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Researchers at Children’s Hospital of Philadelphia Reveal New Insights into Non-Inflammatory Causes of Rare Neurological Symptoms in Children, Adolescents and Young Adults Following CAR-T Therapy

Sep 26, 2024
Researchers at Children’s Hospital of Philadelphia (CHOP) revealed for the first time that children, adolescents and young adults may experience very rare neurological issues of paraparesis and quadriparesis following chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy used to treat B-cell Acute Lymphoblastic Leukemia (B-ALL). Additionally, these complications occurred without the type of inflammation typically seen in adults. The findings were published today in the journal Blood.
Young girl studying drinking an energy drink

Researchers at Children’s Hospital of Philadelphia Advocate for Energy Drink Regulation

Sep 4, 2024
Energy drinks, marketed for boosting energy, concentration, and athletic performance, can pose significant cardiovascular risks, including death. Despite the American Academy of Pediatrics’ advice against caffeine consumption by children and adolescents, the United States remains the least regulated country and should take immediate steps to protect vulnerable populations, leading cardiology researchers at Children’s Hospital of Philadelphia (CHOP) urged in a recent commentary in the Journal of Pediatrics.