This study enrolls patients with cancer diagnoses who are expected to be hospitalized (inpatient) for at least 21 days. The purpose of this study is to determine whether a 21 day individualized massage therapy intervention, when compared to a control group, is associated with improved sleep and more robust circadian rhythms.

The purpose of this study is to see if a new investigational topical (applied to the skin) formulation of sirolimus, PTX-022 (the study drug), is safe and effective in treating participants with microcystic Lymphatic Malformations.