D. Shriner, R. Mägi, G. Hemani, T. Karaderi, Z. Wang, T. Liu, I. Demuth, J. Hua Zhao, W. Meng, L. Lataniotis, S.W. van der Laan, J.P. Bradfield, A.R. Wood, A. Bonnefond, T.S. Ahluwalia, L.M. Hall, E. Salvi, S. Yazar, L. Carstensen, H.G. de Haan, M. Abney, U. Afzal, M.A. Allison, N. Amin, F.W. Asselbergs, ..., X. Zhu, The BioBank Japan Project, R.M. Salem, M. Melbye, H. Bisgaard, N.J. Samani, D. Cusi, D.A. Mackey, R.S. Cooper, P. Froguel, G. Pasterkamp, S.F.A. Grant, H. Hakonarson, L. Ferrucci, R.A. Scott, A.D. Morris, C.N.A. Palmer, G. Dedoussis, P. Deloukas, L. Bertram, U. Lindenberger, S.I. Berndt, C.M. Lindgren, N.J. Timpson, A. Tönjes, P.B. Munroe, T.I.A. Sørensen, C.N. Rotimi, D.K. Arnett, A.J. Oldehinkel, S.L.R. Kardia, B. Balkau, G. Gambaro, A.P. Morris, J.G. Eriksson, M.J. Wright, N.G. Martin, S.C. Hunt, J.M. Starr, I.J. Deary, L.R. Griffiths, H. Tiemeier, N. Pirastu, J. Kaprio, N.J. Wareham, L. Pérusse, J.G. Wilson, G. Girotto, M.J. Caulfield, O. Raitakari, D.I. Boomsma, C. Gieger, P. van der Harst, A.A. Hicks, P. Kraft, J. Sinisalo, P. Knekt, M. Johannesson, P.K.E. Magnusson, A. Hamsten, R. Schmidt, I.B. Borecki, E. Vartiainen, D.M. Becker, D. Bharadwaj, K.L. Mohlke, M. Boehnke, C.M. van Duijn, D.K. Sanghera, A. Teumer, E. Zeggini, A. Metspalu, P. Gasparini, S. Ulivi, C. Ober, D. Toniolo, I. Rudan, D.J. Porteous, M. Ciullo, T.D. Spector, C. Hayward, J. Dupuis, R.J.F. Loos, A.F. Wright, G.R. Chandak, P. Vollenweider, A. Shuldiner, P.M. Ridker, J.I. Rotter, N. Sattar, U. Gyllensten, K.E. North, M. Pirastu, B.M. Psaty, D.R. Weir, M. Laakso, V. Gudnason, A. Takahashi, J.C. Chambers, J.S. Kooner, D.P. Strachan, H. Campbell, J.N. Hirschhorn, M. Perola, O. PolaÅ¡ek*, J.F. Wilson* for ROHgen: Directional dominance on stature and cognition in diverse human populations. Nature 523: 459-62, 2015.

K.T. Nead, A. Li, M.R. Wehner, B. Neupane, S. Gustafsson, A. Butterworth, J.C. Engert, A.D. Davis, R.A. Hegele, R. Miller, M. den Hoed, K.T. Khaw, T.O. Kilpeläinen, N. Wareham, T.L. Edwards, G. Hallmans, T.V. Varga, S.L.R. Kardia, J.A. Smith, W. Zhao, J.D. Faul, D. Weir, J. Mi, B. Xi, S. Canizales Quinteros, C. Cooper, A. Aihie Sayer, K. Jameson, A. Grøntved, M. Fornage, S. Sidney, C.L. Hanis, H.M. Highland, H.U. Häring, M. Heni, J. Lasky-Su, S.T. Weiss, G.S. Gerhard, C. Still, M.M. Melka, Z. Pausova, T. Paus, S.F.A. Grant, H. Hakonarson, R.A. Price, K. Wang, A. Scherag, J. Hebebrand, A. Hinney, BioBank Japan, AGEN-BMI, GIANT Consortium, P.W. Franks, T.M. Frayling, M.I. McCarthy, J.N. Hirschhorn, R. Loos, E. Ingelsson, H.C. Gerstein, S. Yusuf, J. Beyene, S.S. Anand and D. Meyre: Contribution of common non-synonymous variants in PCSK1 to body-mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331,175 individuals. Human Molecular Genetics 24: 3582-94, 2015.

J.A. Mitchell, A. Chesi, O. Elci, S.E. McCormack, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, B.S. Zemel* and S.F.A. Grant*: Genetics of bone mass in childhood and adolescence: effects of sex and maturation interactions. Journal of Bone and Mineral Research 30: 1676-83, 2015 Notes: *equal contribution.

H. Jiao, K. Wang, F. Yang, S.F.A. Grant, H. Hakonarson, R.A. Price and W.D. Li: Pathway-based genome-wide association studies for plasma triglycerides in obese females and normal-weight controls. PLoS ONE 10: e0134923, 2015.

F. Sgariglia, Elena Pedrini, J.P. Bradfield, T.R. Bhatti, P. D'Adamo, J.P. Dormans, A.T. Gunawardena, H. Hakonarson, J.T. Hecht, L. Sangiorgi, M. Pacifici*, M. Enomoto-Iwamoto* and S.F.A. Grant*: The Type 2 Diabetes associated rs7903146 T allele within TCF7L2 is significantly under-represented in Hereditary Multiple Exostoses: Insights into pathogenesis. Bone 72: 123-127, 2015 Notes: *equal contribution.

C. Medina-Gómez, A. Chesi, D.H.M. Heppe, B.S. Zemel, J.L. Yin, H.J. Kalkwarf, A. Hofman, J.M. Lappe, A. Kelly, M. Kayser, S.E. Oberfield, V. Gilsanz, A.G. Uitterlinden, J.A. Shepherd, V.W.V. Jaddoe, S.F.A. Grant, O. Lao* and F. Rivadeneira*: BMD Loci Contribute to Ethnic And Developmental Differences in Skeletal Fragility Across Populations: Assessment of Evolutionary Selection Pressures. Molecular Biology and Evolution 32: 2961-72, 2015 Notes: *equal contribution.

A. Chesi, J.A. Mitchell, H.J. Kalkwarf, J.P. Bradfield, J.M. Lappe, S.E. McCormack, V. Gilsanz, S.E. Oberfield, H. Hakonarson, J.A. Shepherd, A. Kelly, B.S. Zemel* and S.F.A. Grant*: A trans-ethnic genome-wide association study identifies gender-specific loci influencing pediatric aBMD and BMC at the distal radius. Human Molecular Genetics 24: 5053-9, 2015 Notes: *equal contribution.

2014

M.T. Purkey*, J. Li*, F. Mentch, S.F.A. Grant, M. Desrosiers, H. Hakonarson and E. Toskala: Genetic Variation in Genes Encoding Airway Epithelial Potassium Channels Is Associated with Chronic Rhinosinusitis in a Pediatric Population. PLoS ONE 9: e89329, 2014 Notes: *equal contribution.

M.J. Redondo, J. Muniz, L.M. Rodriguez, D. Iyer, F. Vaziri-Sani, M.W. Haymond, C.S. Hampe, M.L. Metzker, S.F.A. Grant and A. Balasubramanyam: Association of TCF7L2 variation with single islet autoantibody expression in children with type 1 diabetes. BMJ Open Diabetes Research & Care 2: e000008, 2014.

M.F. Keller*, A.P. Reiner*, Y. Okada*, F.J.A. van Rooij*, A.D. Johnson, M.H. Chen, A.V. Smith, A.P. Morris, T. Tanaka, L. Ferrucci, A.B. Zonderman, G. Lettre, T. Harris, M. Garcia, S. Bandinelli, R. Qayyum, L.R. Yanek, D.M. Becker, L.C. Becker, C. Kooperberg, B. Keating, J. Reis, H. Tang, E. Boerwinkle, Y. Kamatani, K. Matsuda, N. Kamatani, Y. Nakamura, M. Kubo, S. Liu, A. Dehghan, J.F. Felix, A. Hofman, A.G. Uitterlinden, C.M. van Duijn, O.H. Franco, D.L. Longo, A.B. Singleton, B.M. Psaty, M.K. Evans, L.A. Cupples, J.I. Rotter, C.J. O'Donnell, A. Takahashi*, J.G. Wilson*, S.K. Ganesh* and M.A. Nalls* for the CHARGE Hematology, COGENT [of which S.F.A. Grant is a member] and BioBank Japan Project (RIKEN) Working Groups: Trans-ethnic meta-analysis of white blood cell phenotypes. Human Molecular Genetics 23: 6944-60, 2014 Notes: *equal contribution.

M.E. Johnson, S. Deliard, F. Zhu, Q. Xia, A.D. Wells, K.D. Hankenson and S.F.A. Grant: A ChIP-seq defined genome-wide map of MEF2C binding reveals inflammatory pathways associated with its role in bone density determination. Calcified Tissue International 94: 396-402, 2014.

M.E. Johnson, J. Schug, A.D. Wells, K.H. Kaestner and S.F.A. Grant: Genome-wide analyses of ChIP-seq derived FOXA2 DNA occupancy in liver points to genetic networks underpinning multiple complex traits. Journal of Clinical Endocrinology and Metabolism 99: E1580-5, 2014.

M.E. Johnson*, J. Zhao*, J. Schug, S. Deliard, Q. Xia, V.C. Guy, J. Sainz, K.H. Kaestner, A.D. Wells and S.F.A. Grant: Two novel type 2 diabetes loci revealed through integration of TCF7L2 DNA occupancy and SNP association data. BMJ Open Diabetes Research & Care 2: e000052, 2014 Notes: 'Editor's Choice'; *equal contribution.

D.L. Cousminer, E. Stergiakouli, D.J. Berry, W. Ang, M.M. Groen-Blokhuis, A. Körner, N. Siitonen, I. Ntalla, M. Marinelli, J.R.B. Perry, J. Kettunen, R. Jansen, I. Surakka, N.J. Timpson, S. Ring, G. McMahon, C. Power, C. Wang, M. Kähönen, J. Viikari, T. Lehtimäki, C.M. Middeldorp, H.E. Hulshoff Pol, M. Neef, S. Weise, K. Pahkala, H. Niinikoski E. Zeggini, K. Panoutsopoulou, M. Bustamante, B.W.J.H. Penninx, the ReproGen Consortium, J. Murabito, M. Torrent, G.V. Dedoussis, W. Kiess, D.I. Boomsma, C.E. Pennell, O.T. Raitakari, E. Hyppönen, G. Davey Smith, S. Ripatti, M.I. McCarthy and E. Widén for the Early Growth Genetics (EGG) Consortium [of which S.F.A. Grant is a member]: Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Human Molecular Genetics 23: 4452-64, 2014.

D.J. Sartori, C.J. Wilbur, S. Long, C. Li, J.P. Bradfield, H. Hakonarson, S.F.A. Grant, W.T. Pu and J.A. Kushner: GATA Factors Promote ER Integrity and β-Cell Survival and Contribute to Type 1 Diabetes Risk. Molecular Endocrinology 28: 28-39, 2014.

D. Londono*, I. Kou*, T.A. Johnson*, S. Sharma*, Y. Ogura, T. Tsunoda, A. Takahashi, M. Matsumoto, J.A. Herring, T.P. Lam, X. Wang, E.M.S. Tam, Y.Q. Song, Y.H. Fan, D. Chan, K.S.E. Cheah, X. Qiu, H. Jiang, D. Huang, Japanese Scoliosis Clinical Research Group, TSRHC IS Clinical Group, the International Consortium for Scoliosis Genetics [of which S.F.A. Grant is a member], P. Su, P. Sham, K.M.C. Cheung, K.D.K. Luk, D. Gordon, Y. Qiu, J. Cheng, N. Tang, S. Ikegawa and C.A. Wise: A meta-analysis identifies adolescent idiopathic scoliosis association with LBX1 locus in multiple ethnic groups. Journal of Medical Genetics 51: 401-406, 2014 Notes: *equal contribution.

C.T. Liu, M.L. Buchkovich, T.W. Winkler, I.M. Heid, African Ancestry Anthropometry Genetics Consortium[of which S.F.A. Grant is a member], GIANT Consortium, I. Borecki, C.S. Fox, K.L. Mohlke, K.E. North and L.A. Cupples: Multi-ethnic Fine-mapping of 14 Central Adiposity Loci. Human Molecular Genetics 23: 4738-44, 2014.

C.J. Cardinale*, Z. Wei*, J. Li, J. Zhu, R.N. Baldassano, S.F.A. Grant and H. Hakonarson: Transcriptome Profiling of Human Ulcerative Colitis Mucosa Reveals Altered Expression of Pathways Enriched in Genetic Susceptibility Loci. PLoS ONE 9: e96153, 2014.

A. Tare, J.M. Lane, B.E. Cade, S.F.A. Grant, T. Chen, N.M. Punjabi, D.S. Lauderdale, P.C. Zee, S.A. Gharib, D.J. Gottlieb, F.A.J.L. Scheer, S. Redline and R. Saxena: Sleep duration does not mediate or modify association of common genetic variants with type 2 diabetes. Diabetologia 57: 339-46, 2014.

2013

Y. Guo, M.B. Lanktree, K.C. Taylor, H. Hakonsarson, L.A. Lange, B.J. Keating, The IBC 50K SNP array BMI Consortium [of which S.F.A. Grant is a member]: Gene‐centric meta‐analyses of 108,912 individuals confirm known body mass index loci and reveal three novel signals. Human Molecular Genetics 22: 184-201, 2013.

W.D. Li, H. Jiao, K. Wang, C. Zhang, J.T Glessner, S.F.A. Grant, H. Zhao, H. Hakonarson and R.A. Price: A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls. Obesity 21: E490-E494, 2013.

T.L. Yang, Y. Guo, H. Shen, J. Li, J.T. Glessner, C. Qiu, N. Yu, J. Chen, F.Y. Deng, T. Xu, Y. Cheng, Q. Tian, P. Yu, Y.Z Liu, Y.J. Liu, H. Hakonarson, S.F.A. Grant and H.W. Deng: Copy number variation on chromosome 10q26.3 for obesity identified by a genome-wide study. Journal of Clinical Endocrinology and Metabolism 98: E191-E195, 2013.

S. Deliard, S. Panossian, F.D. Mentch, C.E. Kim, C. Hou, E.C. Frackelton, J.P. Bradfield, J.T. Glessner, H. Zhang, K. Wang, P.M.A. Sleiman, R.M. Chiavacci, R.I. Berkowitz, H. Hakonarson, J. Zhao and S.F.A. Grant: The missense variation landscape of FTO, MC4R and TMEM18 in obese children of African ancestry. Obesity 21: 159-163, 2013.

S. Deliard, J. Zhao, Q. Xia and S.F.A. Grant: Generation of High Quality Chromatin Immunoprecipitation DNA Template for High-throughput Sequencing (ChIP-seq). Journal of Visualized Experiments 74: e50286, 2013.

R. Mechelli, R. Umeton, C. Policano, V. Annibali, G. Coarelli, V.A. Ricigliano, D. Vittori, A. Fornasiero, M.C. Buscarinu, International Multiple Sclerosis Genetics Consortium [of which S.F.A. Grant is a member], Wellcome Trust Case Control Consortium 2, S. Romano, M. Salvetti and G. Ristori: A "Candidate-Interactome" Aggregate Analysis of Genome-Wide Association Data in Multiple Sclerosis. PLoS One 8: e63300, 2013.

M.C.Y. Ng, R. Saxena, J. Li, N.D. Palmer, L. Dimitrov, J. Xu, L.J. Rasmussen-Torvik, J.M. Zmuda, D.S. Siscovick, S.R. Patel, E.D. Crook, M. Sims, Y.D. I. Chen, A.G. Bertoni, M. Li, S.F.A. Grant, J. Dupuis, J.B. Meigs, B.M. Psaty, J.S. Pankow, C.D. Langefeld, B.I. Freedman, J.I. Rotter, J.G. Wilson and D.W. Bowden: Transferability and Fine Mapping of Type 2 Diabetes Loci in African Americans: The Candidate Gene Association Resource Plus Study. Diabetes 62: 965-976, 2013.

M. Horikoshi*, H. Yaghootkar*, D.O. Mook-Kanamori*, U. Sovio, H.R. Taal, B.J. Hennig, J.P Bradfield, B. St Pourcain, D.M. Evans, P. Charoen, M. Kaakinen, D.L. Cousminer, T. Lehtimäki, E. Kreiner-Møller, N.M. Warrington, M. Bustamante, B. Feenstra, D.J. Berry, E. Thiering, T. Pfab, S.J. Barton, B.M. Shields, M. Kerkhof, E.M. van Leeuwen, A.J. Fulford, Z. Kutalik, J.H. Zhao, M. den Hoed, A. Mahajan, V. Lindi, L.K. Goh, J.J. Hottenga, Y. Wu, O.T. Raitakari, M.N. Harder, A. Meirhaeghe, I. Ntalla, R.M. Salem, K.A. Jameson, K. Zhou, D.M. Monies, V. Lagou, M. Kirin, J. Heikkinen, L.S. Adair, F.S. Alkuraya, A. Al-Odaib, P. Amouyel, E.A. Andersson, A.J. Bennett, A.I.F. Blakemore, J.L. Buxton, J. Dallongeville, S. Das, E.J.C. de Geus, X. Estivill, C. Flexeder, P. Froguel, F. Geller, K.M. Godfrey, F. Gottrand, C.J. Groves, T. Hansen, J.N. Hirschhorn, A. Hofman, M.V. Hollegaard, D.M. Hougaard, E. Hyppönen, H.M. Inskip, A. Isaacs, T. Jørgensen, C. Kanaka-Gantenbein, J.P. Kemp, W. Kiess, T.O. Kilpeläinen, N. Klopp, B.A. Knight, C.W. Kuzawa, G. McMahon, J.P. Newnham, H. Niinikoski, B.A. Oostra, L. Pedersen, D.S. Postma, S.M. Ring, F. Rivadeneira, N.R. Robertson, S. Sebert, O. Simell, T. Slowinski, C.M.T. Tiesler, A. Tönjes, A. Vaag, J.S. Viikari, J.M. Vink, N.H. Vissing, N.J. Wareham, G. Willemsen, D.R. Witte, H. Zhang, J. Zhao, The Meta-Analyses of Glucose- and Insulin-related traits Consortium (MAGIC), J.F. Wilson, M. Stumvoll, A.M. Prentice, B.F. Meyer, E.R. Pearson, C.A.G. Boreham, C. Cooper, M.W. Gillman, G.V. Dedoussis, L.A. Moreno, O. Pedersen, M. Saarinen, K.L. Mohlke, D.I. Boomsma, S.M. Saw, T.A. Lakka, A. Körner, R.J.F. Loos, K.K. Ong, P. Vollenweider, C.M. van Duijn, G.H. Koppelman, A.T. Hattersley, J.W. Holloway, B. Hocher, J. Heinrich, C. Power, M. Melbye, M. Guxens, C.E. Pennell, K. Bønnelykke, H. Bisgaard, J.G. Eriksson, E. Widén, H. Hakonarson, A.G. Uitterlinden, A. Pouta, D.A. Lawlor, G. Davey Smith, T.M. Frayling, M.I. McCarthy*, S.F.A. Grant*, V.W.V. Jaddoe*, M.R. Jarvelin*, N.J. Timpson*, I. Prokopenko* and R.M. Freathy* for the Early Growth Genetics (EGG) Consortium: New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nature Genetics 45: 76-82, 2013 Notes: *equal contribution.

K.L. Monda*, G.K. Chen*, K.C. Taylor*, C. Palmer*, T.L. Edwards*, L.A. Lange, M.C.Y. Ng, A.A. Adeyemo, M.A. Allison, L.F. Bielak, G. Chen, M. Graff, M.R. Irvin, S.K. Rhie, G. Li, Y. Liu, Y. Liu, Y. Lu, M.A. Nalls, Y.V. Sun, M.K. Wojczynski, L.R. Yanek, M.C. Aldrich, A. Ademola, C.I. Amos, E.V. Bandera, C.H. Bock, A. Britton, U. Broeckel, Q. Cai, N.E. Caporaso, C.S. Carlson, J. Carpten, G. Casey, W.M. Chen, F. Chen, Y.D.I. Chen, C.W.K. Chiang, G.A. Coetzee, E. Demerath, S.L. Deming-Halverson, R.W. Driver, P. Dubbert, M.F. Feitosa, Y. Feng, B.I. Freedman, E.M. Gillanders, O. Gottesman, X. Guo, T. Haritunians, T. Harris, C.C. Harris, A.J.M. Hennis, D.G. Hernandez, L.H. McNeill, T.D. Howard, B.V. Howard, V.J. Howard, K.C. Johnson, S.J. Kang, B.J. Keating, S. Kolb, L.H. Kuller, A. Kutlar, C.D. Langefeld, G. Lettre, K. Lohmurtn, V. Lotay, H. Lyon, J.E. Manson, W. Maixner, Y.A. Meng, K.R. Monroe, I. Morhason-Bello, A.B. Murphy, J.C. Mychaleckyj, R. Nadukuru, K.L. Nathanson, U. Nayak, A. N'Diaye, B. Nemesure, S.Y. Wu, M.C. Leske, C. Neslund-Dudas, M. Neuhouser, S. Nyante, H. Ochs-Balcom, A.Ogunniyi, T.O. Ogundiran, O. Ojengbede, O.I. Olopade, J.R. Palmer, E.A. Ruiz-Narvaez, N.D. Palmer, M.F. Press, E. Rampersaud, L.J. Rasmussen-Torvik, J.L. Rodriguez-Gil, B. Salako, E.E. Schadt, A.G. Schwartz, D.A. Shriner, D. Siscovick, S.B. Smith, S. Wassertheil-Smoller, E.K. Speliotes, M.R. Spitz, L. Sucheston, H. Taylor, B.O. Tayo, M.A. Tucker, D.J. Van Den Berg, D.R. Velez Edwards, Z. Wang, J.K Wiencke, T.W. Winkler, J.S. Witte, M. Wrensch, X. Wu, J.J. Yang, A.M. Levin, T.R. Young, N.A. Zakai, M. Cushman, K.A. Zanetti, J.H. Zhao, W. Zhao, Y. Zheng, J. Zhou, R.G. Ziegler, J.M. Zmuda, J.K. Fernandes, G.S. Gilkeson, D.L. Kamen, K.J. Hunt, I.J. Spruill, C.B. Ambrosone, S. Ambs, D.K. Arnett, L. Atwood, D.M. Becker, S.I. Berndt, L. Bernstein, W.J. Blot, I.B. Borecki, E.P. Bottinger, D.W. Bowden, G. Burke, S.J. Chanock, R.S. Cooper, J. Ding, D. Duggan, M.K. Evans, C. Fox, W.T. Garvey, J.P. Bradfield, H. Hakonarson, S.F.A. Grant, A. Hsing, L. Chu, J.J. Hu, D. Huo, S.A. Ingles, E.M. John, J.M. Jordan, E.K. Kabagambe, S.L.R. Kardia, R.A. Kittles, P.J. Goodman, E.A. Klein, L.N. Kolonel, L. Le Marchand, S. Liu, B. McKnight, R.C. Millikan, T.H. Mosley, B. Padhukasahasram, L.K. Williams, S.R. Patel, U. Peters, C.A. Pettaway, P.A. Peyser, B.M. Psaty, S. Redline, C.N. Rotimi, B.A. Rybicki, M.M. Sale, P.J. Schreiner, L.B. Signorello, A.B. Singleton, J.L. Stanford, S.S. Strom, M.J. Thun, M. Vitolins, W. Zheng, J.H. Moore, S.M. Williams, S. Ketkar, X. Zhu, A.B. Zonderman, NABEC Consortium, UKBEC Consortium, BioBank Japan Project, AGEN Consortium, C. Kooperberg, G.J. Papanicolaou, B.E. Henderson, A.P. Reiner, J.N. Hirschhorn, R.J.F. Loos, K.E. North* and C.A. Haiman*: A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nature Genetics 45: 690-696, 2013.

J.T. Glessner, A.V. Smith, S. Panossian, C.E. Kim, N. Takahashi, K.A. Thomas, F. Wang, K. Seidler, T.B. Harris, L.J. Launer, B. Keating, J. Connolly, P.M.A. Sleiman, J.D. Buxbaum, S.F.A. Grant, V. Gudnason and H. Hakonarson: Copy number variations in alternative splicing gene networks impact lifespan. PLoS ONE 8: e53846, 2013.

J.A. Mitchell, H. Hakonarson, T.R. Rebbeck and S.F.A. Grant: Obesity-susceptibility loci and the tails of the pediatric BMI distribution. Obesity 21: 1256-1260, 2013.

J. Li, J.T. Glessner, H. Zhang, C. Hou, Z. Wei, J.P. Bradfield, F.D. Mentch, Y. Guo, C. Kim, Q. Xia, R.M. Chiavacci, K.A. Thomas, H. Qiu, S.F.A. Grant, S.L. Furth, H. Hakonarson and P.M.A. Sleiman: GWAS of Blood Cell Traits Identifies Novel Associated Loci and Epistatic Interactions in Caucasian and African American Children. Human Molecular Genetics 22: 1457-64, 2013.

I. Gans, E.J. Sarkissian, S.F.A. Grant and T.J. Ganley: Identical Osteochondritis Dissecans Lesions of the Knee in Sets of Monozygotic Twins. Orthopedics 36: e1559-e1562, 2013.

E.A. Tsai*, M.A. Berman*, L.K. Conlin*, H.L. Rehm, M.A. Deardorff, M. Kaur, L. Francey, D.M. Clark, J.T. Glessner, S.T. Jensen, S.F.A. Grant, P.J. Gruber, H. Hakonarson, N.B. Spinner and I.D. Krantz: PECONPI: A Novel Software for Uncovering Pathogenic Copy Number Variations in Non-Syndromic Sensorineural Hearing Loss and Other Genetically Heterogeneous Disorders American Journal of Medical Genetics 161: 2134-47, 2013 Notes: *equal contribution.

D.L. Cousminer, D.J. Berry, N.J. Timpson, W. Ang, E. Thiering, E. Byrne, H.R. Taal, V. Huikari, J.P. Bradfield, M. Kerkhof, M.M. Groen-Blokhuis, E. Kreiner-Møller, M. Marinelli, C. Holst, J.T. Leinonen, J.R.B. Perry, I. Surakka, O. Pietiläinen, J. Kettunen, V. Anttila, M. Kaakinen, U. Sovio, A. Pouta, S. Das, V. Lagou, C. Power, I. Prokopenko, D.M. Evans, J.P. Kemp, B. St Pourcain, S. Ring, A. Palotie, E. Kajantie, C. Osmond, T. Lehtimäki, J.S. Viikari, M. Kähönen, N.M. Warrington, S.J. Lye, L.J. Palmer, C.M.T. Tiesler, C. Flexeder, G.W. Montgomery, S.E. Medland, A. Hofman, H. Hakonarson, M. Guxens, M. Bartels, V. Salomaa, The ReproGen Consortium, J. Murabito, J. Kaprio, T.I.A. Sørensen, F. Ballester, H. Bisgaard, D.I. Boomsma, G.H. Koppelman, S.F.A. Grant, V.W.V. Jaddoe, N.G. Martin, J. Heinrich, C.E. Pennell, O. Raitakari, J.G. Eriksson, G. Davey Smith, E. Hyppönen, M.R. Järvelin, M.I. McCarthy, S. Ripatti and E. Widén for the Early Growth Genetics (EGG) Consortium: Genome-wide Association and Longitudinal Analyses Reveal Genetic Loci Linking Pubertal Height Growth, Pubertal Timing, and Childhood Adiposity. Human Molecular Genetics 22: 2735-2747, 2013.

C.T. Liu*, K.L. Monda*, K.C. Taylor*, L. Lange, E.W. Demerath, W. Palmas, M.K. Wojczynski, J.C. Ellis, M.Z. Vitolins, S. Liu, G.J. Papanicolaou, M.R. Irvin, L. Xue, P.J. Griffin, M.A. Nalls, A. Adeyemo, J. Liu, G. Li, E.A. Ruiz-Narvaez, W.M. Chen, F. Chen, B.E. Henderson, R.C. Millikan, C.B. Ambrosone, S.S. Strom, X. Guo, J.S. Andrews, Y.V. Sun, T.H. Mosley, L.R. Yanek, D. Shriner, T. Haritunians, J.I. Rotter, E.K. Speliotes, M. Smith, L. Rosenberg, J. Mychaleckyj, U. Nayak, I. Spruill, W.T. Garvey, C. Pettaway, S. Nyante, E.V. Bandera, A.F. Britton, A.B. Zonderman, L.J. Rasmussen-Torvik, Y.D.I. Chen, J. Ding, K. Lohman, S.B. Kritchevsky, W. Zhao, P.A. Peyser, S.L.R. Kardia, E. Kabagambe, U. Broeckel, G. Chen, J. Zhou, S. Wassertheil-Smoller, M.L. Neuhouser, E. Rampersaud, B. Psaty, C. Kooperberg, J.E. Manson, L.H. Kuller, H.M. Ochs-Balcom, K.C. Johnson, L. Sucheston, J.M. Ordovas, J.R. Palmer, C.A. Haiman, B. McKnight, B.V. Howard, D.M. Becker, L.F. Bielak, Y. Liu, M.A. Allison, S.F.A. Grant, G.L. Burke, S.R. Patel, P.J. Schreiner, I.B. Borecki, M.K. Evans, H. Taylor, M.M. Sale, V. Howard, C.S. Carlson, C.N. Rotimi, M. Cushman, T.B. Harris, A.P. Reiner, L.A. Cupples, K.E. North* and C.S. Fox*: Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci. PLoS Genetics 9: e1003681, 2013 Notes: *equal contribution.

C.J. Cardinale, Z. Wei, S. Panossian, F. Wang, C.E. Kim, F.D. Mentch, R.M. Chiavacci, K.E. Kachelries, R. Pandey, S.F.A. Grant, R.N. Baldassano and H. Hakonarson: Targeted Resequencing Identifies Defective Variants of Decoy Receptor 3 in Pediatric-Onset Inflammatory Bowel Disease. Genes and Immunity 14: 447-52, 2013.

2012

W.L. Haskell, R.P. Troiano, J.A. Hammond, M.J. Phillips, L.C. Strader, D.X. Marquez, S.F.A. Grant and E. Ramos: Physical Activity and Physical Fitness: Standardizing Assessment with the PhenX Toolkit. American Journal of Preventive Medicine 42: 486-492, 2012.

S.F.A. Grant, J.T. Glessner, J.P. Bradfield, J. Zhao, J.E. Tirone, R.I. Berkowitz, H. Hakonarson and N. Sondheimer: Lack of relationship between mitochondrial heteroplasmy or variation and childhood obesity. International Journal of Obesity 36: 80-3, 2012.

R. Saxena*, C.C. Elbers*, Y. Guo, I. Peter, T.R. Gaunt, J.L. Mega, M.B. Lanktree, A. Tare, B.A. Castillo, Y.R. Li, T. Johnson, M. Bruinenberg, D. Gilbert-Diamond, R. Rajagopalan, B.F. Voight, A. Balasubramanyam, J. Barnard, F. Bauer, J. Baumert, T. Bhangale, B.O. Böhm, P.S. Braund, P.R. Burton, H.R. Chandrupatla, R. Clarke, R.M. Cooper-DeHoff, E.D. Crook, G. Davey-Smith, I.N. Day, A. de Boer, M.C.H. de Groot, F. Drenos, J. Ferguson, C.S. Fox, C.E. Furlong, Q. Gibson, C. Gieger, L.A. Gilhuijs-Pederson, J.T. Glessner, A. Goel, Y. Gong, S.F.A. Grant, D.E. Grobbee, C. Hastie, S.E. Humphries, C.E. Kim, M. Kivimaki, M. Kleber, C. Meisinger, M. Kumari, T.Y. Langaee, D.A. Lawlor, M. Li, M.T. Lobmeyer, A.H. Maitland-van der Zee, M.F.L. Meijs, C.M. Molony, D.A. Morrow, G. Murugesan, S.K. Musani, C.P. Nelson, S.J. Newhouse, J.R. O'Connell, S. Padmanabhan, J. Palmen, S.R. Patel, C.J. Pepine, M. Pettinger, T.S. Price, S. Rafelt, J. Ranchalis, A. Rasheed, E. Rosenthal, I. Ruczinski, S. Shah, H. Shen, G. Silbernagel, E.N. Smith, A.W.M. Spijkerman, A. Stanton, M.W. Steffes, B. Thorand, M. Trip, P. van der Harst, D.L. van der A, E.P.A. van Iperen, J. van Setten, J.V. van Vliet-Ostaptchouk, N. Verweij, B.H.R. Wolffenbuttel, T. Young, M.H. Zafarmand, J.M. Zmuda, the Look AHEAD Research Group, DIAGRAM consortium, M. Boehnke, D. Altshuler, M. McCarthy, W.H.L. Kao, J.S. Pankow, T.P. Cappola, M. Caulfield, A. Dominiczak, D.C. Shields, D. Bhatt, L. Zhang, S.P. Curtis, J. Danesh, J.P. Casas, Y.T. van der Schouw, N.C. Onland-Moret, P.A. Doevendans, G.W. Dorn, M. Farrall, G.A. FitzGerald, A. Hamsten, R. Hegele, A.D. Hingorani, M.H. Hofker, G.S. Huggins, T. Illig, G.P. Jarvik, J.A. Johnson, O.H. Klungel, W.C. Knowler, W. Koenig, W. März, J.B. Meigs, O. Melander, P.B. Munroe, B.D. Mitchell, S.J. Bielinski, D.J. Rader, M.P. Reilly, S.S. Rich, J.I. Rotter, D. Saleheen, N.J. Samani, E.E. Schadt, A.R. Shuldiner, R. Silverstein, K. Kottke-Marchant, P.J. Talmud, H. Watkins, F. Asselbergs, P.I.W. de Bakker, J. McCaffery, C. Wijmenga, M.S. Sabatine, J.G. Wilson, A. Reiner, D.W. Bowden, H. Hakonarson, D.S. Siscovick and B.J. Keating: Large-Scale Gene-Centric Meta-Analysis across 39 studies Identifies Type 2 Diabetes Loci. American Journal of Human Genetics 90: 410-425, 2012.

M.A. Ikram*, M. Fornage*, A.V. Smith*, S. Seshadri*, R. Schmidt*, S. Debette, H.A. Vrooman, S. Sigurdsson, S. Ropele, H.R. Taal, D.O. Mook-Kanamori, L.H. Coker, W.T. Longstreth Jr, W.J. Niessen, A.L. DeStefano, A. Beiser, A.P. Zijdenbos, M. Struchalin, C.R. Jack Jr, F. Rivadeneira, A.G. Uitterlinden, D.S. Knopman, A.L. Hartikainen, C.E. Pennell, E. Thiering, E.A.P. Steegers, H. Hakonarson, J. Heinrich, L.J. Palmer, M.R. Jarvelin, M.I. McCarthy, S.F.A. Grant, B. St Pourcain, N.J. Timpson, G. Davey Smith, U. Sovio, the Early Growth Genetics (EGG) Consortium, M.A. Nalls, R. Au, A. Hofman, H. Gudnason, A. van der Lugt, T.B. Harris, W.M. Meeks, M.W. Vernooij, M.A. van Buchem, D. Catellier, V.W.V. Jaddoe, V. Gudnason, B.G. Windham, P.A. Wolf, C.M. van Duijn, T.H. Mosley Jr*, H. Schmidt*, L.J. Launer*, M.M.B. Breteler* and C. DeCarli* for the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Common variants at 6q22 and 17q21 are associated with intracranial volume. Nature Genetics 44: 539-544, 2012 Notes: *equal contribution; COVER STORY.

K. Wang, H. Zhang, F.D. Mentch, J.P. Bradfield, J.T. Glessner, H. Qiu, Y. Guo, C. Hou, E.C. Frackelton, K. Thomas, A. Bender, A. Albano, G. Otieno, K. Seidler, A. Moy, C.E. Kim, B. Keating, R.M. Chiavacci, R. Grundmeier, P.A. Sleiman, S.F.A. Grant and H. Hakonarson: Examination of genetic variants influencing lipid traits in pediatric populations. Journal of Pediatric Genetics 2: 85-99, 2012.

J.P. Bradfield*, H.R. Taal*, N.J Timpson, A. Scherag, C. Lecoeur, N.M. Warrington, E. Hypponen, C. Holst, B. Valcarcel, E. Thiering, R.M. Salem, F.R. Schumacher, D.L. Cousminer, P.M.A. Sleiman, J. Zhao, R.I. Berkowitz, K.S. Vimaleswaran, I. Jarick, C.E. Pennell, D.M. Evans, B. St Pourcain, D.J. Berry, D.O. Mook-Kanamori, A. Hofman, F. Rivadeneira, A.G. Uitterlinden, C.M. van Duijn, R.J.P. van der Valk, J.C. de Jongste, D.S. Postma, D.I. Boomsma, W.J. Gauderman, M.T. Hassanein, C.M. Lindgren, R. Mägi, C.A.G. Boreham, C.E. Neville, L.A. Moreno, P. Elliott, A. Pouta, A.L. Hartikainen, M. Li, O. Raitakari, T. Lehtimäki, J.G Eriksson, A. Palotie, J. Dallongeville, S. Das, P. Deloukas, G. McMahon, S.M. Ring, J.P. Kemp, J.L. Buxton, A.I.F. Blakemore, M. Bustamante, M. Guxens, J.N. Hirschhorn, M.W. Gillman, E. Kreiner-Møller, H. Bisgaard, F.D. Gilliland, J. Heinrich, E. Wheeler, I. Barroso, S. O'Rahilly, A. Meirhaeghe, T.I.A. Sørensen, C. Power, L.J. Palmer, A. Hinney, E. Widen, I.S. Farooqi, M.I. McCarthy, P. Froguel, D. Meyre, J. Hebebrand, M.R. Jarvelin, V.W.V. Jaddoe, G. Davey Smith, H. Hakonarson and S.F.A. Grant for the Early Growth Genetics (EGG) Consortium: A genome-wide association meta-analysis identifies new childhood obesity loci. Nature Genetics 44: 526-531, 2012 Notes: *equal contribution.

J. Zhao*, S. Deliard*, A.R. Aziz and S.F.A. Grant: Expression analyses of the genes harbored by the type 2 diabetes and pediatric BMI associated locus on 10q23. BMC Medical Genetics 13: 89, 2012 Notes: *equal contribution.

J. Tyrrell, V. Huikari, J.T. Christie, A. Cavadino, R. Bakker, M.J.A. Brion, F. Geller, L. Paternoster, Ronny Myhre, C. Potter, P.C.D. Johnson, S. Ebrahim, B. Feenstra, A.L. Hartikainen, A.T. Hattersley, A. Hofman, M. Kaakinen, L.P. Lowe, P. Magnus, A. McConnachie, M. Melbye, J.W.Y. Ng, E.A. Nohr, C. Power, S.M. Ring, S.P. Sebert, V. Sengpiel, H.R. Taal, G.C.M. Watt, N. Sattar, C.L. Relton, B. Jacobsson, T.M. Frayling, T.I.A. Sørensen, J.C. Murray, D.A. Lawlor, C.E. Pennell, V.W.V. Jaddoe, E. Hypponen, W.L. Lowe, M.R. Jarvelin, G. Davey Smith and R.M. Freathy, for the Early Growth Genetics (EGG) Consortium [of which S.F.A. Grant is a member]: Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight. Human Molecular Genetics 21: 5344-58, 2012.

J. Elia*, J.T. Glessner*, K. Wang, N. Takahashi, C.J. Shtir, D. Hadley, P.M.A. Sleiman, H. Zhang, C.E. Kim, R. Robison, G.J. Lyon, J.H. Flory, J.P. Bradfield, M. Imielinski, C. Hou, E.C. Frackelton, R.M. Chiavacci, T. Sakurai, C. Rabin, F.A. Middleton, K.A. Thomas, M. Garris, F. Mentch, C.M. Freitag, H.C. Steinhausen, A.A. Todorov, A. Reif, A. Rothenberger, B. Franke, E.O. Mick, H. Roeyers, J. Buitelaar, K.P. Lesch, T. Banaschewski, R.P. Ebstein, F. Mulas, R.D. Oades, J. Sergeant, E. Sonuga-Barke, T.J. Renner, M. Romanos, J. Romanos, A. Warnke, S. Walitza, J. Meyer, H. Pálmason, C. Seitz, S.K. Loo, S.L. Smalley, J. Biederman, L. Kent, P. Asherson, R.J.L. Anney, J.W. Gaynor, P. Shaw, M. Devoto, P.S. White, S.F.A. Grant, J.D. Buxbaum, J.L Rapoport, N.M. Williams, S.F. Nelson, S.V. Faraone and H. Hakonarson: Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder. Nature Genetics 44: 78-84, 2012 Notes: *equal contribution.

H.R. Taal*, B. St Pourcain*, E. Thiering*, S. Das*, D.O. Mook-Kanamori*, N.M. Warrington, M. Kaakinen, E. Kreiner-Møller, J.P. Bradfield, R.M. Freathy, F. Geller, M. Guxens, D.L. Cousminer, M. Kerkhof, N.J. Timpson, M.A. Ikram, L.J. Beilin, K. Bønnelykke, J.L. Buxton, P. Charoen, B.L.K. Chawes, J. Eriksson, D.M. Evans, A. Hofman, J.P. Kemp, C.E. Kim, N. Klopp, J. Lahti, S.J. Lye, G. McMahon, F.D. Mentch, M. Müller-Nurasyid, P.F. O'Reilly, I. Prokopenko, F. Rivadeneira, E.A.P. Steegers, J. Sunyer, C. Tiesler, H. Yaghootkar, The Cohorts for Heart and Aging Research in Genetic Epidemiology (CHARGE) Consortium, M.M.B. Breteler, S. Debette, M. Fornage, V. Gudnason, L.J. Launer, A. van der Lugt, T.H. Mosley Jr, S. Seshadri, A.V. Smith, M.W. Vernooij, The Early Genetics & Lifecourse Epidemiology (EAGLE) Consortium, A.I. F. Blakemore, R.M. Chiavacci, B. Feenstra, J. Fernandez-Banet, S.F.A. Grant, A.L. Hartikainen, A.J. van der Heijden, C. Iñiguez, M. Lathrop, W.L. McArdle, A. Mølgaard, J.P. Newnham, L.J. Palmer, A. Palotie, A. Pouta, S.M. Ring, U. Sovio, M. Standl, A.G. Uitterlinden, H.E. Wichmann, N.H. Vissing, C. DeCarli, C.M. van Duijn, M.I. McCarthy, G.H. Koppelman, X. Estivill, A.T. Hattersley, M. Melbye, H. Bisgaard, C.E. Pennell, E. Widen, H. Hakonarson, G. Davey Smith*, J. Heinrich*, M.R. Jarvelin* and V.W.V. Jaddoe* for the Early Growth Genetics (EGG) Consortium: Common variants at 12q15 and 12q24 are associated with infant head circumference. Nature Genetics 44: 532-538, 2012 Notes: *equal contribution.

G.A. Walford, T. Green, B. Neale, T. Isakova, J.I. Rotter, S.F.A. Grant, C.S. Fox, J.S. Pankow, J.G. Wilson, J.B. Meigs, D.S. Siscovick, D.W. Bowden, M.J. Daly and J.C. Florez: Common genetic variants differentially influence the transition from clinically defined states of fasting glucose metabolism. Diabetologia 55: 331-9, 2012.

C.T. Liu, M.C.Y. Ng, D. Rybin, A. Adeyemo, S.J. Bielinski, E. Boerwinkle, I. Borecki, B. Cade, Y.D.I. Chen, L. Djousse, M. Fornage, M.O. Goodarzi, S.F.A. Grant, X. Guo, T. Harris, E. Kabagambe, J.R. Kizer, Y. Liu, K.L. Lunetta, K. Mukamal, J.A. Nettleton, J.S. Pankow, S.R. Patel, E. Ramos, L. Rasmussen-Torvik, S.S. Rich, C.N. Rotimi, D. Sarpong, D. Shriner, M. Sims, J.M. Zmuda, S. Redline, W.H. Kao, D. Siscovick, J.C. Florez, J.I. Rotter, J. Dupuis, J.G. Wilson, D.W. Bowden and J.B. Meigs: Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource. Diabetologia 55: 2970-84, 2012.

2011

T.O. Kilpelainen, M. den Hoed, K.K. Ong, A. Grøntved, S. Brage, Early Growth Genetics Consortium [of which S.F.A. Grant is a member], K. Jameson, C. Cooper, K.T. Khaw, U. Ekelund, N.J. Wareham and R.J.F. Loos: Obesity-susceptibility loci have a limited influence on birth weight: a meta-analysis of up to 28,219 individuals. American Journal of Clinical Nutrition 93: 851-60, 2011.

S. Sharma, X. Gao, D. Londono, S.E. Devroy, K.N. Mauldin, J.T. Frankel, J.M. Brandon, D. Zhang, Q.Z. Li, M.B. Dobbs, C.A. Gurnett, S.F.A. Grant, H. Hakonarson, J.P. Dormans, J.A. Herring, D. Gordon and C.A. Wise: Genome-wide association studies of adolescent idiopathic scoliosis suggest candidate susceptibility genes. Human Molecular Genetics 20: 1456-66, 2011.

S. Sawcer*, G. Hellenthal*, M. Pirinen*, C.C.A. Spencer*, N.A. Patsopoulos, L. Moutsianas, A. Dilthey, Z. Su, C. Freeman, S.E. Hunt, S. Edkins, E. Gray, D.R. Booth, S.C. Potter, A. Goris, G. Band, A.B. Oturai, A. Strange, J. Saarela, C. Bellenguez, B. Fontaine, M. Gillman, B. Hemmer, R. Gwilliam, F. Zipp, A. Jayakumar, R. Martin, S. Leslie, S. Hawkins, E. Giannoulatou, S. D'alfonso, H. Blackburn, ..., P..W. de Bakker, M. Debouverie, M.B. D'hooghe, K. Dixon, R. Dobosi, B. Dubois, D. Ellinghaus, I. Elovaara, F. Esposito, C. Fontenille, S. Foote, A. Franke, D. Galimberti, A. Ghezzi, J. Glessner, R. Gomez, O. Gout, C. Graham, S.F.A. Grant, F.R. Guerini, H. Hakonarson, P. Hall, A. Hamsten, H.P. Hartung, R.N. Heard, S. Heath, J. Hobart, M. Hoshi, C. Infante-Duarte, G. Ingram, W. Ingram, T. Islam, M. Jagodic, M. Kabesch, A.G. Kermode, T.J. Kilpatrick, C. Kim, N. Klopp, K. Koivisto, M. Larsson, M. Lathrop, ...., K. Wang, C.G. Mathew, J. Wason, C.N.A. Palmer, H.E. Wichmann, R. Plomin, E. Willoughby, A. Rautanen, J. Winkelmann, M. Wittig, R.C. Trembath, J. Yaouanq, A.C. Viswanathan, H. Zhang, N.W. Wood, R. Zuvich, P. Deloukas, C. Langford, A. Duncanson, J.R. Oksenberg, M.A. Pericak-Vance, J.L. Haines, T. Olsson, J. Hillert, A.J. Ivinson, P.L. De Jager, L. Peltonen, G.J. Stewart, D.A. Hafler, S.L. Hauser, G. McVean, P. Donnelly* and A. Compston*: Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 476: 214-219, 2011 Notes: *equal contribution.

M.B. Lanktree*, Y. Guo*, M. Murtaza, J.T. Glessner, S.D. Bailey, N.C. Onland-Moret, G. Lettre, H. Ongen, R. Rajagopalan, T. Johnson, H. Shen, C.P. Nelson, N. Klopp, J. Baumert, S. Padmanabhan, N. Pankratz, J.S. Pankow, S. Shah, K. Taylor, J. Barnard, B.J. Peters, ..., N.J. Timpson, S. Tischfield, M. Tobin, M. Tomaszweski, W.M. M. Verschuren, C. Wallace, B. Winkelmann, H. Zhang, D. Zheng, L. Zhang, J.M. Zmuda, R. Clarke, A.J. Balmforth, J. Danesh, I.N. Day, N.J. Schork, P.I.W. de Bakker, C. Delles, D. Duggan, A.D. Hingorani, J.N. Hirschhorn, M.H. Hofker, S.E. Humphries, M. Kivimaki, D.A. Lawlor, K. Kottke-Marchant, J.L. Mega, B.D. Mitchell, D.A. Morrow, J. Palmen, S. Redline, D.C. Shields, A.R. Shuldiner, P.M. Sleiman, G.D. Smith, M. Farrall, Y. Jamshidi, D.C. Christiani, J.P. Casas , A.S. Hall, P.A. Doevendans, J.D. Christie, G.S. Berenson, S.S. Murray, T. Illig, G.W. Dorn, T.P. Cappola, E. Boerwinkle, P. Sever, D.J. Rader, M.P. Reilly, M. Caulfield, P.J. Talmud, E. Topol, J.C. Engert, K. Wang, A. Dominiczak, A. Hamsten, S.P. Curtis, R.L. Silverstein, L.A. Lange, M.S. Sabatine, M. Trip, D. Saleheen, J.F. Peden, K.J. Cruickshanks, W. März, J.R. O'Connell, O.H. Klungel, C. Wijmenga, A.H. Maitland-van der Zee, E.E. Schadt, J.A. Johnson , G.P. Jarvik, G.J. Papanicolaou, S.F.A. Grant, P.B. Munroe, K.E. North, N.J. Samani, W. Koenig, T.R. Gaunt, S.S. Anand, Y.T. van der Schouw, N. Soranzo, G.A. FitzGerald, A. Reiner, R.A. Hegele, H. Hakonarson and B.J. Keating: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. American Journal of Human Genetics 88: 6-18, 2011 Notes: *equal contribution.

K.S. Lo, J.G. Wilson, L.A. Lange, A.R. Folsom, G. Galarneau, S.K. Ganesh, S.F.A. Grant, B.J. Keating, S.A. McCarroll, E.R. Mohler III, C.J. O'Donnell, W. Palmas, W. Tang, R.P. Tracy, A.P. Reiner and G. Lettre: Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans. Human Genetics 129: 307-17, 2011.

K. Wang, A.C. Edmondson, M. Li, A.N. Qasim, J.M. Devaney, M.S. Burnett, D.M. Waterworth, V. Mooser, S.F.A. Grant, S.E. Epstein, M.P. Reilly, H. Hakonarson and D.J. Rader: Pathway-wide association study implicates multiple sterol transport and metabolism genes in HDL cholesterol regulation Frontiers in Genetics 2: 41, 2011.

K. Wang*, W.D. Li*, C. Zhang, A. Wang, J.T. Glessner, S.F.A. Grant, H. Zhao, H. Hakonarson and R.A. Price: A genome-wide association study on obesity and obesity-related traits. PLoS ONE 6: e18939, 2011 Notes: *equal contribution.

K. Wang*, S.J. Diskin*, H. Zhang*, E.F. Attiyeh, C. Winter, C. Hou, R.W. Schnepp, M. Diamond, K. Bosse, P.A. Mayes, J. Glessner, C. Kim, E. Frackelton, M. Garris, Q. Wang, W. Glaberson, R. Chiavacci, L. Nguyen, J. Jagannathan, N. Saeki, H. Sasaki, S.F.A. Grant, A. Iolascon, Y.P. Mosse, K.A. Cole, H. Li, M. Devoto, P.W. McGrady, W.B. London, M. Capasso, N. Rahman, H. Hakonarson and J.M. Maris: Integrative genomics identifies LMO1 as a neuroblastoma oncogene. Nature 469: 216-220, 2011 Notes: *equal contribution.

J.P. Bradfield, H.Q. Qu, K. Wang, H. Zhang, P.M. Sleiman, C.E. Kim, F.D. Mentch, H. Qiu, J.T. Glessner, K.A. Thomas, E.C. Frackelton, R.M. Chiavacci, M. Imielinski, D.S. Monos, R. Pandey, M. Bakay, S.F.A. Grant, C. Polychronakos and H. Hakonarson: A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci PLoS Genetics 7: e1002293, 2011.

J. Zhao, J.P. Bradfield, M. Li, H. Zhang, F.D. Mentch, K. Wang, P.M. Sleiman, C.E. Kim, J.T. Glessner, E.C. Frackelton, R.M. Chiavacci, R.I. Berkowitz, B.S. Zemel, H. Hakonarson and S.F.A. Grant: BMD-associated variation at the Osterix locus is correlated with childhood obesity in females. Obesity 19: 1311-4, 2011.

J. Zhao*, J.P. Bradfield*, H. Zhang, P.M. Sleiman, C.E. Kim, J.T. Glessner, S. Deliard, K.A. Thomas, E.C. Frackelton, M. Li, R.M. Chiavacci, R.I. Berkowitz, H. Hakonarson and S.F.A. Grant: Role of adult BMI-associated loci identified in GWAS meta-analyses in the context of common childhood obesity in European Americans. Obesity 19: 2436-9, 2011 Notes: *equal contribution.

D.O. Mook-Kanamori*, J.A. Marsh*, N.M. Warrington, H.R. Taal, J.P. Newnham, L.J. Beilin, S.J. Lye, L.J. Palmer, A. Hofman, E.A.P. Steegers, C.E. Pennell*, the Early Growth Genetics Consortium [of which S.F.A. Grant is a member] and V.W.V. Jaddoe*: Variants near CCNL1/LEKR1 and in ADCY5 and Fetal Growth Characteristics in Different Trimesters. Journal of Clinical Endocrinology and Metabolism 96: E810-E815, 2011 Notes: *equal contribution.

A.P. Reiner*, G. Lettre*, M.A. Nalls*, S.K. Ganesh*, R. Mathias*, M.A. Austin*, E. Dean*, S. Arepalli, A. Britton, Z. Chen, D. Couper, J.D. Curb, C.B. Eaton, M. Fornage, S.F.A. Grant, T.B. Harris, D. Hernandez, N. Kamatini, B.J. Keating, M. Kubo, A. LaCroix, L.A. Lange, S. Liu, K. Lohman, Y. Meng, E.R. Mohler 3rd, S. Musani, Y. Nakamura, C.J. O'Donnell, Y. Okada, C.D. Palmer, G. Papanicolaou, K. Patel, A.B. Singleton, A. Takahashi, H. Tang, H.A. Taylor Jr, K. Taylor, C. Thomson, L.R. Yanek, L. Yang, E. Ziv, A.B. Zonderman, A.R. Folsom*, M.K. Evans*, Y. Liu*, D.M. Becker*, B.M. Snively* and J.G. Wilson*: Genome-wide association study of white blood cell count in 16,388 African Americans: the Continental Origins and Genetic Epidemiology Network (COGENT). PLoS Genetics 7: e1002108, 2011 Notes: *equal contribution.

2010

R.M Freathy*, D.O. Mook-Kanamori*, U. Sovio*, I. Prokopenko*, N.J. Timpson*, D.J Berry*, N.M Warrington*, E. Widen, J.J. Hottenga, M. Kaakinen, L.A. Lange, J.P. Bradfield, M. Kerkhof, J.A. Marsh, R. Mägi, C.M. Chen, H.N. Lyon, M. Kirin, L.S. Adair, Y.S. Aulchenko, A.J. Bennett, J.B. Borja, N. Bouatia-Naji, P. Charoen, L.J.M. Coin, D.L. Cousminer, E.J.C. de Geus, P. Deloukas, P. Elliott, D.M. Evans, P. Froguel, The Genetic Investigation of ANthropometric Traits (GIANT) Consortium, B. Glaser, C.J. Groves, A.L. Hartikainen, N. Hassanali, J.N. Hirschhorn, A. Hofman, J.M.P. Holly, E. Hyppönen, S. Kanoni, B.A. Knight, J. Laitinen, C.M. Lindgren, The Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC), W.L. McArdle, P.F. O'Reilly, C.E. Pennell, D.S. Postma, A. Pouta, A. Ramasamy, N.W. Rayner, S.M. Ring, F. Rivadeneira, B.M. Shields, D.P. Strachan, I. Surakka, A. Taanila, C. Tiesler, A.G. Uitterlinden, C.M. van Duijn, The Wellcome Trust Case Control Consortium (WTCCC), A.H. Wijga, G. Willemsen, H. Zhang, J. Zhao, J.F. Wilson, E.A.P. Steegers, A.T. Hattersley, J.G. Eriksson, L. Peltonen, K.L. Mohlke, S.F.A. Grant, H. Hakonarson, G.H. Koppelman, G.V. Dedoussis, J. Heinrich, M.W. Gillman, L.J. Palmer, T.M. Frayling, D.I. Boomsma, G. Davey Smith, C. Power, V.W.V. Jaddoe, M.R. Jarvelin and M.I. McCarthy, for the Early Growth Genetics (EGG) Consortium: Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nature Genetics 42: 430-435, 2010 Notes: *equal contribution.

P.M.A. Sleiman, J. Flory, M. Imielinski, J.P. Bradfield, K. Annaiah, S.A.G. Willis-Owen, K. Wang, N.M. Rafaels, S. Michel, K. Bonnelykke, H. Zhang, C.E. Kim, E.C. Frackelton, J.T. Glessner, C. Hou, F.G. Otieno, E. Santa, K. Thomas, R.M. Smith, W.R. Glaberson, M. Garris, R.M. Chiavacci, T.H. Beaty, I. Ruczinski, J. Orange, J. Allen, J.M. Spergel, R. Grundmeier, R.A. Mathias, J.D. Christie, E. von Mutius, W.O.C. Cookson, M. Kabesch, M.F. Moffatt, M.M. Grunstein, K.C. Barnes, M. Devoto, M. Magnusson, H. Li, S.F.A. Grant, H. Bisgaard and H. Hakonarson: A locus on 1q31 harboring DENND1B is associated with asthma susceptibility in both Caucasian and African American children. New England Journal of Medicine 362: 36-44, 2010.

M.E. Rothenberg*, J.M. Spergel*, J.D. Sherrill*, K. Annaiah*, L.J. Martin*, A. Cianferoni, L. Gober, C. Kim, J. Glessner, E. Frackelton, K. Thomas, C. Blanchard, C. Liacouras, R. Verma, S. Aceves, M.H. Collins, T. Brown-Whitehorn, P.E. Putnam, J.P. Franciosi, R.M. Chiavacci, S.F.A. Grant, P. Abonia, P.M.A. Sleiman and H. Hakonarson: Common variants at 5q22 associate with pediatric eosinophilic esophagitis Nature Genetics 42: 289-291, 2010 Notes: *equal contribution.

K. Wang, W.D. Li, J.T. Glessner, S.F.A. Grant, H. Hakonarson and R. A. Price: Large copy number variations are enriched in cases with moderate to extreme obesity. Diabetes 59: 2690-4, 2010.

K. Wang, R. Baldassano, H. Zhang, H. Qi Qu, M. Imielinski, S. Kugathasan, V. Annese, M. Dubinsky, R.K. Russell, J.P. Bradfield, P.M.A. Sleiman, J. Glessner, T. Walters, C. Hou, C. Kim, E.C. Frackelton, M. Garris, J. Doran, P. Lionetti, A. Barabino, J. Van Limbergen, S. Guthery, L. Denson, D. Piccoli, M. Silverberg, C. Stanley, D. Monos, D.C. Wilson, A. Griffiths, S.F.A. Grant, J. Satsangi, C. Polychronakos and H. Hakonarson: Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects. Human Molecular Genetics 19: 2059-2067, 2010.

K. Wang, M. Bucan, S.F.A. Grant, G. Schellenberg and H. Hakonarson: Strategies for Genetic Studies of Complex Diseases. Cell 142: 351-353, 2010.

J.T. Glessner, M.P. Reilly, C.E. Kim, N. Takahashi, A. Albano, C. Hou, J.P. Bradfield, H. Zhang, P.M.A. Sleiman, J.H. Flory, M. Imielinski, E.C. Frackelton, R. Chiavacci, K.A. Thomas, M. Garris, F.G. Otieno, M. Davidson, M. Weiser, A. Reichenberg, K.L. Davis, J.I. Friedman, T.P. Cappola, K.B. Margulies, D.J. Rader, S.F.A. Grant, J.D. Buxbaum, R.E. Gur and H. Hakonarson: Strong synaptic transmission impact by copy number variations in schizophrenia. Proceedings of the National Academy of Sciences 107: 10584-9, 2010.

J.T. Glessner, K. Wang, P.M.A. Sleiman, H. Zhang, C.E. Kim, J.H. Flory, J.P. Bradfield, M. Imielinski, E.C. Frackelton, H. Qiu, F. Mentch, S.F.A. Grant and H. Hakonarson: Duplication of the SLIT3 Locus on 5q35.1 Predisposes to Major Depressive Disorder. PLoS One 5: e15463, 2010.

J.T. Glessner, J.P. Bradfield, K. Wang, N. Takahashi, H. Zhang, P.M. Sleiman, F.D. Mentch, C.E. Kim, C. Hou, K.A. Thomas, M.L. Garris, S. Deliard, E.C. Frackelton, F.G. Otieno, J. Zhao, R.M. Chiavacci, M. Li, J.D. Buxbaum, R.I. Berkowitz, H. Hakonarson* and S.F.A. Grant*: A Genome-wide Study Reveals Copy Number Variants Exclusive to Childhood Obesity Cases American Journal of Human Genetics 87: 661-666, 2010 Notes: *equal contribution.

J. Zhao, J.P. Bradfield, H. Zhang, K. Annaiah, K. Wang, C.E. Kim, J.T. Glessner, E.C. Frackelton, F.G. Otieno, J. Doran, K.A. Thomas, M. Garris, C. Hou, R.M. Chiavacci, M. Li, R.I. Berkowitz, H. Hakonarson and S.F.A. Grant: Examination of all type 2 diabetes GWAS loci reveals HHEX-IDE as a locus influencing pediatric BMI. Diabetes 59: 751-755, 2010.

J. Zhao*, M. Li*, J.P. Bradfield, H. Zhang, F.D. Mentch, K. Wang, P.M. Sleiman, C.E. Kim, J.T. Glessner, C. Hou, B.J. Keating, K.A. Thomas, M.L. Garris, S. Deliard, E.C. Frackelton, F.G. Otieno, R.M. Chiavacci, R.I. Berkowitz, H. Hakonarson and S.F.A. Grant: The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. BMC Medical Genetics 11: 96, 2010 Notes: *equal contribution.

J. Zhao*, J. Schug*, M. Li, K.H. Kaestner and S.F.A. Grant: Disease-associated loci are significantly over-represented among genes bound by TCF7L2 in vivo. Diabetologia 53: 2340-6, 2010 Notes: *equal contribution.

J. Elia*, X. Gai*, H.M. Xie, J.C. Perin, E. Geiger, J.T. Glessner, M. D'arcy, R. deBeradinis, E. Frackelton, C. Kim, F. Lantieri, B.M. Muganga, L. Wang, Toshinobu Takeda, E.F. Rappaport, S.F.A. Grant, W. Berrettini, M. Devoto, T.H. Shaikh, H. Hakonarson and P.S. White: Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes. Molecular Psychiatry 15: 637-46, 2010 Notes: *equal contribution.

H.Q. Qu, J.P. Bradfield, Q. Li, C. Kim, E. Frackelton, S.F.A. Grant, H. Hakonarson and C. Polychronakos: In Silico Replication of the Genome-wide Association Results of the Type 1 Diabetes Genetics Consortium Human Molecular Genetics 19: 2534-8, 2010.

B. St. Pourcain, K. Wang, J.T. Glessner, J. Golding, C. Steer, S.M. Ring, D.H. Skuse, S.F.A. Grant, H. Hakonarson and G. Davey Smith: Association Between a High-Risk Autism Locus on 5p14 and Social Communication Spectrum Phenotypes in the General Population. American Journal of Psychiatry 167: 1364-72, 2010.

A.K. Mondal*, S.K. Das*, G. Baldini, W.S. Chu, N.K. Sharma, O.G. Hackney, J. Zhao, S.F.A. Grant and S.C. Elbein: Genotype and Tissue Specific Effects on Alternative Splicing of the Transcription Factor 7-like 2 Gene in Humans. Journal of Clinical Endocrinology & Metabolism 95: 1450-1457, 2010 Notes: *equal contribution.

2009

Z. Wei*, K. Wang*, H.Q. Qu, H. Zhang, J.P. Bradfield, C. Kim, E. Frackleton, C. Hou, J. T. Glessner, R. Chiavacci, C. Stanley, D. Monos, S.F.A. Grant, C. Polychronakos and H. Hakonarson: From Disease Association to Risk Assessment: An Optimistic View from Genome-Wide Association Studies on Type 1 Diabetes PLoS Genetics 5: e1000678, 2009 Notes: *equal contribution.

T.H. Shaikh*, X. Gai*, J.C. Perin, J.T. Glessner, H. Xie, K. Murphy, R. O'Hara, T. Casalunovo, L.K. Conlin, M. D'arcy, E.C. Frackelton, E.A. Geiger, C. Haldeman-Englert, M. Imielinski, C.E. Kim, L. Medne, K. Annaiah, J.P. Bradfield, E. Dabaghyan, A. Eckert, C.C. Onyiah, S. Ostapenko, F.G. Otieno, E. Santa, J.L. Shaner, R. Skraban, R.M. Smith, J. Elia, E. Goldmuntz, N.B. Spinner, E.H. Zackai, R.M. Chiavacci, R. Grundmeier, E.F. Rappaport, S.F.A. Grant, P.S. White and H. Hakonarson: High-Resolution Mapping and Analysis of Copy Number Variations in the Human Genome: A Data Resource for Clinical and Research Applications. Genome Research 19: 1682-90, 2009 Notes: *equal contribution.

S.J. Diskin, C. Hou, J.T. Glessner, E.F. Attiyeh, M. Laudenslager, K. Bosse, K. Cole, Y.P. Mosse, A. Wood, J.E. Lynch, K. Pecor, M. Diamond, C. Winter, K. Wang, C. Kim, E.A. Geiger, P.W. McGrady, A.I.F. Blakemore, W.B. London, T.H. Shaikh, J. Bradfield, S.F.A. Grant, H. Li, M. Devoto, E.R. Rappaport, H. Hakonarson and J.M. Maris: Copy number variation at 1q21.1 associated with neuroblastoma. Nature 459: 987-991, 2009.

S.F.A. Grant, M. Petri, J.P. Bradfield, C.E. Kim, E. Santa, K. Annaiah, E.C. Frackelton, J.T. Glessner, F.G. Otieno, J.L. Shaner, R.M. Smith, A.W. Eckert, R.M. Chiavacci, M. Imielinski, K.E. Sullivan and H. Hakonarson: Association of the BANK1 R61H variant with systemic lupus erythematosus in Americans of European and African ancestry. Application of Clinical Genetics 2(1-5), 2009.

S.F.A. Grant, K. Wang, H. Zhang, W. Glaberson, K. Annaiah, C.E. Kim, J.P. Bradfield, J.T. Glessner, K.A. Thomas, M. Garris, E.C. Frackelton, F.G. Otieno, R.M. Chiavacci, H.D. Nah, R.E. Kirschner and H. Hakonarson: A genome-wide association study identifies a locus for non-syndromic cleft lip with or without cleft palate on 8q24. Journal of Pediatrics 155: 909-13, 2009.

S.F.A. Grant, J.P. Bradfield, H. Zhang, K. Wang, C.E. Kim, K. Annaiah, E. Santa, J.T. Glessner, K. Thomas, M. Garris, E.C. Frackelton, F.G. Otieno, J.L. Shaner, R.M. Smith, M. Imielinski, R.M. Chiavacci, M. Li, R.I. Berkowitz and H. Hakonarson: Investigation of the locus near MC4R with childhood obesity in Americans of European and African ancestry. Obesity 17: 1461-1465, 2009.

S.F.A. Grant*, H. Qu*, J.P. Bradfield, L. Marchand, C.E. Kim, J.T. Glessner, R. Grabs, S.P. Taback, E.C. Frackelton, A.W. Eckert, K. Annaiah, M.L. Lawson, F.G. Otieno, E. Santa, J.L. Shaner, R.M. Smith, R. Skraban, M. Imielinski, R.M. Chiavacci, R.W. Grundmeier, C.A. Stanley, S.E. Kirsch, D. Waggott, A.D. Paterson, The DCCT/EDIC Research Group, D.S. Monos, C. Polychronakos and H. Hakonarson: Follow up analysis of genome-wide association data identifies novel loci for type 1 diabetes. Diabetes 58: 290-5, 2009 Notes: *equal contribution.

M. Li, K. Wang, S.F.A. Grant, H. Hakonarson and C. Li: ATOM - A Powerful Gene-Based Association Test by Combining Optimally Weighted Markers. Bioinformatics 25(4): 497-503, 2009.

M. Capasso, M. Devoto, C. Hou, Shahab Asgharzadeh, J.T. Glessner, E.F. Attiyeh, Y.P. Mosse, C. Kim, S.J. Diskin, K.A. Cole, K. Bosse, M. Diamond, M. Laudenslager, C. Winter, J.P. Bradfield, R.H. Scott, J. Jagannathan, M. Garris, C. McConville, W.B. London, R.C. Seeger, S.F.A. Grant, H. Li, N. Rahman, E. Rappaport, H. Hakonarson and J.M. Maris: Common variations in BARD1 influence susceptibility to high-risk neuroblastoma. Nature Genetics 41: 718-723, 2009.

M. Bucan*, B.S. Abrahams*, K. Wang*, J.T. Glessner, E.I. Herman, L.I. Sonnenblick, A.I. Alvarez Retuerto, M. Imielinski, D. Hadley, J.P. Bradfield, C. Kim, N.B. Gidaya, I. Lindquist, T. Hutman, M. Sigman, V. Kustanovich, C. M. Lajonchere, A. Singleton, J. Kim, T.H. Wassink, W.M. McMahon, T. Owley, J.A. Sweeney, H. Coon, J.I. Nurnberger Jr, M. Li, R.M. Cantor, N.J. Minshew, J.S. Sutcliffe, E.H. Cook, G. Dawson, J.D. Buxbaum, S.F.A. Grant, G.D. Schellenberg, D.H. Geschwind and H. Hakonarson: Genome-Wide Analyses of Exonic Copy Number Variants in a Family-Based Study Point to Novel Autism Susceptibility Genes. PLoS Genetics 5: e1000536, 2009 Notes: *equal contribution.

K. Wang, H. Zhang, S. Kugathasan, V. Annese, J.P. Bradfield, R.K. Russell, P.M.A. Sleiman, M. Imielinski, J. Glessner, C. Hou, D.C. Wilson, T. Walters, C. Kim, E.C. Frackelton, P. Lionetti, A. Barabino, J. Van Limbergen, S. Guthery, L. Denson, D. Piccoli, M. Li, M. Dubinsky, M. Silverberg, A. Griffiths, S.F.A. Grant, J. Sansangi, R. Baldassano and H. Hakonarson: Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn's Disease. American Journal of Human Genetics 84(3): 399-405, 2009.

K. Wang*, H. Zhang*, D. Ma*, M. Bucan, J.T. Glessner, B.S. Abrahams, D. Salyakina, M. Imielinski, J.P. Bradfield, P.M.A. Sleiman, C.E. Kim, R. Chiavacci, N. Takahashi, T. Sakurai, E. Rappaport, C.M. Lajonchere, J. Munson, A. Estes, O. Korvatska, J. Piven, L.I. Sonnenblick, A.I. Alvarez Retuerto, E.I. Herman, H. Dong, T. Hutman, M. Sigman, S. Ozonoff, A. Klin, T. Owley, J.A. Sweeney, C.W. Brune, R. Cantor, R. Bernier, J.R. Gilbert, M.L. Cuccaro, T.H. Wassink, W.M. McMahon, H. Coon, J. Miller, J.I. Nurnberger Jr., M.W. State, J.L. Haines, J.S. Sutcliffe, E.H. Cook, N.J. Minshew, J.D. Buxbaum, G. Dawson, S.F.A. Grant, D.H. Geschwind, M.A. Pericak-Vance, G.D. Schellenberg and H. Hakonarson: Common genetic variants on 5p14.1 associate with autism spectrum disorders. Nature 459: 528-533, 2009 Notes: *equal contribution; COVER STORY.

J.T. Glessner, K. Wang, G. Cai, O. Korvatska, C.E. Kim, S. Wood, H. Zhang, A. Estes, C. Brune, J.P. Bradfield, M. Imielinski, E.C. Frackelton, J. Reichert, E.L. Crawford, J. Munson, P. Sleiman, R. Chiavacci, K. Annaiah, K. Thomas, C. Hou, W. Glaberson, J. Flory, F. Otieno, M. Garris, L. Soorya, L. Klei, J. Piven, K.J. Meyer, E. Anagnostou, T. Sakurai, R.M. Game, D.S. Rudd, D. Zurawiecki, C. McDougle, L.K. Davis, J. Miller, D. Posey, S. Michaels, A. Kolevzon, J.M. Silverman, R. Bernier, S.E. Levy, G. Dawson, T. Owley, W.M. McMahon, T.H. Wassink, J.A. Sweeney, J.I. Nurnberger Jr., H. Coon, J.S. Sutcliffe, N.J. Minshew, S.F.A. Grant, M. Bucan, E.H. Cook Jr., J.D. Buxbaum, B. Devlin, G.D. Schellenberg and H. Hakonarson: Autism genome wide copy number variation reveals ubiquitin and neuronal genes. Nature 459: 569-573, 2009 Notes: COVER STORY.

J. Zhao, M. Li, J.P. Bradfield, K. Wang, H. Zhang, P. Sleiman, C.E. Kim, K. Annaiah, W. Glaberson, J.T. Glessner, F.G. Otieno, K.A. Thomas, M. Garris, C. Hou, E.C. Frackelton, R.M. Chiavacci, R.I. Berkowitz, H. Hakonarson and S.F.A. Grant: Examination of type 2 diabetes loci implicates CDKAL1 as a birth weight gene. Diabetes 58: 2414-2418, 2009.

J. Zhao*, J.P. Bradfield*, M. Li, K. Wang, H. Zhang, C.E. Kim, K. Annaiah, J.T. Glessner, K.A. Thomas, M. Garris, E.C. Frackelton, F.G. Otieno, J.L. Shaner, R.M. Smith, R.M. Chiavacci, R.I. Berkowitz, H. Hakonarson and S.F.A. Grant: The role of obesity-associated loci identified in genome wide association studies in the determination of pediatric BMI. Obesity 17: 2254-2257, 2009 Notes: *equal contribution.

J. Flory, P. Sleiman, J. Christi, K. Annaiah, J. Bradfield, C. Kim, J. Glessner, M. Imielinski, H. Li, E. Frackelton, C. Hou, G. Otieno, K. Thomas, R. Smith, W. Glaberson, M. Garris, R. Chiavacci, J. Allen, J. Spergel, R. Grundmeier, M. Grunstein, M. Magnusson, S.F.A. Grant, K. Bønnelykke, H. Bisgaard and H. Hakonarson: 17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early vs late onset asthma in North-Americans of European Ancestry. Journal of Allergy and Clinical Immunology 124: 605-7, 2009.

Imielinski M*, Baldassano RN*, Griffiths A*, Russell RK*, Annese V*, Dubinsky M*, Kugathasan S*, Bradfield JP, Walters TD, Sleiman P, Kim CE, Muise A, Wang K, Glessner JT, Saeed S, Zhang H, Frackelton EC, Hou C, Flory JH, Otieno G, Chiavacci RM, Grundmeier R, Castro M, Latiano A, Dallapiccola B, Stempak J, Abrams DJ, Taylor K, McGovern D; Western Regional Alliance for Pediatric IBD, Silber G, Wrobel I, Quiros A; International IBD Genetics Consortium, Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmuda MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ; NIDDK IBD Genetics Consortium, Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E; Belgian-French IBD Consortium; Wellcome Trust Case Control Consortium, Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwillam R, Tremelling M, Delukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ, Heyman MB, Ferry GD, Kirschner B, Lee J, Essers J, Grand R, Stephens M, Levine A, Piccoli D, Van Limbergen J, Cucchiara S, Monos DS, Guthery SL, Denson L, Wilson DC, Grant SF, Daly M, Silverberg MS*, Satsangi J*, Hakonarson H*.: Common variants at five new loci associated with early-onset inflammatory bowel disease. Nature Genetics 41: 1335-1340, 2009 Notes: *equal contribution.

H.Q. Qu, J.P. Bradfield, S.F.A. Grant, H. Hakonarson, C. Polychronakos and the Type 1 Diabetes Genetics Consortium: Remapping the type 1 diabetes association of the CTLA4 locus. Genes and Immunity 10(S1): S27-S32, 2009.

H.Q. Qu, J.P. Bradfield, A. Bélisle, S.F.A. Grant, H. Hakonarson, C. Polychronakos and the Type 1 Diabetes Genetics Consortium: The type 1 diabetes association of the IL2RA locus. Genes and Immunity 10(S1): S42-S48, 2009.

H. Qu*, S.F.A. Grant*, J.P. Bradfield, C. Kim, E. Frackelton, H. Hakonarson and C. Polychronakos: Association of RASGRP1 with type 1 diabetes is revealed by combined follow-up of two genome-wide studies. Journal of Medical Genetics 46: 553-4, 2009 Notes: *equal contribution.

B.M. Kamath, B.D. Thiel, X. Gai, P.S. Munoz, J. Glessner, D. Clark, D.M. Warthen, T.H. Shaikh, E. Michi, D.A. Picoli, S.F.A. Grant, H. Hakonarson, I.D. Krantz and N.B. Spinner: SNP array mapping of 20p deletions: Genotypes, Phenotypes and Copy Number Variation. Human Mutation 30(3): 371-378, 2009.

2008

S.F.A. Grant, M. Li, J.P. Bradfield, C.E. Kim, K. Annaiah, E. Santa, J.T. Glessner, T. Casalunovo, E.C. Frackelton, F.G. Otieno, J.L. Shaner, R.M. Smith, M. Imielinski, A.W. Eckert, R.M. Chiavacci, R.I. Berkowitz and H. Hakonarson. : Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP. PLoS One 3: e1746, 2008.

S.F.A. Grant, M. Li, J.P. Bradfield, C.E. Kim, K. Annaiah, E. Santa, J.T. Glessner, T. Casalunovo, E.C. Frackelton, F.G. Otieno, J.L. Shaner, R.M. Smith, A.W. Eckert, M. Imielinski, R.M. Chiavacci, R.I. Berkowitz, H. Hakonarson: Association of HMGA2 gene variation with height in specific pediatric age categories. Genomics Insights 1: 13-16, 2008.

S. Kugathasan, R.N. Baldassano, J.P. Bradfield, P.M.A. Sleiman, M. Imielinski, S.L. Guthery, S. Cucchiara, C.E. Kim, E.C. Frackelton, K. Annaiah, J.T. Glessner, E. Santa, T. Willson, A.W. Eckert, E. Bonkowski , J.L. Shaner, R.M. Smith, F.G. Otieno, N. Peterson, D.J. Abrams, R.M. Chiavacci, R. Grundmeier, P. Mamula, G. Tomer, D.A. Piccoli, D.S. Monos, V. Annese, L.A. Denson, S.F.A. Grant and H. Hakonarson: Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. Nature Genetics 40: 1211-1215, 2008.

P.M.A. Sleiman, K. Annaiah, M. Imielinski, J.P. Bradfield, C.E. Kim, E.C. Frackelton, J.T. Glessner, A.W. Eckert, F.G. Otieno, E. Santa, K. Thomas, R.M. Smith, M. Garris, S. Gunnlaugsson, R.M. Chiavacci, J. Allen, J. Spergel, R. Grundmeier, M.M. Grunstein, M. Magnusson, H. Bisgaard, S.F.A. Grant and H. Hakonarson: ORMDL3 variants associated with asthma susceptibility in North Americans of European ancestry. Journal of Allergy and Clinical Immunology 122: 1225-7, 2008.

K. Wang, Z. Chen, M. Tadesse, J. Glessner, S.F.A. Grant, H. Hakonarson, M. Bucan and M. Li: Modeling Genetic Inheritance of Copy Number Variations. Nucleic Acid Research 36: e138, 2008.

J.M. Maris, Y.P. Mosse, J.P. Bradfield, C. Hou, S. Monni, R. Scott, S. Asgharzadeh, E.F. Attiyeh, S.J. Diskin, M. Laudenslager, C. Winter, K. Cole, J.T. Glessner, C. Kim, E.C. Frackelton, T. Casalunovo, A.W. Eckert, M. Capasso, E.F. Rappaport, C. McConville, W.B. London, R.C. Seeger, N. Rahman, M. Devoto, S.F.A. Grant, H. Li and H. Hakonarson: A genome-wide association study identifies a susceptibility locus to clinically aggressive neuroblastoma at 6p22. New England Journal of Medicine 358: 2585-2593, 2008.

H. Qu, S.F.A. Grant, J.P. Bradfield, C.E. Kim, E.C. Frackelton, H. Hakonarson and C. Polychronakos: Association analysis of the type 2 diabetes loci in type 1 diabetes. Diabetes 57: 1983-1986, 2008.

H. Hakonarson, H. Qu, J.P. Bradfield, L. Marchand, C.E. Kim, J.T. Glessner, R. Grabs, T. Casalunovo, S.P. Taback, E.C. Frackelton, A.W. Eckert, K. Annaiah, M.L. Lawson, F.G. Otieno, E. Santa, J.L. Shaner, R.M. Smith, C.C. Onyiah, Y. Lu, R. Skraban, R.M. Chiavacci, L.J. Robinson, C.A. Stanley, S.E. Kirsch, M. Devoto, D.S. Monos, S.F.A. Grant and C. Polychronakos: A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study. Diabetes 57: 1983-1986, 2008.

E. Behrens, T.H. Finkel, J. P. Bradfield, C.E. Kim, L. Linton, T. Casalunovo, E.C. Frackelton, E. Santa, F.G. Otieno, J.T. Glessner, R.M. Chiavacci, S.F.A. Grant and H. Hakonarson: Association of the TRAF1-C5 locus on chromosome 9 with Juvenile Idiopathic Arthritis. Arthritis and Rheumatism 58: 2206-2208, 2008.

B.J. Keating, S. Tischfield, S.S. Murray, T. Bhangale, T.S. Price, J.T. Glessner, L. Galver, J.C. Barrett, S.F.A. Grant, D.N. Farlow, H.R. Chandrupatla, M. Hansen, S. Ajmal, G.J. Papanicolaou, Y. Guo, M. Li, S. DerOhannessian, P.I. W. de Bakker, S.D. Bailey, A. Montpetit, A.C. Edmondson, K. Taylor, X. Gai, S.S. Wang, M. Fornage, T. Shaikh, L. Groop, M. Boehnke, A.S. Hall, A.T. Hattersley, E. Frackelton, N. Patterson, C.W.K. Chiang, C.E. Kim, R.R. Fabsitz, W. Ouwehand, A.L. Price, P. Munroe, M. Caulfield, T. Drake, E. Boerwinkle, D. Reich, A.S. Whitehead, T.P. Cappola, N.J. Samani, A.J. Lusis, , E. Schadt, J.G. Wilson, W. Koenig, M.I. McCarthy, S. Kathiresan, S.B. Gabriel, H. Hakonarson, S.S. Anand, M. Reilly, J.C. Engert, D.A. Nickerson, D.J. Rader, J.N. Hirschhorn and G.A. FitzGerald: Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies. PLoS One 3: e3583, 2008.

2007

R.N. Baldassano, J.P. Bradfield, D.S. Monos, C.E. Kim, J.T. Glessner, T. Casalunovo, E.C. Frackelton, F.G. Otieno, S. Kanterakis, J.L. Shaner, R.M. Smith, A.W. Eckert, L.J. Robinson, C.C. Onyiah, D.J. Abrams, R.M. Chiavacci, R. Skraban, M. Devoto, S.F.A. Grant and H. Hakonarson: Association of the T300A non-synonymous variant of the ATG16L1 gene with susceptibility to paediatric Crohn's disease. Gut 56: 1171-3, 2007.

R.N. Baldassano, J.P. Bradfield, D.S. Monos, C.E. Kim, J.T. Glessner, T. Casalunovo, E.C. Frackelton, F.G. Otieno, S. Kanterakis, J.L. Shaner, R.M. Smith, A.W. Eckert, L.J. Robinson, C.C. Onyiah, D.J. Abrams, R.M. Chiavacci, R. Skraban, M. Devoto, S.F.A. Grant and H. Hakonarson: Association of Variants of the Interleukin-23 Receptor Gene With Susceptibility to Pediatric Crohn's Disease Clinical Gastroenterology and Hepatology 5: 972-6, 2007.

K. Wang, M. Li, D. Hadley, R. Liu, J.T. Glessner, S.F.A. Grant, H. Hakonarson and M. Bucan: PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data. Genome Research 17: 1665-74, 2007.

H. Hakonarson*, S.F.A. Grant*, J.P. Bradfield*, L. Marchand, C.E. Kim, J.T. Glessner, R. Grabs, T. Casalunovo, S.P. Taback, E.C. Frackelton, M.L. Lawson, L.J. Robinson, R. Skraban, Y. Lu, R.M. Chiavacci, C.A. Stanley, S.E. Kirsch, E.F. Rappaport, J.S. Orange, D.S. Monos, M. Devoto, H. Qu and C. Polychronakos: A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. Nature 448: 591-4, 2007 Notes: *equal contribution.

A. Helgason, S. Palsson, G. Thorleifsson, S.F.A. Grant, V. Emilsson, S. Gunnarsdottir, A. Adeyemo, Y. Chen, G. Chen, I. Reynisdottir, R. Benediktsson, A. Hinney, T. Hansen, G. Andersen, K. Borch-Johnsen, T. Jorgensen, H. Schafer, M. Faruque, A. Doumatey, J. Zhou, R.L. Wilensky, M.P. Reilly, D.J. Rader, Y. Bagger, C. Christiansen, G. Sigurdsson, J. Hebebrand, O. Pedersen, U. Thorsteinsdottir, J.R. Gulcher, A. Kong, C. Rotimi and K. Stefansson : Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. Nature Genetics 39: 218-225, 2007.

2006

S.F.A. Grant, G. Thorleifsson, I. Reynisdottir, R. Benediktsson, A. Manolescu, J. Sainz, A. Helgason, H. Stefansson, V. Emilsson, A. Helgadottir, U. Styrkarsdottir, K.P. Magnusson, G. B. Walters, E. Palsdottir, T. Jonsdottir, T. Gudmundsdottir, A. Gylfason, J. Saemundsdottir, R.L. Wilensky, M.P. Reilly, D.J. Rader, Y. Bagger, C. Christiansen, V.Gudnason, G. Sigurdsson, U. Thorsteinsdottir, J.R. Gulcher, A. Kong and K. Stefansson : Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nature Genetics 38: 320-3, 2006 Notes: TOP COVER STORY.

A. Helgadottir, A. Manolescu, A. Helgason, G. Thorleifsson, U. Thorsteinsdottir, D.F. Gudbjartsson, S. Gretarsdottir, K.P. Magnusson, G. Gudmundsson, A. Hicks, T. Jonsson, S.F.A. Grant, J. Sainz, S.J. O'Brien, S. Sveinbjornsdottir, E.M. Valdimarsson, S.E. Matthiasson, A.I. Levey, J.L. Abramson, M.P. Reilly, V. Vaccarino, M.L. Wolfe, V. Gudnason, A.A. Quyyumi, E.J. Topol, D.J. Rader, G. Thorgeirsson, J.R. Gulcher, H. Hakonarson, A. Kong and K. Stefansson: A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. Nature Genetics 38: 68-74, 2006.

2005

T.V. Nguyen, L.M. Esteban, C.P. White, S.F.A. Grant, J.R. Center, E.M. Gardiner, J.A. Eisman: Contribution of the collagen I alpha 1 and vitamin D receptor genes to the risk of hip fracture in elderly women. Journal of Clinical Endocrinology & Metabolism 90: 6575-9, 2005.

A. Helgadottir, S. Gretarsdottir, D. St. Clair, A. Manolescu, J. Cheung, G. Thorleifsson, A. Pasdar, S.F.A. Grant, L. J. Whalley, H. Hakonarson, U. Thorsteinsdottir, A. Kong, J. Gulcher K. Stefansson and M.J. MacLeod: Association between the gene encoding 5-lipoxygenase-activating protein and stroke replicated in a Scottish population. American Journal of Human Genetics 76: 505-9, 2005.

2004

A. Helgadottir, A. Manolescu, G. Thorleifsson, S. Gretarsdottir, H. Jonsdottir, U. Thorsteinsdottir, N.J. Samani, G. Gudmundsson, S.F.A. Grant, G. Thorgeirsson, S. Sveinbjornsdottir, E.M. Valdimarsson, S.E. Matthiasson, H. Johannsson, O. Gudmundsdottir, M.E. Gurney, J. Sainz, M. Thorhallsdottir, M. Andresdottir, M.L. Frigge, E.J. Topol, A. Kong, V. Gudnason, H. Hakonarson, J.R. Gulcher and K. Stefansson : The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nature Genetics 36: 233-9, 2004.

2003

U. Styrkarsdottir, J.B. Cazier, A. Kong, O. Rolfsson, H. Larsen, E. Bjarnadottir, V.D. Johannsdottir, M.S. Sigurdardottir, Y. Bagger, C. Christiansen, I. Reynisdottir, S.F.A. Grant, K. Jonasson, M.L. Frigge, J.R. Gulcher, G. Sigurdsson and K. Stefansson: Linkage of osteoporosis to chromosome 20p12 and association to BMP2. PLoS Biology 1: E69, 2003.

I. Reynisdottir, G. Thorleifsson, R. Benediktsson, G. Sigurdsson, V. Emilsson, A.S. Einarsdottir, E.E. Hjorleifsdottir, G.T. Orlygsdottir, G.T. Bjornsdottir, J. Saemundsdottir, S. Halldorsson, S. Hrafnkelsdottir, S.B. Sigurjonsdottir, S. Steinsdottir, M. Martin, J.P. Kochan, B.K. Rhees, S.F.A. Grant, M.L. Frigge, A. Kong, V. Gudnason, K. Stefansson, J.R. Gulcher: Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34-q35.2. American Journal of Human Genetics 73: 323-35, 2003.

2002

S.F.A. Grant, S. Steinlicht, U. Nentwich, R. Kern, B. Burwinkel and R. Tolle: SNP genotyping on a genome-wide amplified DOP-PCR template. Nucleic Acid Research 30: e125, 2002.

2001

V. Dean, E.E. Hobson, R.A. Aspden, S.F.A. Grant, B. Li, S.P. Robins and S.H. Ralston: A COL1A1 Sp1 binding site polymorphism predisposes to osteoporotic fracture by affecting bone density and quality. Journal of Clinical Investigation 107: 899-907, 2001.

S.F.A. Grant, G. Thorleifsson, M.L. Frigge, J. Thorsteinsson, B. Gunnlaugsdóttir, Á.J. Geirsson, M. Gudmundsson, A. Vikingsson, K. Erlendsson, J. Valsson, H. Jónsson, D.F. Gudbjartsson, K. Stefánsson, J.R. Gulcher and K. Steinsson: The inheritance of rheumatoid arthritis in Iceland. Arthritis and Rheumatism 44: 2247-54, 2001.

M.A. Brown, M.A. Haughton, S.F.A. Grant, A.S. Gunnell, N.K. Henderson and J.A. Eisman: Genetic control of bone density and turnover: role of the collagen 1alpha1, estrogen receptor, and vitamin D receptor genes. Journal of Bone and Mineral Research 16: 758-64, 2001.

2000

S.F.A. Grant, H. Kristjansdottir, K. Steinsson, T. Blöndal, A. Yuryev, K. Stefánsson and J.R. Gulcher: Long PCR detection of the C4A null allele in B8-C4AQ0-C4B1-DR3. Journal of Immunological Methods 244: 41-7, 2000.

1999

R.W. Keen, K.L. Woodford-Richens, S.F.A. Grant, S.H. Ralston, J.S. Lanchbury and T.D. Spector: Association of polymorphism at the type I collagen (COL1A1) locus with reduced bone mineral density, increased fracture risk, and increased collagen turnover. Arthritis and Rheumatism 42: 285-90, 1999.

1998

P. Garnero, O. Borel, S.F.A. Grant, S.H. Ralston and P.D. Delmas: Collagen Ialpha1 Sp1 polymorphism, bone mass, and bone turnover in healthy French premenopausal women: the OFELY study. Journal of Bone and Mineral Research 13: 813-7, 1998.

B.L. Langdahl, S.H. Ralston, S.F.A. Grant and E.F. Eriksen: An Sp1 binding site polymorphism in the COLIA1 gene predicts osteoporotic fractures in both men and women. Journal of Bone and Mineral Research 13: 1384-9, 1998.

A.G. Uitterlinden, H. Burger, Q. Huang, F. Yue, F.E.A. McGuigan, S.F.A. Grant, A. Hofman, J.P.T.M. van Leeuwen, H.A.P. Pols and S.H. Ralston: Relation of alleles of the collagen type Ialpha1 gene to bone density and the risk of osteoporotic fractures in postmenopausal women. New England Journal of Medicine 338: 1016-21, 1998.

1997

R.E. Murray, F. McGuigan, S.F.A. Grant, D.M. Reid and S.H. Ralston: Polymorphisms of the interleukin-6 gene are associated with bone mineral density. Bone 21: 89-92, 1997.

1996

S.F.A. Grant, D.M. Reid, G. Blake, R. Herd, I. Fogelman and S.H. Ralston: Reduced bone density and osteoporosis associated with a polymorphic Sp1 binding site in the collagen type I alpha 1 gene. Nature Genetics 14: 203-5, 1996.

L.A. Houston, S.F.A. Grant, D.M. Reid and S.H. Ralston: Vitamin D receptor polymorphism, bone mineral density, and osteoporotic vertebral fracture: studies in a UK population. Bone 18: 249-52, 1996.

Abstracts

2017

R. Beaumont, Ø. Helgeland, J.P. Bradfield, M. Nodzenski, X. Liu, A.E. Jonsson, G. Zhang, F. Day, V. Karhunen, M. Horikoshi, M.N. Kooijman, R.B. Prasad, T. Aluwahlia, H. Bisgaard, B. Hocher, A.T. Hattersley, T. Hansen, S. Johansson, G. Davey Smith, H. Hakonarson, D. Scholtens, M. Melbye, L. Groop, J.F. Felix, E. Hypponen, M. McCarthy, S. Sebert, M.R. Jarvelin, K. Ong, J.R.B. Perry, T.I.A. Sorensen, L. Muglia, B. Feenstra, W.L. Lowe Jr, S.F. A. Grant, D.A. Lawlor, P.R. Njølstad, Z. Kutalik, D.M. Evans and R.M. Freathy for the Early Growth Genetics Consortium: Genome-wide study identifies potential parent-of-origin effect on birth weight at ANK1-NKX6-3 type 2 diabetes locus. EASD Study Group on Genetics of Diabetes (EASD-SGGD) annual meeting, Leiden, Netherlands 2017.

Books

S.F.A. Grant: Genetics of Childhood Obesity. The Genetics of Obesity. S.F.A. Grant (eds.). Springer, 2013.

Chapters

2016

S.F.A. Grant and Leif Groop: TCF7L2. The Genetics of Type 2 Diabetes and Related Traits. Jose Florez (eds.). Springer, Page: 297-316, April 2016.

S.F.A. Grant: Genetics of Type 2 Diabetes. Metabolic Syndrome: A Comprehensive Textbook. Rexford S. Ahima (eds.). Springer International Publishing, Page: 141-157, January 2016.

Posters and Presentations

2017

R.M. Thomas, P. Mehra, M.E. Johnson, S.F.A. Grant and A.D. Wells: A novel, intergenic enhancer contributes to Il2 gene expression via chromosomal looping. American Association of Immunologists (AAI) annual meeting, Washington DC, USA 2017 Notes: Oral.

R.D. Leslie, R. Mishra, A. Chesi, D.L. Cousminer,  M.I. Hawa, J.P. Bradfield, K.M. Hodge, V.C. Guy, H. Hakonarson, D. Mauricio, N. Schloot, K.B. Yderstræde, B.F. Voight, S. Schwartz, B.O. Boehm and S.F.A. Grant: Contribution Of Type 1 Diabetes And Type 2 Diabetes Loci To The Genetic Etiology Of Adult-Onset Non-Insulin Requiring Autoimmune Diabetes. 111th Annual Meeting of the Association of Physicians of Great Britain & Ireland, London, UK 2017 Notes: Oral.

R.D. Leslie, D.L. Cousminer, R. Mishra, E. Ahlqvist, M.K. Andersen, A. Chesi, J.P. Bradfield, R.E. Pratley, M.R. Rickels, A. Vella, F. Ovalle, R.I. Harris, S. Varvel, P. Froguel, J.T. Lonsdale, D. Mauricio, N.C. Schloot, , B.F. Voight, H. Hakonarson, K. Khunti, C.J. Greenbaum, B.O. Åsvold, K.B. Yderstræde, E.R. Pearson, S. Schwartz, T. Hansen, T. Tuomi, B.O. Boehm, L. Groop and S.F.A. Grant: Genome wide association study of 'latent autoimmune diabetes in adults' provides novel insights into its pathogenesis. IDF 2017 Congress, Abu Dhabi, UAE 2017 Notes: Oral Poster.

R. Mishra, A. Chesi, D.L. Cousminer,  M.I. Hawa, J.P. Bradfield, K.M. Hodge, V.C. Guy, H. Hakonarson, D. Mauricio, N. Schloot, K.B. Yderstræde, B.F. Voight, S. Schwartz, B.O. Boehm, S.F.A. Grant and R.D. Leslie: Relative Contribution of Type 1 Diabetes and Type 2 Diabetes Loci to the Genetic Etiology of Adult-Onset Non-Insulin Requiring Autoimmune Diabetes. JDRF nPOD 9th Annual Scientific Meeting, Fort Lauderdale, USA 2017 Notes: Oral.

R. Beaumont, Ø. Helgeland, R.B. Prasad, J.P. Bradfield, G. Zhang, F. Day, S. Johansson, S. Sebert, K. Ong, J.R.B. Perry, L. Muglia, S.F.A. Grant, P.R. Njølstad, Z. Kutalik, D.M. Evans and R.M. Freathy for the Early Growth Genetics Consortium: Genome-wide study suggests parent-of-origin effect on birth weight at ANK1 type 2 diabetes locus. American Society of Human Genetics, Orlando, USA 2017 Notes: Poster.

M.E. Johnson, E. Manduchi, C. Le Coz, M.E. Leonard, S. Lu, K.M. Hodge, N.D. Romberg, A. Chesi, A.D. Wells and S.F.A. Grant: An ultra-high resolution Capture-C promoter 'interactome' implicates causal genes at SLE GWAS loci. American Society of Human Genetics, Orlando, USA 2017 Notes: Oral.

M. Yau, Y.H. Hsu, A.L. Kuipers, R. Price, S. Tajuddin, S. Handelman, L. Arbeeva, A. Chesi, C.T. Liu, F. Kinyua, W.C. Chou, D. Karasik, R. Joehanes, S. Demissie, L.A. Cupples, B.S. Zemel, S.F.A. Grant, J.M. Jordan, R. Jackson, M. Evans, T. Harris, J. Zmuda and D. Kiel: African Ancestry Ancestry-Specific Genetic Variants for Bone Mineral Density Determination. American Society of Bone and Mineral Research, Denver, USA 2017 Notes: Oral.

M. De Silva, S. Sebert, A. Couto Alves, U. Sovio, S. Das, R.H. Taal, N. Warrington, A.M. Lewin, M. Kaakinen, D. Cousminer, E. Thiering, N. Timpson, V. Karhunen, T. Bond, X. Estivill, V. Lindi, J.P. Bradfield, F. Geller, L.J. M. Coin, M. Loh, S.J. Barton, L.J. Beilin, H. Bisgaard, K. Bønnelykke, R. Alili, T. Ahluwalia, M. Marinelli, I.Y. Millwood, L.J. Palmer, C.E. Pennell, J.R. Perry, S.M. Ring, M. Savolainen, K. Stefansson, F. Rivadeneira, M. Standl, J. Sunyer, C.M.T. Tiesler, A.G. Uitterlinden, I. Prokopenko, K. Herzig, G.D. Smith, J.L. Buxton, A. F. Blakemore, K. Ong, S.F.A. Grant, V.W.V. Jaddoe, P. O'Reilly, M.I. McCarthy and M. Jarvelin for the EGG consortium: Genetic architecture of early growth phenotypes gives insights into their link with later obesity. European Society of Human Genetics, Copenhagen, Denmark 2017 Notes: Poster.

L. Fernández-Rhodes, M. Graff, J. Bradfield, A.E. Justice, Y. Wang, E.J. Parra, M. Cruz, J. Peralta-Romero, A. Audirac-Chalifour, B. Hidalgo, H. Highland, A.G. Comuzzie, N.F. Butte, S.A. Cole, V.S. Voruganti, C. Haiman, R.F. Loos, S.F.A. Grant and K.E. North: The Association of Common Genetic Loci with Childhood Obesity in Hispanic/Latino Children and Adolescents from across the United States and Latin America. American Heart Association Epi Lifestyle 2017, Portland, USA 2017 Notes: Poster.

J.A. Mitchell, D.L. Cousminer, A. Chesi, S.E. McCormack, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, S.F.A. Grant and Babette S. Zemel: High and Low Impact Physical Activity Substitution and Pediatric Bone Density. American College of Sports Medicine annual meeting, Denver, USA 2017 Notes: *Thematic poster; New Investigator Award.

J.A. Mitchell, A. Chesi, S.E. McCormack, D.L. Cousminer, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, Zemel and S.F.A. Grant: Principal component-derived bone density phenotypes and genetic regulation of the pediatric skeleton. Bone Research Society Annual Meeting, Bristol, UK 2017 Notes: Poster.

J.A. Mitchell, A. Chesi, S.E. McCormack, D.L. Cousminer, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, Zemel and S.F.A. Grant: Principal component-derived bone density phenotypes and genetic regulation of the pediatric skeleton. International Conference on Children's Bone Health, Würzburg, Germany 2017 Notes: Oral.

J.A. Mitchell, A. Chesi, S.E. McCormack, D.L. Cousminer, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, B.S. Zemel and S.F.A. Grant: Principal component-derived pediatric bone density phenotypes and genetic regulation of the developing skeleton. 10th World Congress on Development Origins of Health and Disease, Rotterdam, The Netherlands 2017 Notes: Oral Poster.

J.A. Mitchell, A. Chesi, S.E. McCormack, D.L. Cousminer, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, B.S. Zemel and S.F.A. Grant: Integrated pediatric bone density phenotypes and genetic regulation of the developing skeleton. American Society of Human Genetics, Orlando, USA 2017 Notes: Poster.

J. Fu, G. Li, L. Li, J. Yin, H. Chen, L. Han, N. Li, X. Xiao, S.F.A. Grant, S. Gao, M. Li, J. Mi and M. Li: The role of established East Asian obesity-related loci on pediatric leptin levels highlights a neuronal influence on body weight regulation in Chinese Children. American Diabetes Association Scientific Sessions, San Diego, USA 2017 Notes: Poster.

D.L. Cousminer, R. Mishra, E. Ahlqvist, M.K. Andersen, A. Chesi, J.P. Bradfield, R.E. Pratley, M.R. Rickels, A. Vella, F. Ovalle, R.I. Harris, S. Varvel, P. Froguel, J.T. Lonsdale, D. Mauricio, N.C. Schloot, , B.F. Voight, H. Hakonarson, K. Khunti, C.J. Greenbaum, B.O. Åsvold, K.B. Yderstræde, E.R. Pearson, S. Schwartz, T. Hansen, T. Tuomi, B.O. Boehm, L. Groop, R.D. Leslie and S.F.A. Grant: First Genomeâ Wide Association Study of Latent Autoimmune Diabetes in Adults Provides Novel Insights. American Diabetes Association Scientific Sessions, San Diego, USA 2017 Notes: Oral.

D.L. Cousminer, J.A. Mitchell, A. Chesi, S.M. Roy, MD, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, S.E. McCormack, B.F. Voight, B.S. Zemel and S.F.A. Grant: Genetically determined later puberty impacts lowered bone mineral density in childhood and adulthood. 10th World Congress on Development Origins of Health and Disease, Rotterdam, The Netherlands 2017 Notes: Oral.

D.L. Cousminer, A. Chesi, J.A. Mitchell, H.J. Kalkwarf, Joan M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, S.E. McCormack, B.F. Voight, B.S. Zemel and S.F.A. Grant: Longitudinal Genome-Wide Association Analyses and Heritability Estimates of Pediatric Bone Mineral Density. American Society of Human Genetics, Orlando, USA 2017 Notes: Poster.

D. Manousaki, T. Dudding, S. Haworth, Y. Hsu, C. Liu, C. Medina-Gomez, T. Voortman, N. van der Velde, H. Melhus, C. Robinson-Cohen, D.L. Cousminer, M. Nethander, L. Vandenput, R. Noordam, V. Forgetta, L. Lind, E.S. Orwoll, D.O. Mook-Kanamori, K. Michaelsson, B. Kestenbaum, C. Ohlsson, D. Mellstrom, L.C.P.G. de Groot, S.F.A. Grant, D.P. Kiel, M.C. Zillikens, F. Rivadeneira, S. Sawcer, N.J. Timpson and J. B. Richards: Low frequency coding variation in CYP2R1 has large effects on Vitamin D level and risk of multiple sclerosis. American Society of Human Genetics, Orlando, USA 2017 Notes: Oral.

D. Cousminer, A. Chesi, J. Mitchell, H. Kalkwarf, J. Lappe, V. Gilsanz, S. Oberfield, J. Shepherd, A. Kelly, S. McCormack, B. Voight, B. Zemel, S.F.A. Grant: Longitudinal genome-wide association analyses and heritability estimates of pediatric bone mineral density  American Society of Bone and Mineral Research, Denver, USA 2017 Notes: Late-Breaking Poster.

A. Chesi, S.E. McCormack, V.V. Thaker, H. Hakonarson, J.N. Hirschhorn and S.F.A. Grant: Exome Sequencing in African American children with early-onset obesity reveals new insights. American Society of Human Genetics, Orlando, USA 2017 Notes: Poster.

A. Chesi, O. Grgić, C. Medina-Gomez, S.E. McCormack, D.L. Cousminer, J.A. Mitchell, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, S. Mahboubi, K. Trajanoska, V. Jaddoe1, A.G. Uitterlinden, E.B. Wolvius, B.S. Zemel, S.F.A. Grant* and F. Rivadeneira*: A genome-wide association meta-analysis implicates adrenal steroidogenesis in the process of skeletal maturation. American Society of Bone and Mineral Research, Denver, USA 2017 Notes: *equal contribution; Oral.

2016

R.N. Beaumont, Ø. Helgeland, J.P. Bradfield, M. Nodzenski, X. Liu, A.E. Jonsson, F. Day, V. Karhunen, M. Horikoshi, M.N. Kooijman, R.B. Prasad, T. Ahluwalia, G. Zhang, Z. Kutalik, D.M. Evans and R.M. Freathy for the Early Growth Genetics Consortium [of which S.F.A. Grant is a member]: Genome-wide study of parental origin-specific allelic associations with birth weight. American Society of Human Genetics, Vancouver, Canada 2016 Notes: Poster; Reviewers' Choice Abstract.

Q. Xia, A. Chesi, B.T. Johnston, E. Manduchi, S. Li, M.E. Leonard, U.W. Parlin, E.F. Rappaport, P. Huang, A.D. Wells, G.A. Blobel, M.E. Johnson and S.F.A. Grant: Variant to gene mapping reveals that the type 2 diabetes presumed causal variant within TCF7L2 resides in an element controlling the expression of ACSL5 American Diabetes Association Scientific Sessions, New Orleans, USA 2016 Notes: Oral.

M.C.Y. Ng, M. Graff, A. Justice, Y.C. Lu, P. Mudga, C.T. Liu, K. Rand, Q. Duan, B. Cade, J. Brody, M.K. Wojczynski, M.F. Feitosa, L.R. Yanek, J.A. Smith, M.A. Nalls, G. Chen, J. Sha, L. Lange, S. Vedantam, X. Guo, W.M. Chen, A. Chesi, J. Bradfield, D. Huo, B. Padhukasahasram, C. Haiman, R. Loos, K. North, the African ancestry Anthropometry Genetic Consortium [of which S.F.A. Grant is a member]: Identification of Novel Loci Associated with Anthropometric Traits in African Ancestry Populations. American Heart Association Epi Lifestyle 2016, Phoenix, USA 2016 Notes: Poster.

J.A. Mitchell, A. Chesi, S.E. McCormack, S.M. Roy, D.L. Cousminer, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, B.S. Zemel and S.F.A. Grant: A Rare Variant Near EN1 Associates with Pediatric Bone Mass in Females but Not Males. Endocrine Society Annual Meeting, Boston, USA 2016 Notes: Poster.

I. Gandin, P.K. Joshi, T. Esko, J.F. Wilson, The Ygen consortium [of which S.F.A. Grant is a member]: Ygen: the first systematic assessment of the influence of human Y chromosome variation on a wide range of health-related traits. American Society of Human Genetics, Vancouver, Canada 2016 Notes: Poster.

G.P. Way, C.S. Greene and S.F.A. Grant: Incorporating 'topologically associating domain' content in to pathway analyses to implicate causal genes at GWAS loci. American Society of Human Genetics, Vancouver, Canada 2016 Notes: Poster.

D.W Clark, P.K Joshi, I. Gandin, T. Esko and J.F. Wilson for ROHgen [of which S.F.A. Grant is a member]: The scope and mechanism of inbreeding depression in humans. American Society of Human Genetics, Vancouver, Canada 2016 Notes: Poster.

D.L. Cousminer, Rajashree Mishra, Alessandra Chesi, M.I. Hawa, J.P. Bradfield, K.M. Hodge, V.C. Guy, H. Hakonarson, D. Mauricio, N. Schloot, K.B. Yderstræde, B.F. Voight, S. Schwartz, R.D. Leslie, B.O. Boehm and S.F.A. Grant: Relative contribution of type 1 and type 2 genetic risk loci to latent autoimmune diabetes in adults. American Society of Human Genetics, Vancouver, Canada 2016 Notes: Poster; Reviewers' Choice Abstract.

D.L. Cousminer, J.A. Mitchell, A. Chesi, S.M. Roy, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, B.F. Voight, S.E. Oberfield, J.A. Shepherd, A. Kelly, S.E. McCormack, S.F.A. Grant and B.S. Zemel: Individual Variants and Genetic Risk Score for Puberty Timing Associate with Pediatric Bone Mineral Density. American Society of Bone and Mineral Research, Atlanta, USA 2016 Notes: Poster.

D.L. Cousminer, A. Chesi, J.A. Mitchell, S.M. Roy, H.J. Kallwarf, J.M. Lappe, V. Gilsanz, B.F. Voight, S.E. Oberfield, J.A. Shepherd, A. Kelly, S.E. McCormack, B.S. Zemel and S.F.A. Grant: Individual Variants and Genetic Risk Score for Age at Menarche Associate with Pediatric Bone Mineral Density. Endocrine Society Annual Meeting, Boston, USA 2016 Notes: Poster.

D.L. Cousminer, A. Chesi, J.A. Mitchell, S.M. Roy, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A Kelly, S.E. McCormack, B.F. Voight, B.S. Zemel and S.F.A. Grant: Heritability of Bone Mineral Density and Content in Childhood and Adolescence. American Society of Bone and Mineral Research, Atlanta, USA 2016 Notes: Poster; Young Investigator Travel Grant Award.

D.L. Cousminer, A. Arkader, B. F. Voight M. Pacifici and S.F.A. Grant: Assessing the General Population Frequency of Rare Coding Variants in EXT1 and EXT2 Previously Implicated in Hereditary Multiple Exostoses. American Society of Bone and Mineral Research, Atlanta, USA 2016 Notes: Late Breaking Poster.

A. Chesi, J.A. Mitchell, H.J. Kalkwarf, J.P. Bradfield, J.M. Lappe, S.E. McCormack, V. Gilsanz, S.E. Oberfield, H. Hakonarson, J.A. Shepherd, A. Kelly, B.S. Zemel and S.F.A. Grant: A Genome-wide Association Study Identifies Gender Specific Loci Influencing aBMD and BMC at Multiple Skeletal Sites in Children of European Descent. American Society of Bone and Mineral Research, Atlanta, USA 2016 Notes: Poster.

2015

V.C. Guy, A. Chesi, M.I. Hawa, J.P. Bradfield, K.J. Basile, H. Hakonarson, C. Thivolet, D. Mauricio, N.C. Schloot, K.B. Yderstræde, S. Schwartz, R.D. Leslie, B.O. Boehm and S.F.A. Grant: The Role of GWAS-implicated Type 1 and Type 2 Diabetes Loci in the Pathogenesis of Latent Autoimmune Diabetes in Adults (LADA). American Diabetes Association Scientific Sessions, Boston, USA 2015 Notes: Oral.

S.M. Roy, J.G. Spivack, M.S. Faith, A. Chesi, J.A. Mitchell, S.F.A. Grant, B.S. Zemel and S.E. McCormack: Concordance Between Weight-for-Length and BMI Under Age 2 Years in a Large, Longitudinal, Multi-Ethnic Cohort. Endocrine Society Annual Meeting, San Diego, USA 2015 Notes: Presidential Poster; 2015 Endocrine Scholars Award in Growth Hormone Research.

S.M. Roy, J.G. Spivack, M.S. Faith, A. Chesi, J.A. Mitchell, S.F.A. Grant, B.S. Zemel and S.E. McCormack: Concordance Between Weight-for-Length and BMI Under Age 2 Years in a Large, Longitudinal, Multi-Ethnic Cohort. CHOP Poster Day, Philadelphia, USA 2015 Notes: Clinical Research Poster Award.

S.E. McCormack, S. Roy, A. Chesi, J.A. Mitchell, H.J. Kwalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, S.F.A. Grant and B.S. Zemel: Skeletal Maturation, Population Ancestry, and Body Composition in Non-Obese, Pre-Pubertal Children. Endocrine Society Annual Meeting, San Diego, USA 2015 Notes: Late Breaking Poster.

S. Lu, S.E. Mccormack, Q. Xia, M.J. Falk and S.F.A. Grant: Insights from Functional Analysis of the TCF7L2 locus: PARP-1 Inhibition Rescues Glucose-induced Shortened Lifespan in Caenorhabditis elegans. American Diabetes Association Scientific Sessions, Boston, USA 2015 Notes: Poster.

S. Lu, S.E. McCormack, Q. Xia, M.J. Falk and S.F.A. Grant: Insights from Functional Analysis of the TCF7L2 locus: PARP-1 inhibition rescues glucose-induced shortened lifespan in Caenorhabditis elegans. CHOP Poster Day, Philadelphia, USA 2015 Notes: Poster.

R.D. Leslie, A. Chesi, V.C. Guy, M.I. Hawa, J.P. Bradfield, H. Hakonarson, C. Thivolet, D. Mauricio, N. Schloot, K.B. Yderstræde, S. Schwartz, B.O. Boehm and S.F.A. Grant: GWAS-implicated in type 1 and type 2 diabetes loci: insight into their relative roles in the pathogenesis of Latent Autoimmune Diabetes in Adults (LADA). European Association for the Study of Diabetes, Stockholm, Sweden 2015 Notes: Poster.

R. Thomas, M. Johnson, S.F.A. Grant and A. Wells: Role of DNMT3a in establishing the lineage-specific DNA methylome of differentiating T cells. Keystone "T Cells: Regulation and Effector Function", Snowbird, USA 2015 Notes: Poster.

Q. Xia, S. Lu, B.T. Johnston, M.E. Johnson, K.J. Basile and S.F.A. Grant: Gene Editing of the Key Genomic Element within TCF7L2 Using the CRISPR/Cas9 System Reveals an Impact on Gene Expression and Splice Isoform Repertoire. American Diabetes Association Scientific Sessions, Boston, USA 2015 Notes: Poster (Audio Guide).

Q. Xia, S. Lu, B.T. Johnston, M.E. Johnson, K.J. Basile and S.F.A. Grant: Gene editing of the key genomic element within TCF7L2 using the CRISPR/Cas9 system reveals an impact on gene expression and splice isoform repertoire. CHOP Poster Day, Philadelphia, USA 2015 Notes: Poster.

M.E. Johnson, U.W. Parlin, K.J. Basile, B.T. Johnston, Q. Xia, V. Guy, J. Sainz, A.D. Wells and S.F.A. Grant: The Endocrine Disruptors, Bisphenol A and Diethylhexyl Phthalate, Perturb Key Molecular Pathways Based on Analyses of TCF7L2 Genomic Occupancy Patterns. UPenn Epigenetics and Metabolism Symposium, Philadelphia, USA 2015 Notes: Poster.

M.E. Johnson, U.W. Parlin, K.J. Basile, B.T. Johnston, Q. Xia, V. Guy, J. Sainz, A.D. Wells and S.F.A. Grant: The Endocrine Disruptors, Bisphenol A and Diethylhexyl Phthalate, PerturbKey Molecular Pathways Based on Analyses of TCF7L2 Genomic Occupancy Patterns. Endocrine Society Annual Meeting, San Diego, USA 2015 Notes: Poster.

M.E. Johnson, U.W. Parlin, K.J. Basile, B.T. Johnston, Q. Xia, V. Guy, J. Sainz, A.D. Wells and S.F.A. Grant: The Endocrine Disruptors, Bisphenol A and Diethylhexyl Phthalate, Perturb Key Molecular Pathways Based on Analyses of TCF7L2 Genomic Occupancy Patterns. CHOP Poster Day, Philadelphia, USA 2015 Notes: Poster.

M.E. Johnson*, Q. Xia*, A. Chesi*, B.T. Johnston, S. Lu, E.F. Rappaport, P. Huang, A.D. Wells, G.A. Blobel and S.F.A. Grant: The genomic region harboring the type 2 diabetes presumed causal variant within TCF7L2 forms long‐range functional connections with ACSL5. American Society of Human Genetics, Baltimore, USA 2015 Notes: Oral.

M. Horikoshi, L. Carstensen, D.P. Strachan, M.N. Kooijman, E.T.H. Boh, P.K. Joshi, E.M. Van Leeuwen, J.P. Bradfield, N. Pitkänen, L.P. Lyytikäinen, V. Lindi, R. Joro, E. Kreiner-Møller, E. Thiering, R. Rueedi, W. Ang, C. Wang, I. Ntalla, Y. Wu, N. Vilor-Tejedor, D.L. Cousminer, T.S. Ahluwalia, V. Lagou, N. Grarup, C.T.H. Have, A. Mahajan, N.J. Timpson, M.I. Mccarthy, R.M. Freathy, A.P. Morris on behalf of the EGG Consortium [of which S.F.A. Grant is a member]: Large Scale Genome-Wide Association Study for Birth Weight Finds Eight Novel Loci Extending the Genetic Link between Early Growth and Type 2 Diabetes. American Diabetes Association Scientific Sessions, Boston, USA 2015 Notes: Oral.

M. Bustamante, M. Standl, N. Vilor-Tejedor, C. Bonilla, C. Medina-Gomez, J. Curtin, T. Ahluwalia, J.P. Bradfield, J. Bacelis, C.M.T. Tiesler, S.M. Ring, J. Kiefte-de Jong, E. Kreiner-Møller, F.D. Mentch, A. Jugessur, M.M. Brennan, H.A. Moll, B. Jacobsson, N.H. Vissing, V. W. V. Jaddoe, S.F.A. Grant, H. Bisgaard, A. Custovic, F. Rivadeneira, K. Northstone, J. Heinrich, X. Estivill and J. Sunyer: A genome-wide association meta-analysis of gastroenteritis in children. European Society of Human Genetics, Glasgow, UK 2015 Notes: Poster.

K.J. Basile, A. Chesi, J.A. Mitchell, S.E. McCormack, S.M. Roy, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, B.S. Zemel and S.F.A. Grant: Multiple GWAS-Implicated Adult Height Loci Operate in the Context of Pediatric Bone Mineral Density and Content Determination. Endocrine Society Annual Meeting, San Diego, USA 2015 Notes: Late Breaking Oral.

K. Uchibe, A. DiRocco, M. Johnson, S. Sinha, C. Larmour, S.F.A. Grant, M. Pacifici, M. Enomoto-Iwamoto and M. Iwamoto: Retinoic Acid Receptor Gamma Agonists Promote Endochondral Ossification And Facilitate Cartilage-to-Bone Transition Together With beta-catenin-Lef/Tcf Signaling. American Society of Bone and Mineral Research, Seattle, USA 2015 Notes: Plenary poster.

J.P. Bradfield, J.F. Felix, V.W.V. Jaddoe and S.F.A. Grant on behalf of the Early Growth Genetics Consortium: A Trans-Ethnic Meta-analysis of Genome-Wide Association Studies Reveals New Loci Associated with Childhood Obesity. European Association for the Study of Diabetes, Stockholm, Sweden 2015 Notes: Oral.

J.P. Bradfield, J.F. Felix, V.W.V. Jaddoe and S.F.A. Grant on behalf of the Early Growth Genetics Consortium: A Trans-Ethnic Meta-analysis of Genome-Wide Association Studies Reveals New Loci Associated with Childhood Obesity. American Diabetes Association Scientific Sessions, Boston, USA 2015 Notes: Oral.

J.M. Lane, A.C. Bjonnes, B. Cade, S.A. Gharib, S.F.A. Grant, D.S. Lauderdale, N.M. Punjabi, N. Santhi, P.C. Zee, D. Gottlieb, F.A.J.L. Scheer, S.Redline and R. Saxena: Pleiotropic effect of a genetic risk score for obesity on excessive daytime sleepiness in 9,832 individuals of European ancestry from the CARe study. Sleep 2015, Seattle, USA 2015 Notes: Poster.

J.A. Mitchell, A. Chesi, O. Elci, S.E. McCormack, S.M. Roy, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, S.F.A. Grant* and B.S. Zemel*: Pediatric bone density is influenced by physical activity and genetic variation at known bone density loci. American Society of Bone and Mineral Research, Seattle, USA 2015 Notes: Oral; Young Investigator Travel Grant.

J.A. Mitchell, A. Chesi, O. Elci, S.E. McCormack, S.M. Roy, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, S.F.A. Grant and B.S. Zemel: The benefits of physical activity on bone density in childhood are dependent on genetic variation at known bone density loci. CSHL Exercise Science & Health, Cold Spring Harbor, USA 2015 Notes: Oral.

J.A. Mitchell, A. Chesi, O. Elci, S.E. McCormack, S.M. Roy, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, B.S. Zemel and S.F.A. Grant: The Skeletal Benefits of Physical Activity in Childhood Are Dependent on Genetic Variation at Known Bone Density Loci. Endocrine Society Annual Meeting, San Diego, USA 2015 Notes: Oral.

J.A. Mitchell, A. Chesi, K.K. Winer, S.E. McCormack, S.M. Roy, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, S.F.A. Grant and B.S. Zemel: Skeletal benefits of physical activity in childhood may be greatest for males with lower bone mineral content (BMC) and density (BMD). Pediatric Bone and Mineral Working Group, American Society of Bone and Mineral Research, Seattle, USA 2015 Notes: Oral.

J. Tyrrell, R.C. Richmond, T.M. Palmer, B. Feenstra, J. Rangarajan, S. Metrustry, A. Cavadino, L. Paternoster, L.L. Armstrong, N.M.G. De Silva, A.R. Wood, F. Geller, J.P. Bradfield, E. Kreiner-Møller, V. Huikari, J.N. Painter, J.J. Hottenga,, D.J. Berry, S. Das, D.M. Evans, H. Hakonarson, M. G. Hayes, J. Heikkinen, B. Knight, P.A. Lind, G. McMahon, S.E. Medland, M. Melbye, S.M. Ring, S. Sebert, T.I.A. Sørensen, G. Willemsen, E.J.C. de Geus, N.G. Martin, T.D. Spector, C. Power, M.R. Järvelin, H. Bisgaard, S.F.A. Grant, E.A. Nohr, J.C. Murray, A.T. Hattersley, D.M. Scholtens, G. Davey Smith, E. Hyppönen, W.L. Lowe, Jr., T.M. Frayling, D.A. Lawlor and R.M. Freathy: Genetic analyses to test for a causal relationship between maternal thyroid function and offspring birth weight. Mendelian Randomization Conference, Bristol, UK 2015 Notes: Oral.

J. Kemp, C. Medina-Gomez, A. Chesi, C. Wang, J. Eriksson, N.M. Warrington, V.W.V. Jaddoe, B.S. Zemel, K. Zhu, L. Vandenput, B. St. Pourcain, N.J. Timpson, A.G. Uitterlinden, J. Walsh, S. Lye, M. Lorentzon, G. Davey-Smith, C. Ohlsson, C. Pennell, S.F.A. Grant, J.H. Tobias, F. Rivadeneira and D.M. Evans: Genome-wide association study of bone mineral density, content and area measured at the axial and appendicular skeleton identifies four novel loci and suggests a possible reason why genetic loci are associated with bone mineral density at some sites but not others. American Society of Bone and Mineral Research, Seattle, USA 2015 Notes: Poster.

C. Medina-Gómez, A. Chesi, D.H. Heppe, B.S. Zemel, J.L. Yin, H.J. Kalkwarf, A. Hofman, J.M. Lappe, A. Kelly, M. Kayser, S.E. Oberfield, V. Gilsanz, A.G. Uitterlinden, J.A. Shepherd, V.W. Jaddoe, S.F.A. Grant, O. Lao and F. Rivadeneira: BMD loci underlie developmental determination of ethnic differences in skeletal fragility across populations due to selection pressures. CSHL The Biology of The Genome, Cold Spring Harbor, USA 2015 Notes: Oral.

C. Medina-Gomez, J.P. Kemp, E. Kreiner-Møller, A. Chesi, D.H.M. Heppe, B.S. Zemel, K. Bønnelykke, H. Bisgaard, V.W.V. Jaddoe, A.G. Uitterlinden, J.H. Tobias, G. Duque, S.F.A. Grant, D.M. Evans and F. Rivadeneira: Variants in regulatory regions of SREBF1, a Lamin A interaction factor exert pleiotropic effects on BMD and lean mass in children. American Society of Bone and Mineral Research, Seattle, USA 2015 Notes: Poster.

C. Medina-Gomez, J. Kemp, A. Chesi, E. Kreiner-Møller, T. Ahluwalia, D. Mook, Y. Liu, F.P. Hartwig, D. Evans, R. Joro, C. van Duijn, I. Nedeljkovic, J. Eriksson, B. Richards, R. Jackson, D. Karasik, N. Van der Velde, A. Hofman, B. Zemel, B. Mullin, T. Harris, Y. Zhou, J. Robins, R. Li, B. Psaty, C. Nielson, W. Scott, B.L. Horta, T. Lakka, S.F.A. Grant, F. McGuigan, J. Wilson, U. Styrkársdóttir, D. Koller, K. Zhu, D. Kiel, C. Ohlsson, A.G. Uitterlinden, V. Jaddoe, J.H. Tobias, D.M. Evans and F. Rivadeneira: GWAS meta-analysis for total body BMD unveils 14 new BMD loci and variants exerting age-specific effects. American Society of Bone and Mineral Research, Seattle, USA 2015 Notes: Late-breaking poster.

C. Medina-Gomez, A. Chesi, D.H.M. Heppe, B.S. Zemel, J. Yin, H.J. Kalkwarf, A. Hofman, J.M. Lappe, A. Kelly, M. Kayser, S.E. Oberfield, V. Gilsanz, A.G. Uitterlinden1, J.A. Shepherd, V.V.W. Jaddoe, S.F.A. Grant, O. Lao and F. Rivadeneira: BMD loci underlie developmental determination of ethnic differences in skeletal fragility across populations due to selection pressures. European Society of Human Genetics, Glasgow, UK 2015 Notes: Poster.

A. Chesi, V.C. Guy, M.I. Hawa, J.P. Bradfield, K.J. Basile, H. Hakonarson, C. Thivolet, D. Mauricio, N. Schloot, K.B. Yderstræde, S. Schwartz, R.D. Leslie, B.O. Boehm and S.F.A. Grant.: The role of GWAS-implicated type 1 and type 2 diabetes loci in the pathogenesis of latent autoimmune diabetes in adults (LADA). CSHL The Biology of The Genome, Cold Spring Harbor, USA 2015 Notes: Poster.

A. Chesi, Sani M. Roy, J.A. Mitchell, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, S. Mahboubi, K. Winer, A. Kelly, S.F.A. Grant, B.S. Zemel and S. McCormack: Skeletal Maturation and Population Ancestry in Non-Obese, Pre-Pubertal Children. American Society of Bone and Mineral Research, Seattle, USA 2015 Notes: Oral.

A. Chesi, J.A. Mitchell, K.J. Basile, S.E. McCormack, S.M. Roy, H.J. Kalkwarf, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, A. Kelly, B.S. Zemel and S.F.A. Grant: Multiple GWAS-Implicated Adult Height Loci Operate in the Context of Pediatric Bone Mineral Density and Content Determination. American Society of Bone and Mineral Research, Seattle, USA 2015 Notes: Plenary Poster.

A. Chesi, J. Mitchell, H.J. Kalkwarf, J.P. Bradfield, J.M. Lappe, O. Elci, S.E. McCormack, V. Gilsanz, S.E. Oberfield, H. Hakonarson, J.A. Shepherd, A. Kelly, B.S. Zemel and S.F.A. Grant: A trans-ethnic genome-wide association study identifies gender specific loci influencing pediatric BMD and BMC at the distal radius. CHOP Poster Day, Philadelphia, USA 2015 Notes: Poster.

A. Chesi, H.J. Kalkwarf, F.D. Mentch, J.M. Lappe, V. Gilsanz, S.E. Oberfield, J.A. Shepherd, J.P. Bradfield, S. Mahboubi, S.M. Roy, J.A. Mitchell, R.M. Chiavacci, A. Kelly, H. Hakonarson, B.S. Zemel, S.F.A. Grant and S.E. McCormack: Loci Influencing Skeletal Age in Children and Adolescents Identified through a Trans-Ethnic Appraisal of Both Common and Rare Genetic Variants. Endocrine Society Annual Meeting, San Diego, USA 2015 Notes: Poster.

Invited Lectures

2017

S.F.A. Grant. "Variant to gene mapping in metabolic traits", Philadelphia Obesity Research Day, Philadelphia, USA, May, 2017.

2016

S.F.A. Grant. "How do we make findings from GWAS actionable?", c-BIG Symposium, Singapore, Nov, 2016.

S.F.A. Grant. "GWAS only finds signals; 3D genomics finds the genes", Summer School on Diabetes and Metabolism, Ebberup, Denmark, Sep, 2016.

S.F.A. Grant. "TCF7L2 locus: lots of smoke but how much fire?", Symposium on "Genetics and metabolism: a decade later", Plenary lecture, 52nd EASD Annual Meeting, Munich, Germany, Sep, 2016.

S.F.A. Grant. "GWAS only finds signals; 3D genomics finds the genes", 20th Congress of the European Anthropological Association, Zagreb, Croatia, Aug, 2016.

S.F.A. Grant. "How do we make findings from GWAS actionable?", Lund University, Lund, Sweden, Apr, 2016.

S.F.A. Grant. "Genetics of childhood obesity", NovoNordisk Foundation symposium: 'Early growth genetics and metabolic diseases - Integrated mechanisms and translational perspectives', Hellerup, Denmark, Apr, 2016.

S.F.A. Grant. "How do we make findings from GWAS actionable?", Oregon Health & Science University, Portland, USA, Mar, 2016.

2015

S.F.A. Grant. "Genetic Determinants of Bone Mass", 'Determinants of Peak Bone Mass' NIH Workshop, Bethesda, USA, Nov, 2015.

S.F.A. Grant. "How do we make findings from GWAS actionable?", Stanford University School of Medicine, Stanford, USA, Nov, 2015.

S.F.A. Grant. "GWAS only finds signals; 3D genomics finds the genes", Cincinnati Children's Hospital Medical Center, Cincinnati, USA, Oct, 2015.

S.F.A. Grant. "Obesity and type 2 diabetes ARE genetic", St Andrews Society, Philadelphia, USA, Oct, 2015.

S.F.A. Grant. "GWAS only finds signals; 3D genomics finds the genes", Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark, Sep, 2015.

S.F.A. Grant. "Genetics of Type 2 Diabetes-from Insights to Applications", 'Monogenic Diabetes' symposium, American Diabetes Association Scientific Sessions, Boston, USA, Jun, 2015.

S.F.A. Grant. Debate participant, Advances in Mineral Metabolism Meeting, Snowmass, USA, Apr, 2015.

S.F.A. Grant. "Genome wide association studies and what we still don't know", Department of Surgery Research Seminar Series, Thomas Jefferson University, Philadelphia, USA, Mar, 2015.

S.F.A. Grant. "A Study of the Genetic Causes of Latent Autoimmune Diabetes in Adults (LADA)", T1D Exchange Biobank Research Meeting, San Diego, USA, Mar, 2015.

Awards and Honors

2016, Croatian Academy of Sciences and Arts, Honorary Member
2011, Russell A. Hibbs Basic Science Award, Scoliosis Research Society
1995, Young Investigator Award, American Society of Bone and Mineral Research, Baltimore

Editorial and Academic Positions

Academic and Institutional Committees

2017-present, GRIN Scientific Working Group, CHOP
2016-2019, Institutional Biobanking Committee, CHOP
2015-present, BioRepository Advisory Committee, CHOP
2015-present, Institutional Intellectual Property Advisory Committee (iiPAC), Chair, CHOP
2014-present, UPenn Advisory Committee for Next Generation Sequencing
2013-present, Co-Leader, Spatial and Functional Genomics Research Affinity Group, CHOP
2010-present, Genomics and Computational Biology, UPenn School of Medicine
2010-present, Cell & Molecular Biology Graduate Group, UPenn School of Medicine
2007-present, Institutional Intellectual Property Advisory Committee (iiPAC), CHOP

Editorial Positions

2017-present, JBMR Plus, Inaugural Editorial Board member
2016-2018, Journal of Bone and Mineral Research, Editorial Board member
2014-present, Pediatric Obesity, Associate Editor
2014-2016, Diabetes, Editorial Board member

Ad Hoc Reviewer

New England Journal of Medicine
Nature
JAMA
Nature Genetics
Gastroenterology
Annals of Internal Medicine
Science Translational Medicine
Lancet Diabetes & Endocrinology
Endocrine Reviews
Circulation Research
AJHG
Arthritis and Rheumatism
Diabetes Care
Diabetes
PLoS Genetics
Diabetologia
Human Molecular Genetics
Journal of Bone and Mineral Research
Human Genetics
Sleep
EJHG
Bone
Obesity
ATVB

Leadership and Memberships

Memberships in Professional Organizations

International

2017-present, International Scientific Advisory Board, DynaHEALTH
2015-present, Ygen consortium
2013-present, Runs of homozygosity genetics (ROHgen) consortium
2011-present, International Scoliosis Genetics Interest Group
2009-present, Early Growth Genetics Consortium (EGG)

National

2016-present, Society of Pediatric Research
2014-2017, Endocrine Society
2013-present, African Ancestry Anthropometry Genetics Consortium (AAAGC)
2010-present, American Society of Bone and Mineral Research
2009-present, American Diabetes Association
 - 2014-2016, Reviewer, American Diabetes Association's Research Grant Review Committee
2008-present, American Society of Human Genetics