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Sodium and CEST MRI Study

Sodium and CEST MRI Study

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If you are interested in participating in the study or want to learn more, please get in touch. Contact us
This study is now recruiting. Learn more about enrolling here.

Description

This study is for children ages 6-18 years, both with and without brain tumors. The goal is to see if the two new types of magnetic resonance imaging (MRI) scans can help doctors diagnose brain tumors in children. An MRI is a machine that takes detailed pictures of the brain. The new types of MRI images in this study are still being tested and not yet approved by the FDA for finding brain tumors. Sodium MRI creates images of sodium distribution in the brain and is helpful for studying different brain conditions. CEST MRI creates images using water molecules and protons in the brain. Both methods are safe and do not require any injections, including sedatives or contrast agents.

Eligibility and criteria


IRB Number:
23-020779
Eligible age range:
6 years - 18 years
Clinical trial phase:
Pilot
Official title:
Quantitative Sodium Magnetic Resonance Imaging and Chemical Exchange Saturation Transfer (CEST) of Brain Tumors in Pediatric Patients

What to expect

The study requires at least one visit and is enrolling children aged 6-18 years, with and without brain tumors.

First visit: Participants will go through a screening process and give consent. Medical records will be reviewed, physical exam (vital signs), and a urine pregnancy test (for females) will be performed. All 30 participants will have a baseline MRI scan during this visit.

Second visit: A follow-up MRI scan will be scheduled about one month later for healthy participants.

Each MRI session will take about 90 minutes per visit.

Smiling CHOP patient holding shopping bag

We need families like you

Your time and participation make a difference in supporting the work of the Research Institute and children in our community. Learn more about opportunities to participate in our research.

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