The purpose of this research study is to collect different types of samples (such as stool, swabs, urine) to form a biorepository. This repository will provide valuable samples from people with and without IBD so that investigators can learn more about the cause of IBD, and different therapies that could be used to treat it. These samples will be used for future gastrointestinal research. Because technology and scientific understanding may advance quickly, it is not yet known what specific studies the samples may be used for.

Children's Hospital of Philadelphia (CHOP) is inviting healthy individuals ages 0-21 to become part of a unique opportunity to help other kids heal: the CHOP Pediatric Fecal Microbiota Transplant (FMT) Stool Bank. This unique program is the first of its kind in the United States and offers screened stool donations from healthy children that may be used to provide life-changing treatment for children suffering from serious gut infections like recurrent C. difficile - an illness that can cause significant symptoms and complications. Contributing to this program could make a direct difference in providing safe and effective treatment options for serious gut infections in children.

This study seeks to characterize dietary intake in children with or without IBS and explore severity of symptoms and quality of life. This study uses the G-Tech wireless patch system to define patterns of gut motility in patients with or without IBS and associate these patterns with dietary intake and GI symptoms. Participants will wear the patches for 7 days as a part of the study. They can be worn under clothing and participants can continue daily activities other than swimming, bathing (although they can shower), and exercising. Stool and urine samples will also be collected to explore the gut microbiome and its association with GI symptoms, diet, and patterns of gut motility.

We are looking to partner with patients with or without a confirmed diagnosis of IBS between 8 and 18 years of age who may also be undergoing dietary modifications such as a low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet.