Jennifer M. Lynch, MD, PhD

Papers

2021

Lynch JM, Mavroudis CD, Ko TS, Jacobwitz M, Busch DR, Xiao R, Nicolson SC, Montenegro LM, Gaynor JW, Yodh AG, Licht DJ, Association of ongoing cerebral oxygen extraction during deep hypothermic circulatory arrest with post-operative brain injury. Seminars in Thoracic and Cardiovascular Surgery. 2021.

Flanders TM, Lang S, Ko TS, Andersen KN, Jahnavi J, Flibotte JJ, Licht DJ, Tasian GE, Stoardi ST, Yodh AG, Lynch JM, Kennedy BC, Storm PB, White BR, Heuer GG, Baker WB. “Optical Detection of Intracranial Pressure with Perfusion Changes in Neonates with Hydrocephalus”. The Journal of Pediatrics. 2021.

2020

Mavroudis CD, Ko TS, Volk LE, Smood B, Morgan RW, Lynch JM, Davarajan M, Boorady TW, Licht DJ, Gaynor JW, Mascio CE, Kilbaugh TJ. “Does supply meet demand? A comparison of perfusion strategies on cerebral metabolism in a neonatal swine model. The Journal of Thoracic and Cardiovascular Surgery. 2020.

Busch DR, Baker WB, Mavroudis CD, Ko TS, Lynch, JM, McCarthy AL, DuPont-Thibodeau G, Buckley EM, Jacobwitz M, Boorady TW, Mensah-Brown K, Connely JT, Yodh AG, Kilbaugh TJ, Licht DJ. “Noninvasive optical measurement of microvascular cerebral hemodynamics and autoregulation in the neonatal ECMO patient“. Pediatric Research. 2020;88:925-933

Ko T, Mavroudis CD, Baker WB, Morano VC, Mensah-Brown K, Boorady TW, Schmidt AL, Lynch JM, Busch DR, Gentile J, Bratinov G, Lin Y, Jeong S, Melchior RW, Rosenthal TM, Shade BC, Schiavo KL, Xiao R, Gaynor JW, Yodh AG, Kilbaugh TJ, Licht DJ. “Non-invasive optical neuromonitoring of the temperature-dependence of cerebral oxygen metabolism during deep hypothermic cardiopulmonary bypass in neonatal swine.” The Journal of Cerebral Blood Flow and Metabolism. 2020;40(1):187-203.

2018

Lynch JM, Ko T, Busch DR, Newland JJ, Winters ME, Mensah-Brown K, Boorady TW, Xiao R, Nicolson SC, Montenegro LM, Gaynor JW, Spray TL, Yodh AG, Naim MY, Licht DJ. “Pre-Operative Cerebral Hemodynamics from Birth to Surgery in Neonates with Critical Congenital Heart Disease.” The Journal of Thoracic and Cardiovascular Surgery. 2018;156(4):1657-1664.

2017

Smith B, Vu E, Kibler K, Rusin CG, Easley RB, Andropolous D, Heinle J, Czosnyka M, Licht DJ, Lynch JM, Brady KM. “Does hypothermia impair cerebrovascular autoregulation in neonates during cardiopulmonary bypass?” Pediatric Anesthesia. 2017;27(9):905-910.

2016

Busch DR, Lynch JM, Winters ME, McCarthy AL, Newland JJ, Ko TK, Cornaglia MA, Radcliffe J, McDonough JM, Samuel J, Matthews E, Xiao R, Yodh AG, Marcus CL, Licht DJ, Tapia IE. “Cerebral Blood Flow Response to Hypercapnia in Children with Obstructive Sleep Apnea Syndrome.” Sleep. 2016;39(1):209-216.

2015

McCarthy AL, Winters ME, Busch DR, Gonzalez-Giraldo E, Ko TS, Lynch JM, Schwab PJ, Xiao R, Buckley EM, Vossough A, Licht DJ. “Scoring system for periventricular leukomalacia in infants with congenital heart disease.” Pediatric Research. 2015;78(3):304-309.

2014

Lynch JM, Buckley EM, Schwab PJ, McCarthy AL, Winters ME, Busch DR, Xiao R, Nicolson SC, Montenegro LM, Fuller S, Gaynor JW, Spray TL, Yodh AG, Naim MY, Licht DJ. “Time to surgery and preoperative cerebral oxygenation predict postoperative ischemic injury in hypoplastic left heart syndrome.” The Journal of Thoracic and Cardiovascular Surgery. 2014;148(5):2181-2188.

Jain V and Buckley EM, Licht DJ, Lynch JM, Schwab PJ, Naim MY, Lavin NA, Nicolson SC, Montenegro LM, Yodh AG, Wehrli FW. “Cerebral Oxygen Metabolism in Neonates with Congenital Heart Disease Quantified by MRI and Optics.” Journal of Cerebral Blood Flow and Metabolism. 2014;34:380-388.

Lynch JM, Buckley EM, Schwab PJ, Busch DR, Hanna BD, Putt ME, Licht DJ, Yodh AG. “Non-invasive optical quantification of cerebral venous oxygen saturation in humans.” Academic Radiology. 2014;21(2):162-167.

2013

Jalali A, Buckley E, Lynch J, Schwab P, Licht D, Natara C. “Prediction of Periventricular Leukomalacia Occurrence in Neonates After Heart Surgery.” IEEE Journal of Biomedical and Health Informatics. 2013;18(4):1453-1460.

Buckley EM, Naim MY, Lynch JM, Goff DA, Diaz LK, Nicolson SC, Montenegro LM, Lavin NA, Durduran T, Spray TL, Gaynor JW, Putt ME, Yodh AG, Fogel MA, Licht DJ. “Sodium Bicarbonate Causes Dose-Dependent Increases in Cerebral Blood Flow in Infants and Children with Single Ventricle Physiology.” Pediatric Research. 2013;73(5):688-673.

2012

Buckley EM, Lynch JM, Goff DA, Schwab PJ, Baker WB, Durduran T, Busch DR, Nicolson SC, Montenegro LM,, Naim MY, Xiao R, Spray TL, Yodh AG, Gaynor JW, Licht DJ. “Early Post-Operative Changes in Cerebral Oxygen Metabolism Following Neonatal Cardiac Surgery: Effects of Surgical Duration.” The Journal of Thoracic and Cardiovascular Surgery. 2012;145(1):196-205.

Buckley EM, Hance D, Pawlowski T, Lynch JM, Wilson FB, Mesquita RC, Durduran T, Diaz LZ, Putt ME, Licht DJ, Fogel MA, and Yodh AG. “Validation of diffuse correlation spectroscopic measurements of cerebral blood flow using phase encoded velocity mapping MRI.” Journal of Biomedical Optics. 2012;17(3):037007.

Lynch JM and Contijoch F, Pokrajac DD, Maidment ADA, Bakic PR. “Shape analysis of simulated breast anatomical structures.” Presented at SPIE Medical Imaging 2012;Physics of Medical Imaging, San Diego, CA. 2012.

2008

Lynch JM, Cianci GC, and Weeks ER. “Dynamics and structure of an aging binary colloidal glass.” Physical Review E, 2008;78:031410.

2004

Lynch JM et al. “Playing with ridiculously expensive black dust: an exploration into the regime of Buckminsterfullerene surface chemistry.” Journal of the PGSS, 2004;23:61-99.

Posters and Presentations

Invited Lectures

2022

Lynch JM. “Monitoring the Vulnerable Period Between Delivery and Surgical Treatment to Improve Neurological Outcomes” – Cardiology 2022: 25th Annual Update on Pediatric and Congenital Cardiovascular Disease, Huntington Beach, CA. Sept. 2, 2022.

Lynch JM. “Diffuse Optics: Shedding Light on Risk for Brain Injury in Congenital Heart Disease” – Texas Children’s Department of Anesthesiology, Perioperative and Pain Medicine PCVA Conference. June 30, 2022.