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TACL-2020-003; IDEAL2 study

TACL-2020-003; IDEAL2 study

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If you are interested in participating in the study or want to learn more, please contact: Contact us
This study is now recruiting. Learn more about enrolling here.

Description

The purposes of this study is to examine efficacy of the IDEAL2 (Improving Diet and Exercise in ALL) caloricrestriction and activity intervention integrated into HR B-ALL induction to reduce incidence of end of induction (EOI) MRD ≥0.01%.

Eligibility and criteria


IRB Number:
22-020003
Eligible age range:
10 years - 26 years
Clinical trial phase:
Phase II
Official title:
A Phase 2 Randomized Trial of Caloric Restriction and Activity to Reduce Chemoresistance in B-Cell Acute Lymphoblastic Leukemia (IDEAL2)

What to expect

CHOP and the Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) consortium are conducting a study for children and young adults between the ages of 10 and 26 who are receiving induction therapy for NCI/Rome high-risk B-cell acute lymphoblastic leukemia (HR B-ALL). This study examines the efficacy of the IDEAL2 (Improving Diet and Exercise in ALL) caloric restriction and activity intervention integrated into HR B-ALL induction to reduce incidence of end of induction (EOI) MRD ≥0.01%. Subjects will be asked to come to CHOP for diet and exercise education, imaging scans, and questionnaires and will also wear a Fitbit activity monitor during the study. For more information about this study, including specific eligibility criteria, please visit clinicaltrials.gov and search for "NCT05082519" or visit the TACL website. To hear more about this and other available trails or get any questions answered please contact our Cancer Intake Specialist by phone at 267-426-0762 or email oncointake@chop.edu.
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