Research News from CHOP


Children's Hospital of Philadelphia Announces Name of New Research Hub: The Morgan Center for Research and Innovation
Children’s Hospital of Philadelphia (CHOP) today announced that it has received a significant philanthropic gift from Mitchell L. Morgan, Dr. Hilarie L. Morgan and their family to name its state-of-the-art research facility currently under construction on the South Street bridge next to CHOP’s Roberts Center for Pediatric Research.
New Gene Therapy Model Offers Hope for X-Linked Sideroblastic Anemia Treatment
New model and vector may hold the keys to transforming the lives of XLSA patients.
Two CHOP Patients with an Inherited Blindness Successfully Treated with Gene Editing
The findings from the clinical trial were published in the New England Journal of Medicine.
Biomolecular Atlas for Bone Marrow to Offer Unprecedented Window into Blood Production
Researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania revealed a powerful new bone marrow atlas that will offer the public a first-of-its-kind visual passport into the spectrum of healthy and diseased blood production.
CHOP Researchers Identify Causal Genetic Variant Linked to Common Childhood Obesity
Target gene could serve as the basis of a future therapeutic intervention.
CHOP Study Finds Healthcare Providers Play Crucial Role in Guiding Autistic Adolescents and Their Families into Adulthood
The study identified obstacles like limited time during clinical visits, a lack of comprehensive resources, and insufficient notice from caregivers to prepare for discussions.
Researchers Publish Final Results of Key Clinical Trial for Gene Therapy for Sickle Cell Disease
In a landmark study, an international consortium led by researchers at CHOP published the final results of a key clinical trial of the gene therapy CASGEVY for the treatment of sickle cell disease.
CHOP Researchers Discover Underlying Biology Behind Fontan-Associated Liver Disease
Findings provide some of the first evidence of potential therapeutic targets for condition affecting thousands of patients with single ventricle congenital heart disease.
New Research Sheds Light on Long-Term Pulmonary Outcomes for Bronchopulmonary Dysplasia Patients
Researchers revealed new insights into the long-term effects of bronchopulmonary dysplasia (BPD), a chronic lung disease that primarily affects premature infants, on patient health.
CHOP Researchers Develop New Strategy for Assessing Natural History of Leukodystrophies
The methodology developed in this study could help guide clinical trial design for many rare diseases