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Research News from CHOP

Research News from CHOP

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The latest news from CHOP about our research.
News

Children’s Hospital of Philadelphia Study Shows Innovative “Food Pharmacy” Program Benefits Families Living with Food Insecurity

Researchers at Children’s Hospital of Philadelphia (CHOP) found that most patients and their families who reported experiencing food insecurity benefitted from consistent delivery of fresh produce and prepared healthy meals post-hospitalization. The study, recently published in Pediatrics, underscores the need for hospital systems to partner with community-based organizations to address food insecurity throughout the United States.

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Children’s Hospital of Philadelphia Researchers Announce Promising Results from First-of-its-Kind, Multicenter, Phase 1 Gene Therapy Trial for Danon Disease

Researchers at Children’s Hospital of Philadelphia (CHOP) announced encouraging results from the first ever gene therapy trial for Danon disease (DD), a rare, X-linked heart condition caused by a single gene mutation. The data on the results of the RP-A501 Phase 1 trial, presented at a late breaking session today at the American Heart Association Scientific Sessions 2024 in Chicago, were also published in the New England Journal of Medicine.

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New Research from Children’s Hospital of Philadelphia and St. Jude Poised to Transform Approach to Diagnosing and Treating Acute Leukemia in Children

Researchers at Children’s Hospital of Philadelphia (CHOP), St. Jude Children’s Research Hospital (St. Jude) and the Children’s Oncology Group (COG) today announced a significant paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia (T-ALL), an aggressive and high-risk form of cancer, to one frequently driven by genetic changes in non-coding portions of our DNA. The collaborative study, supported by the Gabriella Miller Kids First Pediatric Research Program (Kids First) and National Institutes of Health (NIH) Common Fund, was published today in the journal Nature.

News

Pioneering Single Cell Kidney Atlas Developed by Children’s Hospital of Philadelphia and Penn Medicine Researchers Sheds Light on Potential Treatments

Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania revealed the most extensive single cell atlas of the human kidney, capturing the complexity of healthy and diseased kidneys at an unprecedented level and predicting chronic kidney disease (CKD) progression earlier in its course. The findings were published today in the journal Nature Genetics.

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