Lawrence B. Holzman, MD

Lawrence B. Holzman, MD

Lawrence B. Holzman, MD, is an attending physician in the Glomerular Disease Clinic at Children's Hospital of Philadelphia.

Areas of expertise: Glomerular disease, Systemic vasculitis, Systemic lupus erythematosis


215-590-2449

About Lawrence B. Holzman, MD

Titles

Attending Physician

Education & training

Undergraduate Degree

BA in Biophysics - University of Pennsylvania, Philadelphia, Pennsylvania

 

 


 

Medical Degree

MD UMDNJ - New Jersey Medical School, Newark, New Jersey

Team affiliations

 View fewer all team affiliations View all all team affiliations

Publications

Selected Publications

2015

Spinale Joann M, Mariani Laura H, Kapoor Shiv, Zhang Jidong, Weyant Robert, Song Peter X, Wong Hetty N, Troost Jonathan P, Gadegbeku Crystal A, Gipson Debbie S, Kretzler Matthias, Nihalani Deepak, Holzman Lawrence B: A reassessment of soluble urokinase-type plasminogen activator receptor in glomerular disease. Kidney international 87(3): 564-74, Mar 2015.

2013

Gadegbeku CA, Gipson DS, Holzman LB, Ojo AO, Song PXK, Barisoni L, Sampson MG, Kopp JB, Lemley KV, Nelson PJ, Lienczewski CC, Adler SG, Appel GB, Cattran DC, Choi MJ, Contreras G, Dell KM, Fervenza FC, Gibson KL, Greenbaum LA, Hernandez JD, Hewitt SM, Hingorani SR, Hladunewich M, Hogan MC, Hogan SL, Kaskel FJ, Lieske JC, Meyers KEC, Nachman PH, Nast CC, Neu AM, Reich HN, Sedor JR, Sethna CB, Trachtman H, Tuttle KR, Zhdanova O, Zilleruelo GE, Kretzler M: Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach. Kidney Int 83(4): 749-56, Apr 2013.

2012

George B, Verma R, Soofi AA, Garg P, Zhang J, Park T, Giardino L, Ryzhova L, Johnstone DB, Wong H, Nihalani D, Salant DJ, Hanks SK, Curran T, Rastaldi MP, and Holzman LB: Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mice. J Clin Invest 122(2): 674-92, Feb 2012.

2007

Deepak N, Wong H, Verma R, Holzman LB: Src Family Kinases Directly Regulate JIP1 Module Dynamics and Activation. Mol Cell Biol 27(7): 2431-2441, 2007.

2006

Verma R, Kovari I, Abdul S, Nihalani D, Patrie K, Holzman LB: Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization. J Clin Invest 116(5): 1346-1359, 2006.

2005

Moeller MJ, Soofi A, Sanden S, Floege J, Kriz W, Holzman LB: An efficient system for tissue-specific over-expression of transgenes in podocytes in vivo. Am J Physiol Renal Physiol 289(2): F481-F488, 2005.

2004

Moeller MJ, Soofi A, Watzel C, Kriz W, Holzman LB : Protocadherin FAT1 binds Ena/VASP and is necessary for lamellipodial dynamics, cell polarization, and cell migration. EMBO J 23(19): 3769-3779, Oct 2004.

2001

Nihalani D, Meyer D, Pajni S, Holzman LB: Mixed lineage kinase-dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components. EMBO J 20(13): 3447-3458, 2001.

1999

Holzman LB, St. John P, Kovari I, Verma R, Holthofer H, Abrahamson D: Nephrin is localized to the slit pore of the glomerular epithelial cell. Kidney Intl 56(4): 1481-1491, 1999.

1994

Holzman LB, Merritt S, Fan G: Identification, molecular cloning, and characterization of Dual Leucine Zipper Kinase: a novel serine/threonine kinase that defines a second subfamily of MLK kinases. J Biol Chem 269(49): 30808-30817, 1994.