Alex B. Ruan, MD

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Alex B. Ruan, MD, is a fellow in the Division of Neonatology at Children's Hospital of Philadelphia.

Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - Harvard Medical School, Boston, MA


Pediatrics - Children’s Hospital of Philadelphia, Philadelphia, PA

Titles and Academic Titles


Departments and Services




Isidro RA, Ruan AB, Gannarapu S, et al. Medication‐specific variations in morphological patterns of injury in immune check‐point inhibitor‐associated colitis. Histopathology 2021;78(4):532–41.


Jangi S, Ruan A, Korzenik J, de Silva P. South Asian Patients With Inflammatory Bowel Disease in the United States Demonstrate More Fistulizing and Perianal Crohn Phenotype. Inflammatory Bowel Diseases 2020;26(12):1933–42.

Grover S, Ruan AB, Srivoleti P, et al. Safety of Immune Checkpoint Inhibitors in Patients With Pre-Existing Inflammatory Bowel Disease and Microscopic Colitis. JCO Oncology Practice 2020;16(9):e933–42.

Grover S, Dougan M, Tyan K, Giobbie-Hurder A, Blum S, Ishizuka J, Qazi T, Elias R, Vora K, Ruan AB, Martin-Doyle W, et al. Vitamin D intake is associated with decreased risk of immune checkpoint inhibitor‐induced colitis. Cancer 2020;126(16):3758–67.


Hillis JM*, Ruan AB*, Lazarus JE, Montgomery MW, Berkowitz AL. Clinical Reasoning: A 48-year-old woman with confusion, personality change, and multiple enhancing brain lesions. Neurology 2018;90(19):e1724–9. *Authorship shared equally



Braschi-Amirfarzan M, Ruan A, Srivastava A, et al. Abdominal CT Should not be used to screen for immune checkpoint inhibitor colitis. Gastroenterology 2020;158(6):S-537. Accepted to Digestive Disease Week 2020, cancelled because of COVID-19 pandemic


Ruan A, Braschi Amirfarzan M, Grover S (12/2019). Characteristic Radiographic Patterns of Biopsy-Proven Immune-Related Colitis in Melanoma Patients Treated with Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4) Inhibitors. Accepted to Radiological Society of North America 2019 conference, Chicago, IL.

Jangi S, Ruan A, Desilva P. South Asians in the United States have more aggressive penetrating and perianal Crohn’s Disease. Gastroenterology 2019;156(3):S61–2. Accepted to Digestive Disease Week 2019 and Crohn’s Colitis Foundation Conference 2019

Awards and Honors

2015, Summa Cum Laude, University of Pennsylvania
2015, Neysa Cristol Adams Prize in Biology, Honorable Mention
2014, Phi Beta Kappa

Leadership and Memberships

Memberships in Professional Organizations

2019-present, American Academy of Pediatrics
2015-present, American Medical Association