Alexander R. Judkins, MD

Alexander R. Judkins, MD

Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Background

Lab Expertise

Translation research techniques including tissue microarrays (TMA), digital pathology, pathology informatics and tissue banking.

Clinical Expertise

Pediatric neuropathology with special interest in pathology of central nervous system tumors in infants and children.

Education and Training

Medical School

University of Rochester School of Medicine, Rochester, NY

Internship

Hospital of the University of Pennsylvania, Philadelphia, Pa.

Residency

Anatomic Pathology, Hospital of the University of Pennsylvania, Philadelphia, Pa.

Fellowship

Anatomic Pathology and Neuropathology, Hospital of the University of Pennsylvania, Philadelphia, Pa
Forensic Pathology, Office of Medical Examiner, City of Philadelphia, Pa.

Board Certification

American Board of Pathology/Anatomic Pathology
American Board of Pathology/Forensic Pathology
American Board of Pathology/Neuropathology

Undergraduate Degree

BA, SUNY Geneseo

Titles and Academic Titles

Chief, Division of Neuropathology

Director, Pathology Core Laboratory

Assistant Professor of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania

Research Interests

Diagnosis and molecular characterization of pediatric brain tumors

CHOP Research Institute summary

 

Publications

Papers

 2010

Judkins AR, Ellison DW. Ependymoblastoma: dear, damned, distracting diagnosis, farewell!*. Brain Pathol. 2010 Jan;20(1):133-9. Epub 2008 Dec 17. Read abstract

Heuer GG, Kiefer H, Judkins AR, Belasco J, Biegel JA, Jackson EM, Cohen M, O'Malley BW Jr, Storm PB. Surgical treatment of a clival-C2 atypical teratoid/rhabdoid tumor. J Neurosurg Pediatr. 2010 Jan;5(1):75-9. Read abstract.

2009

Guzman M, Judkins AR. Digital pathology: a tool for 21st century neuropathology. Brain Pathology 19(2): 305-316, April 2009.

Judkins AR. Computer- and Internet-based tools for neuropathology in the 21st century. Brain Pathol. 2009 Apr;19(2):303-4. Epub 2009 Feb 3. No abstract available.

Sievert AJ, Jackson EM, Gai X, Hakonarson H, Judkins AR, Resnick AC, Sutton LN, Storm PB, Shaikh TH, Biegel JA. Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. Brain Pathol. 2009 Jul;19(3):449-58. Epub 2008 Oct 21. Erratum in: Brain Pathol. 2009 Jul;19(3):550.  Read abstract.

2008

Schessl J, Zou Y, McGrath MJ, Cowling BS, Maiti B, Chin SS, Sewry C, Battini R, Hu Y, Cottle DL, Rosenblatt M, Spruce L, Ganguly A, Kirschner J, Judkins AR, Golden JA, Goebel HH, Muntoni F, Flanigan KM, Mitchell CA, Bönnemann CG. Proteomic identification of FHL1 as the protein mutated in human reducing body myopathy. J Clin Invest. 2008 Mar;118(3):904-12. Read abstract.

Winter C, Pawel B, Seiser E, Zhao H, Raabe E, Wang Q, Judkins AR, Attiyeh E, Maris JM. Neural cell adhesion molecule (NCAM) isoform expression is associated with neuroblastoma differentiation status. Pediatr Blood Cancer. 2008 Jul;51(1):10-6. Read abstract.

Judkins AR, Ellison DW. Ependymoblastoma: dear, damned, distracting diagnosis, farewell! Brain Pathology Dec 17. [Epub ahead of print] 2008

2007

Judkins AR. Immunohistochemistry of INI1 expression: a new tool for old challenges in CNS and soft tissue pathology. Adv Anat Pathol 14(5): 335-9, 2007

2005

Judkins AR, Burger PC, Hamilton RL,Kleinschmidt-DeMasters B, Perry A, Pomeroy SL, Rosenblum MK, Yachnis AT, Zhou H, Rorke LB, Biegel JA. INI1 protein expression distinguishes atypical teratoid/rhabdoid tumor from choroid plexus carcinoma. J Neuropathol Exp Neurol 64(5): 391-7, 2005.

2004

Judkins AR, Mauger J, Ht A, Rorke LB, Biegel JA. Immunohistochemical analysis of hSNF5/INI1 in pediatric CNS neoplasms. Am J Surg Pathol 28(5): 644-50, 2004.

 

 

 

 

Books

2009

Louis DN, Frosch MP, Mena H, Rushing EJ, Judkins AR. Non-neoplastic Disease of the Central Nervous System. First Non-Neoplastic Disease Fascicle Series. Armed Forces Institute of Pathology. American Registry of Pathology, Silver Spring, MD. 2009 (in press).

2007

Judkins AR, Eberhart CE, Wesseling P. Cavenee W, Louis DN, Ohgaki H, Wiestler O (eds.). Atypical Teratoid / Rhabdoid Tumor. World Health Organization Classification of Tumors. Pathology & Genetics: Tumors of the Nervous System, 4th edition. 2007. IARC Press, Lyon, France.

Wesseling P, Biegel J, Eberhart C, Judkins AR, Cavenee W, Louis DN, Ohgaki H, Wiestler O. (eds.).  Rhabdoid Tumor Predisposition Syndrome (RTPS). World Health Organization Classification of Tumors. Pathology & Genetics: Tumors of the Nervous System, 4th edition.  2007. IARC Press, Lyon, France.

McLendon RE, Judkins AR, Fuller G, Sarkar C, Ng H, Cavenee W, Louis DN, Ohgaki H, Wiestler O. (eds). CNS primitive neuroectodermal tumour (PNET). World Health Organization Classification of Tumors. Pathology & Genetics: Tumors of the Nervous System, 4th edition.  2007. IARC Press, Lyon, France.