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Infant with Congenital Diaphragmatic Hernia, Pre and Post-operative Care — Intraoperative Considerations for CDH Repair — Clinical Pathway: Inpatient and ICU

Infant with Congenital Diaphragmatic Hernia Clinical Pathway, Pre and Post-operative Care — Inpatient and ICU

Intraoperative Considerations for CDH Repair

Review Pediatric Anesthesiology: Congenital Diaphragmatic Hernia Repair Guidelines

Anesthesia Induction
  • Anesthesia to state when EHR record transitions to Anesthesia
  • Fentanyl and vecuronium
  • Add ketamine bolus or low-dose propofol infusion as indicated
  • Adjust ventilator rate to account for neuromuscular blocking agent
  • Draw arterial blood gas
  • Minimize FiO2 to allow the pulse oximeter to indicate changes in oxygenation
  • Increase FiO2 by 10% for surgery
  • FiO2 should not be increased further without discussion with neonatology as it is difficult to wean post-operatively
  • Antibiotics Prior to Incision
Maintenance/Intraoperative Considerations
  • Titrate anesthetics and vasoactive infusions as indicated
  • Communicate any hemodynamic changes to the surgeon
    • Hemodynamic compromise may occur during reduction of abdominal contents, as well as with liver manipulation and surgeons may need
      to pause
  • As abdominal wall is closed, communicate any changes in ventilation to
    the surgeon
    • Respiratory compromise may occur with abdominal wall closure
  • Blood gas every 30-60 mins
  • In the event of acute change in CO2, drop in heart rate or desaturations, ETT position and kinking should be considered
Thermoregulation
  • Goal ≥ 36
  • Forced air (i.e., Bair Hugger) warming is preferred over chemical mattress to allow warming throughout the duration of the procedure
  • Diaper should remain under baby to keep urine off body
  • Hat should be on to maintain normothermia
Anesthesia Considerations for Repair on ECMO
  • Due to absorption by the circuit, infant will likely require higher doses of opioids; consider addition of ketamine
  • Medications should be administered to the infant and not the circuit
  • Prepare for significant bleeding
    • pRBCs, FFP, and platelets at bedside
    • Discuss transfusion strategy with Neonatology Attending
    • Excess FFP may lead to clots in the circuit and result in need for
      circuit exchange
  • Circuit may “cut out” in setting of hypovolemia and/or liver manipulation
  • Amicar infusion per:

 

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