Patrick M.A. Sleiman, PhD

Papers

2016

de Araújo Lima Leandro, Feio-Dos-Santos Ana Cecília, Belangero Sintia Iole, Gadelha Ary, Bressan Rodrigo Affonseca, Salum Giovanni Abrahão, Pan Pedro Mario, Moriyama Tais Silveira, Graeff-Martins Ana Soledade, Tamanaha Ana Carina, Alvarenga Pedro, Krieger Fernanda Valle, Fleitlich-Bilyk Bacy, Jackowski Andrea Parolin, Brietzke Elisa, Sato João Ricardo, Polanczyk Guilherme Vanoni, Mari Jair de Jesus, Manfro Gisele Gus, do Rosário Maria Conceição, Miguel Eurípedes Constantino, Puga Renato David, Tahira Ana Carolina, Souza Viviane Neri, Chile Thais, Gouveia Gisele Rodrigues, Simões Sérgio Nery, Chang Xiao, Pellegrino Renata, Tian Lifeng, Glessner Joseph T, Hashimoto Ronaldo Fumio, Rohde Luis Augusto, Sleiman Patrick M A, Hakonarson Hakon, Brentani Helena: An integrative approach to investigate the respective roles of single-nucleotide variants and copy-number variants in Attention-Deficit/Hyperactivity Disorder. Scientific reports 6: 22851, 2016.

Netter Petra, Chan Sanny K, Banerjee Pinaki P, Monaco-Shawver Linda, Noroski Lenora M, Hanson Imelda C, Forbes Lisa R, Mace Emily M, Chinen Javier, Gaspar H Bobby, Sleiman Patrick, Hakonarson Hakon, Klein Christoph, Ehlayel Mohammad S, Orange Jordan S: A novel Rab27a mutation binds melanophilin, but not Munc13-4, causing immunodeficiency without albinism. The Journal of allergy and clinical immunology 138(2): 599-601.e3, Aug 2016.

Hysinger Erik B, Roizen Jeffrey D, Mentch Frank D, Vazquez Lyam, Connolly John J, Bradfield Jonathan P, Almoguera Berta, Sleiman Patrick M, Allen Julian L, Levine Michael A, Hakonarson Hakon: Mendelian randomization analysis demonstrates that low vitamin D is unlikely causative for pediatric asthma. The Journal of allergy and clinical immunology Aug 2016.

Chen Rong, Shi Lisong, Hakenberg Jörg, Naughton Brian, Sklar Pamela, Zhang Jianguo, Zhou Hanlin, Tian Lifeng, Prakash Om, Lemire Mathieu, Sleiman Patrick, Cheng Wei-Yi, Chen Wanting, Shah Hardik, Shen Yulan, Fromer Menachem, Omberg Larsson, Deardorff Matthew A, Zackai Elaine, Bobe Jason R, Levin Elissa, Hudson Thomas J, Groop Leif, Wang Jun, Hakonarson Hakon, Wojcicki Anne, Diaz George A, Edelmann Lisa, Schadt Eric E, Friend Stephen H: Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases. Nature biotechnology 34(5): 531-8, May 2016.

Yang Yi, Zhang Lei, Lynch David R, Lukas Thomas, Ahmeti Kreshnik, Sleiman Patrick M A, Ryan Eanna, Schadt Kimberly A, Newman Jordan H, Deng Han-Xiang, Siddique Nailah, Siddique Teepu: Compound heterozygote mutations in SPG7 in a family with adult-onset primary lateral sclerosis. Neurology. Genetics 2(2): e60, Apr 2016.

Gadelha Ary, Coleman Jonathan, Breen Gerome, Mazzoti Diego Robles, Yonamine Camila M, Pellegrino Renata, Ota Vanessa Kiyomi, Belangero Sintia Iole, Glessner Joseph, Sleiman Patrick, Hakonarson Hakon, Hayashi Mirian A F, Bressan Rodrigo A: Genome-wide investigation of schizophrenia associated plasma Ndel1 enzyme activity. Schizophrenia research S0920-9964(16): 30043-3, Feb 2016.

2015

Paternoster Lavinia, Standl Marie, Waage Johannes, Baurecht Hansjörg, Hotze Melanie, Strachan David P, Curtin John A, Bønnelykke Klaus, Tian Chao, Takahashi Atsushi, Esparza-Gordillo Jorge, Alves Alexessander Couto, Thyssen Jacob P, den Dekker Herman T, Ferreira Manuel A, Altmaier Elisabeth, Sleiman Patrick M A, Xiao Feng Li, Gonzalez Juan R, Marenholz Ingo, Kalb Birgit, Pino-Yanes Maria, Xu Cheng-Jian, Carstensen Lisbeth, Groen-Blokhuis Maria M, Venturini Cristina, Pennell Craig E, Barton Sheila J, Levin Albert M, Curjuric Ivan, Bustamante Mariona, Kreiner-Møller Eskil, Lockett Gabrielle A, Bacelis Jonas, Bunyavanich Supinda, Myers Rachel A, Matanovic Anja, Kumar Ashish, Tung Joyce Y, Hirota Tomomitsu, Kubo Michiaki, McArdle Wendy L, Henderson A John, Kemp John P, Zheng Jie, Smith George Davey, Rüschendorf Franz, Bauerfeind Anja, Lee-Kirsch Min Ae, Arnold Andreas, Homuth Georg, Schmidt Carsten O, Mangold Elisabeth, Cichon Sven, Keil Thomas, Rodríguez Elke, Peters Annette, Franke Andre, Lieb Wolfgang, Novak Natalija, Fölster-Holst Regina, Horikoshi Momoko, Pekkanen Juha, Sebert Sylvain, Husemoen Lise L, Grarup Niels, de Jongste Johan C, Rivadeneira Fernando, Hofman Albert, Jaddoe Vincent W V, Pasmans Suzanne G M A, Elbert Niels J, Uitterlinden André G, Marks Guy B, Thompson Philip J, Matheson Melanie C, Robertson Colin F, Ried Janina S, Li Jin, Zuo Xian Bo, Zheng Xiao Dong, Yin Xian Yong, Sun Liang Dan, McAleer Maeve A, O'Regan Grainne M, Fahy Caoimhe M R, Campbell Linda E, Macek Milan, Kurek Michael, Hu Donglei, Eng Celeste, Postma Dirkje S, Feenstra Bjarke, Geller Frank, Hottenga Jouke Jan, Middeldorp Christel M, Hysi Pirro, Bataille Veronique, Spector Tim, Tiesler Carla M T, Thiering Elisabeth, Padhukasahasram Badri, Yang James J, Imboden Medea, Huntsman Scott, Vilor-Tejedor Natàlia, Relton Caroline L, Myhre Ronny, Nystad Wenche, Custovic Adnan, Weiss Scott T, Meyers Deborah A, Söderhäll Cilla, Melén Erik, Ober Carole, Raby Benjamin A, Simpson Angela, Jacobsson Bo, Holloway John W, Bisgaard Hans, Sunyer Jordi, Probst-Hensch Nicole M, Williams L Keoki, Godfrey Keith M, Wang Carol A, Boomsma Dorret I, Melbye Mads, Koppelman Gerard H, Jarvis Deborah, McLean W H Irwin, Irvine Alan D, Zhang Xue Jun, Hakonarson Hakon, Gieger Christian, Burchard Esteban G, Martin Nicholas G, Duijts Liesbeth, Linneberg Allan, Jarvelin Marjo-Riitta, Nöthen Markus M, Lau Susanne, Hübner Norbert, Lee Young-Ae, Tamari Mayumi, Hinds David A, Glass Daniel, Brown Sara J, Heinrich Joachim, Evans David M, Weidinger Stephan: Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nature genetics 47(12): 1449-56, Dec 2015.

Marenholz Ingo, Esparza-Gordillo Jorge, Rüschendorf Franz, Bauerfeind Anja, Strachan David P, Spycher Ben D, Baurecht Hansjörg, Margaritte-Jeannin Patricia, Sääf Annika, Kerkhof Marjan, Ege Markus, Baltic Svetlana, Matheson Melanie C, Li Jin, Michel Sven, Ang Wei Q, McArdle Wendy, Arnold Andreas, Homuth Georg, Demenais Florence, Bouzigon Emmanuelle, Söderhäll Cilla, Pershagen Göran, de Jongste Johan C, Postma Dirkje S, Braun-Fahrländer Charlotte, Horak Elisabeth, Ogorodova Ludmila M, Puzyrev Valery P, Bragina Elena Yu, Hudson Thomas J, Morin Charles, Duffy David L, Marks Guy B, Robertson Colin F, Montgomery Grant W, Musk Bill, Thompson Philip J, Martin Nicholas G, James Alan, Sleiman Patrick, Toskala Elina, Rodriguez Elke, Fölster-Holst Regina, Franke Andre, Lieb Wolfgang, Gieger Christian, Heinzmann Andrea, Rietschel Ernst, Keil Thomas, Cichon Sven, Nöthen Markus M, Pennell Craig E, Sly Peter D, Schmidt Carsten O, Matanovic Anja, Schneider Valentin, Heinig Matthias, Hübner Norbert, Holt Patrick G, Lau Susanne, Kabesch Michael, Weidinger Stefan, Hakonarson Hakon, Ferreira Manuel A R, Laprise Catherine, Freidin Maxim B, Genuneit Jon, Koppelman Gerard H, Melén Erik, Dizier Marie-Hélène, Henderson A John, Lee Young Ae: Meta-analysis identifies seven susceptibility loci involved in the atopic march. Nature communications 6: 8804, 2015.

Li Yun R, Zhao Sihai D, Li Jin, Bradfield Jonathan P, Mohebnasab Maede, Steel Laura, Kobie Julie, Abrams Debra J, Mentch Frank D, Glessner Joseph T, Guo Yiran, Wei Zhi, Connolly John J, Cardinale Christopher J, Bakay Marina, Li Dong, Maggadottir S Melkorka, Thomas Kelly A, Qui Haijun, Chiavacci Rosetta M, Kim Cecilia E, Wang Fengxiang, Snyder James, Flatø Berit, Førre Øystein, Denson Lee A, Thompson Susan D, Becker Mara L, Guthery Stephen L, Latiano Anna, Perez Elena, Resnick Elena, Strisciuglio Caterina, Staiano Annamaria, Miele Erasmo, Silverberg Mark S, Lie Benedicte A, Punaro Marilynn, Russell Richard K, Wilson David C, Dubinsky Marla C, Monos Dimitri S, Annese Vito, Munro Jane E, Wise Carol, Chapel Helen, Cunningham-Rundles Charlotte, Orange Jordan S, Behrens Edward M, Sullivan Kathleen E, Kugathasan Subra, Griffiths Anne M, Satsangi Jack, Grant Struan F A, Sleiman Patrick M A, Finkel Terri H, Polychronakos Constantin, Baldassano Robert N, Luning Prak Eline T, Ellis Justine A, Li Hongzhe, Keating Brendan J, Hakonarson Hakon: Genetic sharing and heritability of paediatric age of onset autoimmune diseases. Nature communications 9(6): 8442, 2015.

Chang Xiao, Li Jin, Guo Yiran, Wei Zhi, Mentch Frank D, Hou Cuiping, Zhao Yan, Qiu Haijun, Kim Cecilia, Sleiman Patrick M A, Hakonarson Hakon: Genome-wide association study of serum minerals levels in children of different ethnic background. PloS one 10(4): e0123499, 2015.

Chang Xiao, Glessner Joseph, Tin Adrienne, Li Jin, Guo Yiran, Wei Zhi, Liu Yichuan, Mentch Frank D, Hou Cuiping, Zhao Yan, Wang Tiancheng, Qiu Haijun, Kim Cecilia, Sleiman Patrick M A, Hakonarson Hakon: Genome-wide association study reveals two loci for serum magnesium concentrations in European-American children. Scientific reports 5: 18792, 2015.

Banerjee A, Wang H-Y, Borgmann-Winter K E, MacDonald M L, Kaprielian H, Stucky A, Kvasic J, Egbujo C, Ray R, Talbot K, Hemby S E, Siegel S J, Arnold S E, Sleiman P, Chang X, Hakonarson H, Gur R E, Hahn C-G: Src kinase as a mediator of convergent molecular abnormalities leading to NMDAR hypoactivity in schizophrenia. Molecular psychiatry 20(9): 1091-100, Sep 2015.

Li Yun R, Li Jin, Zhao Sihai D, Bradfield Jonathan P, Mentch Frank D, Maggadottir S Melkorka, Hou Cuiping, Abrams Debra J, Chang Diana, Gao Feng, Guo Yiran, Wei Zhi, Connolly John J, Cardinale Christopher J, Bakay Marina, Glessner Joseph T, Li Dong, Kao Charlly, Thomas Kelly A, Qiu Haijun, Chiavacci Rosetta M, Kim Cecilia E, Wang Fengxiang, Snyder James, Richie Marylyn D, Flatø Berit, Førre Øystein, Denson Lee A, Thompson Susan D, Becker Mara L, Guthery Stephen L, Latiano Anna, Perez Elena, Resnick Elena, Russell Richard K, Wilson David C, Silverberg Mark S, Annese Vito, Lie Benedicte A, Punaro Marilynn, Dubinsky Marla C, Monos Dimitri S, Strisciuglio Caterina, Staiano Annamaria, Miele Erasmo, Kugathasan Subra, Ellis Justine A, Munro Jane E, Sullivan Kathleen E, Wise Carol A, Chapel Helen, Cunningham-Rundles Charlotte, Grant Struan F A, Orange Jordan S, Sleiman Patrick M A, Behrens Edward M, Griffiths Anne M, Satsangi Jack, Finkel Terri H, Keinan Alon, Prak Eline T Luning, Polychronakos Constantin, Baldassano Robert N, Li Hongzhe, Keating Brendan J, Hakonarson Hakon: Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. Nature medicine 21(9): 1018-27, Aug 2015.

Li Jin, Fung Irene, Glessner Joseph T, Pandey Rahul, Wei Zhi, Bakay Marina, Mentch Frank D, Pellegrino Renata, Wang Tiancheng, Kim Cecilia, Hou Cuiping, Wang Fengxiang, Chiavacci Rosetta M, Thomas Kelly A, Spergel Jonathan M, Hakonarson Hakon, Sleiman Patrick M A: Copy Number Variations in CTNNA3 and RBFOX1 Associate with Pediatric Food Allergy. Journal of immunology (Baltimore, Md. : 1950) 195(4): 1599-607, Aug 2015.

Brehm John M, Ramratnam Sima K, Tse Sze Man, Croteau-Chonka Damien C, Pino-Yanes Maria, Rosas-Salazar Christian, Litonjua Augusto A, Raby Benjamin A, Boutaoui Nadia, Han Yueh-Ying, Chen Wei, Forno Erick, Marsland Anna L, Nugent Nicole R, Eng Celeste, Colón-Semidey Angel, Alvarez María, Acosta-Pérez Edna, Spear Melissa L, Martinez Fernando D, Avila Lydiana, Weiss Scott T, Soto-Quiros Manuel, Ober Carole, Nicolae Dan L, Barnes Kathleen C, Lemanske Robert F, Strunk Robert C, Liu Andrew, London Stephanie J, Gilliland Frank, Sleiman Patrick, March Michael, Hakonarson Hakon, Duan Qing Ling, Kolls Jay K, Fritz Gregory K, Hu Donglei, Fani Negar, Stevens Jennifer S, Almli Lynn M, Burchard Esteban G, Shin Jaemin, McQuaid Elizabeth L, Ressler Kerry, Canino Glorisa, Celedón Juan C: Stress and Bronchodilator Response in Children with Asthma. American journal of respiratory and critical care medicine 192(1): 47-56, Jul 2015.

Robinson E B, Kirby A, Ruparel K, Yang J, McGrath L, Anttila V, Neale B M, Merikangas K, Lehner T, Sleiman P M A, Daly M J, Gur R, Gur R, Hakonarson H: The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort. Molecular psychiatry 20(4): 454-8, Apr 2015.

Lill Christina M, Rengmark Aina, Pihlstrøm Lasse, Fogh Isabella, Shatunov Aleksey, Sleiman Patrick M, Wang Li-San, Liu Tian, Lassen Christina F, Meissner Esther, Alexopoulos Panos, Calvo Andrea, Chio Adriano, Dizdar Nil, Faltraco Frank, Forsgren Lars, Kirchheiner Julia, Kurz Alexander, Larsen Jan P, Liebsch Maria, Linder Jan, Morrison Karen E, Nissbrandt Hans, Otto Markus, Pahnke Jens, Partch Amanda, Restagno Gabriella, Rujescu Dan, Schnack Cathrin, Shaw Christopher E, Shaw Pamela J, Tumani Hayrettin, Tysnes Ole-Bjørn, Valladares Otto, Silani Vincenzo, van den Berg Leonard H, van Rheenen Wouter, Veldink Jan H, Lindenberger Ulman, Steinhagen-Thiessen Elisabeth, Teipel Stefan, Perneczky Robert, Hakonarson Hakon, Hampel Harald, von Arnim Christine A F, Olsen Jørgen H, Van Deerlin Vivianna M, Al-Chalabi Ammar, Toft Mathias, Ritz Beate, Bertram Lars: The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association 15: 252-9, Apr 2015.

Calkins Monica E, Merikangas Kathleen R, Moore Tyler M, Burstein Marcy, Behr Meckenzie A, Satterthwaite Theodore D, Ruparel Kosha, Wolf Daniel H, Roalf David R, Mentch Frank D, Qiu Haijun, Chiavacci Rosetta, Connolly John J, Sleiman Patrick M A, Gur Ruben C, Hakonarson Hakon, Gur Raquel E: The Philadelphia Neurodevelopmental Cohort: constructing a deep phenotyping collaborative. Journal of child psychology and psychiatry, and allied disciplines  Dec;56(12): 1356-69, Apr 2015.

Satterthwaite Theodore D, Connolly John J, Ruparel Kosha, Calkins Monica E, Jackson Chad, Elliott Mark A, Roalf David R, Ryan Hopsona Karthik Prabhakaran, Behr Meckenzie, Qiu Haijun, Mentch Frank D, Chiavacci Rosetta, Sleiman Patrick M A, Gur Ruben C, Hakonarson Hakon, Gur Raquel E: The Philadelphia Neurodevelopmental Cohort: A publicly available resource for the study of normal and abnormal brain development in youth. NeuroImage 15: 252-9, Mar 2015.

2014

Sleiman Patrick, Bradfield Jonathan, Mentch Frank, Almoguera Berta, Connolly John, Hakonarson Hakon: Assessing the functional consequence of loss of function variants using electronic medical record and large-scale genomics consortium efforts. Frontiers in genetics 5: 105, 2014.

Sleiman Patrick M A, Wang Mei-Lun, Cianferoni Antonella, Aceves Seema, Gonsalves Nirmala, Nadeau Kari, Bredenoord Albert J, Furuta Glenn T, Spergel Jonathan M, Hakonarson Hakon: GWAS identifies four novel eosinophilic esophagitis loci. Nature communications 5: 5593, 2014.

Almoguera Berta, Vazquez Lyam, Connolly John J, Bradfield Jonathan, Sleiman Patrick, Keating Brendan, Hakonarson Hakon: Imputation of TPMT defective alleles for the identification of patients with high-risk phenotypes. Frontiers in genetics 5: 96, 2014.

Calkins Monica E, Moore Tyler M, Merikangas Kathleen R, Burstein Marcy, Satterthwaite Theodore D, Bilker Warren B, Ruparel Kosha, Chiavacci Rosetta, Wolf Daniel H, Mentch Frank, Qiu Haijun, Connolly John J, Sleiman Patrick A, Hakonarson Hakon, Gur Ruben C, Gur Raquel E: The psychosis spectrum in a young U.S. community sample: findings from the Philadelphia Neurodevelopmental Cohort. World psychiatry : official journal of the World Psychiatric Association (WPA) 13(3): 296-305, Oct 2014.

van der Valk Ralf J P, Duijts Liesbeth, Timpson Nicolas J, Salam Muhammad T, Standl Marie, Curtin John A, Genuneit Jon, Kerhof Marjan, Kreiner-Møller Eskil, Cáceres Alejandro, Gref Anna, Liang Liming L, Taal H Rob, Bouzigon Emmanuelle, Demenais Florence, Nadif Rachel, Ober Carole, Thompson Emma E, Estrada Karol, Hofman Albert, Uitterlinden André G, van Duijn Cornélia, Rivadeneira Fernando, Li Xia, Eckel Sandrah P, Berhane Kiros, Gauderman W James, Granell Raquel, Evans David M, St Pourcain Beate, McArdle Wendy, Kemp John P, Smith George Davey, Tiesler Carla M T, Flexeder Claudia, Simpson Angela, Murray Clare S, Fuchs Oliver, Postma Dirkje S, Bønnelykke Klaus, Torrent Maties, Andersson Martin, Sleiman Patrick, Hakonarson Hakon, Cookson William O, Moffatt Miriam F, Paternoster Lavinia, Melén Erik, Sunyer Jordi, Bisgaard Hans, Koppelman Gerard H, Ege Markus, Custovic Adnan, Heinrich Joachim, Gilliland Frank D, Henderson Alexander J, Jaddoe Vincent W V, de Jongste Johan C: Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants. The Journal of allergy and clinical immunology 134(1): 46-55, Jul 2014.

Bønnelykke Klaus, Sleiman Patrick, Nielsen Kasper, Kreiner-Møller Eskil, Mercader Josep M, Belgrave Danielle, den Dekker Herman T, Husby Anders, Sevelsted Astrid, Faura-Tellez Grissel, Mortensen Li Juel, Paternoster Lavinia, Flaaten Richard, Mølgaard Anne, Smart David E, Thomsen Philip F, Rasmussen Morten A, Bonàs-Guarch Silvia, Holst Claus, Nohr Ellen A, Yadav Rachita, March Michael E, Blicher Thomas, Lackie Peter M, Jaddoe Vincent W V, Simpson Angela, Holloway John W, Duijts Liesbeth, Custovic Adnan, Davies Donna E, Torrents David, Gupta Ramneek, Hollegaard Mads V, Hougaard David M, Hakonarson Hakon, Bisgaard Hans: A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations. Nature genetics 46(1): 51-5, Jan 2014.

2013

Sleiman Patrick, Wang Dai, Glessner Joseph, Hadley Dexter, Gur Raquel E, Cohen Nadine, Li Qingqin, Hakonarson Hakon: GWAS meta analysis identifies TSNARE1 as a novel Schizophrenia / Bipolar susceptibility locus. Scientific reports 3: 3075, 2013.

Siracusa Mark C, Saenz Steven A, Wojno Elia D Tait, Kim Brian S, Osborne Lisa C, Ziegler Carly G, Benitez Alain J, Ruymann Kathryn R, Farber Donna L, Sleiman Patrick M, Hakonarson Hakon, Cianferoni Antonella, Wang Mei-Lun, Spergel Jonathan M, Comeau Michael R, Artis David: Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation. Immunity 39(6): 1158-70, Dec 2013.

Ong Bruce A, Li Jin, McDonough Joseph M, Wei Zhi, Kim Cecilia, Chiavacci Rosetta, Mentch Frank, Caboot Jason B, Spergel Jonathan, Allen Julian L, Sleiman Patrick M A, Hakonarson Hakon: Gene network analysis in a pediatric cohort identifies novel lung function genes. PloS one 8(9): e72899, 2013.

Mechelli R, Umeton R, Policano C, Annibali V, Coarelli G, Ricigliano VA, Vittori D, Fornasiero A, Buscarinu MC; International Multiple Sclerosis Genetics Consortium; Wellcome Trust Case Control Consortium,2, Romano S, Salvetti M, Ristori G.: A "candidate-interactome" aggregate analysis of genome-wide association data in multiple sclerosis. PLoS One 16;8(5): e63300, 2013.

Glessner Joseph T, Smith Albert Vernon, Panossian Saarene, Kim Cecilia E, Takahashi Nagahide, Thomas Kelly A, Wang Fengxiang, Seidler Kallyn, Harris Tamara B, Launer Lenore J, Keating Brendan, Connolly John, Sleiman Patrick M A, Buxbaum Joseph D, Grant Struan F A, Gudnason Vilmundur, Hakonarson Hakon: Copy number variations in alternative splicing gene networks impact lifespan. PloS one 8(1): e53846, 2013.

Kreiner-Møller E, Chawes B L K, Vissing N H, Koppelman G H, Postma D S, Madsen J S, Olsen D A, Baty F, Vonk J M, Kerkhof M, Sleiman P, Hakonarsson H, Mortensen L J, Poorisrisak P, Bisgaard H, Bønnelykke K: VEGFA variants are associated with pre-school lung function, but not neonatal lung function. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 43(11): 1236-45, Nov 2013.

Satterthwaite Theodore D, Elliott Mark A, Ruparel Kosha, Loughead James, Prabhakaran Karthik, Calkins Monica E, Hopson Ryan, Jackson Chad, Keefe Jack, Riley Marisa, Mensh Frank D, Sleiman Patrick, Verma Ragini, Davatzikos Christos, Hakonarson Hakon, Gur Ruben C, Gur Raquel E: Neuroimaging of the Philadelphia Neurodevelopmental Cohort. NeuroImage 86: 544-53, Aug 2013.

Noti Mario, Wojno Elia D Tait, Kim Brian S, Siracusa Mark C, Giacomin Paul R, Nair Meera G, Benitez Alain J, Ruymann Kathryn R, Muir Amanda B, Hill David A, Chikwava Kudakwashe R, Moghaddam Amin E, Sattentau Quentin J, Alex Aneesh, Zhou Chao, Yearley Jennifer H, Menard-Katcher Paul, Kubo Masato, Obata-Ninomiya Kazushige, Karasuyama Hajime, Comeau Michael R, Brown-Whitehorn Terri, de Waal Malefyt Rene, Sleiman Patrick M, Hakonarson Hakon, Cianferoni Antonella, Falk Gary W, Wang Mei-Lun, Spergel Jonathan M, Artis David: Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis. Nature medicine 19(8): 1005-13, Aug 2013.

Bønnelykke Klaus, Matheson Melanie C, Pers Tune H, Granell Raquel, Strachan David P, Alves Alexessander Couto, Linneberg Allan, Curtin John A, Warrington Nicole M, Standl Marie, Kerkhof Marjan, Jonsdottir Ingileif, Bukvic Blazenka K, Kaakinen Marika, Sleimann Patrick, Thorleifsson Gudmar, Thorsteinsdottir Unnur, Schramm Katharina, Baltic Svetlana, Kreiner-Møller Eskil, Simpson Angela, Pourcain Beate St, Coin Lachlan, Hui Jennie, Walters Eugene H, Tiesler Carla M T, Duffy David L, Jones Graham, Ring Susan M, McArdle Wendy L, Price Loren, Robertson Colin F, Pekkanen Juha, Tang Clara S, Thiering Elisabeth, Montgomery Grant W, Hartikainen Anna-Liisa, Dharmage Shyamali C, Husemoen Lise L, Herder Christian, Kemp John P, Elliot Paul, James Alan, Waldenberger Melanie, Abramson Michael J, Fairfax Benjamin P, Knight Julian C, Gupta Ramneek, Thompson Philip J, Holt Patrick, Sly Peter, Hirschhorn Joel N, Blekic Mario, Weidinger Stephan, Hakonarsson Hakon, Stefansson Kari, Heinrich Joachim, Postma Dirkje S, Custovic Adnan, Pennell Craig E, Jarvelin Marjo-Riitta, Koppelman Gerard H, Timpson Nicholas, Ferreira Manuel A, Bisgaard Hans, Henderson A John: Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization. Nature genetics 45(8): 902-6, Aug 2013.

Al Daama Saad A, Housawi Yousef H, Dridi Walid, Sager Mohammed, Otieno F George, Hou Cuiping, Vasquez Lyam, Kim Cecilia, Tian Lifeng, Sleiman Patrick, Hakonarson Hakon: A missense mutation in ANKRD26 segregates with thrombocytopenia. Blood 122(3): 461-2, Jul 2013.

Chen Zhao, Tang Hua, Qayyum Rehan, Schick Ursula M, Nalls Michael A, Handsaker Robert, Li Jin, Lu Yingchang, Yanek Lisa R, Keating Brendan, Meng Yan, van Rooij Frank J A, Okada Yukinori, Kubo Michiaki, Rasmussen-Torvik Laura, Keller Margaux F, Lange Leslie, Evans Michele, Bottinger Erwin P, Linderman Michael D, Ruderfer Douglas M, Hakonarson Hakon, Papanicolaou George, Zonderman Alan B, Gottesman Omri, Thomson Cynthia, Ziv Elad, Singleton Andrew B, Loos Ruth J F, Sleiman Patrick M A, Ganesh Santhi, McCarroll Steven, Becker Diane M, Wilson James G, Lettre Guillaume, Reiner Alexander P: Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network. Human molecular genetics 22(12): 2529-38, Jun 2013.

Martignetti John A, Tian Lifeng, Li Dong, Ramirez Maria Celeste M, Camacho-Vanegas Olga, Camacho Sandra Catalina, Guo Yiran, Zand Dina J, Bernstein Audrey M, Masur Sandra K, Kim Cecilia E, Otieno Frederick G, Hou Cuiping, Abdel-Magid Nada, Tweddale Ben, Metry Denise, Fournet Jean-Christophe, Papp Eniko, McPherson Elizabeth W, Zabel Carrie, Vaksmann Guy, Morisot Cyril, Keating Brendan, Sleiman Patrick M, Cleveland Jeffrey A, Everman David B, Zackai Elaine, Hakonarson Hakon: Mutations in PDGFRB Cause Autosomal-Dominant Infantile Myofibromatosis. American journal of human genetics 92(6): 1001-7, May 2013.

Li Jin, Glessner Joseph T, Zhang Haitao, Hou Cuiping, Wei Zhi, Bradfield Jonathan P, Mentch Frank D, Guo Yiran, Kim Cecilia, Xia Qianghua, Chiavacci Rosetta M, Thomas Kelly A, Qiu Haijun, Grant Struan F A, Furth Susan L, Hakonarson Hakon, Sleiman Patrick M A: GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. Human molecular genetics 22(7): 1457-64, Apr 2013.

Deliard Sandra, Panossian Saarene, Mentch Frank D, Kim Cecilia E, Hou Cuiping, Frackelton Edward C, Bradfield Jonathan P, Glessner Joseph T, Zhang Haitao, Wang Kai, Sleiman Patrick M A, Chiavacci Rosetta M, Berkowitz Robert I, Hakonarson Hakon, Zhao Jianhua, Grant Struan F A: The missense variation landscape of FTO, MC4R, and TMEM18 in obese children of African Ancestry. Obesity (Silver Spring, Md.) 21(1): 159-63, Jan 2013.

2012

Lasky-Su J, Himes B E, Raby B A, Klanderman B J, Sylvia J Senter, Lange C, Melen E, Martinez F D, Israel E, Gauderman J, Gilliland F, Sleiman P, Hakonarson H, Celedón J C, Soto-Quiros M, Avila L, Lima J J, Irvin C G, Peters S P, Boushey H, Chinchilli V M, Mauger D, Tantisira K, Weiss S T: HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 42(12): 1724-33, Dec 2012.

Bradfield Jonathan P, Taal H Rob, Timpson Nicholas J, Scherag André, Lecoeur Cecile, Warrington Nicole M, Hypponen Elina, Holst Claus, Valcarcel Beatriz, Thiering Elisabeth, Salem Rany M, Schumacher Fredrick R, Cousminer Diana L, Sleiman Patrick M A, Zhao Jianhua, Berkowitz Robert I, Vimaleswaran Karani S, Jarick Ivonne, Pennell Craig E, Evans David M, St Pourcain Beate, Berry Diane J, Mook-Kanamori Dennis O, Hofman Albert, Rivadeneira Fernando, Uitterlinden André G, van Duijn Cornelia M, van der Valk Ralf J P, de Jongste Johan C, Postma Dirkje S, Boomsma Dorret I, Gauderman W James, Hassanein Mohamed T, Lindgren Cecilia M, Mägi Reedik, Boreham Colin A G, Neville Charlotte E, Moreno Luis A, Elliott Paul, Pouta Anneli, Hartikainen Anna-Liisa, Li Mingyao, Raitakari Olli, Lehtimäki Terho, Eriksson Johan G, Palotie Aarno, Dallongeville Jean, Das Shikta, Deloukas Panos, McMahon George, Ring Susan M, Kemp John P, Buxton Jessica L, Blakemore Alexandra I F, Bustamante Mariona, Guxens Mònica, Hirschhorn Joel N, Gillman Matthew W, Kreiner-Møller Eskil, Bisgaard Hans, Gilliland Frank D, Heinrich Joachim, Wheeler Eleanor, Barroso Inês, O'Rahilly Stephen, Meirhaeghe Aline, Sørensen Thorkild I A, Power Chris, Palmer Lyle J, Hinney Anke, Widen Elisabeth, Farooqi I Sadaf, McCarthy Mark I, Froguel Philippe, Meyre David, Hebebrand Johannes, Jarvelin Marjo-Riitta, Jaddoe Vincent W V, Smith George Davey, Hakonarson Hakon, Grant Struan F A: A genome-wide association meta-analysis identifies new childhood obesity loci. Nature genetics 44(5): 526-31, 2012.

Gur Ruben C, Richard Jan, Calkins Monica E, Chiavacci Rosetta, Hansen John A, Bilker Warren B, Loughead James, Connolly John J, Qiu Haijun, Mentch Frank D, Abou-Sleiman Patrick M, Hakonarson Hakon, Gur Raquel E: Age group and sex differences in performance on a computerized neurocognitive battery in children age 8-21. Neuropsychology 26(2): 251-65, Mar 2012.

Paternoster Lavinia, Standl Marie, Chen Chih-Mei, Ramasamy Adaikalavan, Bønnelykke Klaus, Duijts Liesbeth, Ferreira Manuel A, Alves Alexessander Couto, Thyssen Jacob P, Albrecht Eva, Baurecht Hansjörg, Feenstra Bjarke, Sleiman Patrick M A, Hysi Pirro, Warrington Nicole M, Curjuric Ivan, Myhre Ronny, Curtin John A, Groen-Blokhuis Maria M, Kerkhof Marjan, Sääf Annika, Franke Andre, Ellinghaus David, Fölster-Holst Regina, Dermitzakis Emmanouil, Montgomery Stephen B, Prokisch Holger, Heim Katharina, Hartikainen Anna-Liisa, Pouta Anneli, Pekkanen Juha, Blakemore Alexandra I F, Buxton Jessica L, Kaakinen Marika, Duffy David L, Madden Pamela A, Heath Andrew C, Montgomery Grant W, Thompson Philip J, Matheson Melanie C, Le Souëf Peter, St Pourcain Beate, Smith George Davey, Henderson John, Kemp John P, Timpson Nicholas J, Deloukas Panos, Ring Susan M, Wichmann H-Erich, Müller-Nurasyid Martina, Novak Natalija, Klopp Norman, Rodríguez Elke, McArdle Wendy, Linneberg Allan, Menné Torkil, Nohr Ellen A, Hofman Albert, Uitterlinden André G, van Duijn Cornélia M, Rivadeneira Fernando, de Jongste Johan C, van der Valk Ralf J P, Wjst Matthias, Jogi Rain, Geller Frank, Boyd Heather A, Murray Jeffrey C, Kim Cecilia, Mentch Frank, March Michael, Mangino Massimo, Spector Tim D, Bataille Veronique, Pennell Craig E, Holt Patrick G, Sly Peter, Tiesler Carla M T, Thiering Elisabeth, Illig Thomas, Imboden Medea, Nystad Wenche, Simpson Angela, Hottenga Jouke-Jan, Postma Dirkje, Koppelman Gerard H, Smit Henriette A, Söderhäll Cilla, Chawes Bo, Kreiner-Møller Eskil, Bisgaard Hans, Melén Erik, Boomsma Dorret I, Custovic Adnan, Jacobsson Bo, Probst-Hensch Nicole M, Palmer Lyle J, Glass Daniel, Hakonarson Hakon, Melbye Mads, Jarvis Deborah L, Jaddoe Vincent W V, Gieger Christian, Strachan David P, Martin Nicholas G, Jarvelin Marjo-Riitta, Heinrich Joachim, Evans David M, Weidinger Stephan: Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Nature genetics 44(2): 187-92, Feb 2012.

Elia Josephine, Glessner Joseph T, Wang Kai, Takahashi Nagahide, Shtir Corina J, Hadley Dexter, Sleiman Patrick M A, Zhang Haitao, Kim Cecilia E, Robison Reid, Lyon Gholson J, Flory James H, Bradfield Jonathan P, Imielinski Marcin, Hou Cuiping, Frackelton Edward C, Chiavacci Rosetta M, Sakurai Takeshi, Rabin Cara, Middleton Frank A, Thomas Kelly A, Garris Maria, Mentch Frank, Freitag Christine M, Steinhausen Hans-Christoph, Todorov Alexandre A, Reif Andreas, Rothenberger Aribert, Franke Barbara, Mick Eric O, Roeyers Herbert, Buitelaar Jan, Lesch Klaus-Peter, Banaschewski Tobias, Ebstein Richard P, Mulas Fernando, Oades Robert D, Sergeant Joseph, Sonuga-Barke Edmund, Renner Tobias J, Romanos Marcel, Romanos Jasmin, Warnke Andreas, Walitza Susanne, Meyer Jobst, Pálmason Haukur, Seitz Christiane, Loo Sandra K, Smalley Susan L, Biederman Joseph, Kent Lindsey, Asherson Philip, Anney Richard J L, Gaynor J William, Shaw Philip, Devoto Marcella, White Peter S, Grant Struan F A, Buxbaum Joseph D, Rapoport Judith L, Williams Nigel M, Nelson Stanley F, Faraone Stephen V, Hakonarson Hakon: Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder. Nature genetics 44(1): 78-84, Jan 2012.

2011

Zhao Jianhua, Bradfield Jonathan P, Zhang Haitao, Sleiman Patrick M, Kim Cecilia E, Glessner Joseph T, Deliard Sandra, Thomas Kelly A, Frackelton Edward C, Li Mingyao, Chiavacci Rosetta M, Berkowitz Robert I, Hakonarson Hakon, Grant Struan F A: Role of BMI-associated loci identified in GWAS meta-analyses in the context of common childhood obesity in European Americans. Obesity (Silver Spring, Md.) 19(12): 2436-9, Dec 2011.

Bradfield Jonathan P, Qu Hui-Qi, Wang Kai, Zhang Haitao, Sleiman Patrick M, Kim Cecilia E, Mentch Frank D, Qiu Haijun, Glessner Joseph T, Thomas Kelly A, Frackelton Edward C, Chiavacci Rosetta M, Imielinski Marcin, Monos Dimitri S, Pandey Rahul, Bakay Marina, Grant Struan F A, Polychronakos Constantin, Hakonarson Hakon: A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci. PLoS genetics 7(9): e1002293, Sep 2011.

Sawcer Stephen, Hellenthal Garrett, Pirinen Matti, Spencer Chris C A, Patsopoulos Nikolaos A, Moutsianas Loukas, Dilthey Alexander, Su Zhan, Freeman Colin, Hunt Sarah E, Edkins Sarah, Gray Emma, Booth David R, Potter Simon C, Goris An, Band Gavin, Oturai Annette Bang, Strange Amy, Saarela Janna, Bellenguez Céline, Fontaine Bertrand, Gillman Matthew, Hemmer Bernhard, Gwilliam Rhian, Zipp Frauke, Jayakumar Alagurevathi, Martin Roland, Leslie Stephen, Hawkins Stanley, Giannoulatou Eleni, D'Alfonso Sandra, Blackburn Hannah, Martinelli Boneschi Filippo, Liddle Jennifer, Harbo Hanne F, Perez Marc L, Spurkland Anne, Waller Matthew J, Mycko Marcin P, Ricketts Michelle, Comabella Manuel, Hammond Naomi, Kockum Ingrid, McCann Owen T, Ban Maria, Whittaker Pamela, Kemppinen Anu, Weston Paul, Hawkins Clive, Widaa Sara, Zajicek John, Dronov Serge, Robertson Neil, Bumpstead Suzannah J, Barcellos Lisa F, Ravindrarajah Rathi, Abraham Roby, Alfredsson Lars, Ardlie Kristin, Aubin Cristin, Baker Amie, Baker Katharine, Baranzini Sergio E, Bergamaschi Laura, Bergamaschi Roberto, Bernstein Allan, Berthele Achim, Boggild Mike, Bradfield Jonathan P, Brassat David, Broadley Simon A, Buck Dorothea, Butzkueven Helmut, Capra Ruggero, Carroll William M, Cavalla Paola, Celius Elisabeth G, Cepok Sabine, Chiavacci Rosetta, Clerget-Darpoux Françoise, Clysters Katleen, Comi Giancarlo, Cossburn Mark, Cournu-Rebeix Isabelle, Cox Mathew B, Cozen Wendy, Cree Bruce A C, Cross Anne H, Cusi Daniele, Daly Mark J, Davis Emma, de Bakker Paul I W, Debouverie Marc, D'hooghe Marie Beatrice, Dixon Katherine, Dobosi Rita, Dubois Bénédicte, Ellinghaus David, Elovaara Irina, Esposito Federica, Fontenille Claire, Foote Simon, Franke Andre, Galimberti Daniela, Ghezzi Angelo, Glessner Joseph, Gomez Refujia, Gout Olivier, Graham Colin, Grant Struan F A, Guerini Franca Rosa, Hakonarson Hakon, Hall Per, Hamsten Anders, Hartung Hans-Peter, Heard Rob N, Heath Simon, Hobart Jeremy, Hoshi Muna, Infante-Duarte Carmen, Ingram Gillian, Ingram Wendy, Islam Talat, Jagodic Maja, Kabesch Michael, Kermode Allan G, Kilpatrick Trevor J, Kim Cecilia, Klopp Norman, Koivisto Keijo, Larsson Malin, Lathrop Mark, Lechner-Scott Jeannette S, Leone Maurizio A, Leppä Virpi, Liljedahl Ulrika, Bomfim Izaura Lima, Lincoln Robin R, Link Jenny, Liu Jianjun, Lorentzen Aslaug R, Lupoli Sara, Macciardi Fabio, Mack Thomas, Marriott Mark, Martinelli Vittorio, Mason Deborah, McCauley Jacob L, Mentch Frank, Mero Inger-Lise, Mihalova Tania, Montalban Xavier, Mottershead John, Myhr Kjell-Morten, Naldi Paola, Ollier William, Page Alison, Palotie Aarno, Pelletier Jean, Piccio Laura, Pickersgill Trevor, Piehl Fredrik, Pobywajlo Susan, Quach Hong L, Ramsay Patricia P, Reunanen Mauri, Reynolds Richard, Rioux John D, Rodegher Mariaemma, Roesner Sabine, Rubio Justin P, Rückert Ina-Maria, Salvetti Marco, Salvi Erika, Santaniello Adam, Schaefer Catherine A, Schreiber Stefan, Schulze Christian, Scott Rodney J, Sellebjerg Finn, Selmaj Krzysztof W, Sexton David, Shen Ling, Simms-Acuna Brigid, Skidmore Sheila, Sleiman Patrick M A, Smestad Cathrine, Sørensen Per Soelberg, Søndergaard Helle Bach, Stankovich Jim, Strange Richard C, Sulonen Anna-Maija, Sundqvist Emilie, Syvänen Ann-Christine: Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 476(7359): 214-9, Aug 2011.

Höglinger Günter U, Melhem Nadine M, Dickson Dennis W, Sleiman Patrick M A, Wang Li-San, Klei Lambertus, Rademakers Rosa, de Silva Rohan, Litvan Irene, Riley David E, van Swieten John C, Heutink Peter, Wszolek Zbigniew K, Uitti Ryan J, Vandrovcova Jana, Hurtig Howard I, Gross Rachel G, Maetzler Walter, Goldwurm Stefano, Tolosa Eduardo, Borroni Barbara, Pastor Pau, Cantwell Laura B, Han Mi Ryung, Dillman Allissa, van der Brug Marcel P, Gibbs J Raphael, Cookson Mark R, Hernandez Dena G, Singleton Andrew B, Farrer Matthew J, Yu Chang-En, Golbe Lawrence I, Revesz Tamas, Hardy John, Lees Andrew J, Devlin Bernie, Hakonarson Hakon, Müller Ulrich, Schellenberg Gerard D: Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. Nature genetics 43(7): 699-705, Jul 2011.

Zhao Jianhua, Bradfield Jonathan P, Li Mingyao, Zhang Haitao, Mentch Frank D, Wang Kai, Sleiman Patrick M A, Kim Cecilia E, Glessner Joseph T, Frackelton Edward C, Chiavacci Rosetta M, Berkowitz Robert I, Zemel Babette S, Hakonarson Hakon, Grant Struan F A: BMD-associated variation at the Osterix locus is correlated with childhood obesity in females. Obesity (Silver Spring, Md.) 19(6): 1311-4, Jun 2011.

Chen-Plotkin Alice S, Martinez-Lage Maria, Sleiman Patrick M A, Hu William, Greene Robert, Wood Elisabeth McCarty, Bing Shaoxu, Grossman Murray, Schellenberg Gerard D, Hatanpaa Kimmo J, Weiner Myron F, White Charles L, Brooks William S, Halliday Glenda M, Kril Jillian J, Gearing Marla, Beach Thomas G, Graff-Radford Neill R, Dickson Dennis W, Rademakers Rosa, Boeve Bradley F, Pickering-Brown Stuart M, Snowden Julie, van Swieten John C, Heutink Peter, Seelaar Harro, Murrell Jill R, Ghetti Bernardino, Spina Salvatore, Grafman Jordan, Kaye Jeffrey A, Woltjer Randall L, Mesulam Marsel, Bigio Eileen, Lladó Albert, Miller Bruce L, Alzualde Ainhoa, Moreno Fermin, Rohrer Jonathan D, Mackenzie Ian R A, Feldman Howard H, Hamilton Ronald L, Cruts Marc, Engelborghs Sebastiaan, De Deyn Peter P, Van Broeckhoven Christine, Bird Thomas D, Cairns Nigel J, Goate Allison, Frosch Matthew P, Riederer Peter F, Bogdanovic Nenad, Lee Virginia M Y, Trojanowski John Q, Van Deerlin Vivianna M: Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration. Archives of neurology 68(4): 488-97, Apr 2011.

Lanktree Matthew B, Guo Yiran, Murtaza Muhammed, Glessner Joseph T, Bailey Swneke D, Onland-Moret N Charlotte, Lettre Guillaume, Ongen Halit, Rajagopalan Ramakrishnan, Johnson Toby, Shen Haiqing, Nelson Christopher P, Klopp Norman, Baumert Jens, Padmanabhan Sandosh, Pankratz Nathan, Pankow James S, Shah Sonia, Taylor Kira, Barnard John, Peters Bas J, Maloney Cliona M, Lobmeyer Maximilian T, Stanton Alice, Zafarmand M Hadi, Romaine Simon P R, Mehta Amar, van Iperen Erik P A, Gong Yan, Price Tom S, Smith Erin N, Kim Cecilia E, Li Yun R, Asselbergs Folkert W, Atwood Larry D, Bailey Kristian M, Bhatt Deepak, Bauer Florianne, Behr Elijah R, Bhangale Tushar, Boer Jolanda M A, Boehm Bernhard O, Bradfield Jonathan P, Brown Morris, Braund Peter S, Burton Paul R, Carty Cara, Chandrupatla Hareesh R, Chen Wei, Connell John, Dalgeorgou Chrysoula, Boer Anthonius de, Drenos Fotios, Elbers Clara C, Fang James C, Fox Caroline S, Frackelton Edward C, Fuchs Barry, Furlong Clement E, Gibson Quince, Gieger Christian, Goel Anuj, Grobbee Diederik E, Hastie Claire, Howard Philip J, Huang Guan-Hua, Johnson W Craig, Li Qing, Kleber Marcus E, Klein Barbara E K, Klein Ronald, Kooperberg Charles, Ky Bonnie, Lacroix Andrea, Lanken Paul, Lathrop Mark, Li Mingyao, Marshall Vanessa, Melander Olle, Mentch Frank D, Meyer Nuala J, Monda Keri L, Montpetit Alexandre, Murugesan Gurunathan, Nakayama Karen, Nondahl Dave, Onipinla Abiodun, Rafelt Suzanne, Newhouse Stephen J, Otieno F George, Patel Sanjey R, Putt Mary E, Rodriguez Santiago, Safa Radwan N, Sawyer Douglas B, Schreiner Pamela J, Simpson Claire, Sivapalaratnam Suthesh, Srinivasan Sathanur R, Suver Christine, Swergold Gary, Sweitzer Nancy K, Thomas Kelly A, Thorand Barbara, Timpson Nicholas J, Tischfield Sam, Tobin Martin, Tomaszewski Maciej, Tomaszweski Maciej, Verschuren W M Monique, Wallace Chris, Winkelmann Bernhard, Zhang Haitao, Zheng Dongling, Zhang Li, Zmuda Joseph M, Clarke Robert, Balmforth Anthony J, Danesh John, Day Ian N, Schork Nicholas J, de Bakker Paul I W, Delles Christian, Duggan David, Hingorani Aroon D, Hirschhorn Joel N, Hofker Marten H, Humphries Steve E, Kivimaki Mika, Lawlor Debbie A, Kottke-Marchant Kandice, Mega Jessica L, Mitchell Braxton D, Morrow David A, Palmen Jutta, Redline Susan, Shields Denis C, Shuldiner Alan R, Sleiman Patrick M, Smith George Davey, Farrall Martin, Jamshidi Yalda, Christiani David C, Casas Juan P, Hall Alistair S, Doevendans Pieter A, Christie Jason D, Berenson Gerald S, Murray Sarah S, Illig Thomas, Dorn Gerald W, Cappola Thomas P, Boerwinkle Eric, Sever Peter, Rader Daniel J, Reilly Muredach P, Caulfield Mark, Talmud Philippa J, Topol Eric, Engert James C, Wang Kai, Dominiczak Anna, Hamsten Anders, Curtis Sean P, Silverstein Roy L, Lange Leslie A, Sabatine Marc S, Trip Mieke, Saleheen Danish, Peden John F, Cruickshanks Karen J, März Winfried, O'Connell Jeffrey R, Klungel Olaf H, Wijmenga Cisca, Maitland-van der Zee Anke Hilse, Schadt Eric E, Johnson Julie A, Jarvik Gail P, Papanicolaou George J, Grant Struan F A, Munroe Patricia B, North Kari E, Samani Nilesh J, Koenig Wolfgang, Gaunt Tom R, Anand Sonia S, van der Schouw Yvonne T, Soranzo Nicole, Fitzgerald Garret A, Reiner Alex, Hegele Robert A, Hakonarson Hakon, Keating Brendan J: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. American journal of human genetics 88(1): 6-18, Jan 2011.

2010

Zhao Jianhua, Li Mingyao, Bradfield Jonathan P, Zhang Haitao, Mentch Frank D, Wang Kai, Sleiman Patrick M, Kim Cecilia E, Glessner Joseph T, Hou Cuiping, Keating Brendan J, Thomas Kelly A, Garris Maria L, Deliard Sandra, Frackelton Edward C, Otieno F George, Chiavacci Rosetta M, Berkowitz Robert I, Hakonarson Hakon, Grant Struan F A: The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. BMC medical genetics 11: 96, 2010.

Glessner Joseph T, Wang Kai, Sleiman Patrick M A, Zhang Haitao, Kim Cecilia E, Flory James H, Bradfield Jonathan P, Imielinski Marcin, Frackelton Edward C, Qiu Haijun, Mentch Frank, Grant Struan F A, Hakonarson Hakon: Duplication of the SLIT3 locus on 5q35.1 predisposes to major depressive disorder. PloS one 5(12): e15463, 2010.

Glessner Joseph T, Bradfield Jonathan P, Wang Kai, Takahashi Nagahide, Zhang Haitao, Sleiman Patrick M, Mentch Frank D, Kim Cecilia E, Hou Cuiping, Thomas Kelly A, Garris Maria L, Deliard Sandra, Frackelton Edward C, Otieno F George, Zhao Jianhua, Chiavacci Rosetta M, Li Mingyao, Buxbaum Joseph D, Berkowitz Robert I, Hakonarson Hakon, Grant Struan F A: A genome-wide study reveals copy number variants exclusive to childhood obesity cases. American journal of human genetics 87(5): 661-6, Nov 2010.

Glessner Joseph T, Reilly Muredach P, Kim Cecilia E, Takahashi Nagahide, Albano Anthony, Hou Cuiping, Bradfield Jonathan P, Zhang Haitao, Sleiman Patrick M A, Flory James H, Imielinski Marcin, Frackelton Edward C, Chiavacci Rosetta, Thomas Kelly A, Garris Maria, Otieno Frederick G, Davidson Michael, Weiser Mark, Reichenberg Abraham, Davis Kenneth L, Friedman Joseph I, Cappola Thomas P, Margulies Kenneth B, Rader Daniel J, Grant Struan F A, Buxbaum Joseph D, Gur Raquel E, Hakonarson Hakon: Strong synaptic transmission impact by copy number variations in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America 107(23): 10584-9, Jun 2010.

Wang Kai, Baldassano Robert, Zhang Haitao, Qu Hui-Qi, Imielinski Marcin, Kugathasan Subra, Annese Vito, Dubinsky Marla, Rotter Jerome I, Russell Richard K, Bradfield Jonathan P, Sleiman Patrick M A, Glessner Joseph T, Walters Thomas, Hou Cuiping, Kim Cecilia, Frackelton Edward C, Garris Maria, Doran James, Romano Claudio, Catassi Carlo, Van Limbergen Johan, Guthery Stephen L, Denson Lee, Piccoli David, Silverberg Mark S, Stanley Charles A, Monos Dimitri, Wilson David C, Griffiths Anne, Grant Struan F A, Satsangi Jack, Polychronakos Constantin, Hakonarson Hakon: Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects. Human molecular genetics 19(10): 2059-67, May 2010.

Rothenberg Marc E, Spergel Jonathan M, Sherrill Joseph D, Annaiah Kiran, Martin Lisa J, Cianferoni Antonella, Gober Laura, Kim Cecilia, Glessner Joseph, Frackelton Edward, Thomas Kelly, Blanchard Carine, Liacouras Chris, Verma Ritu, Aceves Seema, Collins Margaret H, Brown-Whitehorn Terri, Putnam Phil E, Franciosi James P, Chiavacci Rosetta M, Grant Struan F A, Abonia J Pablo, Sleiman Patrick M A, Hakonarson Hakon: Common variants at 5q22 associate with pediatric eosinophilic esophagitis. Nature genetics 42(4): 289-91, Apr 2010.

Van Deerlin Vivianna M, Sleiman Patrick M A, Martinez-Lage Maria, Chen-Plotkin Alice, Wang Li-San, Graff-Radford Neill R, Dickson Dennis W, Rademakers Rosa, Boeve Bradley F, Grossman Murray, Arnold Steven E, Mann David M A, Pickering-Brown Stuart M, Seelaar Harro, Heutink Peter, van Swieten John C, Murrell Jill R, Ghetti Bernardino, Spina Salvatore, Grafman Jordan, Hodges John, Spillantini Maria Grazia, Gilman Sid, Lieberman Andrew P, Kaye Jeffrey A, Woltjer Randall L, Bigio Eileen H, Mesulam Marsel, Al-Sarraj Safa, Troakes Claire, Rosenberg Roger N, White Charles L, Ferrer Isidro, Lladó Albert, Neumann Manuela, Kretzschmar Hans A, Hulette Christine Marie, Welsh-Bohmer Kathleen A, Miller Bruce L, Alzualde Ainhoa, Lopez de Munain Adolfo, McKee Ann C, Gearing Marla, Levey Allan I, Lah James J, Hardy John, Rohrer Jonathan D, Lashley Tammaryn, Mackenzie Ian R A, Feldman Howard H, Hamilton Ronald L, Dekosky Steven T, van der Zee Julie, Kumar-Singh Samir, Van Broeckhoven Christine, Mayeux Richard, Vonsattel Jean Paul G, Troncoso Juan C, Kril Jillian J, Kwok John B J, Halliday Glenda M, Bird Thomas D, Ince Paul G, Shaw Pamela J, Cairns Nigel J, Morris John C, McLean Catriona Ann, DeCarli Charles, Ellis William G, Freeman Stefanie H, Frosch Matthew P, Growdon John H, Perl Daniel P, Sano Mary, Bennett David A, Schneider Julie A, Beach Thomas G, Reiman Eric M, Woodruff Bryan K, Cummings Jeffrey, Vinters Harry V, Miller Carol A, Chui Helena C, Alafuzoff Irina, Hartikainen Päivi, Seilhean Danielle, Galasko Douglas, Masliah Eliezer, Cotman Carl W, Tuñón M Teresa, Martínez M Cristina Caballero, Munoz David G, Carroll Steven L, Marson Daniel, Riederer Peter F, Bogdanovic Nenad, Schellenberg Gerard D, Hakonarson Hakon, Trojanowski John Q, Lee Virginia M-Y: Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nature genetics 42(3): 234-9, Mar 2010.

Mathias Rasika A, Grant Audrey V, Rafaels Nicholas, Hand Tracey, Gao Li, Vergara Candelaria, Tsai Yuhjung J, Yang Mao, Campbell Monica, Foster Cassandra, Gao Peisong, Togias A, Hansel Nadia N, Diette Gregory, Adkinson N Franklin, Liu Mark C, Faruque Mezbah, Dunston Georgia M, Watson Harold R, Bracken Michael B, Hoh Josephine, Maul Pissamai, Maul Trevor, Jedlicka Anne E, Murray Tanda, Hetmanski Jacqueline B, Ashworth Roxann, Ongaco Chrissie M, Hetrick Kurt N, Doheny Kimberly F, Pugh Elizabeth W, Rotimi Charles N, Ford Jean, Eng Celeste, Burchard Esteban G, Sleiman Patrick M A, Hakonarson Hakon, Forno Erick, Raby Benjamin A, Weiss Scott T, Scott Alan F, Kabesch Michael, Liang Liming, Abecasis Gonçalo, Moffatt Miriam F, Cookson William O C, Ruczinski Ingo, Beaty Terri H, Barnes Kathleen C: A genome-wide association study on African-ancestry populations for asthma. The Journal of allergy and clinical immunology 125(2): 336-346.e4, Feb 2010.

Sleiman Patrick M A, Flory James, Imielinski Marcin, Bradfield Jonathan P, Annaiah Kiran, Willis-Owen Saffron A G, Wang Kai, Rafaels Nicholas M, Michel Sven, Bonnelykke Klaus, Zhang Haitao, Kim Cecilia E, Frackelton Edward C, Glessner Joseph T, Hou Cuiping, Otieno F George, Santa Erin, Thomas Kelly, Smith Ryan M, Glaberson Wendy R, Garris Maria, Chiavacci Rosetta M, Beaty Terri H, Ruczinski Ingo, Orange Jordan S, Orange Jordan M, Allen Julian, Spergel Jonathan M, Grundmeier Robert, Mathias Rasika A, Christie Jason D, von Mutius Erika, Cookson William O C, Kabesch Michael, Moffatt Miriam F, Grunstein Michael M, Barnes Kathleen C, Devoto Marcella, Magnusson Mark, Li Hongzhe, Grant Struan F A, Bisgaard Hans, Hakonarson Hakon: Variants of DENND1B associated with asthma in children. The New England journal of medicine 362(1): 36-44, Jan 2010.

2009

Imielinski Marcin, Baldassano Robert N, Griffiths Anne, Russell Richard K, Annese Vito, Dubinsky Marla, Kugathasan Subra, Bradfield Jonathan P, Walters Thomas D, Sleiman Patrick, Kim Cecilia E, Muise Aleixo, Wang Kai, Glessner Joseph T, Saeed Shehzad, Zhang Haitao, Frackelton Edward C, Hou Cuiping, Flory James H, Otieno George, Chiavacci Rosetta M, Grundmeier Robert, Castro Massimo, Latiano Anna, Dallapiccola Bruno, Stempak Joanne, Abrams Debra J, Taylor Kent, McGovern Dermot, Silber Gary, Wrobel Iwona, Quiros Antonio, Barrett Jeffrey C, Hansoul Sarah, Nicolae Dan L, Cho Judy H, Duerr Richard H, Rioux John D, Brant Steven R, Silverberg Mark S, Taylor Kent D, Barmuda M Michael, Bitton Alain, Dassopoulos Themistocles, Datta Lisa Wu, Green Todd, Griffiths Anne M, Kistner Emily O, Murtha Michael T, Regueiro Miguel D, Rotter Jerome I, Schumm L Philip, Steinhart A Hillary, Targan Stephen R, Xavier Ramnik J, Libioulle Cécile, Sandor Cynthia, Lathrop Mark, Belaiche Jacques, Dewit Olivier, Gut Ivo, Heath Simon, Laukens Debby, Mni Myriam, Rutgeerts Paul, Van Gossum André, Zelenika Diana, Franchimont Denis, Hugot J P, de Vos Martine, Vermeire Severine, Louis Edouard, Cardon Lon R, Anderson Carl A, Drummond Hazel, Nimmo Elaine, Ahmad Tariq, Prescott Natalie J, Onnie Clive M, Fisher Sheila A, Marchini Jonathan, Ghori Jilur, Bumpstead Suzannah, Gwillam Rhian, Tremelling Mark, Delukas Panos, Mansfield John, Jewell Derek, Satsangi Jack, Mathew Christopher G, Parkes Miles, Georges Michel, Daly Mark J, Heyman Melvin B, Ferry George D, Kirschner Barbara, Lee Jessica, Essers Jonah, Grand Richard, Stephens Michael, Levine Arie, Piccoli David, Van Limbergen John, Cucchiara Salvatore, Monos Dimitri S, Guthery Stephen L, Denson Lee, Wilson David C, Grant Straun F A, Daly Mark, Silverberg Mark S, Satsangi Jack, Hakonarson Hakon: Common variants at five new loci associated with early-onset inflammatory bowel disease. Nature genetics 41(12): 1335-40, Dec 2009.

da Costa Cristine Alves, Sunyach Claire, Giaime Emilie, West Andrew, Corti Olga, Brice Alexis, Safe Stephen, Abou-Sleiman Patrick M, Wood Nicholas W, Takahashi Hitoshi, Goldberg Mathew S, Shen Jie, Checler Frédéric: Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease. Nature cell biology 11(11): 1370-5, Nov 2009.

Zhao Jianhua, Li Mingyao, Bradfield Jonathan P, Wang Kai, Zhang Haitao, Sleiman Patrick, Kim Cecilia E, Annaiah Kiran, Glaberson Wendy, Glessner Joseph T, Otieno F George, Thomas Kelly A, Garris Maria, Hou Cuiping, Frackelton Edward C, Chiavacci Rosetta M, Berkowitz Robert I, Hakonarson Hakon, Grant Struan F A: Examination of type 2 diabetes loci implicates CDKAL1 as a birth weight gene. Diabetes 58(10): 2414-8, Oct 2009.

Vandrovcova Jana, Pittman Alan M, Malzer Elke, Abou-Sleiman Patrick M, Lees Andrew J, Wood Nicholas W, de Silva Rohan: Association of MAPT haplotype-tagging SNPs with sporadic Parkinson's disease. Neurobiology of aging 30(9): 1477-82, Sep 2009.

Flory James H, Sleiman Patrick M, Christie Jason D, Annaiah Kiran, Bradfield Jonathan, Kim Cecilia E, Glessner Joseph, Imielinski Marcin, Li Hongzhe, Frackelton Edward C, Cuiping Hou, Otieno George, Thomas Kelly, Smith Ryan, Glaberson Wendy, Garris Maria, Chiavacci Rosetta, Allen Julian, Spergel Jonathan, Grundmeier Robert, Grunstein Michael, Magnusson Michael, Grant Struan F A, Bønnelykke Klaus, Bisgaard Hans, Hakonarson Hakon: 17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry. The Journal of allergy and clinical immunology 124(3): 605-7, Sep 2009.

Sleiman P M A, Healy D G, Muqit M M K, Yang Y X, Van Der Brug M, Holton J L, Revesz T, Quinn N P, Bhatia K, Diss J K J, Lees A J, Cookson M R, Latchman D S, Wood N W: Characterisation of a novel NR4A2 mutation in Parkinson's disease brain. Neuroscience letters 457(2): 75-9, Jun 2009.

Wang Kai, Zhang Haitao, Ma Deqiong, Bucan Maja, Glessner Joseph T, Abrahams Brett S, Salyakina Daria, Imielinski Marcin, Bradfield Jonathan P, Sleiman Patrick M A, Kim Cecilia E, Hou Cuiping, Frackelton Edward, Chiavacci Rosetta, Takahashi Nagahide, Sakurai Takeshi, Rappaport Eric, Lajonchere Clara M, Munson Jeffrey, Estes Annette, Korvatska Olena, Piven Joseph, Sonnenblick Lisa I, Alvarez Retuerto Ana I, Herman Edward I, Dong Hongmei, Hutman Ted, Sigman Marian, Ozonoff Sally, Klin Ami, Owley Thomas, Sweeney John A, Brune Camille W, Cantor Rita M, Bernier Raphael, Gilbert John R, Cuccaro Michael L, McMahon William M, Miller Judith, State Matthew W, Wassink Thomas H, Coon Hilary, Levy Susan E, Schultz Robert T, Nurnberger John I, Haines Jonathan L, Sutcliffe James S, Cook Edwin H, Minshew Nancy J, Buxbaum Joseph D, Dawson Geraldine, Grant Struan F A, Geschwind Daniel H, Pericak-Vance Margaret A, Schellenberg Gerard D, Hakonarson Hakon: Common genetic variants on 5p14.1 associate with autism spectrum disorders. Nature 459(7246): 528-33, May 2009.

Himes Blanca E, Hunninghake Gary M, Baurley James W, Rafaels Nicholas M, Sleiman Patrick, Strachan David P, Wilk Jemma B, Willis-Owen Saffron A G, Klanderman Barbara, Lasky-Su Jessica, Lazarus Ross, Murphy Amy J, Soto-Quiros Manuel E, Avila Lydiana, Beaty Terri, Mathias Rasika A, Ruczinski Ingo, Barnes Kathleen C, Celedón Juan C, Cookson William O C, Gauderman W James, Gilliland Frank D, Hakonarson Hakon, Lange Christoph, Moffatt Miriam F, O'Connor George T, Raby Benjamin A, Silverman Edwin K, Weiss Scott T: Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. American journal of human genetics 84(5): 581-93, May 2009.

Glessner Joseph T, Wang Kai, Cai Guiqing, Korvatska Olena, Kim Cecilia E, Wood Shawn, Zhang Haitao, Estes Annette, Brune Camille W, Bradfield Jonathan P, Imielinski Marcin, Frackelton Edward C, Reichert Jennifer, Crawford Emily L, Munson Jeffrey, Sleiman Patrick M A, Chiavacci Rosetta, Annaiah Kiran, Thomas Kelly, Hou Cuiping, Glaberson Wendy, Flory James, Otieno Frederick, Garris Maria, Soorya Latha, Klei Lambertus, Piven Joseph, Meyer Kacie J, Anagnostou Evdokia, Sakurai Takeshi, Game Rachel M, Rudd Danielle S, Zurawiecki Danielle, McDougle Christopher J, Davis Lea K, Miller Judith, Posey David J, Michaels Shana, Kolevzon Alexander, Silverman Jeremy M, Bernier Raphael, Levy Susan E, Schultz Robert T, Dawson Geraldine, Owley Thomas, McMahon William M, Wassink Thomas H, Sweeney John A, Nurnberger John I, Coon Hilary, Sutcliffe James S, Minshew Nancy J, Grant Struan F A, Bucan Maja, Cook Edwin H, Buxbaum Joseph D, Devlin Bernie, Schellenberg Gerard D, Hakonarson Hakon: Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. Nature 459(7246): 569-73, May 2009.

Wang Kai, Zhang Haitao, Kugathasan Subra, Annese Vito, Bradfield Jonathan P, Russell Richard K, Sleiman Patrick M A, Imielinski Marcin, Glessner Joseph, Hou Cuiping, Wilson David C, Walters Thomas, Kim Cecilia, Frackelton Edward C, Lionetti Paolo, Barabino Arrigo, Van Limbergen Johan, Guthery Stephen, Denson Lee, Piccoli David, Li Mingyao, Dubinsky Marla, Silverberg Mark, Griffiths Anne, Grant Struan F A, Satsangi Jack, Baldassano Robert, Hakonarson Hakon: Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease. American journal of human genetics 84(3): 399-405, Mar 2009.

Bisgaard Hans, Bønnelykke Klaus, Sleiman Patrick M A, Brasholt Martin, Chawes Bo, Kreiner-Møller Eskil, Stage Malene, Kim Cecilia, Tavendale Roger, Baty Florent, Pipper Christian Bressen, Palmer Colin N A, Hakonarsson Hakon: Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood. American journal of respiratory and critical care medicine 179(3): 179-85, Feb 2009.

2008

Sleiman Patrick M A, Annaiah Kiran, Imielinski Marcin, Bradfield Jonathan P, Kim Cecilia E, Frackelton Edward C, Glessner Joseph T, Eckert Andrew W, Otieno F George, Santa Erin, Thomas Kelly, Smith Ryan M, Glaberson Wendy, Garris Maria, Gunnlaugsson Sigfus, Chiavacci Rosetta M, Allen Julian, Spergel Jonathan, Grundmeier Robert, Grunstein Michael M, Magnusson Mark, Bisgaard Hans, Grant Struan F A, Hakonarson Hakon: ORMDL3 variants associated with asthma susceptibility in North Americans of European ancestry. The Journal of allergy and clinical immunology 122(6): 1225-7, Dec 2008.

Hargreaves Iain P, Lane Amelia, Sleiman Patrick M A: The coenzyme Q10 status of the brain regions of Parkinson's disease patients. Neuroscience letters 447(1): 17-9, Dec 2008.

Mortiboys Heather, Thomas Kelly Jean, Koopman Werner J H, Klaffke Stefanie, Abou-Sleiman Patrick, Olpin Simon, Wood Nicholas W, Willems Peter H G M, Smeitink Jan A M, Cookson Mark R, Bandmann Oliver: Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts. Annals of neurology 64(5): 555-65, Nov 2008.

Kugathasan Subra, Baldassano Robert N, Bradfield Jonathan P, Sleiman Patrick M A, Imielinski Marcin, Guthery Stephen L, Cucchiara Salvatore, Kim Cecilia E, Frackelton Edward C, Annaiah Kiran, Glessner Joseph T, Santa Erin, Willson Tara, Eckert Andrew W, Bonkowski Erin, Shaner Julie L, Smith Ryan M, Otieno F George, Peterson Nicholas, Abrams Debra J, Chiavacci Rosetta M, Grundmeier Robert, Mamula Petar, Tomer Gitit, Piccoli David A, Monos Dimitri S, Annese Vito, Denson Lee A, Grant Struan F A, Hakonarson Hakon: Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. Nature genetics 40(10): 1211-5, Oct 2008.

Silveira-Moriyama L, Guedes L C, Kingsbury A, Ayling H, Shaw K, Barbosa E R, Bonifati V, Quinn N P, Abou-Sleiman P, Wood N W, Petrie A, Sampaio C, Ferreira J J, Holton J, Revesz T, Lees A J: Hyposmia in G2019S LRRK2-related parkinsonism: clinical and pathologic data. Neurology 71(13): 1021-6, Sep 2008.

Tazir M, Ysmail-Dahlouk F, Bélarbi S, Hecham N, Barbosa E, Chien HF, Rieder CR, Jardim LB, Rogaeva E, Lesage S, Lohmann E, Vidailhet M, Bonnet AM, Agid Y, Pollak P, Tison F, Durif F, Broussolle E, Berg D, Hagenah J, Gosal D, Gibson M, Vanacore N, Berardelli A, Fabrini G, Fabrizio E, Meco G, Stocchi F, Dalla Libera A, De Mari M, Lamberti P, Cossu G, Pezzoli G, Zini M, Tesei S, Zecchinelli A, Sironi F, Antonini A, Mariani C, Sacilotto G, Meucci N, Canesi M, Di Fonzo A, Oostra B, Correia Guedes L, Rosa MM, Coelho M, Sampaio C, Gaig C, Lu CS, Wu-Chou YH, Quinn NP, Abou-Sleiman PM, Muqit MM, Khan NL, Gandhi S, Vaughan J, Payami H, Nutt JJ, Factor SA, Higgins DS, Farrer MJ, Hulihan M, Brown L, Mata IF, Samii A, Yearout D, Griffith A, Leis BC, Roberts JW.: Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study. Lancet neurology 7(7): 583-90, Jul 2008.

2007

McKenzie Matthew, Liolitsa Danae, Akinshina Natalya, Campanella Michelangelo, Sisodiya Sanjay, Hargreaves Ian, Nirmalananthan Niranjanan, Sweeney Mary G, Abou-Sleiman Patrick M, Wood Nicholas W, Hanna Michael G, Duchen Michael R: Mitochondrial ND5 gene variation associated with encephalomyopathy and mitochondrial ATP consumption. The Journal of biological chemistry 282(51): 36845-52, Dec 2007.

2006

Marques Vanessa D, Barreira Amilton A, Davis Mary B, Abou-Sleiman Patrick M, Silva Wilson A, Zago Marco A, Sobreira Claudia, Fazan Valéria, Marques Wilson: Expanding the phenotypes of the Pro56Ser VAPB mutation: proximal SMA with dysautonomia. Muscle & nerve 34(6): 731-9, Dec 2006.

Healy Daniel G, Abou-Sleiman Patrick M, Ahmadi Kourosh R, Gandhi Sonia, Muqit Miratul M, Bhatia Kailash P, Quinn Niall P, Lees Andrew J, Holton Janice L, Revesz Tamas, Wood Nicholas W: NR4A2 genetic variation in sporadic Parkinson's disease: a genewide approach. Movement disorders : official journal of the Movement Disorder Society 21(11): 1960-3, Nov 2006.

Abou-Sleiman Patrick M, Muqit Miratul M K, McDonald Neil Q, Yang Yan Xiang, Gandhi Sonia, Healy Daniel G, Harvey Kirsten, Harvey Robert J, Deas Emma, Bhatia Kailash, Quinn Niall, Lees Andrew, Latchman David S, Wood Nicholas W: A heterozygous effect for PINK1 mutations in Parkinson's disease? Annals of neurology 60(4): 414-9, Oct 2006.

Muqit Miratul M K, Abou-Sleiman Patrick M, Saurin Adrian T, Harvey Kirsten, Gandhi Sonia, Deas Emma, Eaton Simon, Payne Smith Martin D, Venner Kerrie, Matilla Antoni, Healy Daniel G, Gilks William P, Lees Andrew J, Holton Janice, Revesz Tamas, Parker Peter J, Harvey Robert J, Wood Nicholas W, Latchman David S: Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress. Journal of neurochemistry 98(1): 156-69, Jul 2006.

Gandhi S, Muqit M M K, Stanyer L, Healy D G, Abou-Sleiman P M, Hargreaves I, Heales S, Ganguly M, Parsons L, Lees A J, Latchman D S, Holton J L, Wood N W, Revesz T: PINK1 protein in normal human brain and Parkinson's disease. Brain : a journal of neurology 129(Pt 7): 1720-31, Jul 2006.

Ozawa T, Healy D G, Abou-Sleiman P M, Ahmadi K R, Quinn N, Lees A J, Shaw K, Wullner U, Berciano J, Moller J C, Kamm C, Burk K, Josephs K A, Barone P, Tolosa E, Goldstein D B, Wenning G, Geser F, Holton J L, Gasser T, Revesz T, Wood N W: The alpha-synuclein gene in multiple system atrophy. Journal of neurology, neurosurgery, and psychiatry 77(4): 464-7, Apr 2006.

Healy Daniel G, Abou-Sleiman Patrick M, Casas Juan P, Ahmadi Kourosh R, Lynch Timothy, Gandhi Sonia, Muqit Miratul M K, Foltynie Thomas, Barker Roger, Bhatia Kailash P, Quinn Niall P, Lees Andrew J, Gibson J Mark, Holton Janice L, Revesz Tamas, Goldstein David B, Wood Nicholas W: UCHL-1 is not a Parkinson's disease susceptibility gene. Annals of neurology 59(4): 627-33, Apr 2006.

2005

Khan Naheed L, Jain Shushant, Lynch John M, Pavese Nicola, Abou-Sleiman Patrick, Holton Janice L, Healy Daniel G, Gilks William P, Sweeney Mary G, Ganguly Milan, Gibbons Vaneesha, Gandhi Sonia, Vaughan Jenny, Eunson Louise H, Katzenschlager Regina, Gayton Juliet, Lennox Graham, Revesz Tamas, Nicholl David, Bhatia Kailash P, Quinn Niall, Brooks David, Lees Andrew J, Davis Mary B, Piccini Paola, Singleton Andrew B, Wood Nicholas W: Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data. Brain : a journal of neurology 128(Pt 12): 2786-96, Dec 2005.

Pittman A M, Myers A J, Abou-Sleiman P, Fung H C, Kaleem M, Marlowe L, Duckworth J, Leung D, Williams D, Kilford L, Thomas N, Morris C M, Dickson D, Wood N W, Hardy J, Lees A J, de Silva R: Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration. Journal of medical genetics 42(11): 837-46, Nov 2005.

Healy Daniel G, Abou-Sleiman Patrick M, Quinn Niall, Ahmadi Kourosh R, Ozawa Tetsutaro, Kamm Christoph, Wullner Ullrich, Oertel Wolfgang H, Burk Katrin, Dupont Erik, Pellecchia Maria T, Tolosa Eduardo, Gasser Thomas, Holton Janice L, Revesz Tamas, Goldstein David B, Lees Andrew J, Wood Nicholas W: UCHL-1 gene in multiple system atrophy: a haplotype tagging approach. Movement disorders : official journal of the Movement Disorder Society 20(10): 1338-43, Oct 2005.

Gilks William P, Abou-Sleiman Patrick M, Gandhi Sonia, Jain Shushant, Singleton Andrew, Lees Andrew J, Shaw Karen, Bhatia Kailash P, Bonifati Vincenzo, Quinn Niall P, Lynch John, Healy Daniel G, Holton Janice L, Revesz Tamas, Wood Nicholas W: A common LRRK2 mutation in idiopathic Parkinson's disease. Lancet 365(9457): 415-6, Jan 29-Feb 4 2005.

2004

Marques W, Davis M B, Abou-Sleiman P M, Marques V D, Silva Jr W A, Zago M A, Sobreira C S, Barreira A A: Hereditary motor and autonomic neuronopathy 1 maps to chromosome 20q13.2-13.3. Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 37(11): 1757-62, Nov 2004.

Healy D G, Abou-Sleiman P M, Gibson J M, Ross O A, Jain S, Gandhi S, Gosal D, Muqit M M K, Wood N W, Lynch T: PINK1 (PARK6) associated Parkinson disease in Ireland. Neurology 63(8): 1486-8, Oct 2004.

Healy Daniel G, Abou-Sleiman Patrick M, Ahmadi Kourosh R, Muqit Miratul M K, Bhatia Kailash P, Quinn Niall P, Lees Andrew J, Latchmann David S, Goldstein David B, Wood Nicholas W: The gene responsible for PARK6 Parkinson's disease, PINK1, does not influence common forms of parkinsonism. Annals of neurology 56(3): 329-35, Sep 2004.

Healy D G, Abou-Sleiman P M, Lees A J, Casas J P, Quinn N, Bhatia K, Hingorani A D, Wood N W: Tau gene and Parkinson's disease: a case-control study and meta-analysis. Journal of neurology, neurosurgery, and psychiatry 75(7): 962-5, Jul 2004.

Pittman Alan M, Myers Amanda J, Duckworth Jaime, Bryden Leslie, Hanson Melissa, Abou-Sleiman Patrick, Wood Nicholas W, Hardy John, Lees Andrew, de Silva Rohan: The structure of the tau haplotype in controls and in progressive supranuclear palsy. Human molecular genetics 13(12): 1267-74, Jun 2004.

Healy Daniel G, Abou-Sleiman Patrick M, Jain Shushant, Ahmadi Kourosh R, Wood Nicholas W: Assessment of a DJ-1 (PARK7) polymorphism in Finnish PD. Neurology 62(12): 2335, Jun 2004.

Valente Enza Maria, Abou-Sleiman Patrick M, Caputo Viviana, Muqit Miratul M K, Harvey Kirsten, Gispert Suzana, Ali Zeeshan, Del Turco Domenico, Bentivoglio Anna Rita, Healy Daniel G, Albanese Alberto, Nussbaum Robert, González-Maldonado Rafael, Deller Thomas, Salvi Sergio, Cortelli Pietro, Gilks William P, Latchman David S, Harvey Robert J, Dallapiccola Bruno, Auburger Georg, Wood Nicholas W: Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science (New York, N.Y.) 304(5674): 1158-60, May 2004.

Healy Daniel G, Abou-Sleiman Patrick M, Ozawa Tetsutaro, Lees Andrew J, Bhatia Kailash, Ahmadi Kourosh R, Wullner Ullrich, Berciano Jose, Moller J Carsten, Kamm Christoph, Burk Katrin, Barone Paolo, Tolosa Eduardo, Quinn Niall, Goldstein David B, Wood Nicholas W, Barrone Paolo: A functional polymorphism regulating dopamine beta-hydroxylase influences against Parkinson's disease. Annals of neurology 55(3): 443-6, Mar 2004.

Bandopadhyay Rina, Kingsbury Ann E, Cookson Mark R, Reid Andrew R, Evans Ian M, Hope Andrew D, Pittman Alan M, Lashley Tammaryn, Canet-Aviles Rosa, Miller David W, McLendon Chris, Strand Catherine, Leonard Andrew J, Abou-Sleiman Patrick M, Healy Daniel G, Ariga Hiroyashi, Wood Nicholas W, de Silva Rohan, Revesz Tamas, Hardy John A, Lees Andrew J: The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease. Brain : a journal of neurology 127(Pt 2): 420-30, Feb 2004.

Healy D G, Abou-Sleiman P M, Valente E M, Gilks W P, Bhatia K, Quinn N, Lees A J, Wood N W: DJ-1 mutations in Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry 75(1): 144-5, Jan 2004.

2003

Abou-Sleiman Patrick M, Healy Daniel G, Quinn Niall, Lees Andrew J, Wood Nicholas W: The role of pathogenic DJ-1 mutations in Parkinson's disease. Annals of neurology 54(3): 283-6, Sep 2003.

2002

Patrikidou Anna, Bennett Jon, Abou-Sleiman Patrick, Delhanty Joy D A, Harris Malcolm: A novel, de novo germline TP53 mutation in a rare presentation of the Li-Fraumeni syndrome in the maxilla. Oral oncology 38(4): 383-90, Jun 2002.

Harper Joyce C, Wells Dagan, Piyamongkol Wirawit, Abou-Sleiman Patrick, Apessos Angela, Ioulianos Antonis, Davis Mary, Doshi Alpesh, Serhal Paul, Ranieri Massimo, Rodeck Charles, Delhanty Joy D A: Preimplantation genetic diagnosis for single gene disorders: experience with five single gene disorders. Prenatal diagnosis 22(6): 525-33, Jun 2002.

Abou-Sleiman P M, Apessos A, Harper J C, Serhal P, Winston R M L, Delhanty J D A: First application of preimplantation genetic diagnosis to neurofibromatosis type 2 (NF2). Prenatal diagnosis 22(6): 519-24, Jun 2002.

Abou-Sleiman P M, Apessos A, Harper J C, Serhal P, Delhanty J D A: Pregnancy following preimplantation genetic diagnosis for Crouzon syndrome. Molecular human reproduction 8(3): 304-9, Mar 2002.

2001

Apessos A, Abou-Sleiman P M, Harper J C, Delhanty J D: Preimplantation genetic diagnosis of the fragile X syndrome by use of linked polymorphic markers. Prenatal diagnosis 21(6): 504-11, Jun 2001.

2000

Sütterlin M W, Sleiman P A, Price E, Onadim Z, Delhanty J: Dde I RFLP may falsify linkage analysis of hereditary retinoblastoma when using SSCP of p88PR0.6 region. Anticancer research 20(6D): 5233-6, Nov-Dec 2000.

1999

Sütterlin M, Sleiman P A, Onadim Z, Delhanty J: Single cell detection of inherited retinoblastoma predisposition. Prenatal diagnosis 19(13): 1231-6, Dec 1999.

Abstracts

2015

M. March; P. M. A. Sleiman; J. McElwee; D. Diogo; F. Mentch; K. Thomas; C. Hou; C. Kim; H. Hakonarson: Association of rs6967330, a functional variant of CDHR3, with asthma exacerbation and rhinovirus infections in African Americans. ASHG 2015.

Books

2013

Sleiman P., March M., Hakonarson H: The Genetic Basis of Sleep and Sleep Disorders. Cambridge University Press. Paul Shaw, Mehdi Tafti, Michael Thorpy  (eds.). 2013.

Hakonarson H. March M.E. Sleiman P.M.A. : Emery and Rimoin's Principles and Practice of Medical Genetics, 6th edition. Elsevier. David L. Rimoin, Reed E. Pyeritz, Bruce Korf  (eds.). 2013.

Hakonarson H. March M.E. Sleiman P.M.A. : Emery and Rimoin's Essential Medical Genetics. Elsevier. David L. Rimoin, Reed E. Pyeritz, Bruce Korf  (eds.). 2013.

2007

Sleiman P.M., Muqit M.M.K., Wood N.W. : Parkinson's Disease: Genetics and Pathogenesis. Informa Healthcare. Ted Dawson (eds.). 2007.

Posters and Presentations

2015

Z. Wei; X. Chang; L. Lima; T. Wang; A. Cederquist; E. Ryan; J. Garifallou; M. Khan; Y. Liu; J. Li; P. Sleiman; H. Haknonarson: Genetic risk variants converge in NMDAR interactome underlying schizophrenia. American Society of Human Genetics, Baltimore, MD  October 2015 Notes: Poster.

Y. Zhang; L. Tian; P. Sleiman; H. Hakonarson : Reanalysis of 15 Genome-wide Association Data Sets Revealed Novel Inflammatory Bowel Disease Loci. American Society of Human Genetics, Baltimore, MD  October 2015 Notes: Poster.

Y. Liu; X. Chang; P. Sleiman; H. Hakonarson : Non-coding RNA dysregulation in schizophrenia patients observed in the amygdala region based on RNA-sequencing. American Society of Human Genetics, Baltimore, MD  October 2015 Notes: Poster.

X. Chang; L. McDaniel; C. Hou; M. Diamond; K. Thomas; J. Li; Y. Guo; F. Mentch; H. Qiu; C. Kim; S. Diskin; P. Sleiman; E. Attiyeh; J. Maris; H. Hakonarson: Common variants in MMP20 at 11q22.2 predispose to 11q deletion and impact neuroblastoma risk. American Society of Human Genetics, Baltimore, MD October 2015 Notes: Podium.

R. Pellegrino; B. Almoguera; L. Vazquez; D. Abrams; T. Watanabe; L. Tiang; J. Garifallou; F. Mafra; J. Conolly; F. Mentch; P. Sleiman; H. Hakonarson : Rare variants in ALOX5 may be associated with the risk of hypersensitivity reaction to penicillin. American Society of Human Genetics, Baltimore, MD  October 2015 Notes: Poster.

P. Sleiman; B. Almoguera; J. Connolly; F. Mentch; L. Vazquez; E. Hysinger; H. Hakonarson; The electronic Medical Records and Genomics (eMERGE) Network: Common Variants in PTGES Associated with Asthma Susceptibility in African Americans. American Society of Human Genetics, Baltimore, MD  October 2015 Notes: Poster.

M. Bakay; J. Li; I. Fung; J. T. Glessner; R. Pandey; Z. Wei; F. D. Mentch; R. Pellegrino; T. Wang; C. Kim; C. Hou; F. Wang; R. M. Chiavacci; K. A. Thomas; J. M. Spergel; H. Hakonarson; P. Sleiman: Copy Number Variations in CTNNA3 and RBFOX1 Associate with Pediatric Food Allergy. American Society of Human Genetics, Baltimore, MD October 2015 Notes: Poster.

L. Vazquez; B. Almoguera; J. Connolly; P. Sleiman; F. Mentch; J. Linneman; M. Brilliant; M. Williams; K. Borthwick; A. Sundaresan; H. Hakonarson : A meta-analysis of atopic dermatitis reveals novel loci. American Society of Human Genetics, Baltimore, MD  October 2015 Notes: Poster.

K. Nguyen; D. Li; L. Tian; R. Pellegrino da Silva; C. Kao; R. Pandey; M. Bakay; P. Sleiman; H. Hakonarson : In silico analyses of complex systems for the development of novel therapeutics in rare and orphan diseases. American Society of Human Genetics, Baltimore, MD  October 2015 Notes: Poster.

J. J. Connolly; B. Almoguera; F. Mentch; L. Vazquez; D. J. Abrams; P. Sleiman; T. Lingren; B. Namjou; T. Froehlich; J. B. Harley; H. Hakonarson; The Electronic Medical Records and Genomics (eMERGE) Network : Variants in CNTN5 Associated with ADHD Susceptibility: A Meta-Analysis of Two Pediatric Cohorts. American Society of Human Genetics, Baltimore, MD  October 2015 Notes: Poster.

B. Almoguera; L. Vazquez; D. Abrams; T. Watanabe; L. Tiang; R. Pellegrino; J. Garifallou; F. Mafra; J. Connolly; F. Mentch; P. Sleiman; H. Hakonarson : Investigation of the role of rare variation in eighty-two pharmacogenes in the risk of vincristine-induced peripheral neuropathy in children. American Society of Human Genetics, Baltimore, MD  October 2015 Notes: Poster.

Invited Lectures

2015

Sleiman P A. Results from GWAS Using Imputed Data from All Sites eMERGE Network, Steering Committee Meeting, Bethesda, MD, Mar, 2015