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Cardiac Center Publications

Cardiac Center Publications

International leaders in pediatric cardiac research

During the past three years, staff from the Cardiac Center have published 595 research articles, and received nearly 4,000 research citations. Here are some of our recent publications. 

April 2026

Anton-Martin P, Baxelbaum K, Vellore S, O'Neil E, Modem V, Thadani S. Body Mass Index and Survival in Children Receiving Extracorporeal Membrane Oxygenation. JAMA Netw Open. 2026 Apr 1;9(4): e266162. doi: 10.1001/jamanetworkopen.2026.6162. PMID: 42008270; PMCID: PMC13096981 **

Bainton J, Trachtenberg FL, Freemon D, Fremed MA, Klingman E, Lambert LM, McCrary AW, McCrindle BW, Rathge K, Sadhwani A, Segar DE, Shustak RJ, Sood E, Uzark K, Votava-Smith JK, Woodard Kline F, Mussatto KA. Stress, coping, protective factors, and quality of life in parents of infants with CHD: associations with state anxiety. Cardiol Young. 2026, Apr. 36(3):1-15. doi: 10.1017/S1047951126111809. PMID: 41940517; PMCID: PMC13107193.

Bakhshi S, Faisal NV, Naim MY, Gupta SK. Neurodevelopmental Outcomes After Cardiac Surgery for Congenital Heart Disease in India: A Narrative Review. Indian Heart J. 2026, Apr 20: S0019-4832(26)00074-X. doi: 10.1016/j.ihj.2026.04.012. PMID: 42019821

Bidzimou MK, Muralidharan P, Zhang Z, Raza D, Needs D, Sun B, Perelli RM, Moya- Mendez ME, Manivannan PKR, Hunanyan AS, Helfer A, Simmons CQ, George AL Jr, Bers DM, Bursac N, Mikati MA, Landstrom AP. D801N in ATP1A3-encoded Na/K-ATPase alpha 3 causes cardiac arrhythmogenesis through sodium-calcium exchangermediated calcium overload. JCI Insight. 2026, Apr. 11(7): e197721. doi: 10.1172/jci.insight.197721. PMID: 41948929

Biko DM. Letter from the Guest Editor: Imaging the Lymphatic and Venous Systems: Critical Components of the Circulation. Semin Roentgenol. 2026, Feb. 62:150981. doi: 10.1016/j.ro.2026.150981. PMID: 41713233

Biko DM, Giner C, Jones AL, Ramirez Suarez KI, Medina Perez M, Vaiyani D, Harris MA, Partington SL, Whitehead KK, Fogel MA. Effects of ACE inhibitor and afterload reduction in single ventricles following bidirectional Glenn. Open Heart. 2026, Mar. 13(1): e003678. doi: 10.1136/openhrt-2025-003678. PMID: 41876133; PMCID: PMC13034207

Blair J, Carratu K, Rintoul NE, Hedrick HL, Peranteau WH, Avitabile CM, McWalter K, Kruszka P, Krantz ID, Wild KT. Genomic Contributors to Congenital Diaphragmatic Hernia: Results of Exome Sequencing in 560 Probands and Cross Reference of Findings in an Independent Cohort. Am J Med Genet A. 2026, Apr. doi: 10.1002/ajmg.a.70145. PMID: 41943597

Catalano MA, Toubat O, Jacobs JP, Tchervenkov CI, Fraser CD 3rd, Fraser CD Jr, Bleiweis MS, Jacobs ML, Mavroudis C, St Louis JD, Finucane K, Gaynor JW, Mavroudis CD. Contemporary Use of Circulatory Arrest and Selective Antegrade Cerebral Perfusion During Neonatal Aortic Arch Surgery - International Survey. Ann Thorac Surg. 2026, Apr. S0003-4975(26)00329-2. doi: 10.1016/j.athoracsur.2026.03.064. PMID: 41985602

*Chaudhary AA, Jones AL, Artis AS, Tomlinson AZ, Drant S. A Second Look: Reanalysis of the Pediatric Heart Network Marfan Trial Data to Assess the Effects of Losartan and Atenolol on Disease Progression Using Aortic Cross-Sectional Area/Height. J Am Soc Echocardiogr. 2026, Mar. S0894-7317(26)00124-0. doi: 10.1016/j.echo.2026.03.004. PMID: 41819455

Froh EB, Brodecki D, Flood E, Lisanti AJ, Qiu S, Rizack L, Ruppel H, Schwarz J. Direct Annotation of Unstructured Clinical Progress Notes Describes Postpartum Healthcare Needs and Encounter Characteristics of Women Whose Newborns Are Immediately Hospitalized in Intensive Care. Adv Neonatal Care. 2026, Apr. doi: 10.1097/ANC.0000000000001353. PMID: 41955628

Hainstock MR, Fleming G, Kim D, Aboulhosn J, Levi D, Krasuski R, Sommer R, Torres AJ, Gray R, Kereiakes D, Leventhal A, Gillespie M, Szeto W, Zajarias A, Shahanavaz S, Steinberg ZL, Jones TK, Mahadevan VS, Moore P, Elmariah S, Shirali G, Li W, Babaliaros V, Lim DS; COMPASSION 3 Trial Executive Committee and Study Investigators. Five-Year Outcomes for Patients with RVOT Dysfunction Treated with the SAPIEN 3 Transcatheter Heart Valve: A Pooled Analysis from the COMPASSION S3 Trial. Circ Cardiovasc Interv. 2026 Mar 26: e016361. doi: 10.1161/CIRCINTERVENTIONS.125.016361. PMID: 41884901

Herrup EA, Shillingford AJ, Gaynor JW, Driscoll CFB, Hampton L, Zhang B, Baxelbaum K, Burnham N. Association of Parenting Stress in Early Childhood with Emotional Health and Resilience of Young Adults with Congenital Heart Disease. J Pediatr. 2026, Apr. 115110. doi: 10.1016/j.jpeds.2026.115110. PMID: 42002215 **

Jeewa A, Florez ID, Cuello-Garcia C, Alami N, Altamirano-Diaz L, Armstrong K, Ashkanase J, Cunningham C, Dhillon S, Dipchand A, Fazari L, Grosse-Wortmann L, Holinski P, Khoury M, Lin KY, Rossano J, Urschel S, Zahavich L, Kantor PF, Conway J, Atallah J, Bucholz H, Chant-Gambacourt C, Dallaire F, Dancea A, Fournier A, George K, Greenway S, Human DG, Lougheed J, Mejilla A, Price JF, Roche SL, Ryerson L. Canadian Cardiovascular Society/Canadian Pediatric Cardiology Association Focused Guidelines on Acute Heart Failure in Children. Can J Cardiol. 2026, Apr. 42(4):626-646. doi: 10.1016/j.cjca.2025.12.035. PMID: 41951283

Glenn TM, Kasparian NA, Amdani S, Renaud D, DiMaria MV, Teh J, Leone DM, Mahendran AK, Pike NA, Dolgner SJ, Cheng AL, Rathod RH, Vaikunth SS, Veeram Reddy SR, Vanam R, Theobald J, Schumacher KR, Hummel SA, Conway J, Goldberg DJ, Zakaria D, Clauss SB, Suthar D, Jacobsen RM, Morell EM, Dykes JC, Weingarten AJ, Bhat DP, Reinking BE, Alsaied T, Lannon C, Allen KY, Anderson JB, Patterson LB, Brown DW, James R, Rychik J, Opotowsky AR; SV-ONE Investigators. The Fontan Outcomes Network: Findings After 2 Years and 1121 Participants. Circulation. 2026, Apr 21;153(16):1182- 1195. doi: 10.1161/CIRCULATIONAHA.125.078152. PMID: 41878814

Klein WM, Biko DM, Gerwins P, Petit P. Imaging of complex lymphatic anomalies in children. Pediatr Radiol. 2026, Apr. doi: 10.1007/s00247-026-06608-z. PMID: 42024244

Ladha HM, Wang JC, Li Y, Christopher AB, Kreutzer J, Krishnamurthy R, Raimondi F, Robinson JD, Loke YH, Olivieri LJ, Fogel MA, Ceschin R, Rathod RH, Alsaied T; FORCE Investigators. Measuring Atrioventricular Valve Regurgitation Using 4D Flow Cardiovascular Magnetic Resonance Post-Fontan. Pediatr Cardiol. 2026, Apr. doi: 10.1007/s00246-026-04243-x. PMID: 41945116

*Naeem M, Rogers LS, O'Byrne ML, Giglia TM, Callahan R. Transcatheter Management of Native Aortic Root Thrombus After Fontan Palliation in a Pediatric Patient With COVID-19. JACC Case Rep. 2026, Apr. 107532. doi: 10.1016/j.jaccas.2026.107532. PMID: 42017856

O'Byrne ML, Glatz AC, Gupta M, Tang J, Smith CL, Dori Y, Rome JJ, Gillespie MJ, Callahan R. Technical Success and Adverse Events Associated with Percutaneous Carotid Artery Access for Transcatheter Procedures in Infants. Catheter Cardiovasc Interv. 2026, Apr. doi: 10.1002/ccd.70601. PMID: 41930471

Pettit AN, Nitsche L, Toomey N, Harris MA, Mavroudis CD. Scimitar syndrome and single ventricle physiology: evolving strategies and the role of bridge-totransplant therapy. Cardiol Young. 2026, Apr. 6:1-3. doi: 10.1017/S1047951125111025. PMID: 41940512

Przybylski R, Norrish G, Claggett B, Ashley EA, Bhole V, Day SM, Delle Donne G, Fernandez A, Girolami F, Gray B, Helms AS, Ingles J, Kubus P, Lakdawala NK, Lampert RJ, Lin KY, Michels M, Miller E, Olivotto I, Owens A, Parikh VN, Passantino S, Radulescu CR, Rossano J, Russell MW, Ryan TD, Saberi S, Spentzou G, Stendahl JC, Ware JS, Weintraub RG, Ziolkowska L, Zwetsloot PP, Kaski JP, Ho CY, Abrams DJ; SHaRe and IPHCC Investigators. The Natural History of Massive Left Ventricular Hypertrophy in Pediatric Hypertrophic Cardiomyopathy: A Multiregistry Analysis. Circulation. 2026, Apr. doi: 10.1161/CIRCULATIONAHA.126.078843. PMID: 41993018

Pullamsetti SS, Vanderpool RR, de Man F, de Jesus Perez VA, Hemnes AR, Mukherjee M, Mercer-Rosa L, Spiekerkoetter E, Tello K, Bonnet S; Council on Cardiopulmonary, Critical Care, Perioperative, and Resuscitation; Council on Clinical Cardiology; and Council on Cardiovascular Surgery and Anesthesia. Advanced Molecular, Metabolic, and Imaging Approaches to Characterizing Right Ventricular Failure: A Scientific Statement from the American Heart Association. Circulation. 2026, Apr. doi: 10.1161/CIR.0000000000001422. PMID: 41924886

Ranieri NR, Forti RM, Baker WB, Nicolson SC, Lynch JM. Monitoring Cerebral Oxygenation During Neonatal Cardiac Surgery: Limitations of Conventional NIRS. Paediatr Anaesth. 2026, Apr. doi: 10.1002/pan.70183. PMID: 41960715

Rouzbehani OM, Stephens S, Werbner B, Szulik MW, Sun B, Hua M, Watanabe S, Leonelli A, Goodman M, Bia R, Davey CF, Golkowski MG, Franklin S, Landstrom AP, Boudina S. Perm1 Gene Therapy Mitigates PRDM16-Associated Cardiomyopathy. bioRxiv [Preprint]. 2026, Apr. 2026.04.13.718330. doi: 10.64898/2026.04.13.718330. PMID: 42039588; PMCID: PMC13104965

Ruppe M, DeWitt A, Schumacher KR, Jacobs JP, Algaze CA, Smith A, Akins R, Mikesell K, Zhang W, Austin E, Lasa JJ. Diaphragm dysfunction following congenital heart surgery: Epidemiology and outcomes. J Thorac Cardiovasc Surg. 2026, Feb. S0022- 5223(26)00181-9. doi: 10.1016/j.jtcvs.2026.02.024. PMID: 41765325

Rychik J. Reply: Fibrosis Is Inevitable, but Heterogeneous: Time-Dependent and Biochemical Modifiers of Liver Injury After Fontan Completion. JACC Adv. 2026, Apr. 5(5):102762. doi: 10.1016/j.jacadv.2026.102762. PMID: 42025259; PMCID: PMC13126479

Solly HH, Lisanti AJ, Kamen A, Spatz DL. Influence of Hospital Policy and Nurse Competency on Rates of Skin-to-Skin Contact in Neonates. Nurs Womens Health. 2026, Mar. S1751-4851(26)00035-8. doi: 10.1016/j.nwh.2025.11.005. PMID: 41912051

Torres AJ, Dimas VV, Shahanavaz S, Balzer D, Morgan G, Lim DS, Armstrong AK, Berman D, Babaliaros V, Kim D, Gillespie MJ, Sommer R, Aboulhosn J, Jones TK, Mahadevan VS, Stapleton G, Ma Y, Shirali G, Parthiban A, Blanke P, Leipsic J, Zahn E. Transcatheter Pulmonary Valve Implantation With the Alterra Adaptive Prestent and SAPIEN 3 Transcatheter Heart Valve: 3-Year Pooled Outcomes of the ALTERRA Trials. Circ Cardiovasc Interv. 2026 Apr;19(4): e015873. doi: 10.1161/CIRCINTERVENTIONS.125.015873. PMID: 41657206

Vaiyani D, Gupta M, DeWitt AG, Shustak R, Favilla E, Pinto E, Biroc L, Yowell M, Dori Y, Smith CL. Lymphatic Complications in Congenital Heart Disease. Semin Roentgenol. 2026, Apr. 62:150983. doi: 10.1016/j.ro.2026.150983. PMID: 41985333

Vissing CR, Axelsson Raja A, Helms AS, Saberi S, Owens AT, Rossano JW, Abrams DJ, Ingles J, Gray B, Lampert R, Stendahl JC, Lakdawala NK, Ware JS, Parikh VN, Michels M, Crotti L, Ryan TD, Olivotto I, Day SM, Bundgaard H, Claggett BL, Ho CY. Differences in Disease Trajectory, Comorbidities, and Mortality in Sarcomeric and Nonsarcomeric Hypertrophic Cardiomyopathy. Circulation. 2026, Apr. 153(15):1104-1116. doi: 10.1161/CIRCULATIONAHA.125.076036. PMID: 41800474

March 2026

Chauhan A, El Omeiri S, Prodigios J, Pogoriler J, Corcoran A, White AM, Biko DM, Otero HJ, Piccione J, Rapp JB. Endobronchial Lesions in Children: Radiologic, Bronchoscopic, and Pathologic Correlation. Radiographics. 2026 Mar;46(3): e250115. doi: 10.1148/rg.250115. PMID: 41678367

El-Assaad I, Hammond B, Clark BC, Tanel RE, Dubin AM, Law I, Marino BS, Cassedy A, Saarel E, Shah MJ, Kannankeril PJ, Dasgupta S, Mah D. Shocking Practices of Pediatric Electrophysiologists: Contemporary Defibrillation Testing Data from a Multicenter National CIED Registry. Circ Arrhythm Electrophysiol. 2026, Mar. e014288. doi: 10.1161/CIRCEP.125.014288. PMID: 41766533

Glenn TM, Kasparian NA, Amdani S, Renaud D, DiMaria MV, Teh J, Leone DM, Mahendran AK, Pike NA, Dolgner SJ, Cheng AL, Rathod RH, Vaikunth SS, Veeram Reddy SR, Vanam R, Theobald J, Schumacher KR, Hummel SA, Conway J, Goldberg DJ, Zakaria D, Clauss SB, Suthar D, Jacobsen RM, Morell EM, Dykes JC, Weingarten AJ, Bhat DP, Reinking BE, Alsaied T, Lannon C, Allen KY, Anderson JB, Patterson LB, Brown DW, James R, Rychik J, Opotowsky AR; SV-ONE Investigators. The Fontan Outcomes Network: Findings After 2 Years and 1121 Participants. Circulation. 2026, Mar. doi: 10.1161/CIRCULATIONAHA.125.078152. PMID: 41878814

Hill KD, Kang L, Wang Q, Newburger JW, Gaynor JW, Burns KM, Williams R, Trachtenberg F, McCrindle BW, Graham EM, Pizarro C, Ashfaq A, Souza A, Kuo JA, Ilardi D, Schumacher KR, Hong H, Goldberg CS, Pediatric Heart Network Investigators. Single-Ventricle Disease: Long-Term Outcomes and Global Morbidity in the Single Ventricle Reconstruction Trial. J Am Coll Cardiol. 2026, Mar 4: S0735-1097(26)00222-6. doi: 10.1016/j.jacc.2026.01.049. PMID: 41811273; PMCID: PMC12979933

Iacovella J, Vaiyani D, Pressley S, Lasso A, Sulentic AM, Cianciulli AR, Koluda A, Daemer M, Fogel MA, Whitehead KK, Jolley MA. Rapid Visualization of Valves and Myocardium Using Volume Rendering of 3D Cardiac MRI, 4D Cine, and 4D Flow Images. Radiol Cardiothorac Imaging. 2026, Feb;8(1): e250129. doi: 10.1148/ryct.250129. PMID: 41677452; PMCID: PMC12949417

Levine D, Camillo C, Castillero E, Bektik E, Kosuri Y, Campbell A, Karcher C, Krieger A, Pei L, Peng T, Zeak N, Faridmoayer E, Oyama MA, Grau JB, Levy RJ, Ferrari G. Serotonin transporter downregulation is associated with aortic stenosis, and early profibrotic remodeling is mitigated by pharmacological inhibition of HTR2B receptor. Front Cardiovasc Med. 2026, Feb. 13:1729078. doi: 10.3389/fcvm.2026.1729078. PMID:  41768577; PMCID: PMC12935953

Lin JR, Miller D, Luong D, Nelson T, Crowley TB, Tran OT, Thiruvahindrapuram B, Hajianpour A, Campbell L, Busa T, Heine-Suñer D, García-Miñaúr S, Fernández L, Murphy KC, Murphy D, Hawula W, Angkustsiri K, Shashi V, Schoch K, Bearden CE, Tomita Mitchell A, Mitchell ME, Carmel M, Weizman A, Michaelovsky E, Gothelf D, van den Bree MBM, Owen MJ, Vorstman JAS, Boot E, Vingerhoets C, van Amelsvoort T, Swillen A, Breckpot J, Vermeesch JR, Devriendt K, Schneider M, Eliez S, Digilio MC, Unolt M, Putotto C, Marino B, Pontillo M, Armando M, Vicari S, Repetto GM, Kates WR, Shprintzen RJ, Gur RE, Zackai EH, Goldmuntz E, Wang T, Raj S, Emanuel BS, McDonald-McGinn DM, Scherer SC, Bassett AS, Zhang ZD, Morrow BE. Deletion size and background genetic variation shape congenital heart disease phenotypes in 3,016 individuals with 22q11.2 deletion syndrome. medRxiv [Preprint]. 2026, Mar. 2026.02.23.26346918. doi: 10.64898/2026.02.23.26346918. PMID: 41891037; PMCID: PMC13015682

Lynch A, Shezad MF, Kroslowitz B, Jeewa A, Dykes J, Law S, O'Connor M, Butts R, Joong A, Lorts A, Amdani S, VanderPluym C. Multicenter Registry Analysis of Bivalirudin for Primary Anticoagulation in Pediatric HeartMate 3 Recipients: ACTION Analysis. ASAIO J. 2026 Mar 12. doi: 10.1097/MAT.0000000000002692. PMID: 41813628

Nasr VG, Kuntz M, Chin V, Deutsch N, Faraoni D, Miller-Hance WC, Nicolson SC, Richtsfeld M, Staffa SJ. Intraoperative Cardiac Events in Pediatric Patients with Congenital Heart Disease Undergoing Noncardiac Procedures: Analysis of a Large Multicenter Registry. Anesthesiology. 2026, Feb.144(2):314-324. doi: 10.1097/ALN.0000000000005783. PMID: 41043169; PMCID: PMC12777584

Nelson JE, Petit CJ, Goldstein BH, Glatz AC, Zhang Y, McCracken CE, Mascio CE, Weber R, Nicholson GT, Zampi JD, Romano JC, O'Byrne ML, Law MA, Shahanavaz S, Meadows JJ, Qureshi AM, Ligon RA; Additional Authors from the Congenital Cardiac Research Collaborative see Appendix; Lee TM. Genetic Syndromes Do Not Affect Survival but Increase Morbidity in Neonates with Symptomatic Tetralogy of Fallot. J Pediatr. 2026, Mar. 115058. doi: 10.1016/j.jpeds.2026.115058. PMID: 41812746

Raghuveer G, Coffee M, Dahdah N, Harahsheh AS, Dionne A, Portman MA, Nowlen TT, Pagano JJ, Gunsaulus M, Wehrmann M, Tierney S, Fabi M, Lee S, Szmuszkovicz J, Lang SM, Thacker D, Elias MD, Burns JC, Yamazaki-Nakashimada MA, C K, Harris, Jain SS, Butris N, Manlhiot C, McCrindle BW; International Kawasaki Disease Registry (IKDR). Did the COVID-19 pandemic change the Kawasaki disease phenotype? Observations from the International Kawasaki Disease Registry. Pediatr Cardiol. 2026, Feb 21. doi: 10.1007/s00246-026-04201-7. PMID: 41721872

Rossano JW, Canter C, Wolf CM, Papez A, Gambra M, Bryant RM, Alejos J, McCulloch M, Sarquella Brugada G, Bock MJ, Jeewa A, Pearce FB, Desai MY, Favatella N, Javidialsaadi A, Phung V, Rano T, Zhu L, Dyme JL, Mital S; SCOUT-HCM Investigators. Mavacamten in Adolescents with Obstructive Hypertrophic Cardiomyopathy. N Engl J Med. 2026, Mar. doi: 10.1056/NEJMoa2601103. PMID: 41910394

*Russell WW, Rossano J, Paridon S, Stephens P, Brothers JA, Srinivasan C, Edelson J. A High-Level Athlete with Tachycardia-Induced Cardiomyopathy: A Can't Miss Diagnosis. JACC Case Rep. 2026, Mar. 31(12):107155. doi: 10.1016/j.jaccas.2026.107155. PMID: 41906563

*Teresczuk ME, Rossano JW. Pediatric heart transplantation: We've come a long way but there is still a long way to go. J Heart Lung Transplant. 2026, Mar. 45(3):492-493. doi: 10.1016/j.healun.2025.11.009. PMID: 41285286

Vissing CR, Axelsson Raja A, Helms AS, Saberi S, Owens AT, Rossano JW, Abrams DJ, Ingles J, Gray B, Lampert R, Stendahl JC, Lakdawala NK, Ware JS, Parikh VN, Michels M, Crotti L, Ryan TD, Olivotto I, Day SM, Bundgaard H, Claggett BL, Ho CY. Differences in Disease Trajectory, Comorbidities, and Mortality in Sarcomeric and Nonsarcomeric Hypertrophic Cardiomyopathy. Circulation. 2026 Mar 9. doi: 10.1161/CIRCULATIONAHA.125.076036. PMID: 41800474

Wen H, Liberti DC, Chandrasekaran P, Parveen S, Quansah KK, Kim M, Lange AN, Marquis AT, Michki SN, Jin A, Lu M, Fasan AA, Suresh S, Shirazi SP, Young LR, Sucre JM, Basil MC, Jain R, Frank DB. BRD4 promotes endodermal cell fate during mammalian lung development. JCI Insight. 2026, Feb. 11(5): e194683. doi: 10.1172/jci.insight.194683. PMID: 41632526

February 2026

Anton-Martin P, Coalter C, DeAvilla K, Ray M, W Kozyak B, Briceno-Medina M, Rayburn M. Clopidogrel Dosing Scheme in Pediatric Cardiac Patients 0-24 Months Old Using P2Y12 Reaction Unit Monitoring. J Pediatr Pharmacol Ther. 2026, Feb. 31(1):30-36. doi: 10.5683/JPPT-25-00024. PMID: 41675490; PMCID: PMC12888990

Asher M, O'Byrne M, Callahan R, Mavroudis CD. Patients as a Limited Resource? Ethical Dilemmas in Pediatric Pulmonary Vein Stenosis. J Clin Ethics. 2026, Spring. 37(1):23-33. doi: 10.1086/739011. PMID: 41698339

Dalby S, Luna M, *Faraji E, Lemoine T, Daily J. Structural Inequities in Pediatric Versus Adult Interventional Cardiology: A Lifetime Earnings and Productivity Analysis. JSCAI. 2026, Feb. doi: 10.1016/j.jscai.2025.104194

Hussain MA, He S, Adams HR, Anagnoustou E, Bellinger DC, Brueckner M, Chung WK, Cleveland J, Gelb BD, Goldmuntz E, Hagler DJ Jr, Huang H, McQuillen P, Miller TA, Norris-Brilliant A, Porter GA Jr, Thomas N, Tivarus ME, Xu D, Shen Y, Newburger JW, Grant PE, Morton SU, Ou Y. Machine learning to infer neurocognitive testing scores among adolescents and young adults with congenital heart disease. Commun Med (Lond). 2026, Feb. doi: 10.1038/s43856-026-01417-9. PMID: 41651962

Kim YY, Ganger D, Tomlinson AZ, Farkas IZ, Rychik J, Imperial J, McRae MP, Everson GT, Hoteit MA. Hepatic cholate clearance as assessed by HepQuant-SHUNT is associated with clinical outcomes in individuals with Fontan circulation. Int J Cardiol Congenit Heart Dis. 2026, Jan. 23:100654. doi: 10.1016/j.ijcchd.2026.100654. PMID: 41695267; PMCID: PMC12906153 **

Kim SW, Parfenov M, Rodriguez-Murillo L, Conner DA, Sharma A, Peter I, Xiao F, Layton O, Tai A, Ward T, Wasson LK, Gorham JM, Mazaika E, Lagomarsino VN, Young-Pearse TL, Goldmuntz E, Wakimoto H, Agopian AJ, McKean DM, DePalma SR, Pu WT, Seidman CE, Gelb BD, Seidman JG; PCGC Investigators. ROBO2 Variants Associated with Atrial Septal Defect Define a Novel Regulatory Element. Circ Genom Precis Med. 2026, Feb. e004918. doi: 10.1161/CIRCGEN.124.004918. PMID: 41693552

Kobayashi Y, Maeda K. Commentary: On the horizon: Intracardiac resection. J Thorac Cardiovasc Surg. 2026, Jan. S0022-5223(26)00020-6. doi: 10.1016/j.jtcvs.2026.01.008. PMID: 41565066

Lintner-Rivera M, Maxson IN, Al-Subu AM, Bhargava V, Chandnani HK, Chong G, Conlon TW, Davis JJ, Flores S, Ginsburg S, Gutierrez P, Haileselassie B, Kozyak BW, Li B, MacDonald JM, Nishisaki A, Ramírez MM, Tripathi S, Wenger JL, Fastag-Guttman E, Scully PT, Thammasitboon S, Su E; Pediatric Research Collaborative on Critical Ultrasound (PeRCCUS) a subgroup of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Research Network. Proposing Entrustable Professional Activities for Pediatric Critical Care Ultrasound: A Modified Delphi Consensus Approach. Pediatr Crit Care Med. 2026, Feb. 27(2):235-243. doi: 10.1097/PCC.0000000000003886. PMID: 41642061

Musante L, Janos P, Pianigiani G, Cappelli S, Longo A, Alves C, Schwaibold EM, Wagner M, Costain G, Fridriksdottir R, Stefansson K, Sulem P, Lichtenbelt KD, van Binsbergen E, van Jaarsveld RH, Brusco A, Pavinato L, Biamino E, Spano A, Hildebrandt CC, Chan YM, Groopman E, Berkenstadt M, Koboldt D, Williamson R, Brunner HG, Vissers LE, Torring PM, Hao Q, Gelb BD, Goldmuntz E, Reed K, Bedoukian EC, Vecchio D, Salzano E, Piccione M, Zanus C, Mio C, Eichler EE, Wang T, Patterson WG, Butler KM, Piotrowski M, Mercier S, Cogné B, Wentzensen IM, Buratti E, Magistrato A, Faletra F. A novel spliceosomopathy caused by de novo SF3B3 variants. Genome Med. 2026, Feb. doi: 10.1186/s13073-026-01610-4. PMID: 41709284

Patregnani JT, Ankola AA, Kim JS, Downey L, Klugman D, Baltagi S, Linder J, Banerjee M, Zhang W, Mikesell K, Schumacher K, Giglia T, Werho DK. Risk Factors Associated with Central Venous Catheter-Associated Deep Vein Thrombosis After Pediatric Congenital Heart Surgery: An Analysis of the Pediatric Cardiac Critical Care Consortium Registry. World J Pediatr Congenit Heart Surg. 2026, Feb. 21501351251386697. doi: 10.1177/21501351251386697. PMID: 41642867

Penk JS, Bhargava V, Chandnani H, Chong G, Conlon T, DeSanti RL, Diddle JW, Floh A, Flores S, Hsieh A, Kantor D, Kaplan D, Kozyak B, Li B, Lumpkin C, MacDonald J, Maxson I, Nishisaki A, Patel MD, Riggs BJ, Rivera ML, Martinez M, Mills M, Ramírez M, Tripathi S, Veten A, Vijayakumar N, Wenger J, Werho DK, Su E, Al-Subu A; Pediatric Research Collaborative on Critical Ultrasound (PeRCCUS), Subgroup of Pediatric Acute Lung Injury and Sepsis Investigators (PALISI). Good Practice Concepts in Pediatric Critical Care Point-of-Care Ultrasound: A Modified Delphi Consensus Initiative. Pediatr Crit Care Med. 2026, Feb. 27(2):228-234. doi: 10.1097/PCC.0000000000003881. PMID: 41642060

Shah MJ, Weinreb SJ. Top stories: Pediatric CIEDs. Heart Rhythm. 2026, Jan. 23(1):223- 224. doi: 10.1016/j.hrthm.2025.08.043. PMID: 41485809

Van Bulck L, Goossens E, Kovacs AH, Luyckx K, Ladak LA, Leye M, Van De Bruaene A, Leong MC, Kaneva A, Pavão RB, Araujo JJ, Sasikumar N, Gabriel H, Goshu DY, Lu CW, Enomoto J, Areias ME, Kosmidis D, Coats L, Valente AM, Moon JR, Ladouceur M, Thomet C, Jackson JL, Sandberg C, Callus E, Kim YY, Lykkeberg B, Alday L, Bredy C, Saidi A, Reyes FB, Menahem S, de Hosson M, Mandelenakis Z, Christersson C, Zaidi A, Johansson B, Andresen B, Ambassa JC, Mattsson E, Constantine A, Amedro P, van Melle JP, Cedars A, Ortiz L, Demir F, Khairy P, Windram J, Bouchardy J, Caruana M, Jameson SM, Mahadevan VS, McGrath LB, Mwita JC, Moons P; APPROACH-IS II consortium, International Society for Adults Congenital Heart Disease (ISACHD). Advance Care Planning in Adults with Congenital Heart Diseases: Current Practices, Preferences, and Needs of 8,281 Adults From 32 Countries. Can J Cardiol. 2026, Jan. S0828-282X (25)01607-1. doi: 10.1016/j.cjca.2025.12.039. PMID: 41519299

Van Bulck L, Goossens E, Kovacs AH, Luyckx K, Ladak LA, Leye M, Van De Bruaene A, Leong MC, Kaneva A, Pavão RB, Araujo JJ, Sasikumar N, Gabriel H, Goshu DY, Lu CW, Enomoto J, Areias ME, Kosmidis D, Coats L, Valente AM, Moon JR, Ladouceur M, Thomet C, Jackson JL, Sandberg C, Callus E, Kim YY, Lykkeberg B, Alday L, Bredy C, Saidi A, Reyes FB, Menahem S, de Hosson M, Mandelenakis Z, Christersson C, Zaidi A, Johansson B, Andresen B, Ambassa JC, Mattsson E, Constantine A, Amedro P, van Melle JP, Cedars A, Ortiz L, Demir F, Khairy P, Windram J, Bouchardy J, Caruana M, Jameson SM, Mahadevan VS, McGrath LB, Mwita JC, Moons P; APPROACH-IS II consortium, International Society for Adults Congenital Heart Disease (ISACHD). Advance Care Planning in Adults with Congenital Heart Diseases: Current Practices, Preferences, and Needs of 8,281 Adults From 32 Countries. Can J Cardiol. 2026, Jan. S0828-282X (25)01607-1. doi: 10.1016/j.cjca.2025.12.039. PMID: 41519299

January 2026

Avitabile CM, Jones AL, Faig W, Wild KT, Tam V, Diaz EM, Gebb JS, Khalek N, Gaynor JW, Hedrick HL. Maternal neighborhood characteristics are associated with left heart disease, extracorporeal membrane oxygenation, and mortality in congenital diaphragmatic hernia. Neonatology. 2026 Jan. doi: 10.1159/000550647. PMID: 41615871.

Black RT, Maas SA, Wu W, Maheshwari J, Kolev T, Weiss JA, Jolley MA. An open-source computational framework for immersed fluid-structure interaction modeling using FEBio and MFEM. ArXiv [Preprint]. 2026 Jan 13. PMID: 41647235.

Cardoso Cavalcante R, Brunetti M, Hsiung JC, Sanderlin R, Baxelbaum K, Vellore S, Anton-Martin P. Extracorporeal Membrane Oxygenation Discontinuation Due to Resource Limitations. ASAIO J. 2026 Jan. doi: 10.1097/MAT.0000000000002652. PMID: 41508327.

Crossley GH, Sanders P, Hansky B, De Filippo P, Shah MJ, Khelae SK, Richardson TD, Philippon F, Zakaib JS, Geelen T, Arias K, Maus B, Mason PK. Safety and Efficacy of the Novel OmniaSecure Defibrillation Lead Through Long-Term Follow-Up: Final Results from the LEADR Trial. Circ Arrhythm Electrophysiol. 2026 Jan. doi: 10.1161/CIRCEP.125.014424. PMID: 41222500.

de Ferranti SD, Teng JE, Arslanian SA, Atz AM, Brothers JA, Cartoski MJ, Freemon DR, Magge SN, Mahle WT, Mietus-Snyder M, Peterson A, Raghuveer G, Russell MW, Shah AS, Sponseller CA, Stylianou M, Trachtenberg FL, Urbina EM, Ware AL, Zachariah J, Zadokar VV, McCrindle BW. A multicenter trial to test pitavastatin calcium in youth with combined dyslipidemia of obesity: Design, implementation, challenges, and responses. Am Heart J. 2025 Dec;294:107327. doi: 10.1016/j.ahj.2025.107327. PMID: 41407061.

Edwards JJ, Edelson JB, Rossano JW. RNA-Based Therapies for Treating Monogenic Cardiomyopathies. Can J Cardiol. 2026 Jan. doi: 10.1016/j.cjca.2025.12.040. PMID: 41512965.

Fabi M, Harahsheh AS, Raghuveer G, Wehrmann M, Portman MA, Dahdah N, Sabati AA, Misra N, Yamazaki-Nakashimada MA, Khoury M, Jain SS, Sundaram B, Orr W, Szmuszkovicz J, Dionne A, Thacker D, Prasad D, Sutton N, Hicar MD, Harris TH, Elganzoury M, Knutson S, Cruz J, Elias MD, Tierney S, Mondal T, Dallaire F, Lee S, Grcic M, Barnes B, Garrido LM, Manlhiot C, Farid P, McCrindle BW. Gastrointestinal Symptoms in Kawasaki Disease and Multisystem Inflammatory Syndrome in Children. Pediatr Cardiol. 2026 Jan. doi: 10.1007/s00246-025-04097-9. PMID: 41579198.

Hakimi M, Mondal A, Ampah SB, Tomlinson AZ, O'Byrne ML, Janson C. Admission rates for pediatric supraventricular tachycardia are affected by primary insurance payor: An analysis of the NEDS database. Am Heart J. 2026 Jan. doi: 10.1016/j.ahj.2026.107357. PMID: 41605361.

Jackson JL, Wolfe KR, Gaynor JW, Suarez L, Umfleet L, Puder R, Brown K, Cassidy AR, Gurvitz M. Prioritizing Neurocognitive and Psychosocial Outcomes in Adults with Congenital Heart Disease: A Consensus Statement from the Adults with Congenital Heart Disease/Neuro 2024 Conference. J Am Heart Assoc. 2026 Jan;15(2):e042672. doi: 10.1161/JAHA.125.042672. PMID: 41553047.

Kramarenko DR, Haydarlou P, Powell GJ, Rämö JT, Janan R, Prince C, Zimmerman DS, et al. Leveraging the shared and opposing genetic mechanisms in the heritable cardiomyopathies. Res Sq [Preprint]. 2026 Jan. doi: 10.21203/rs.3.rs-8346032/v1. PMID: 41646289.

Maheshwari J, Wu W, Zelonis CN, Maas SA, Sunderland K, Barak-Corren Y, Ching S, Sabin P, Lasso A, Gillespie MJ, Weiss JA, Jolley MA. Effect of Right Ventricular Outflow Tract Material Properties on Simulated Transcatheter Pulmonary Placement. ArXiv [Preprint]. 2026 Jan 8. PMID: 41542163.

Marzolini N, Brysgel TV, Rahman RJ, Essien EO, Nwe SY, Wu J, Majumder A, Patel MN, Tiwari S, Espy CL, Dong F, Santos-De León SA, Shah A, Shuvaev VV, Hood ED, Chase LS, Weissman D, Katzen JB, Frank DB, Bennett ML, Marcos-Contreras OA, Myerson JW, Muzykantov VR, Reyes-Esteves S, Brenner JS. Targeting DNA-LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity. Adv Sci (Weinh). 2026 Jan. doi: 10.1002/advs.202515480. PMID: 41556437.

McMahon CJ, Penny D, Rossano J. The Triple Gift: Kindness, Compassion, and Humility in Pediatric Cardiology. Pediatr Cardiol. 2026 Jan. PMID: 41543537.

McMahon CJ, Ryan C, Vacher CS, Rossano J, Penny DJ. Embedding Compassion and Communication Frameworks in Pediatric Cardiology. Pediatr Cardiol. 2026 Jan. PMID: 41533089.

Montgomery CM, Rastogi R, Dewitt A, Kozyak BW, Ha L, Weiss F, Eichner JR, Ahmed H, Tang J, Maeda K, Chaudhary AA, Lane-Fall M, Rosenthal T, Gardner MM, Li ZN, Rossano J, O'Connor MJ, Wittlieb-Weber C, Edelson JB. Implementing a Programmatic Approach to Identify and Promote Ventricular Recovery in Pediatric Patients Supported With Ventricular Assist Devices. J Am Heart Assoc. 2026 Feb;15(3):e045453. PMID: 41568561.

Pouch AM, Dong JN, Litt HI, Cannon BJ, Freas M, Ferrari V, Gleason TG, Jolley MA, Yushkevich N, Nunez J, Hao J, Guo Z, Goldfinger S, Kelly J, Bavaria JE, Desai ND. CT-based visualization of aortic valve morphology: from 3D energy-integrating CT to 4D photon counting CT. Front Cardiovasc Med. 2026 Jan. PMID: 41602341.

Rwebembera J, Sable C, Grobler AC, Pulle J, Scheel A, Mucunguzi A, Spaziani AM, Engelman D, Carapetis J, Karthikeyan G, Lwabi P, Zühlke L, Nunes MCP, Wilson N, Mocumbi AO, Ndagire E, Okwera CM, Akullo S, Etyang J, Rudkin A, Sarnacki R, Nakitto M, Atim B, Okello E, Steer A, Beaton A. With Antibiotic Prophylaxis, Mild Rheumatic Heart Disease Rarely Progresses Over 5 Years. J Am Heart Assoc. 2026 Jan. PMID: 41532533.

Rosenthal DN, Amodeo A, Butterfield RJ, Butts R, Chrzanowski S, Cripe L, Day J, Davies R, Duong T, Evers P, Gambetta K, Harris R, Hayes E, Kaufman B, Lorts A, Mack G, Mackenzie SJ, Mammen P, Markham L, McAlister J, McDonald C, Nakano SJ, Nandi D, Navaratnam M, Nelson S, Parent JJ, Piccoli C, Richmond M, Rocha C, Sawnani H, Schrader R, Shell R, Shih R, Shugh S, Smart T, Soslow J, Spinner J, Taivassalo T, Tunugtla H, VanderPluym C, Veerapandiyan A, Villa C, Wittlieb-Weber C, Zafarullah M, Hollander S. Heart Transplantation and Ventricular Assist Device in Duchenne Muscular Dystrophy: A New Era. Pediatr Transplant. 2026 Jan. PMID: 41424087.

Shah M, Blom NA. Slow Conducting Anatomical Isthmus and VT Inducibility in Repaired Tetralogy of Fallot: It Takes More Than 2 to Tango. JACC Clin Electrophysiol. 2026 Jan. PMID: 41348076.

Shah MJ, Weinreb SJ. Top stories: Pediatric CIEDs. Heart Rhythm. 2026 Jan. PMID: 4148580.

Srinivasan A, Smith CL, Gupta M, Laje P, Maeda K, Escobar F, Dori Y, Krishnamurthy G. Lymphatic Interventions and Treatment: Current Techniques and Applications in Pediatric and Adult Patients. Semin Roentgenol. 2025, Dec. 62:150968. doi: 10.1016/j.ro.2025.150968. PMID: 41478131.

Toomey NT, Thomas TE, Hall EJ, Nagaswami C, Alferiev I, Chen JM, Ferrari G, Stachelek SJ, Levy RJ. Vitamin-B6 Pretreated Bovine Pericardial Bioprosthetic Heart Valve Leaflets Demonstrate Reduced Platelet Adhesion and Activation. J Biomed Mater Res  A. 2026, Jan. 114(1): e70020. doi: 10.1002/jbma.70020. PMID: 41481804.

2025

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2023

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* Denotes projects with fellows ** Denotes projects supported by CCRC

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