Research News from CHOP

Children’s Hospital of Philadelphia Researchers Demonstrate that Doula and Midwife Support for Mothers in the Neonatal Intensive Care Unit Improves Postpartum Care
In a new study, researchers at Children’s Hospital of Philadelphia (CHOP) showed that partnering with doulas and midwives to support mothers with newborns in the Neonatal Intensive Care Unit (NICU) significantly improves access to timely, essential health services during a critical period of care.

CHOP Hosts Cure Sickle Cell Walk & Family Fun Day Presented by West Pharmaceutical Services, Raising More Than $242,000 for Research and Care
Children’s Hospital of Philadelphia (CHOP) hosted the Cure Sickle Cell Walk & Family Fun Day presented by West Pharmaceutical Services on Saturday, June7. It was a morning of walking, cheering and celebrating sickle cell warriors and their families at Citizens Bank Park. The event, which included a ceremonial walk to honor those with sickle cell disease, along with fun activities for the whole family, raised more than $242,000 for sickle cell disease research and patient care.
Children’s Hospital of Philadelphia Researchers Spotlight Adults with Hypoplastic Left Heart Syndrome (HLHS) Thriving Without Transplants
CHOP researchers reported long-term clinical outcomes for the largest single center cohort of individuals who underwent complex reconstructive surgery for hypoplastic left heart syndrome as newborns. In this cohort, more than 30% survived without a transplant to at least 35 years of age.
Children’s Hospital of Philadelphia Researchers Find AI to Be a Valuable Diagnostic Aid in Liver Ultrasound Analysis
Researchers at Children’s Hospital of Philadelphia (CHOP) found that the artificial intelligence (AI) chatbot, CHATGPT-4, showed promise as a viable tool to enhance ultrasound image analysis, effectively differentiating liver pathologies.
Walk for Hope Generates Over $215,000 for CHOP’s Center for Pediatric Inflammatory Bowel Disease
Earlier this month, Children’s Hospital of Philadelphia (CHOP) hosted its 16th annual Walk for Hope benefiting the Center for Pediatric Inflammatory Bowel Disease (IBD) at CHOP, raising more than $215,000 and sparking hope for a cure to IBD.
Children’s Hospital of Philadelphia Researchers Find Evidence That Tumor Necrosis Factor Alpha Helps Reduce Anemic Inflammation
Researchers at Children’s Hospital of Philadelphia (CHOP) found compelling preclinical evidence that a molecule called tumor necrosis factor alpha (TNFα), typically known for promoting inflammation, also plays a helpful role in recovery from anemia that is caused by ongoing immune disturbances.
Children’s Hospital of Philadelphia Researchers Discover Previously Hidden Brain Event During Electroconvulsive Therapy (ECT)
Researchers at Children’s Hospital of Philadelphia (CHOP) discovered a previously unrecognized brain event following electroconvulsive therapy (ECT), the most clinically effective treatment for severe, medication-resistant depression. The findings, which could provide additional insight into the biological mechanism of ECT, were recently reported in the journal Nature Communications.

Transformational $50 million gift will launch the Lurie Autism Institute at Children’s Hospital of Philadelphia and Penn Medicine
A $50 million gift to Children’s Hospital of Philadelphia (CHOP) and Penn Medicine will create an ambitious joint initiative called the Lurie Autism Institute to drive discoveries with transformative impact for those living with autism spectrum disorder (ASD). The gift, from the Lurie family, is the largest single donation to U.S. academic medical centers focused on autism research across the lifespan.
Children’s Hospital of Philadelphia Researchers Show Quality Improvement Initiative in the Emergency Department Improved Family Engagement Around Firearm Safety Resources
Researchers in the Center for Violence Prevention (CVP) at Children’s Hospital of Philadelphia (CHOP) embarked on a quality improvement (QI) initiative with behavioral health patients at CHOP’s Philadelphia and King of Prussia emergency departments with the goal of improving firearm safety conversations.

Pediatric Thyroid Center at Children’s Hospital of Philadelphia Performs 1,000th Thyroid Surgery
Children’s Hospital of Philadelphia (CHOP) reached a significant milestone — performing its 1,000th pediatric thyroid surgery in February. The Pediatric Thyroid Center at CHOP, which treats children and teens with thyroid disease, thyroid nodules, thyroid cancer, and other endocrine related disorders, is one of the busiest and most advanced U.S. centers of its kind.